Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPACEI1827(ACE-inhibitory peptide)

DFBP ID	DFBPACEI1827
Peptide sequence	VPW
Type	Native peptide
Peptide/Function name	ACE-inhibitory peptide

Function-activity relationship

Main bioactivity	ACE-inhibitory activity
Otheir bioactivity	Antioxidative activity ^[D1], Multifunctional activity ^[D2]

Calculated physicochemical properties

Three-letter amino acid

Val-Pro-Trp

Single-letter amino acid

VPW

Peptide length

Peptide mass

Experimental mass	Theoretical mass
400 Da	400.48 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

5.97 ^c

IC₅₀

383 ± 18 μM

pIC₅₀

-2.583

GRAVY

0.5667^c

Hydrophilic residue ratio

100%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Plant
Organism/Source	Chlorella vulgaris (C. vulgaris)
Precursor protein	Uncharacterized membrane protein ycf78 (P56370)
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR0848 ---- Plant proteins ---- Beta-glucosidase 7 Source.2: DFBPPR0861 ---- Plant proteins ---- Calcium-dependent protein kinase 18 Source.3: DFBPPR0905 ---- Plant proteins ---- Deoxyribodipyrimidine photo-lyase Source.4: DFBPPR0923 ---- Plant proteins ---- Lysine-specific demethylase JMJ703 Source.5: DFBPPR0957 ---- Plant proteins ---- Beta-glucosidase 26 Source.6: DFBPPR0962 ---- Plant proteins ---- Transcription factor MYBS3 Source.7: DFBPPR0994 ---- Plant proteins ---- Zinc finger protein HD1 Source.8: DFBPPR1078 ---- Plant proteins ---- Sucrose transport protein SUT5 Source.9: DFBPPR1100 ---- Plant proteins ---- Soluble starch synthase 2-3, chloroplastic/amyloplastic Source.10: DFBPPR1218 ---- Plant proteins ---- Cytochrome P450 90D2 Source.11: DFBPPR1286 ---- Plant proteins ---- Heme oxygenase 1, chloroplastic Source.12: DFBPPR1385 ---- Plant proteins ---- Glutamine synthetase cytosolic isozyme 1-2 Source.13: DFBPPR1487 ---- Plant proteins ---- Beta-1,2-xylosyltransferease XAX1 Source.14: DFBPPR1524 ---- Plant proteins ---- Glutamine synthetase, chloroplastic Source.15: DFBPPR1543 ---- Plant proteins ---- Soluble starch synthase 2-2, chloroplastic/amyloplastic Source.16: DFBPPR1564 ---- Plant proteins ---- Transcription factor PHYTOCHROME INTERACTING FACTOR-LIKE 15 Source.17: DFBPPR1589 ---- Plant proteins ---- Galactinol--sucrose galactosyltransferase Source.18: DFBPPR1672 ---- Plant proteins ---- Alcohol dehydrogenase class-3 Source.19: DFBPPR1690 ---- Plant proteins ---- Transcription factor APG Source.20: DFBPPR1730 ---- Plant proteins ---- DNA repair and recombination protein RAD54 Source.21: DFBPPR1756 ---- Plant proteins ---- Soluble starch synthase 2-1, chloroplastic/amyloplastic Source.22: DFBPPR1764 ---- Plant proteins ---- B3 domain-containing protein VP1 Source.23: DFBPPR1788 ---- Plant proteins ---- Beta-galactosidase 6 Source.24: DFBPPR1891 ---- Plant proteins ---- Transcription factor MYBS2 Source.25: DFBPPR2017 ---- Plant proteins ---- Asparagine synthetase [glutamine-hydrolyzing] 1 Source.26: DFBPPR2115 ---- Plant proteins ---- E3 ubiquitin-protein ligase SIRP1 Source.27: DFBPPR2136 ---- Plant proteins ---- Alpha-1,3-arabinosyltransferase XAT3 Source.28: DFBPPR2166 ---- Plant proteins ---- Eukaryotic translation initiation factor isoform 4G-1 Source.29: DFBPPR2169 ---- Plant proteins ---- Alpha-1,3-arabinosyltransferase XAT2 Source.30: DFBPPR2172 ---- Plant proteins ---- S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase Source.31: DFBPPR2247 ---- Plant proteins ---- Phytochrome C Source.32: DFBPPR2268 ---- Plant proteins ---- Probable glucomannan 4-beta-mannosyltransferase 7 Source.33: DFBPPR2346 ---- Plant proteins ---- Probable tocopherol cyclase, chloroplastic Source.34: DFBPPR2446 ---- Plant proteins ---- Very-long-chain aldehyde decarbonylase GL1-9 Source.35: DFBPPR2513 ---- Plant proteins ---- Beta-glucosidase 25 Source.36: DFBPPR2842 ---- Plant proteins ---- Mannan endo-1,4-beta-mannosidase 6 Source.37: DFBPPR2885 ---- Plant proteins ---- Ammonium transporter 2 member 1 Source.38: DFBPPR2908 ---- Plant proteins ---- Auxin-responsive protein IAA8 Source.39: DFBPPR2955 ---- Plant proteins ---- Probable protein arginine N-methyltransferase 3 Source.40: DFBPPR2997 ---- Plant proteins ---- Beta-galactosidase 13 Source.41: DFBPPR3023 ---- Plant proteins ---- RNA pseudouridine synthase 6, chloroplastic Source.42: DFBPPR3060 ---- Plant proteins ---- Polycomb group protein EMF2A Source.43: DFBPPR3080 ---- Plant proteins ---- Beta-galactosidase 3 Source.44: DFBPPR3092 ---- Plant proteins ---- Beta-galactosidase 12 Source.45: DFBPPR3093 ---- Plant proteins ---- Beta-galactosidase 11 Source.46: DFBPPR3103 ---- Plant proteins ---- Beta-glucosidase 4 Source.47: DFBPPR3112 ---- Plant proteins ---- Auxin-responsive protein IAA6 Source.48: DFBPPR3136 ---- Plant proteins ---- Magnesium/proton exchanger 1 Source.49: DFBPPR3153 ---- Plant proteins ---- Auxin-responsive protein IAA11 Source.50: DFBPPR3188 ---- Plant proteins ---- Auxin-responsive protein IAA27 Source.51: DFBPPR3218 ---- Plant proteins ---- Probable lipoxygenase 6 Source.52: DFBPPR3256 ---- Plant proteins ---- Beta-glucosidase 1 Source.53: DFBPPR3283 ---- Plant proteins ---- Auxin-responsive protein IAA21 Source.54: DFBPPR3308 ---- Plant proteins ---- Auxin-responsive protein IAA26 Source.55: DFBPPR3340 ---- Plant proteins ---- Beta-galactosidase 5 Source.56: DFBPPR3359 ---- Plant proteins ---- Beta-galactosidase 1 Source.57: DFBPPR3363 ---- Plant proteins ---- Beta-galactosidase 2 Source.58: DFBPPR3364 ---- Plant proteins ---- Beta-glucosidase 38 Source.59: DFBPPR3382 ---- Plant proteins ---- Auxin-responsive protein IAA14 Source.60: DFBPPR3386 ---- Plant proteins ---- Auxin-responsive protein IAA2 Source.61: DFBPPR3388 ---- Plant proteins ---- Beta-galactosidase 14 Source.62: DFBPPR3389 ---- Plant proteins ---- Beta-galactosidase 7 Source.63: DFBPPR3392 ---- Plant proteins ---- Auxin-responsive protein IAA9 Source.64: DFBPPR3393 ---- Plant proteins ---- Auxin-responsive protein IAA20 Source.65: DFBPPR3394 ---- Plant proteins ---- Auxin-responsive protein IAA7 Source.66: DFBPPR3404 ---- Plant proteins ---- Auxin-responsive protein IAA3 Source.67: DFBPPR3405 ---- Plant proteins ---- Auxin-responsive protein IAA1 Source.68: DFBPPR3411 ---- Plant proteins ---- Auxin-responsive protein IAA15 Source.69: DFBPPR3422 ---- Plant proteins ---- Putative beta-galactosidase 10 Source.70: DFBPPR3441 ---- Plant proteins ---- Chloroplastic group IIA intron splicing facilitator CRS1, chloroplastic Source.71: DFBPPR3480 ---- Plant proteins ---- Zinc finger CCCH domain-containing protein 4 Source.72: DFBPPR3552 ---- Plant proteins ---- Auxin-responsive protein IAA4 Source.73: DFBPPR3581 ---- Plant proteins ---- Auxin-responsive protein IAA17 Source.74: DFBPPR3594 ---- Plant proteins ---- Auxin-responsive protein IAA10 Source.75: DFBPPR3595 ---- Plant proteins ---- Auxin-responsive protein IAA24 Source.76: DFBPPR3677 ---- Plant proteins ---- Auxin-responsive protein IAA25 Source.77: DFBPPR3692 ---- Plant proteins ---- Protein disulfide isomerase-like 5-1 Source.78: DFBPPR3695 ---- Plant proteins ---- Auxin-responsive protein IAA23 Source.79: DFBPPR3735 ---- Plant proteins ---- Beta-galactosidase 8 Source.80: DFBPPR3743 ---- Plant proteins ---- Putative auxin-responsive protein IAA28 Source.81: DFBPPR3754 ---- Plant proteins ---- Auxin-responsive protein IAA30 Source.82: DFBPPR3782 ---- Plant proteins ---- Auxin-responsive protein IAA16 Source.83: DFBPPR3817 ---- Plant proteins ---- Beta-galactosidase 4 Source.84: DFBPPR3824 ---- Plant