Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPDPIV0164(DPP IV-inhibitory peptide)

DFBP ID	DFBPDPIV0164
Peptide sequence	GPGG
Type	Native peptide
Peptide/Function name	DPP IV-inhibitory peptide, Anti-diabetic peptide

Function-activity relationship

Main bioactivity	DPP-IV inhibitory activity
Otheir bioactivity	Antithrombotic activity ^[D1], Multifunctional activity ^[D2]

Calculated physicochemical properties

Three-letter amino acid

Gly-Pro-Gly-Gly

Single-letter amino acid

GPGG

Peptide length

Peptide mass

Experimental mass	Theoretical mass
N.D	286.29 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

5.97 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

-0.7000^c

Hydrophilic residue ratio

100%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Plant
Organism/Source	Oryza sativa subsp. japonica (Rice)
Precursor protein	Seed allergenic protein RAG1
Residue position	f(145-148)
Precursor protein(s) search	Source.1: DFBPPR0887 ---- Plant proteins ---- Protein NARROW LEAF 1 Source.2: DFBPPR0888 ---- Plant proteins ---- Protein NARROW LEAF 1 Source.3: DFBPPR1044 ---- Plant proteins ---- Neutral ceramidase Source.4: DFBPPR1123 ---- Plant proteins ---- Allene oxide synthase 1, chloroplastic Source.5: DFBPPR1228 ---- Plant proteins ---- Isoamylase 2, chloroplastic Source.6: DFBPPR1291 ---- Plant proteins ---- 6-phosphogluconate dehydrogenase, decarboxylating 2, chloroplastic Source.7: DFBPPR1327 ---- Plant proteins ---- Heat stress transcription factor A-4d Source.8: DFBPPR1383 ---- Plant proteins ---- Protein rough sheath 2 homolog Source.9: DFBPPR1386 ---- Plant proteins ---- Transcription factor LATE FLOWERING Source.10: DFBPPR1447 ---- Plant proteins ---- Two-component response regulator-like PRR37 Source.11: DFBPPR1470 ---- Plant proteins ---- Alpha-galactosidase Source.12: DFBPPR1486 ---- Plant proteins ---- Probable transcription factor RL9 Source.13: DFBPPR1528 ---- Plant proteins ---- Cyclin-dependent kinase C-2 Source.14: DFBPPR1574 ---- Plant proteins ---- ATP-dependent zinc metalloprotease FTSH 1, chloroplastic Source.15: DFBPPR1660 ---- Plant proteins ---- Magnesium-chelatase subunit ChlH, chloroplastic Source.16: DFBPPR1721 ---- Plant proteins ---- Cyclin-dependent kinase C-1 Source.17: DFBPPR1756 ---- Plant proteins ---- Soluble starch synthase 2-1, chloroplastic/amyloplastic Source.18: DFBPPR1911 ---- Plant proteins ---- Heat stress transcription factor A-6a Source.19: DFBPPR2074 ---- Plant proteins ---- Potassium transporter 7 Source.20: DFBPPR2091 ---- Plant proteins ---- Cellulose synthase-like protein D3 Source.21: DFBPPR2098 ---- Plant proteins ---- DNA replication licensing factor MCM5 Source.22: DFBPPR2135 ---- Plant proteins ---- Putative DNA ligase 4 Source.23: DFBPPR2248 ---- Plant proteins ---- Membrane steroid-binding protein 1 Source.24: DFBPPR2253 ---- Plant proteins ---- Probable methylenetetrahydrofolate reductase Source.25: DFBPPR2297 ---- Plant proteins ---- Probable LL-diaminopimelate aminotransferase, chloroplastic Source.26: DFBPPR2304 ---- Plant proteins ---- Photosystem II CP43 reaction center