Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPANHY0514(Antihypertensive peptide)

DFBP ID	DFBPANHY0514
Peptide sequence	IKW
Type	Native peptide
Peptide/Function name	Antihypertensive peptide

Function-activity relationship

Main bioactivity	Antihypertensive activity
Otheir bioactivity	ACE-inhibitory activity ^[D1], Multifunctional activity ^[D2]

Calculated physicochemical properties

Three-letter amino acid

Ile-Lys-Trp

Single-letter amino acid

IKW

Peptide length

Peptide mass

Experimental mass	Theoretical mass
N.D	445.56 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

10.04 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

-0.1000^c

Hydrophilic residue ratio

66.67%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Animal
Organism/Source	Chicken
Precursor protein	Muscle protein
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR0925 ---- Plant proteins ---- Hexokinase-6 Source.2: DFBPPR0953 ---- Plant proteins ---- Hexokinase-5 Source.3: DFBPPR1077 ---- Plant proteins ---- Hexokinase-9 Source.4: DFBPPR1079 ---- Plant proteins ---- Hexokinase-7 Source.5: DFBPPR1130 ---- Plant proteins ---- Hexokinase-4, chloroplastic Source.6: DFBPPR1264 ---- Plant proteins ---- DNA (cytosine-5)-methyltransferase 1A Source.7: DFBPPR1333 ---- Plant proteins ---- Endoglucanase 2 Source.8: DFBPPR1380 ---- Plant proteins ---- Peroxisomal (S)-2-hydroxy-acid oxidase GLO2 Source.9: DFBPPR1400 ---- Plant proteins ---- Cellulose synthase-like protein D4 Source.10: DFBPPR1414 ---- Plant proteins ---- Cellulose synthase-like protein D1 Source.11: DFBPPR1437 ---- Plant proteins ---- Topoisomerase 6 subunit A3 Source.12: DFBPPR1458 ---- Plant proteins ---- Endoglucanase 9 Source.13: DFBPPR1489 ---- Plant proteins ---- Protein SUBSTANDARD STARCH GRAIN 4, chloroplastic Source.14: DFBPPR1605 ---- Plant proteins ---- Phytochrome B Source.15: DFBPPR1730 ---- Plant proteins ---- DNA repair and recombination protein RAD54 Source.16: DFBPPR1734 ---- Plant proteins ---- Probable mixed-linked glucan synthase 9 Source.17: DFBPPR1795 ---- Plant proteins ---- Tubulin gamma-2 chain Source.18: DFBPPR1860 ---- Plant proteins ---- Kinesin-like protein KIN-7A Source.19: DFBPPR1868 ---- Plant proteins ---- Inosine triphosphate pyrophosphatase Source.20: DFBPPR2105 ---- Plant proteins ---- Cellulose synthase-like protein D2 Source.21: DFBPPR2121 ---- Plant proteins ---- Cellulose synthase-like protein D5 Source.22: DFBPPR2158 ---- Plant proteins ---- 1-aminocyclopropane-1-carboxylate synthase 1 Source.23: DFBPPR2171 ---- Plant proteins ---- Probable mixed-linked glucan synthase 8 Source.24: DFBPPR2200 ---- Plant proteins ---- COBRA-like protein 5 Source.25: DFBPPR2211 ---- Plant proteins ---- Probable mixed-linked glucan synthase 3 Source.26: DFBPPR2247 ---- Plant proteins ---- Phytochrome C Source.27: DFBPPR2397 ---- Plant proteins ---- Dehydration-responsive element-binding protein 2A Source.28: DFBPPR2570 ---- Plant proteins ---- Endoglucanase 12 Source.29: DFBPPR2644 ---- Plant proteins ---- mRNA cap guanine-N7 methyltransferase 1 Source.30: DFBPPR2767 ---- Plant proteins ---- Diacylglycerol O-acyltransferase 1-2 Source.31: DFBPPR2773 ---- Plant proteins ---- Tripeptidyl-peptidase 2 Source.32: DFBPPR2938 ---- Plant proteins ---- Kinesin-like protein KIN-10A Source.33: DFBPPR2971 ---- Plant proteins ---- COBRA-like protein 3 Source.34: DFBPPR2972 ---- Plant proteins ---- Probable potassium transporter 14 Source.35: DFBPPR3115 ---- Plant proteins ---- Nucleosome assembly protein 1;1 Source.36: DFBPPR3116 ---- Plant proteins ---- Nucleosome assembly protein 1;2 Source.37: DFBPPR3154 ---- Plant proteins ---- Endoglucanase 7 Source.38: DFBPPR3155 ---- Plant proteins ---- Acyl transferase 1 Source.39: DFBPPR3186 ---- Plant proteins ---- Endoglucanase 10 Source.40: DFBPPR3243 ---- Plant proteins ---- Endoglucanase 21 Source.41: DFBPPR3248 ---- Plant proteins ---- Endoglucanase 16 Source.42: DFBPPR3255 ---- Plant proteins ---- COBRA-like protein 6 Source.43: DFBPPR3448 ---- Plant proteins ---- Endoglucanase 22 Source.44: DFBPPR3511 ---- Plant proteins ---- Kinesin-like protein KIN-14N Source.45: DFBPPR3520 ---- Plant proteins ---- COBRA-like protein 1 Source.46: DFBPPR3553 ---- Plant proteins ---- Probable auxin efflux carrier component 8 Source.47: DFBPPR3624 ---- Plant proteins ---- RNA pseudouridine synthase 4, mitochondrial Source.48: DFBPPR3652 ---- Plant proteins ---- Nucleosome assembly protein 1;3 Source.49: DFBPPR3775 ---- Plant proteins ---- Kinesin-like protein KIN-14G Source.50: DFBPPR3887 ---- Plant proteins ---- Endoglucanase 8 Source.51: DFBPPR3895 ---- Plant proteins ---- COBRA-like protein 2 Source.52: DFBPPR3926 ---- Plant proteins ---- Probable potassium transporter 13 Source.53: DFBPPR3966 ---- Plant proteins ---- Probable trehalose-phosphate phosphatase 7 Source.54: DFBPPR4003 ---- Plant proteins ---- Probable trehalose-phosphate phosphatase 9 Source.55: DFBPPR4071 ---- Plant proteins ---- Probable trehalose-phosphate phosphatase 6 Source.56: DFBPPR4086 ---- Plant proteins ---- Endoglucanase 5 Source.57: DFBPPR4291 ---- Plant proteins ---- Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform Source.58: DFBPPR4294 ---- Plant proteins ---- Nucleosome assembly protein 1-like 4 Source.59: DFBPPR4313 ---- Plant proteins ---- ASC1-like protein 1 Source.60: DFBPPR4372 ---- Plant proteins ---- NAP1-related protein 2 Source.61: DFBPPR4373 ---- Plant proteins ---- COBRA-like protein 4 Source.62: DFBPPR4380 ---- Plant proteins ---- Sucrose synthase 6 Source.63: DFBPPR4390 ---- Plant proteins ---- Spermidine hydroxycinnamoyltransferase 2 Source.64: DFBPPR4487 ---- Plant proteins ---- Spermidine hydroxycinnamoyltransferase 1 Source.65: DFBPPR4733 ---- Plant proteins ---- B3 domain-containing protein Os07g0679700 Source.66: DFBPPR4795 ---- Plant proteins ---- B3 domain-containing protein Os02g0598200 Source.67: DFBPPR5043 ---- Plant proteins ---- Flap endonuclease 1 Source.68: DFBPPR5049 ---- Plant proteins ---- Inducible nitrate reductase [NADH] 1 Source.69: DFBPPR5074 ---- Plant proteins ---- Phytochrome B Source.70: DFBPPR5172 ---- Plant proteins ---- NAD(P)H-quinone oxidoreductase chain 4, chloroplastic Source.71: DFBPPR5184 ---- Plant proteins ---- Omega-6 fatty acid desaturase, endoplasmic reticulum isozyme 2 Source.72: DFBPPR5379 ---- Plant proteins ---- (E)-beta-farnesene synthase Source.73: DFBPPR5386 ---- Plant proteins ---- (S)-beta-macrocarpene synthase Source.74: DFBPPR5388 ---- Plant proteins ---- (S)-beta-macrocarpene synthase Source.75: DFBPPR5408 ---- Plant proteins ---- 7-epi-sesquithujene synthase Source.76: DFBPPR5409 ---- Plant proteins ---- Sesquithujene synthase A Source.77: DFBPPR5542 ---- Plant proteins ---- Inactive sesquithujene synthase Source.78: DFBPPR5585 ---- Plant proteins ---- Tubulin gamma-2 chain Source.79: DFBPPR5592 ---- Plant proteins ---- Tubulin gamma-1 chain Source.80: DFBPPR5598 ---- Plant proteins ---- Trehalose 6-phosphate phosphatase RA3 Source.81: DFBPPR5603 ---- Plant proteins ---- Tubulin gamma-3 chain Source.82: DFBPPR5653 ---- Plant