Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPANCA0086(Anticancer peptide)

DFBP ID	DFBPANCA0086
Peptide sequence	EQRPR
Type	Native peptide
Peptide/Function name	Anticancer peptide

Function-activity relationship

Main bioactivity	Anticancer activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

Glu-Gln-Arg-Pro-Arg

Single-letter amino acid

EQRPR

Peptide length

Peptide mass

Experimental mass	Theoretical mass
N.D	684.75 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

10.88 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

-3.5200^c

Hydrophilic residue ratio

20%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Plant
Organism/Source	Rice
Precursor protein	Rice bran
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR1447 ---- Plant proteins ---- Two-component response regulator-like PRR37 Source.2: DFBPPR2672 ---- Plant proteins ---- 63 kDa globulin-like protein Source.3: DFBPPR3466 ---- Plant proteins ---- Two-component response regulator-like PRR73 Source.4: DFBPPR4130 ---- Plant proteins ---- Two-component response regulator-like PRR95 Source.5: DFBPPR4633 ---- Plant proteins ---- B3 domain-containing protein Os07g0183700 Source.6: DFBPPR17961 ---- Animal proteins ---- Cyclin-dependent kinase 12 Source.7: DFBPPR21749 ---- Animal proteins ---- Protein CUSTOS Source.8: DFBPPR14303 ---- Marine protein ---- Phycobilisome rod-core linker polypeptide cpcG
Link-research Inductive analysis	Link 1: DFBPANCA0008----Rice----Rice bran protein

Biological/Functional activity & target protein

Anticancer activity	The peptide showed anticancer activity.
Specific target protein(s)	N.D

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Non-bitter taste ^prediction

SMILES

N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

Preparation method

Mode of preparation	Synthesis
Enzyme(s)/starter culture	Synthesis peptide

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Kannan A, Hettiarachchy NS, Lay JO, Liyanage R. Human cancer cell proliferation inhibition by a pentapeptide isolated and characterized from rice bran. Peptides. 2010 Sep;31(9):1629-34. PMID: 20594954 DOI: 10.1016/j.peptides.2010.05.018
Other literature(s)	N.D
PubDate	2010