protein Source.27: DFBPPR2347 ---- Plant proteins ---- Cellulose synthase-like protein E2 Source.28: DFBPPR2353 ---- Plant proteins ---- Expansin-B12 Source.29: DFBPPR2371 ---- Plant proteins ---- Seed allergenic protein RAG1 Source.30: DFBPPR2649 ---- Plant proteins ---- Nuclear transcription factor Y subunit B-8 Source.31: DFBPPR2652 ---- Plant proteins ---- Probable tRNA-splicing endonuclease subunit Sen2 Source.32: DFBPPR2687 ---- Plant proteins ---- Protein AMEIOTIC 1 homolog Source.33: DFBPPR2737 ---- Plant proteins ---- Putative beta-glucosidase 9 Source.34: DFBPPR2856 ---- Plant proteins ---- DNA-directed RNA polymerase subunit beta Source.35: DFBPPR2895 ---- Plant proteins ---- Serine/arginine-rich splicing factor RSZ21 Source.36: DFBPPR2899 ---- Plant proteins ---- Transcription factor PCF7 Source.37: DFBPPR2985 ---- Plant proteins ---- Coatomer subunit delta-3 Source.38: DFBPPR3086 ---- Plant proteins ---- Homeobox-leucine zipper protein HOX33 Source.39: DFBPPR3239 ---- Plant proteins ---- Pyruvate dehydrogenase E1 component subunit beta-4, chloroplastic Source.40: DFBPPR3309 ---- Plant proteins ---- Membrane steroid-binding protein 2 Source.41: DFBPPR3453 ---- Plant proteins ---- Probable protein phosphatase 2C 44 Source.42: DFBPPR3491 ---- Plant proteins ---- Aminotransferase ALD1 homolog Source.43: DFBPPR3640 ---- Plant proteins ---- Dof zinc finger protein 1 Source.44: DFBPPR3817 ---- Plant proteins ---- Beta-galactosidase 4 Source.45: DFBPPR3907 ---- Plant proteins ---- Cyclin-A1-4 Source.46: DFBPPR3954 ---- Plant proteins ---- Pyruvate dehydrogenase E1 component subunit beta-3, chloroplastic Source.47: DFBPPR4105 ---- Plant proteins ---- Squamosa promoter-binding-like protein 15 Source.48: DFBPPR4176 ---- Plant proteins ---- 5'-adenylylsulfate reductase-like 3 Source.49: DFBPPR4218 ---- Plant proteins ---- Glycine-rich cell wall structural protein 2 Source.50: DFBPPR4256 ---- Plant proteins ---- Copper transporter 4 Source.51: DFBPPR4259 ---- Plant proteins ---- Probable inactive methyltransferase Os04g0175900 Source.52: DFBPPR4270 ---- Plant proteins ---- CASP-like protein Os03g0196400 Source.53: DFBPPR4303 ---- Plant proteins ---- Zinc finger CCCH domain-containing protein 17 Source.54: DFBPPR4314 ---- Plant proteins ---- Hydroxycinnamoyltransferase 1 Source.55: DFBPPR4469 ---- Plant proteins ---- Protein argonaute 11 Source.56: DFBPPR4499 ---- Plant proteins ---- Hydroxycinnamoyltransferase 2 Source.57: DFBPPR4538 ---- Plant proteins ---- Protein argonaute 2 Source.58: DFBPPR4542 ---- Plant proteins ---- Zinc finger CCCH domain-containing protein 59 Source.59: DFBPPR4549 ---- Plant proteins ---- Ammonium transporter 3 member 3 Source.60: DFBPPR4779 ---- Plant proteins ---- Zinc finger CCCH domain-containing protein 31 Source.61: DFBPPR4891 ---- Plant proteins ---- Isoamylase 1, chloroplastic Source.62: DFBPPR4999 ---- Plant proteins ---- Leghemoglobin reductase Source.63: DFBPPR5099 ---- Plant proteins ---- Metalloendoproteinase 1 Source.64: DFBPPR5123 ---- Plant proteins ---- Photosystem II CP43 reaction center protein Source.65: DFBPPR5150 ---- Plant proteins ---- Profilin-2 Source.66: DFBPPR5154 ---- Plant proteins ---- Profilin-1 Source.67: DFBPPR5200 ---- Plant proteins ---- DNA-directed RNA polymerase subunit beta Source.68: DFBPPR5239 ---- Plant proteins ---- Heat shock 70 kDa protein Source.69: DFBPPR5296 ---- Plant proteins ---- 18 kDa seed maturation protein Source.70: DFBPPR5437 ---- Plant proteins ---- Exopolygalacturonase Source.71: DFBPPR5527 ---- Plant proteins ---- Exopolygalacturonase Source.72: DFBPPR5528 ---- Plant proteins ---- Exopolygalacturonase Source.73: DFBPPR5547 ---- Plant proteins ---- Methylenetetrahydrofolate reductase 1 Source.74: DFBPPR5767 ---- Plant proteins ---- Teosinte glume architecture 1 Source.75: DFBPPR5788 ---- Plant proteins ---- Globulin-1 S allele Source.76: DFBPPR5797 ---- Plant proteins ---- DNA-directed RNA polymerase subunit beta Source.77: DFBPPR5803 ---- Plant proteins ---- Anthocyanidin 3-O-glucosyltransferase Source.78: DFBPPR5810 ---- Plant proteins ---- Anthocyanidin 3-O-glucosyltransferase Source.79: DFBPPR5860 ---- Plant proteins ---- Myb-related protein P Source.80: DFBPPR6010 ---- Plant proteins ---- Teosinte glume architecture 1 Source.81: DFBPPR6157 ---- Plant proteins ---- Ninja-family protein 5 Source.82: DFBPPR6211 ---- Plant proteins ---- Anthocyanidin 3-O-glucosyltransferase Source.83: DFBPPR6217 ---- Plant proteins ---- Dihydrolipoyl dehydrogenase, mitochondrial Source.84: DFBPPR6340 ---- Plant proteins ---- Photosystem II CP43 reaction center protein Source.85: DFBPPR6554 ---- Plant proteins ---- Retinoblastoma-related protein 1 Source.86: DFBPPR6555 ---- Plant proteins ---- Retinoblastoma-related protein 1 Source.87: DFBPPR6772 ---- Plant proteins ---- Photosystem II CP43 reaction center protein Source.88: DFBPPR6850 ---- Plant proteins ---- DNA-directed RNA polymerase subunit beta Source.89: DFBPPR6875 ---- Plant proteins ---- Eukaryotic translation initiation factor 4G Source.90: DFBPPR7105 ---- Plant proteins ---- Photosystem II CP43 reaction center protein Source.91: DFBPPR7221 ---- Plant proteins ---- DNA-directed RNA polymerase subunit beta Source.92: DFBPPR7272 ---- Plant proteins ---- Photosystem II 10 kDa polypeptide, chloroplastic Source.93: DFBPPR7628 ---- Milk proteins ---- Complement C4-A Source.94: DFBPPR8408 ---- Plant proteins ---- Profilin Source.95: DFBPPR8454 ---- Plant proteins ---- Photosystem II CP43 reaction center protein Source.96: DFBPPR15948 ---- Animal proteins ---- Homeobox protein MSX-2 Source.97: DFBPPR16005 ---- Animal proteins ---- Myc proto-oncogene protein Source.98: DFBPPR16050 ---- Animal proteins ---- Dual oxidase 1 Source.99: DFBPPR16076 ---- Animal proteins ---- Gap junction alpha-5 protein Source.100: DFBPPR16093 ---- Animal proteins ---- Menin Source.101: DFBPPR16161 ---- Animal proteins ---- Dihydrolipoyl dehydrogenase, mitochondrial Source.102: DFBPPR16185 ---- Animal proteins ---- Cytokine receptor common subunit gamma Source.103: DFBPPR16187 ---- Animal proteins ---- Dual serine/threonine and tyrosine protein kinase Source.104: DFBPPR16199 ---- Animal proteins ---- Potassium-transporting ATPase alpha chain 1 Source.105: DFBPPR16203 ---- Animal proteins ---- E3 ubiquitin-protein ligase RING1 Source.106: DFBPPR16221 ---- Animal proteins ---- Xylosyltransferase 2 Source.107: DFBPPR16224 ---- Animal proteins ---- Uromodulin Source.108: DFBPPR16235 ---- Animal proteins ---- Serum amyloid A protein Source.109: DFBPPR16243 ---- Animal proteins ---- Retinoic acid receptor RXR-beta Source.110: DFBPPR16252 ---- Animal proteins ---- Steroid hormone receptor ERR1 Source.111: DFBPPR16284 ---- Animal proteins ---- Collagen alpha-2(I) chain Source.112: DFBPPR16294 ---- Animal proteins ---- Signal peptidase complex subunit 2 Source.113: DFBPPR16309 ---- Animal proteins ---- Gastrin/cholecystokinin type B receptor Source.114: DFBPPR16324 ---- Animal proteins ---- NPC intracellular cholesterol transporter 2 Source.115: DFBPPR16474 ---- Animal proteins ---- Pinin Source.116: DFBPPR16518 ---- Animal proteins ---- Keratin, type II cytoskeletal 2 epidermal Source.117: DFBPPR16598 ---- Animal proteins ---- Keratin, type I cytoskeletal 9 Source.118: DFBPPR16612 ---- Animal proteins ---- T-box transcription factor TBX19 Source.119: DFBPPR16626 ---- Animal proteins ---- RING finger protein unkempt homolog Source.120: DFBPPR16668 ---- Animal proteins ---- Zinc finger and BTB domain-containing protein 22 Source.121: DFBPPR16720 ---- Animal proteins ---- Tudor domain-containing protein 5 Source.122: DFBPPR16726 ---- Animal proteins ---- Ral guanine nucleotide dissociation stimulator-like 2 Source.123: DFBPPR16872 ---- Animal proteins ---- Oxytocin-neurophysin 1 Source.124: DFBPPR16978 ---- Animal proteins ---- Enteropeptidase Source.125: DFBPPR17041 ---- Animal proteins ---- Protein kinase C gamma type Source.126: DFBPPR17057 ---- Animal proteins ---- Cation-independent mannose-6-phosphate receptor Source.127: DFBPPR17266 ---- Animal proteins ---- WASH complex subunit 1 Source.128: DFBPPR17292 ---- Animal proteins ---- COUP transcription factor 2 Source.129: DFBPPR17308 ---- Animal proteins ---- Homeobox protein MSX-2 Source.130: DFBPPR17353 ---- Animal proteins ---- Receptor-type tyrosine-protein phosphatase-like N Source.131: DFBPPR17377 ---- Animal proteins ---- Adenylate cyclase type 1 Source.132: DFBPPR17405 ---- Animal proteins ---- Transcription factor HES-1 Source.133: DFBPPR17444 ---- Animal proteins ---- Adhesion G protein-coupled receptor L1 Source.134: DFBPPR17450 ---- Animal proteins ---- Adhesion G protein-coupled receptor L3 Source.135: DFBPPR17471 ---- Animal proteins ---- Interstitial collagenase Source.136: DFBPPR17484 ---- Animal proteins ---- Histone H1.8 Source.137: DFBPPR17506 ---- Animal proteins ---- Vasopressin-neurophysin 2-copeptin Source.138: DFBPPR17533 ---- Animal proteins ---- Carboxypeptidase E Source.139: DFBPPR17614 ---- Animal proteins ---- E3 ubiquitin-protein ligase ARIH1 Source.140: DFBPPR17618 ---- Animal proteins ---- Synaptophysin Source.141: DFBPPR17626 ---- Animal proteins ---- Elastin Source.142: DFBPPR17717 ---- Animal proteins ---- Unconventional myosin-Ia Source.143: DFBPPR17782 ---- Animal