Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPANOX0205(Antioxidative peptide)

DFBP ID	DFBPANOX0205
Peptide sequence	YGYTGA
Type	Native peptide
Peptide/Function name	Antioxidative peptide, 23-7

Function-activity relationship

Main bioactivity	Antioxidative activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

Tyr-Gly-Tyr-Thr-Gly-Ala

Single-letter amino acid

YGYTGA

Peptide length

Peptide mass

Experimental mass	Theoretical mass
631.35 Da	630.65 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

5.87 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

-0.3833^c

Hydrophilic residue ratio

50%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Human
Organism/Source	Human milk
Precursor protein	Proteins
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR7596 ---- Milk proteins ---- Lactotransferrin Source.2: DFBPPR7658 ---- Milk proteins ---- Lactotransferrin Source.3: DFBPPR7669 ---- Milk proteins ---- Lactotransferrin Source.4: DFBPPR7683 ---- Milk proteins ---- Lactotransferrin Source.5: DFBPPR7713 ---- Milk proteins ---- Lactotransferrin Source.6: DFBPPR8500 ---- Milk proteins ---- Lactotransferrin Source.7: DFBPPR18952 ---- Animal proteins ---- Serotransferrin Source.8: DFBPPR9015 ---- Animal proteins ---- Serotransferrin Source.9: DFBPPR11757 ---- Animal proteins ---- RNA-binding protein 38 Source.10: DFBPPR12251 ---- Animal proteins ---- Serotransferrin Source.11: DFBPPR13263 ---- Animal proteins ---- Serotransferrin Source.12: DFBPPR14077 ---- Marine protein ---- Serotransferrin-1 Source.13: DFBPPR14080 ---- Marine protein ---- Serotransferrin-2
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

Antioxidative activity	The peptide YGYTGA showed high peroxyl radical scavenging activity with the ORAC value of 5169 μM TE/mM.
Specific target protein(s)	N.D

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Non-bitter taste ^prediction

SMILES

N[C@@]([H])(Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)O

Preparation method

Mode of preparation	Enzymatic hydrolysis
Enzyme(s)/starter culture	Hydrolyzed with Pepsin P-7000 and Pancreatin P1750.

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Tsopmo, A., Romanowski, A., Banda, L., Lavoie, J.C., Jenssen, H., Friel, J.K. Novel anti-oxidative peptides from enzymatic digestion of human milk. Food Chem. 2011, 126, 1138-43. DOI: 10.1016/j.foodchem.2010.11.146
Other literature(s)	No data
PubDate	2011