Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPANOX0138(Antioxidative peptide)

DFBP ID	DFBPANOX0138
Peptide sequence	LQGMP
Type	Native peptide
Peptide/Function name	Antioxidative peptide

Function-activity relationship

Main bioactivity	Antioxidative activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

Leu-Gln-Gly-Met-Pro

Single-letter amino acid

LQGMP

Peptide length

Peptide mass

Experimental mass	Theoretical mass
560.3 Da	544.67 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

5.97 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

0.0400^c

Hydrophilic residue ratio

80%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Animal
Organism/Source	Pig
Precursor protein	Porcine sking collagen hydrolysates
Residue position	f(123-127)
Precursor protein(s) search	Source.1: DFBPPR16048 ---- Animal proteins ---- Collagen alpha-1(I) chain Source.2: DFBPPR16842 ---- Animal proteins ---- Collagen alpha-1(II) chain Source.3: DFBPPR17360 ---- Animal proteins ---- Collagen alpha-1(I) chain Source.4: DFBPPR18537 ---- Animal proteins ---- Collagen alpha-1(III) chain Source.5: DFBPPR9985 ---- Animal proteins ---- Collagen alpha-1(II) chain Source.6: DFBPPR10470 ---- Animal proteins ---- Collagen alpha-1(III) chain Source.7: DFBPPR14569 ---- Marine protein ---- Collagen alpha-2(I) chain
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

Antioxidative activity	The peptide exhibited antioxidant activities on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, metal chelating and in a linoleic acid peroxidation system induced by Fe²⁺ (data not shown).
Specific target protein(s)	N.D

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Non-bitter taste ^prediction

SMILES

N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)NCC(=O)N[C@@]([H])(CCSC)C(=O)N1[C@@]([H])(CCC1)C(=O)O

Preparation method

Mode of preparation	Enzymatic hydrolysis
Enzyme(s)/starter culture	Hydrolyzed with pepsin and cocktail mixture of protease bovine pancreas, protease Streptomyces and protease Bacillus spp.

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

It is feasible to produce natural antioxidants from porcine collagen by enzymatic hydrolysis.

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Li, B., Chen, F., Wang, X., Ji, B., Wu, Y. Isolation and identification of antioxidative peptides from porcine collagen hydrolysate by consecutive chromatography and electrospray ionization–mass spectrometry. Food Chem. 2007, 102, 1135-43. DOI: 10.1016/j.foodchem.2006.07.002
Other literature(s)	No data
PubDate	2007