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List of peptide properties
DFBP ID - DFBPANOX0005(Antioxidative peptide)
DFBP ID DFBPANOX0005
Peptide sequence VIPAGYP
Type Native peptide
Peptide/Function name Antioxidative peptide, P5
Function-activity relationship
Main bioactivity Antioxidative activity
Otheir bioactivity N.D
Calculated physicochemical properties
Three-letter amino acid Val-Ile-Pro-Ala-Gly-Tyr-Pro
Single-letter amino acid VIPAGYP
Peptide length 7
Peptide mass
Experimental mass Theoretical mass
715.4 Da 715.84 Da c
Net charge 0.00 c
Isoelectric point (pI) 5.92 c
IC50 N.D
pIC50 N.D
GRAVY 0.8000 c
Hydrophilic residue ratio 85.71% c
Peptide calculator
To calculate the physicochemical properties of bioactive peptide.
Peptide source & Food-borne protein(s) search
Classification Plant
Organism/Source Soybean protein
Precursor protein β-Conglycinin (7S protein)
Residue position N.D
Precursor protein(s) search
Link-research
There are no literature reports on the discovery of this sequence in other food-source proteins.
Biological/Functional activity & target protein
Antioxidative activity

This peptide yielded antioxidative activity against the peroxidation of linoleic acid in an aqueous system at pH 7.0. The antioxidative activity was measured with 49 μg of P5 and the peptide concentrations ranged from 3.3 × 10-7 to 4.5 × 10-5 M, in which range the antioxidative activity was dose dependent and no prooxidative activity was observed (data not shown).

Specific target protein(s) N.D
Taste properties & Structure
Bitterness
Literature report N.D
Bitter prediction tools Bitter taste prediction
SMILES N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1[C@@]([H])(CCC1)C(=O)O
Preparation method
Mode of preparation Enzymatic hydrolysis
Enzyme(s)/starter culture

Peptide obtained by hydrolysis of a soybean β-conglycinin (7S protein) by use of protease S.

Stability & Cytotoxicity
Peptide stability
Literature report: N.D
EHP-Tool: Enzymatic Hydrolysis Prediction Tool (EHP-Tool)
Peptide cytotoxicity
Literature report: N.D
Prediction: ToxinPred
Additional information
Additional information N.D
Database cross-references
BIOPEP-UWM [D1] 3808
APD [D2] -
BioPepDB [D3] -
MBPDB [D4] -
Reference(s)
Primary literature Chen, H.-M., Muramoto, K., Yamauchi, F. Structural Analysis of Antioxidative Peptides from Soybean .beta.-Conglycinin. Journal of Agricultural and Food Chemistry. 1995, 43, 574-8.
Other literature(s)

[1] Chen H M, Muramoto K, Yamauchi F, et al. Antioxidant Activity of Designed Peptides Based on the Antioxidative Peptide Isolated from Digests of a Soybean Protein[J]. Journal of Agricultural & Food Chemistry, 1996, 44(9):2619-2623.
[2] Huaming Chen †, Koji Muramoto , †, Fumio Yamauchi †, et al. Antioxidative Properties of Histidine-Containing Peptides Designed from Peptide Fragments Found in the Digests of a Soybean Protein.[J]. Journal of Agricultural & Food Chemistry, 1998, 46(1):49.

PubDate 1995
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