Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPAMIC0331(Antimicrobial peptide)

DFBP ID	DFBPAMIC0331
Peptide sequence	EQLTK
Type	Native peptide
Peptide/Function name	Antimicrobial peptide, LTD 1

Function-activity relationship

Main bioactivity	Antimicrobial activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

Glu-Gln-Leu-Thr-Lys

Single-letter amino acid

EQLTK

Peptide length

Peptide mass

Experimental mass	Theoretical mass
N.D	617.70 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

6.92 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

-1.5600^c

Hydrophilic residue ratio

20%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Animal
Organism/Source	Bos taurus (Bovine)
Precursor protein	α-Lactalbumin
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR2030 ---- Plant proteins ---- 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), chloroplastic Source.2: DFBPPR7193 ---- Plant proteins ---- Endoplasmin homolog Source.3: DFBPPR7685 ---- Milk proteins ---- Alpha-lactalbumin Source.4: DFBPPR7697 ---- Milk proteins ---- Alpha-lactalbumin Source.5: DFBPPR7711 ---- Milk proteins ---- Alpha-lactalbumin Source.6: DFBPPR8490 ---- Milk proteins ---- Alpha-lactalbumin Source.7: DFBPPR17348 ---- Animal proteins ---- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 Source.8: DFBPPR10011 ---- Animal proteins ---- Myosin-11 Source.9: DFBPPR10027 ---- Animal proteins ---- Voltage-dependent L-type calcium channel subunit alpha-1D Source.10: DFBPPR12167 ---- Animal proteins ---- Protein odr-4 homolog Source.11: DFBPPR14361 ---- Marine protein ---- Acetolactate synthase small subunit Source.12: DFBPPR15215 ---- Microorganism protein ---- Protein transport protein SEC24
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

Antimicrobial activity	Activity against B. bronchiseptica WS, B. subtilis BGA, M. luteus ATCC 4698, S. epidermidis ATCC 12228, S. lentus WS and S. zooepidemicus ^[1].
Specific target protein(s)	N.D

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Non-bitter taste ^prediction

SMILES

N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CCCCN)C(=O)O

Preparation method

Mode of preparation	Synthesis
Enzyme(s)/starter culture	No enzyme

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Pellegrini A, Thomas U, Bramaz N, Hunziker P, von Fellenberg R. Isolation and identification of three bactericidal domains in the bovine alpha-lactalbumin molecule. Biochim Biophys Acta. 1999 Feb 2;1426(3):439-48. PMID: 10076060 DOI: 10.1016/s0304-4165(98)00165-2
Other literature(s)	N.D
PubDate	1999