proteins ---- Auxin-responsive protein IAA22 Source.85: DFBPPR3839 ---- Plant proteins ---- Eukaryotic translation initiation factor isoform 4G-2 Source.86: DFBPPR3849 ---- Plant proteins ---- Auxin-responsive protein IAA13 Source.87: DFBPPR3944 ---- Plant proteins ---- Magnesium/proton exchanger 2 Source.88: DFBPPR3948 ---- Plant proteins ---- Probable anion transporter 5, chloroplastic Source.89: DFBPPR4011 ---- Plant proteins ---- Sugar transport protein MST1 Source.90: DFBPPR4021 ---- Plant proteins ---- Phosphopantothenate--cysteine ligase 2 Source.91: DFBPPR4052 ---- Plant proteins ---- Beta-galactosidase 9 Source.92: DFBPPR4091 ---- Plant proteins ---- Putative auxin-responsive protein IAA29 Source.93: DFBPPR4099 ---- Plant proteins ---- Cycloartenol-C-24-methyltransferase 1 Source.94: DFBPPR4283 ---- Plant proteins ---- SCAR-like protein 1 Source.95: DFBPPR4306 ---- Plant proteins ---- Phosphopantothenate--cysteine ligase 1 Source.96: DFBPPR4391 ---- Plant proteins ---- Maltose excess protein 1-like, chloroplastic Source.97: DFBPPR4411 ---- Plant proteins ---- Ammonium transporter 2 member 2 Source.98: DFBPPR4437 ---- Plant proteins ---- Ricin B-like lectin R40C1 Source.99: DFBPPR4448 ---- Plant proteins ---- Probable sodium/metabolite cotransporter BASS4, chloroplastic Source.100: DFBPPR4555 ---- Plant proteins ---- Actin-related protein 9 Source.101: DFBPPR4603 ---- Plant proteins ---- Tubby-like F-box protein 2 Source.102: DFBPPR4930 ---- Plant proteins ---- Cytochrome b6-f complex iron-sulfur subunit, chloroplastic Source.103: DFBPPR5077 ---- Plant proteins ---- Digalactosyldiacylglycerol synthase 1, chloroplastic Source.104: DFBPPR5181 ---- Plant proteins ---- Glutamine synthetase cytosolic isozyme 1 Source.105: DFBPPR5265 ---- Plant proteins ---- Auxin-induced protein AUX22 Source.106: DFBPPR5271 ---- Plant proteins ---- Auxin-induced protein AUX28 Source.107: DFBPPR5313 ---- Plant proteins ---- CASP-like protein 1D1 Source.108: DFBPPR5315 ---- Plant proteins ---- CASP-like protein 1D2 Source.109: DFBPPR5426 ---- Plant proteins ---- Dimethylnonatriene synthase Source.110: DFBPPR5454 ---- Plant proteins ---- Ferredoxin-dependent glutamate synthase, chloroplastic Source.111: DFBPPR5495 ---- Plant proteins ---- Trimethyltridecatetraene synthase Source.112: DFBPPR5538 ---- Plant proteins ---- Alcohol dehydrogenase class-3 Source.113: DFBPPR5565 ---- Plant proteins ---- Chloroplastic group IIA intron splicing facilitator CRS1, chloroplastic Source.114: DFBPPR5616 ---- Plant proteins ---- Triosephosphate isomerase, cytosolic Source.115: DFBPPR5700 ---- Plant proteins ---- Glutamine synthetase root isozyme 5 Source.116: DFBPPR5703 ---- Plant proteins ---- Asparagine synthetase [glutamine-hydrolyzing] Source.117: DFBPPR5704 ---- Plant proteins ---- Glutamine synthetase root isozyme 1 Source.118: DFBPPR5726 ---- Plant proteins ---- Glutamine synthetase, chloroplastic Source.119: DFBPPR5803 ---- Plant proteins ---- Anthocyanidin 3-O-glucosyltransferase Source.120: DFBPPR5810 ---- Plant proteins ---- Anthocyanidin 3-O-glucosyltransferase Source.121: DFBPPR5858 ---- Plant proteins ---- DNA-directed RNA polymerase subunit beta'' Source.122: DFBPPR5869 ---- Plant proteins ---- Anthocyanin regulatory Lc protein Source.123: DFBPPR5910 ---- Plant proteins ---- Anthocyanin regulatory R-S protein Source.124: DFBPPR5936 ---- Plant proteins ---- Indole-3-acetate beta-glucosyltransferase Source.125: DFBPPR6018 ---- Plant proteins ---- Probable tocopherol cyclase, chloroplastic Source.126: DFBPPR6211 ---- Plant proteins ---- Anthocyanidin 3-O-glucosyltransferase Source.127: DFBPPR6235 ---- Plant proteins ---- Alcohol dehydrogenase class-3 Source.128: DFBPPR6253 ---- Plant proteins ---- Stachyose