DFBP ID - DFBPAMIC0490(Antimicrobial peptide)

DFBP ID DFBPAMIC0490 Peptide sequence STVATL Type Native peptide Peptide/Function name Antimicrobial peptide

Function-activity relationship

Main bioactivity Antimicrobial activity Otheir bioactivity N.D

Calculated physicochemical properties

Three-letter amino acid Ser-Thr-Val-Ala-Thr-Leu Single-letter amino acid STVATL Peptide length 6 Peptide mass Experimental mass Theoretical mass N.D 590.66 Da c Net charge 0.00 c Isoelectric point (pI) 5.97 c IC50 N.D pIC50 N.D GRAVY 1.2667 c Hydrophilic residue ratio 50% c Peptide calculator To calculate the physicochemical properties of bioactive peptide.

Peptide source & Food-borne protein(s) search

Classification Animal Organism/Source Bovine Precursor protein κ-Casein Residue position f(141-146) Precursor protein(s) search Source.1: DFBPPR4420 ---- Plant proteins ---- Membrane-anchored ubiquitin-fold protein 1 Source.2: DFBPPR8492 ---- Milk proteins ---- Kappa-casein Link-research Inductive analysis There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

Antimicrobial activity Antimicrobial activity Specific target protein(s) N.D

Taste properties & Structure

Bitterness Literature report N.D Bitter prediction tools Non-bitter taste prediction SMILES N[C@@]([H])(CO)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)O

Preparation method

Mode of preparation Enzymatic hydrolysis Enzyme(s)/starter culture Peptide obtained by hydrolysis of bovine Kappa-casein by use of  pepsin.

Stability & Cytotoxicity

Peptide stability Literature report: N.D EHP-Tool: Enzymatic Hydrolysis Prediction Tool (EHP-Tool) Peptide cytotoxicity Literature report: N.D Prediction: ToxinPred

Additional information

Additional information N.D

Database cross-references

BIOPEP-UWM [D1] 8265

APD [D2] -

BioPepDB [D3] -

MBPDB [D4] -

Reference(s)

Primary literature López-Expósito I, Minervini F, Amigo L, Recio I. Identification of antibacterial peptides from bovine kappa-casein. J Food Prot. 2006 Dec;69(12):2992-7. PMID: 17186669 DOI: 10.4315/0362-028x-69.12.2992 Other literature(s) N.D PubDate 2006