proteins ---- Inosine triphosphate pyrophosphatase Source.83: DFBPPR5698 ---- Plant proteins ---- Phytochrome A Source.84: DFBPPR5798 ---- Plant proteins ---- Inactive sesquithujene synthase B Source.85: DFBPPR5801 ---- Plant proteins ---- Inactive 7-epi-sesquithujene synthase Source.86: DFBPPR6227 ---- Plant proteins ---- Gibberellin 3-beta-dioxygenase 1 Source.87: DFBPPR7215 ---- Plant proteins ---- Aldose reductase Source.88: DFBPPR7317 ---- Plant proteins ---- Horcolin Source.89: DFBPPR7632 ---- Milk proteins ---- Receptor tyrosine-protein kinase erbB-4 Source.90: DFBPPR7661 ---- Milk proteins ---- IgG receptor FcRn large subunit p51 Source.91: DFBPPR8190 ---- Plant proteins ---- Acyl-coenzyme A oxidase, peroxisomal Source.92: DFBPPR15968 ---- Animal proteins ---- T-cell surface glycoprotein CD3 epsilon chain Source.93: DFBPPR15970 ---- Animal proteins ---- Aminopeptidase N Source.94: DFBPPR16053 ---- Animal proteins ---- Glyceraldehyde-3-phosphate dehydrogenase Source.95: DFBPPR16058 ---- Animal proteins ---- Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 Source.96: DFBPPR16063 ---- Animal proteins ---- Receptor tyrosine-protein kinase erbB-2 Source.97: DFBPPR16127 ---- Animal proteins ---- Tyrosine-protein kinase Fer Source.98: DFBPPR16158 ---- Animal proteins ---- Tyrosine-protein kinase Yes Source.99: DFBPPR16197 ---- Animal proteins ---- Cytochrome c oxidase subunit 1 Source.100: DFBPPR16321 ---- Animal proteins ---- Aggrecan core protein Source.101: DFBPPR16342 ---- Animal proteins ---- cGMP-gated cation channel alpha-1 Source.102: DFBPPR16343 ---- Animal proteins ---- cGMP-gated cation channel alpha-1 Source.103: DFBPPR16567 ---- Animal proteins ---- Oxygen-regulated protein 1 Source.104: DFBPPR16590 ---- Animal proteins ---- Arylsulfatase K Source.105: DFBPPR16620 ---- Animal proteins ---- Angiopoietin-1 Source.106: DFBPPR16731 ---- Animal proteins ---- Beta-defensin 110 Source.107: DFBPPR16732 ---- Animal proteins ---- HORMA domain-containing protein 2 Source.108: DFBPPR16762 ---- Animal proteins ---- Glyceraldehyde-3-phosphate dehydrogenase Source.109: DFBPPR16817 ---- Animal proteins ---- Cytochrome c oxidase subunit 1 Source.110: DFBPPR16959 ---- Animal proteins ---- Steroid 17-alpha-hydroxylase/17,20 lyase Source.111: DFBPPR16973 ---- Animal proteins ---- Fatty acid synthase Source.112: DFBPPR16987 ---- Animal proteins ---- Aggrecan core protein Source.113: DFBPPR17063 ---- Animal proteins ---- Lysophospholipid acyltransferase 5 Source.114: DFBPPR17099 ---- Animal proteins ---- cGMP-gated cation channel alpha-1 Source.115: DFBPPR17136 ---- Animal proteins ---- Tyrosine-protein kinase Fyn Source.116: DFBPPR17168 ---- Animal proteins ---- Angiopoietin-1 Source.117: DFBPPR17263 ---- Animal proteins ---- E3 ubiquitin-protein ligase UHRF1 Source.118: DFBPPR17297 ---- Animal proteins ---- Glyceraldehyde-3-phosphate dehydrogenase Source.119: DFBPPR17298 ---- Animal proteins ---- Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 Source.120: DFBPPR17368 ---- Animal proteins ---- Peroxisomal acyl-coenzyme A oxidase 1 Source.121: DFBPPR17456 ---- Animal proteins ---- Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Source.122: DFBPPR17744 ---- Animal proteins ---- Protein argonaute-2 Source.123: DFBPPR17789 ---- Animal proteins ---- Secretory phospholipase A2 receptor Source.124: DFBPPR17804 ---- Animal proteins ---- Calpain-1 catalytic subunit Source.125: DFBPPR17887 ---- Animal proteins ---- Bifunctional purine biosynthesis protein ATIC Source.126: DFBPPR18049 ---- Animal