synthase Source.129: DFBPPR6321 ---- Plant proteins ---- Cytochrome b6-f complex iron-sulfur subunit, chloroplastic Source.130: DFBPPR6339 ---- Plant proteins ---- Phytochrome A Source.131: DFBPPR6347 ---- Plant proteins ---- Granule-bound starch synthase 2, chloroplastic/amyloplastic Source.132: DFBPPR6389 ---- Plant proteins ---- Auxin-induced protein IAA4 Source.133: DFBPPR6400 ---- Plant proteins ---- Glutamine synthetase root isozyme A Source.134: DFBPPR6416 ---- Plant proteins ---- Glutamine synthetase root isozyme B Source.135: DFBPPR6509 ---- Plant proteins ---- Auxin-induced protein IAA6 Source.136: DFBPPR6571 ---- Plant proteins ---- Small heat shock protein, chloroplastic Source.137: DFBPPR6666 ---- Plant proteins ---- Cytochrome b6-f complex iron-sulfur subunit, chloroplastic Source.138: DFBPPR6839 ---- Plant proteins ---- DNA-directed RNA polymerase subunit beta'' Source.139: DFBPPR6927 ---- Plant proteins ---- Eukaryotic translation initiation factor isoform 4G-1 Source.140: DFBPPR6952 ---- Plant proteins ---- Eukaryotic translation initiation factor isoform 4G-2 Source.141: DFBPPR7027 ---- Plant proteins ---- Chlorophyll a-b binding protein 1B-21, chloroplastic Source.142: DFBPPR7051 ---- Plant proteins ---- Triosephosphate isomerase, cytosolic Source.143: DFBPPR7104 ---- Plant proteins ---- Glutamine synthetase leaf isozyme, chloroplastic Source.144: DFBPPR7205 ---- Plant proteins ---- DNA-directed RNA polymerase subunit beta'' Source.145: DFBPPR7213 ---- Plant proteins ---- Anthocyanidin 3-O-glucosyltransferase Source.146: DFBPPR7402 ---- Plant proteins ---- Probable pectinesterase/pectinesterase inhibitor Source.147: DFBPPR7621 ---- Milk proteins ---- Mucin-4 Source.148: DFBPPR7631 ---- Milk proteins ---- Zinc-alpha-2-glycoprotein Source.149: DFBPPR7641 ---- Milk proteins ---- Lactase-phlorizin hydrolase Source.150: DFBPPR8390 ---- Plant proteins ---- Galactose-binding lectin Source.151: DFBPPR8502 ---- Milk proteins ---- Broad substrate specificity ATP-binding cassette transporter ABCG2 Source.152: DFBPPR15945 ---- Animal proteins ---- Dopamine beta-hydroxylase Source.153: DFBPPR15966 ---- Animal proteins ---- Cystic fibrosis transmembrane conductance regulator Source.154: DFBPPR15985 ---- Animal proteins ---- von Willebrand factor Source.155: DFBPPR15993 ---- Animal proteins ---- Sodium/myo-inositol cotransporter Source.156: DFBPPR16016 ---- Animal proteins ---- Nitric oxide synthase, endothelial Source.157: DFBPPR16039 ---- Animal proteins ---- Breast cancer type 1 susceptibility protein homolog Source.158: DFBPPR16063 ---- Animal proteins ---- Receptor tyrosine-protein kinase erbB-2 Source.159: DFBPPR16099 ---- Animal proteins ---- Alpha-ketoglutarate-dependent dioxygenase FTO Source.160: DFBPPR16104 ---- Animal proteins ---- Retinal guanylyl cyclase 1 Source.161: DFBPPR16147 ---- Animal proteins ---- Telomerase reverse transcriptase Source.162: DFBPPR16180 ---- Animal proteins ---- Orexin Source.163: DFBPPR16211 ---- Animal proteins ---- Lysine-specific demethylase 5C Source.164: DFBPPR16213 ---- Animal proteins ---- Ciliary neurotrophic factor receptor subunit alpha Source.165: DFBPPR16232 ---- Animal proteins ---- Lysine-specific demethylase 5D Source.166: DFBPPR16263 ---- Animal proteins ---- Protein 4.1 Source.167: DFBPPR16382 ---- Animal proteins ---- Platelet glycoprotein Ib alpha chain Source.168: DFBPPR16644 ---- Animal proteins ---- Arylsulfatase H Source.169: DFBPPR16675 ---- Animal proteins ---- V-type proton ATPase subunit e 1 Source.170: DFBPPR16690 ---- Animal proteins ---- Trefoil factor 3 Source.171: DFBPPR16707 ---- Animal proteins ---- Trefoil factor 2 Source.172: DFBPPR16737 ---- Animal proteins ---- Trefoil factor 1 Source.173: DFBPPR16805 ---- Animal proteins ---- Dopamine beta-hydroxylase Source.174: DFBPPR16822 ---- Animal proteins ---- Kininogen-2 Source.175: DFBPPR16830 ---- Animal proteins ---- Kininogen-1 Source.176: DFBPPR16871 ---- Animal proteins ---- Plasminogen Source.177: DFBPPR16876 ---- Animal proteins ---- Metalloproteinase inhibitor 2 Source.178: DFBPPR16971 ---- Animal proteins ---- Galactoside alpha-(1,2)-fucosyltransferase 2 Source.179: DFBPPR16983 ---- Animal proteins ---- Membrane primary amine oxidase Source.180: DFBPPR17048 ---- Animal proteins ---- Nitric oxide synthase, endothelial Source.181: DFBPPR17068 ---- Animal proteins ---- Mitogen-activated protein kinase 1 Source.182: DFBPPR17156 ---- Animal proteins ---- ATP-dependent RNA helicase A Source.183: DFBPPR17289 ---- Animal proteins ---- Receptor-interacting serine/threonine-protein kinase 2 Source.184: DFBPPR17312 ---- Animal proteins ---- Mitogen-activated protein kinase 7 Source.185: DFBPPR17313 ---- Animal proteins ---- Exostosin-1 Source.186: DFBPPR17320 ---- Animal proteins ---- Acid ceramidase Source.187: DFBPPR17423 ---- Animal proteins ---- Furin Source.188: DFBPPR17437 ---- Animal proteins ---- DNA excision repair protein ERCC-1 Source.189: DFBPPR17488 ---- Animal proteins ---- Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 Source.190: DFBPPR17490 ---- Animal proteins ---- TIR domain-containing adapter molecule 2 Source.191: DFBPPR17540 ---- Animal proteins ---- Breast cancer type 1 susceptibility protein homolog Source.192: DFBPPR17718 ---- Animal proteins ---- Activin receptor type-2B Source.193: DFBPPR17742 ---- Animal proteins ---- Primary amine oxidase, lung isozyme Source.194: DFBPPR17830 ---- Animal proteins ---- Vasopressin V2 receptor Source.195: DFBPPR17853 ---- Animal proteins ---- [F-actin]-monooxygenase MICAL3 Source.196: DFBPPR17916 ---- Animal proteins ---- E3 ubiquitin-protein ligase RNF126 Source.197: DFBPPR17930 ---- Animal proteins ---- Dual serine/threonine and tyrosine protein kinase Source.198: DFBPPR17931 ---- Animal proteins ---- Alpha-actinin-3 Source.199: DFBPPR17972 ---- Animal proteins ---- Telomerase reverse transcriptase Source.200: DFBPPR18042 ---- Animal proteins ---- Acyl-CoA desaturase Source.201: DFBPPR18074 ---- Animal proteins ---- Beta-3 adrenergic receptor Source.202: DFBPPR18126 ---- Animal proteins ---- RNA polymerase II-associated factor 1 homolog Source.203: DFBPPR18156 ---- Animal proteins ---- Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 Source.204: DFBPPR18217 ---- Animal proteins ---- Alkylated DNA repair protein alkB homolog 8 Source.205: DFBPPR18233 ---- Animal proteins ---- Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 Source.206: DFBPPR18253 ---- Animal proteins ---- BOLA class I histocompatibility antigen, alpha chain BL3-7 Source.207: DFBPPR18427 ---- Animal proteins ---- Cystatin-C Source.208: DFBPPR18429 ---- Animal proteins ---- Pre-mRNA-splicing factor SLU7 Source.209: DFBPPR18534 ---- Animal proteins ---- M-phase inducer phosphatase 3 Source.210: DFBPPR18574 ---- Animal proteins ---- Stearoyl-CoA desaturase 5 Source.211: DFBPPR18599 ---- Animal proteins ---- Beta-1,4-glucuronyltransferase 1 Source.212: DFBPPR19158 ---- Animal proteins ---- Tuberoinfundibular peptide of 39 residues Source.213: DFBPPR19220 ---- Animal proteins ---- Nicotinate phosphoribosyltransferase Source.214: DFBPPR19253 ---- Animal proteins ---- Limbin Source.215: DFBPPR19284 ---- Animal proteins ---- Protein lifeguard 2 Source.216: DFBPPR19320 ---- Animal proteins ---- Palmitoyl-protein thioesterase ABHD10, mitochondrial Source.217: DFBPPR19611 ---- Animal proteins ---- Phenylalanine-4-hydroxylase Source.218: DFBPPR19634 ---- Animal proteins ---- Branched-chain-amino-acid aminotransferase, mitochondrial Source.219: DFBPPR19688 ---- Animal proteins ---- TBC1 domain family member 2A Source.220: DFBPPR19697 ---- Animal proteins ---- Sodium/myo-inositol cotransporter Source.221: DFBPPR19798 ---- Animal proteins ---- Uricase Source.222: DFBPPR19801 ---- Animal proteins ---- Outer dense fiber protein 2 Source.223: DFBPPR19872 ---- Animal proteins ---- Glucose-6-phosphatase 3 Source.224: DFBPPR19926 ---- Animal proteins ---- Gamma-interferon-inducible lysosomal thiol reductase Source.225: DFBPPR20069 ---- Animal proteins ---- Glycogen [starch] synthase, muscle Source.226: DFBPPR20366 ---- Animal proteins ---- Protein phosphatase methylesterase 1 Source.227: DFBPPR20389 ---- Animal proteins ---- Leucine-rich repeat-containing protein 7 Source.228: DFBPPR20408 ---- Animal proteins ---- Phospholipid scramblase 2 Source.229: DFBPPR20510 ---- Animal proteins ---- Josephin-1 Source.230: DFBPPR20779 ---- Animal proteins ---- Myelin regulatory factor-like protein Source.231: DFBPPR20917 ---- Animal proteins ---- RNA binding protein fox-1 homolog 3 Source.232: DFBPPR20963 ---- Animal proteins ---- Protein kintoun Source.233: DFBPPR21016 ---- Animal proteins ---- Little elongation complex subunit 2 Source.234: DFBPPR21075 ---- Animal proteins ---- Constitutive coactivator of PPAR-gamma-like protein 1 Source.235: DFBPPR21187 ---- Animal proteins ---- Plasmolipin Source.236: DFBPPR21191 ---- Animal proteins ---- RAS protein activator like-3 Source.237: DFBPPR21199 ---- Animal proteins ---- Trans-L-3-hydroxyproline dehydratase Source.238: DFBPPR21262 ---- Animal proteins ---- Probable tRNA methyltransferase 9B Source.239: DFBPPR21323 ---- Animal proteins ---- Trefoil factor 3 Source.240: DFBPPR21364 ---- Animal proteins ---- Rho guanine nucleotide exchange factor 10-like protein Source.241: DFBPPR21403 ---- Animal proteins ---- Zinc-alpha-2-glycoprotein Source.242: DFBPPR21434 ---- Animal proteins ---- Ankyrin repeat and SOCS box protein 15 Source.243: DFBPPR21440 ---- Animal proteins ---- Regulator of microtubule dynamics protein 1 Source.244: DFBPPR21443 ---- Animal proteins ---- CKLF-like MARVEL transmembrane domain-containing protein 8 Source.245: DFBPPR21714 ---- Animal proteins ---- tRNA (guanine(10)-N2)-methyltransferase homolog Source.246: DFBPPR21752 ---- Animal proteins ---- Major facilitator superfamily domain-containing protein 10 Source.247: DFBPPR21830 ---- Animal proteins ---- Guanine nucleotide exchange factor for Rab-3A Source.248: DFBPPR21886 ---- Animal proteins ---- Interferon-stimulated 20 kDa exonuclease-like 2 Source.249: DFBPPR22056 ---- Animal proteins ---- dTDP-D-glucose 4,6-dehydratase Source.250: DFBPPR22316 ---- Animal proteins ---- MAPK-interacting and spindle-stabilizing protein-like Source.251: DFBPPR22320 ---- Animal proteins ---- Transmembrane protein 229B Source.252: DFBPPR22357 ---- Animal proteins ---- Transmembrane protein 180 Source.253: DFBPPR22472 ---- Animal proteins ---- Aldehyde dehydrogenase family 16 member A1 Source.254: DFBPPR22521 ---- Animal proteins ---- Protein OSCP1 Source.255: DFBPPR22580 ---- Animal proteins ---- Paraneoplastic antigen-like protein 8A Source.256: DFBPPR22668 ---- Animal proteins ---- Protein FAM243 Source.257: DFBPPR22677 ---- Animal proteins ---- Uncharacterized protein CXorf49 homolog Source.258: DFBPPR22739 ---- Animal proteins ---- Testis, prostate and placenta-expressed protein Source.259: DFBPPR8724 ---- Animal proteins ---- Nitric oxide synthase, endothelial Source.260: DFBPPR8726 ---- Animal proteins ---- Serine-protein kinase ATM Source.261: DFBPPR8794 ---- Animal proteins ---- NPC intracellular cholesterol transporter 1 Source.262: DFBPPR8821 ---- Animal proteins ---- Beta-3 adrenergic receptor Source.263: DFBPPR9071 ---- Animal proteins ---- Nuclear receptor coactivator 1 Source.264: DFBPPR9074 ---- Animal proteins ---- Trefoil factor 2 Source.265: DFBPPR9105 ---- Animal proteins ---- Lysine-specific demethylase 5C Source.266: DFBPPR9166 ---- Animal proteins ---- Uricase Source.267: DFBPPR9206 ---- Animal proteins ---- Serine/threonine-protein phosphatase 1 regulatory subunit 10 Source.268: DFBPPR9336 ---- Animal proteins ---- Cholesterol 25-hydroxylase Source.269: DFBPPR9380 ---- Animal proteins ---- Gamma-interferon-inducible-lysosomal thiol reductase Source.270: DFBPPR9394 ---- Animal proteins ---- 5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase Source.271: DFBPPR9410 ---- Animal proteins ---- Acyl-CoA desaturase Source.272: DFBPPR9411 ---- Animal proteins ---- Acyl-CoA desaturase Source.273: DFBPPR9412 ---- Animal proteins ---- Acyl-CoA desaturase Source.274: DFBPPR9580 ---- Animal proteins ---- Mediator of DNA damage checkpoint protein 1 Source.275: DFBPPR9670 ---- Animal proteins ---- NF-kappa-B inhibitor-like protein 1 Source.276: DFBPPR9702 ---- Animal proteins ---- Branched-chain-amino-acid aminotransferase, mitochondrial Source.277: DFBPPR9758 ---- Animal proteins ---- Galanin-like peptide Source.278: DFBPPR9880 ---- Animal proteins ---- Trefoil factor 3 Source.279: DFBPPR10029 ---- Animal proteins ---- Activin receptor type-2B Source.280: DFBPPR10125 ---- Animal proteins ---- Leucine-rich repeat transmembrane protein FLRT3 Source.281: DFBPPR10168 ---- Animal proteins ---- TALPID3 protein Source.282: DFBPPR10251 ---- Animal proteins ---- Integrin alpha-6 Source.283: DFBPPR10534 ---- Animal proteins ---- DNA ligase 4 Source.284: DFBPPR10542 ---- Animal proteins ---- Erythroid transcription factor Source.285: DFBPPR10759 ---- Animal proteins ---- Phosphoethanolamine/phosphocholine phosphatase Source.286: DFBPPR10781 ---- Animal proteins ---- Inhibin alpha chain Source.287: DFBPPR10935 ---- Animal proteins ---- Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 Source.288: DFBPPR11450 ---- Animal proteins ---- Potassium voltage-gated channel subfamily G member 2 Source.289: DFBPPR11553 ---- Animal proteins ---- V-type proton ATPase 116 kDa subunit a1 Source.290: DFBPPR11704 ---- Animal proteins ---- Pre-mRNA-splicing factor SLU7 Source.291: DFBPPR11705 ---- Animal proteins ---- SCO-spondin Source.292: DFBPPR11793 ---- Animal proteins ---- Fas-binding factor 1 homolog Source.293: DFBPPR12088 ---- Animal proteins ---- Kelch-like protein 14 Source.294: DFBPPR12092 ---- Animal proteins ---- Protein MMS22-like Source.295: DFBPPR12101 ---- Animal proteins ---- Highly divergent homeobox Source.296: DFBPPR12253 ---- Animal proteins ---- Aldehyde oxidase 1 Source.297: DFBPPR12275 ---- Animal proteins ---- Ryanodine receptor 3 Source.298: DFBPPR12285 ---- Animal proteins ---- Galactoside alpha-(1,2)-fucosyltransferase 2 Source.299: DFBPPR12409 ---- Animal proteins ---- Glycogen [starch] synthase, muscle Source.300: DFBPPR12444 ---- Animal proteins ---- C->U-editing enzyme APOBEC-1 Source.301: DFBPPR12453 ---- Animal proteins ---- Lactase-phlorizin hydrolase Source.302: DFBPPR12615 ---- Animal proteins ---- Metalloproteinase inhibitor 1 Source.303: DFBPPR12725 ---- Animal proteins ---- Uricase Source.304: DFBPPR12732 ---- Animal proteins ---- Tryptophan 5-hydroxylase 1 Source.305: DFBPPR12869 ---- Animal proteins ---- Metalloproteinase inhibitor 2 Source.306: DFBPPR13000 ---- Animal proteins ---- Cystatin-C Source.307: DFBPPR13065 ---- Animal proteins ---- Tartrate-resistant acid phosphatase type 5 Source.308: DFBPPR13194 ---- Animal proteins ---- Dopamine beta-hydroxylase Source.309: DFBPPR13272 ---- Animal proteins ---- Carnitine O-palmitoyltransferase 1, liver isoform Source.310: DFBPPR13295 ---- Animal proteins ---- Alpha-1-antiproteinase 2 Source.311: DFBPPR13327 ---- Animal proteins ---- Metalloproteinase inhibitor 2 Source.312: DFBPPR13373 ---- Animal proteins ---- Tryptophan 5-hydroxylase 2 Source.313: DFBPPR13406 ---- Animal proteins ---- Cortactin-binding protein 2 Source.314: DFBPPR13451 ---- Animal proteins ---- Beta-3 adrenergic receptor Source.315: DFBPPR13467 ---- Animal proteins ---- Acyl-CoA desaturase Source.316: DFBPPR13634 ---- Animal proteins ---- Beta-3 adrenergic receptor Source.317: DFBPPR13674 ---- Animal proteins ---- Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 Source.318: DFBPPR13713 ---- Animal proteins ---- Plasminogen Source.319: DFBPPR13731 ---- Animal proteins ---- Acyl-CoA desaturase Source.320: DFBPPR13877 ---- Animal proteins ---- Sialin Source.321: DFBPPR13947 ---- Animal proteins ---- Cortactin-binding protein 2 Source.322: DFBPPR14006 ---- Animal proteins ---- Acyl-CoA desaturase Source.323: DFBPPR14337 ---- Marine protein ---- Photosystem I iron-sulfur center Source.324: DFBPPR14622 ---- Marine protein ---- Band 3 anion exchange protein Source.325: DFBPPR15000 ---- Microorganism protein ---- D-lactate dehydrogenase [cytochrome], mitochondrial Source.326: DFBPPR15041 ---- Microorganism protein ---- Autophagy protein 5 Source.327: DFBPPR15138 ---- Microorganism protein ---- GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase Source.328: DFBPPR15230 ---- Microorganism protein ---- Histone acetyltransferase type B subunit 2 Source.329: DFBPPR15245 ---- Microorganism protein ---- Cytochrome c oxidase assembly protein COX18, mitochondrial Source.330: DFBPPR15314 ---- Microorganism protein ---- Probable metalloprotease ARX1 Source.331: DFBPPR15316 ---- Microorganism protein ---- Protein URE2 Source.332: DFBPPR15615 ---- Microorganism protein ---- Probable transporter MCH1 Source.333: DFBPPR15782 ---- Microorganism protein ---- Uncharacterized killer plasmid pGKl-2 protein 3 Source.334: DFBPPR7751 ---- Plant protein ---- Cyanohydrin beta-glucosyltransferase Source.335: DFBPPR7760 ---- Plant protein ---- Tyrosine N-monooxygenase Source.336: DFBPPR7818 ---- Plant protein ---- DNA-directed RNA polymerase subunit beta'' Source.337: DFBPPR7825 ---- Plant protein ---- Phytochrome C Source.338: DFBPPR8032 ---- Plant protein ---- Alpha-amylase inhibitor 1 Source.339: DFBPPR8056 ---- Plant protein ---- Glutamine synthetase leaf isozyme, chloroplastic Source.340: DFBPPR8089 ---- Plant protein ---- Glutamine synthetase PR-2 Source.341: DFBPPR8092 ---- Plant protein ---- Alpha-amylase inhibitor 2
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

ACE-inhibitory activity	The peptide exhibited moderate Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) inhibitory activity with an IC₅₀ value of 383 ± 18 μM.
Specific target protein(s)	Specific Target Protein(s): Angiotensin-converting enzyme

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Bitter taste ^prediction

SMILES

N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)O

Preparation method

Mode of preparation	Enzymatic hydrolysis
Enzyme(s)/starter culture	The ACE inhibitory peptide was in silico screened from the product generated by virtual gastrointestinal digestion of the proteins from C. vulgaris.

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

DFBP

[D1]	DFBPANOX0346
[D2]	DFBPMUFU0542

[D3]

[D4]

[D5]

[D6]

Reference(s)

Primary literature	Xie J, Chen X, Wu J, Zhang Y, Zhou Y, Zhang L, Tang YJ, Wei D. Antihypertensive Effects, Molecular Docking Study, and Isothermal Titration Calorimetry Assay of Angiotensin I-Converting Enzyme Inhibitory Peptides from Chlorella vulgaris. J Agric Food Chem. 2018 Feb 14;66(6):1359-1368. PMID: 29345929 DOI: 10.1021/acs.jafc.7b04294
Other literature(s)	N.D
PubDate	2018