The systolic blood pressure (SBP) and diastolic blood pressure (SBP) in SHRs were lowered significantly (P < 0.05) from the second week of oral administration of Coconut cake globulin hydrolysates-E fraction ( CCGH-E 50, 100 and 200 mg/kg). The middle dose and high dose of CCGH-E exhibited no significant difference in antihypertensive effect compared to captopril. The peptide was obtained from the hyrolysate and showed potent
Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) inhibitory activity,
so it may be a potenial antihypertensive peptide.
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