proteins ---- Transcription factor Dp-1 Source.127: DFBPPR18073 ---- Animal proteins ---- Endoplasmic reticulum aminopeptidase 2 Source.128: DFBPPR18140 ---- Animal proteins ---- Semaphorin-3C Source.129: DFBPPR18167 ---- Animal proteins ---- Ubiquitin thioesterase ZRANB1 Source.130: DFBPPR18365 ---- Animal proteins ---- Glutamyl aminopeptidase Source.131: DFBPPR18388 ---- Animal proteins ---- Elongation factor Tu, mitochondrial Source.132: DFBPPR18389 ---- Animal proteins ---- Short transient receptor potential channel 6 Source.133: DFBPPR18498 ---- Animal proteins ---- Neutral cholesterol ester hydrolase 1 Source.134: DFBPPR18547 ---- Animal proteins ---- AP-2 complex subunit mu Source.135: DFBPPR18560 ---- Animal proteins ---- Rho-related GTP-binding protein RhoF Source.136: DFBPPR18608 ---- Animal proteins ---- ATP-dependent RNA helicase DHX30 Source.137: DFBPPR18646 ---- Animal proteins ---- Angiopoietin-2 Source.138: DFBPPR18749 ---- Animal proteins ---- Short transient receptor potential channel 4 Source.139: DFBPPR18949 ---- Animal proteins ---- Ubiquitin carboxyl-terminal hydrolase MINDY-2 Source.140: DFBPPR18966 ---- Animal proteins ---- Lupus La protein homolog Source.141: DFBPPR19193 ---- Animal proteins ---- Transmembrane 9 superfamily member 4 Source.142: DFBPPR19195 ---- Animal proteins ---- V-type proton ATPase 116 kDa subunit a2 Source.143: DFBPPR19368 ---- Animal proteins ---- Prion-like protein doppel Source.144: DFBPPR19375 ---- Animal proteins ---- ATPase family AAA domain-containing protein 1 Source.145: DFBPPR19473 ---- Animal proteins ---- Hyaluronan and proteoglycan link protein 1 Source.146: DFBPPR19550 ---- Animal proteins ---- Coatomer subunit zeta-1 Source.147: DFBPPR19728 ---- Animal proteins ---- THO complex subunit 7 homolog Source.148: DFBPPR19746 ---- Animal proteins ---- tRNA pseudouridine(38/39) synthase Source.149: DFBPPR19755 ---- Animal proteins ---- Mitochondrial dimethyladenosine transferase 1 Source.150: DFBPPR19911 ---- Animal proteins ---- Guided entry of tail-anchored proteins factor 1 Source.151: DFBPPR20047 ---- Animal proteins ---- Tumor necrosis factor receptor superfamily member 11B Source.152: DFBPPR20205 ---- Animal proteins ---- Methionyl-tRNA formyltransferase, mitochondrial Source.153: DFBPPR20240 ---- Animal proteins ---- Leptin receptor gene-related protein Source.154: DFBPPR20405 ---- Animal proteins ---- Oxygen-regulated protein 1 Source.155: DFBPPR20421 ---- Animal proteins ---- U4/U6 small nuclear ribonucleoprotein Prp3 Source.156: DFBPPR20581 ---- Animal proteins ---- Membrane magnesium transporter 1 Source.157: DFBPPR20745 ---- Animal proteins ---- ETS-related transcription factor Elf-1 Source.158: DFBPPR20822 ---- Animal proteins ---- Ethanolamine-phosphate cytidylyltransferase Source.159: DFBPPR20850 ---- Animal proteins ---- Arylsulfatase K Source.160: DFBPPR20885 ---- Animal proteins ---- Zinc transporter ZIP3 Source.161: DFBPPR20970 ---- Animal proteins ---- ETS homologous factor Source.162: DFBPPR21078 ---- Animal proteins ---- Guanine nucleotide-binding protein-like 3-like protein Source.163: DFBPPR21464 ---- Animal proteins ---- Cleavage and polyadenylation specificity factor subunit 2 Source.164: DFBPPR21482 ---- Animal proteins ---- Glycosyltransferase 6 domain-containing protein 1 Source.165: DFBPPR21564 ---- Animal proteins ---- HORMA domain-containing protein 2 Source.166: DFBPPR21681 ---- Animal proteins ---- Protein FAM110A Source.167: DFBPPR21865 ---- Animal proteins ---- Transcription factor EC Source.168: DFBPPR21969 ---- Animal proteins ---- 1-aminocyclopropane-1-carboxylate synthase-like protein 1 Source.169: DFBPPR22066 ---- Animal proteins ---- Pyridoxal phosphate homeostasis protein Source.170: DFBPPR22069 ---- Animal proteins ---- Retrotransposon-like protein 1 Source.171: DFBPPR22152 ---- Animal proteins ---- Nucleolar protein 11 Source.172: DFBPPR22215 ---- Animal proteins ---- General transcription factor II-I repeat domain-containing protein 2 Source.173: DFBPPR22233 ---- Animal proteins ---- RNA exonuclease 5 Source.174: DFBPPR22288 ---- Animal proteins ---- Protein FAM110B Source.175: DFBPPR22581 ---- Animal proteins ---- UPF0690 protein C1orf52 homolog Source.176: DFBPPR22746 ---- Animal proteins ---- Uncharacterized protein C1orf146 homolog Source.177: DFBPPR8551 ---- Animal proteins ---- Aminopeptidase N Source.178: DFBPPR8590 ---- Animal proteins ---- Phospholipid hydroperoxide glutathione peroxidase Source.179: DFBPPR8663 ---- Animal proteins ---- Glyceraldehyde-3-phosphate dehydrogenase Source.180: DFBPPR8686 ---- Animal proteins ---- NAD(+) hydrolase SARM1 Source.181: DFBPPR8710 ---- Animal proteins ---- Leptin receptor Source.182: DFBPPR8742 ---- Animal proteins ---- Low-density lipoprotein receptor-related protein 2 Source.183: DFBPPR8752 ---- Animal proteins ---- Tyrosine-protein kinase Fyn Source.184: DFBPPR9079 ---- Animal proteins ---- Prolactin receptor Source.185: DFBPPR9112 ---- Animal proteins ---- Calcium-activated chloride channel regulator 1 Source.186: DFBPPR9169 ---- Animal proteins ---- Aggrecan core protein Source.187: DFBPPR9344 ---- Animal proteins ---- Desmoglein-1 Source.188: DFBPPR9422 ---- Animal proteins ---- C-C motif chemokine 25 Source.189: DFBPPR9504 ---- Animal proteins ---- Angiopoietin-2 Source.190: DFBPPR9531 ---- Animal proteins ---- Leptin receptor gene-related protein Source.191: DFBPPR9603 ---- Animal proteins ---- Hyaluronan and proteoglycan link protein 1 Source.192: DFBPPR9699 ---- Animal proteins ---- Angiopoietin-1 Source.193: DFBPPR9956 ---- Animal proteins ---- Fatty acid synthase Source.194: DFBPPR9982 ---- Animal proteins ---- Glyceraldehyde-3-phosphate dehydrogenase Source.195: DFBPPR9986 ---- Animal proteins ---- Aggrecan core protein Source.196: DFBPPR10013 ---- Animal proteins ---- Proto-oncogene tyrosine-protein kinase Src Source.197: DFBPPR10048 ---- Animal proteins ---- Tyrosine-protein kinase Yes Source.198: DFBPPR10052 ---- Animal proteins ---- Protein Wnt-11 Source.199: DFBPPR10058 ---- Animal proteins ---- Prospero homeobox protein 1 Source.200: DFBPPR10119 ---- Animal proteins ---- Down syndrome cell adhesion molecule homolog Source.201: DFBPPR10128 ---- Animal proteins ---- Focal adhesion kinase 1 Source.202: DFBPPR10194 ---- Animal proteins ---- Proto-oncogene tyrosine-protein kinase Yrk Source.203: DFBPPR10232 ---- Animal proteins ---- Neuronal acetylcholine receptor subunit alpha-4 Source.204: DFBPPR10255 ---- Animal proteins ---- Tyrosine-protein kinase Fyn Source.205: DFBPPR10347 ---- Animal proteins ---- Proto-oncogene tyrosine-protein kinase LCK Source.206: DFBPPR10355 ---- Animal proteins ---- Down syndrome cell adhesion molecule-like protein 1 homolog Source.207: DFBPPR10411 ---- Animal proteins ---- DNA-dependent protein kinase catalytic subunit Source.208: DFBPPR10447 ---- Animal proteins ---- Plastin-1 Source.209: DFBPPR10461 ---- Animal proteins ---- Cytochrome c oxidase subunit 1 Source.210: DFBPPR10500 ---- Animal proteins ---- Casein kinase I isoform epsilon Source.211: DFBPPR10576 ---- Animal proteins ---- Inosine triphosphate pyrophosphatase Source.212: DFBPPR10630 ---- Animal proteins ---- Contactin-2 Source.213: DFBPPR10729 ---- Animal proteins ---- Versican core protein Source.214: DFBPPR10768 ---- Animal proteins ---- Actin-histidine N-methyltransferase Source.215: DFBPPR10872 ---- Animal proteins ---- Inactive tyrosine-protein kinase 7 Source.216: DFBPPR10931 ---- Animal proteins ---- Nuclear receptor subfamily 2 group E member 1 Source.217: DFBPPR10941 ---- Animal proteins ---- Chromodomain-helicase-DNA-binding protein 1 Source.218: DFBPPR10963 ---- Animal proteins ---- Semaphorin-3C Source.219: DFBPPR11026 ---- Animal proteins ---- AP-2 complex subunit mu Source.220: DFBPPR11201 ---- Animal proteins ---- ATP-dependent RNA helicase DHX30 Source.221: DFBPPR11202 ---- Animal proteins ---- Myosin-binding protein C, fast-type Source.222: DFBPPR11203 ---- Animal proteins ---- Cyclic nucleotide-gated channel rod photoreceptor subunit alpha Source.223: DFBPPR11270 ---- Animal proteins ---- Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Source.224: DFBPPR11290 ---- Animal proteins ---- Cyclic nucleotide-gated channel cone photoreceptor subunit alpha Source.225: DFBPPR11326 ---- Animal proteins ---- P2Y purinoceptor 8 Source.226: DFBPPR11431 ---- Animal proteins ---- Putative glycerol kinase 5 Source.227: DFBPPR11556 ---- Animal proteins ---- Leptin receptor gene-related protein Source.228: DFBPPR11632 ---- Animal proteins ---- Ubiquitin-like domain-containing CTD phosphatase 1 Source.229: DFBPPR11808 ---- Animal proteins ---- U4/U6 small nuclear ribonucleoprotein Prp3 Source.230: DFBPPR11817 ---- Animal proteins ---- Meiosis regulator and mRNA stability factor 1 Source.231: DFBPPR12067 ---- Animal proteins ---- Transcription factor EC Source.232: DFBPPR12145 ---- Animal proteins ---- p21-activated protein kinase-interacting protein 1-like Source.233: DFBPPR12214 ---- Animal proteins ---- Nucleolar protein 11 Source.234: DFBPPR12287 ---- Animal proteins ---- Glyceraldehyde-3-phosphate dehydrogenase Source.235: DFBPPR12374 ---- Animal proteins ---- Sortilin-related receptor Source.236: DFBPPR12434 ---- Animal proteins ---- Aminopeptidase N Source.237: DFBPPR12440 ---- Animal proteins ---- Protein argonaute-2 Source.238: DFBPPR12444 ---- Animal proteins ---- C->U-editing enzyme APOBEC-1 Source.239: DFBPPR12550 ---- Animal proteins ---- Cytochrome c oxidase subunit 1 Source.240: DFBPPR12582 ---- Animal proteins ---- Cyclic nucleotide-gated olfactory channel Source.241: DFBPPR12947 ---- Animal proteins ---- Aggrecan core protein Source.242: DFBPPR13019 ---- Animal proteins ---- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform Source.243: DFBPPR13228 ---- Animal proteins ---- Cytochrome c oxidase subunit 1 Source.244: DFBPPR13356 ---- Animal proteins ---- Hyaluronan and proteoglycan link protein 1 Source.245: DFBPPR13429 ---- Animal proteins ---- Steroid 17-alpha-hydroxylase/17,20 lyase Source.246: DFBPPR13444 ---- Animal proteins ---- Cytochrome c oxidase subunit 1 Source.247: DFBPPR13553 ---- Animal proteins ---- Steroid 17-alpha-hydroxylase/17,20 lyase Source.248: DFBPPR13559 ---- Animal proteins ---- Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 Source.249: DFBPPR13589 ---- Animal proteins ---- Glyceraldehyde-3-phosphate dehydrogenase Source.250: DFBPPR13595 ---- Animal proteins ---- Cytochrome c oxidase subunit 1 Source.251: DFBPPR13677 ---- Animal proteins ---- Prolactin receptor Source.252: DFBPPR13796 ---- Animal proteins ---- Prion-like protein doppel Source.253: DFBPPR13988 ---- Animal proteins ---- Cytochrome c oxidase subunit 1 Source.254: DFBPPR14077 ---- Marine protein ---- Serotransferrin-1 Source.255: DFBPPR14079 ---- Marine protein ---- Cytochrome c oxidase subunit 1 Source.256: DFBPPR14080 ---- Marine protein ---- Serotransferrin-2 Source.257: DFBPPR14092 ---- Marine protein ---- Adenylosuccinate synthetase isozyme 1 B Source.258: DFBPPR14094 ---- Marine protein ---- Adenylosuccinate synthetase isozyme 1 C Source.259: DFBPPR14101 ---- Marine protein ---- Adenylosuccinate synthetase isozyme 1 A Source.260: DFBPPR14417 ---- Marine protein ---- Histidine--tRNA ligase, chloroplastic Source.261: DFBPPR14532 ---- Marine protein ---- Uncharacterized protein ORF621 Source.262: DFBPPR14568 ---- Marine protein ---- Cytochrome c oxidase subunit 1 Source.263: DFBPPR14879 ---- Microorganism protein ---- Pentafunctional AROM polypeptide Source.264: DFBPPR14938 ---- Microorganism protein ---- Inosine triphosphate pyrophosphatase Source.265: DFBPPR14945 ---- Microorganism protein ---- Decapping nuclease RAI1 Source.266: DFBPPR14961 ---- Microorganism protein ---- Alcohol dehydrogenase 1 Source.267: DFBPPR14980 ---- Microorganism protein ---- Ribonuclease T2-like Source.268: DFBPPR15029 ---- Microorganism protein ---- Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase Source.269: DFBPPR15044 ---- Microorganism protein ---- Alcohol dehydrogenase 4, mitochondrial Source.270: DFBPPR15092 ---- Microorganism protein ---- Alcohol dehydrogenase 3, mitochondrial Source.271: DFBPPR15098 ---- Microorganism protein ---- Deoxyhypusine hydroxylase Source.272: DFBPPR15162 ---- Microorganism protein ---- MFS-type transporter PUL3 Source.273: DFBPPR15186 ---- Microorganism protein ---- Alcohol dehydrogenase 2 Source.274: DFBPPR15238 ---- Microorganism protein ---- Pre-mRNA-splicing factor CLF1 Source.275: DFBPPR15242 ---- Microorganism protein ---- Golgi to ER traffic protein 2 Source.276: DFBPPR15266 ---- Microorganism protein ---- Phosphatidylethanolamine N-methyltransferase Source.277: DFBPPR15273 ---- Microorganism protein ---- 21S rRNA pseudouridine(2819) synthase Source.278: DFBPPR15487 ---- Microorganism protein ---- Restriction of telomere capping protein 1 Source.279: DFBPPR15540 ---- Microorganism protein ---- Probable intron-encoded endonuclease aI3 Source.280: DFBPPR15555 ---- Microorganism protein ---- Spindle pole body component 110 Source.281: DFBPPR15558 ---- Microorganism protein ---- Protein CFT1 Source.282: DFBPPR15592 ---- Microorganism protein ---- UDP-galactose transporter homolog 1 Source.283: DFBPPR15696 ---- Microorganism protein ---- pH-response regulator palI/RIM9 homolog 1 Source.284: DFBPPR15763 ---- Microorganism protein ---- ATPase expression protein 3 Source.285: DFBPPR15852 ---- Microorganism protein ---- Glyceraldehyde-3-phosphate dehydrogenase 1 Source.286: DFBPPR15881 ---- Microorganism protein ---- Glyceraldehyde-3-phosphate dehydrogenase Source.287: DFBPPR7771 ---- Plant protein ---- Inosine triphosphate pyrophosphatase Source.288: DFBPPR7776 ---- Plant protein ---- Beta-sesquiphellandrene synthase Source.289: DFBPPR7802 ---- Plant protein ---- Phytochrome B Source.290: DFBPPR7814 ---- Plant protein ---- Phytochrome a Source.291: DFBPPR7825 ---- Plant protein ---- Phytochrome C Source.292: DFBPPR8065 ---- Plant protein ---- NAD(P)H-quinone oxidoreductase chain 4, chloroplastic Source.293: DFBPPR8295 ---- Plant protein ---- Probable phospholipid hydroperoxide glutathione peroxidase
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

Antihypertensive activity

Table 1. Inhibitory activities for antihypertensive activities of peptides following intravenous administration in SHR
Peptide	Dose (mg/kg)	Antihypertensive activity (△mmHg, i.v.*)	Time
IKW	10	-50	4 h
	60	-17
* Decrease of systolic blood pressure after intravenous administration.

Specific target protein(s)

N.D

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Bitter taste ^prediction

SMILES

N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)O

Preparation method

Mode of preparation	Enzymatic hydrolysis
Enzyme(s)/starter culture	Chicken muscle was hydrolyzed with thermolysin.

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	Non-Toxin
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

DFBP

[D1]	DFBPACEI0090, DFBPACEI0691, DFBPACEI1644
[D2]	DFBPMUFU0042

[D3]

[D4]

[D5]

[D6]

Reference(s)

Primary literature	Iroyukifujita, H., Eiichiyokoyama, K., Yoshikawa, M. Classification and Antihypertensive Activity of Angiotensin I-Converting Enzyme Inhibitory Peptides Derived from Food Proteins. Journal of Food Science. 2000, 65, 564-9. DOI: 10.1111/j.1365-2621.2000.tb16049.x
Other literature(s)	[1] Rosales-Mendoza, S., et al., Engineering production of antihypertensive peptides in plants. Plant Cell Tissue and Organ Culture, 2013. 112(2): p. 159-169. [2] Martinez-Maqueda, D., et al., Antihypertensive peptides from food proteins: a review. Food Funct, 2012. 3(4): p. 350-361.
PubDate	2000