proteins ---- Ras GTPase-activating protein-binding protein 1 Source.144: DFBPPR17902 ---- Animal proteins ---- PDZ and LIM domain protein 4 Source.145: DFBPPR17914 ---- Animal proteins ---- Glycerol-3-phosphate acyltransferase 1, mitochondrial Source.146: DFBPPR17930 ---- Animal proteins ---- Dual serine/threonine and tyrosine protein kinase Source.147: DFBPPR17994 ---- Animal proteins ---- Lysophospholipid acyltransferase 7 Source.148: DFBPPR18130 ---- Animal proteins ---- CCAAT/enhancer-binding protein alpha Source.149: DFBPPR18142 ---- Animal proteins ---- Protein CASC3 Source.150: DFBPPR18158 ---- Animal proteins ---- Coagulation factor XII Source.151: DFBPPR18173 ---- Animal proteins ---- Cytokine receptor common subunit gamma Source.152: DFBPPR18219 ---- Animal proteins ---- Hsp90 co-chaperone Cdc37 Source.153: DFBPPR18223 ---- Animal proteins ---- Exosome complex component RRP40 Source.154: DFBPPR18231 ---- Animal proteins ---- Transcription factor jun-B Source.155: DFBPPR18347 ---- Animal proteins ---- Nucleolar complex protein 2 homolog Source.156: DFBPPR18418 ---- Animal proteins ---- Cleavage and polyadenylation specificity factor subunit 6 Source.157: DFBPPR18435 ---- Animal proteins ---- Paraspeckle component 1 Source.158: DFBPPR18522 ---- Animal proteins ---- POU domain, class 5, transcription factor 1 Source.159: DFBPPR18537 ---- Animal proteins ---- Collagen alpha-1(III) chain Source.160: DFBPPR18549 ---- Animal proteins ---- Serum amyloid A protein Source.161: DFBPPR18550 ---- Animal proteins ---- Prostaglandin E2 receptor EP3 subtype Source.162: DFBPPR18563 ---- Animal proteins ---- Collectin-43 Source.163: DFBPPR18586 ---- Animal proteins ---- Heterogeneous nuclear ribonucleoproteins A2/B1 Source.164: DFBPPR18608 ---- Animal proteins ---- ATP-dependent RNA helicase DHX30 Source.165: DFBPPR18617 ---- Animal proteins ---- Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial Source.166: DFBPPR18648 ---- Animal proteins ---- Proteasomal ubiquitin receptor ADRM1 Source.167: DFBPPR18826 ---- Animal proteins ---- Growth/differentiation factor 6 Source.168: DFBPPR18851 ---- Animal proteins ---- Neurogranin Source.169: DFBPPR18865 ---- Animal proteins ---- Collagen alpha-1(XI) chain Source.170: DFBPPR18879 ---- Animal proteins ---- Corrinoid adenosyltransferase Source.171: DFBPPR18961 ---- Animal proteins ---- Transmembrane protein 184A Source.172: DFBPPR18997 ---- Animal proteins ---- Striatin-3 Source.173: DFBPPR19033 ---- Animal proteins ---- Collagen alpha-2(XI) chain Source.174: DFBPPR19104 ---- Animal proteins ---- Inter-alpha-trypsin inhibitor heavy chain H4 Source.175: DFBPPR19152 ---- Animal proteins ---- E3 ubiquitin-protein ligase RNF186 Source.176: DFBPPR19207 ---- Animal proteins ---- Putative sodium-coupled neutral amino acid transporter 7 Source.177: DFBPPR19235 ---- Animal proteins ---- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 Source.178: DFBPPR19259 ---- Animal proteins ---- Protein transport protein Sec16B Source.179: DFBPPR19309 ---- Animal proteins ---- Cadherin-related family member 1 Source.180: DFBPPR19332 ---- Animal proteins ---- Collagen alpha-1(XII) chain Source.181: DFBPPR19397 ---- Animal proteins ---- Gap junction delta-2 protein Source.182: DFBPPR19449 ---- Animal proteins ---- SCO-spondin Source.183: DFBPPR19453 ---- Animal proteins ---- Peptidyl-tRNA hydrolase ICT1, mitochondrial Source.184: DFBPPR19462 ---- Animal proteins ---- Intercellular adhesion molecule 1 Source.185: DFBPPR19467 ---- Animal proteins ---- Integral membrane protein GPR137 Source.186: DFBPPR19515 ---- Animal proteins ---- Protein strawberry notch homolog 2 Source.187: DFBPPR19531 ---- Animal proteins ---- Interferon omega-1 Source.188: DFBPPR19570 ---- Animal proteins ---- Transmembrane protein 8B Source.189: DFBPPR19602 ---- Animal proteins ---- Dynactin subunit 3 Source.190: DFBPPR19629 ---- Animal proteins ---- Pro-FMRFamide-related neuropeptide FF Source.191: DFBPPR19720 ---- Animal proteins ---- RILP-like protein 2 Source.192: DFBPPR19744 ---- Animal proteins ---- Placental prolactin-related protein 2 Source.193: DFBPPR19755 ---- Animal proteins ---- Mitochondrial dimethyladenosine transferase 1 Source.194: DFBPPR19838 ---- Animal proteins ---- Transcription factor GATA-5 Source.195: DFBPPR19853 ---- Animal proteins ---- Heat shock-related 70 kDa protein 2 Source.196: DFBPPR19861 ---- Animal proteins ---- Phospholipid phosphatase-related protein type 2 Source.197: DFBPPR19866 ---- Animal proteins ---- Actin-related protein 8 Source.198: DFBPPR19948 ---- Animal proteins ---- Tensin-4 Source.199: DFBPPR19999 ---- Animal proteins ---- Cell death-inducing p53-target protein 1 Source.200: DFBPPR20068 ---- Animal proteins ---- H2.0-like homeobox protein Source.201: DFBPPR20128 ---- Animal proteins ---- PHD finger protein 23 Source.202: DFBPPR20216 ---- Animal proteins ---- Calcium-responsive transactivator Source.203: DFBPPR20219 ---- Animal proteins ---- Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 Source.204: DFBPPR20311 ---- Animal proteins ---- Peroxisomal membrane protein 11B Source.205: DFBPPR20350 ---- Animal proteins ---- Pinin Source.206: DFBPPR20489 ---- Animal proteins ---- Translocon-associated protein subunit alpha Source.207: DFBPPR20610 ---- Animal proteins ---- Cleft lip and palate transmembrane protein 1 homolog Source.208: DFBPPR20636 ---- Animal proteins ---- Transforming growth factor-beta receptor-associated protein 1 Source.209: DFBPPR20684 ---- Animal proteins ---- Doublesex- and mab-3-related transcription factor A2 Source.210: DFBPPR20743 ---- Animal proteins ---- Myozenin-1 Source.211: DFBPPR20782 ---- Animal proteins ---- Deoxynucleotidyltransferase terminal-interacting protein 1 Source.212: DFBPPR20800 ---- Animal proteins ---- Augurin Source.213: DFBPPR20870 ---- Animal proteins ---- HMG box-containing protein 1 Source.214: DFBPPR20878 ---- Animal proteins ---- Protein SMG9 Source.215: DFBPPR20983 ---- Animal proteins ---- Plakophilin-3 Source.216: DFBPPR21025 ---- Animal proteins ---- Radial spoke head protein 3 homolog Source.217: DFBPPR21079 ---- Animal proteins ---- Alpha/beta hydrolase domain-containing protein 17A Source.218: DFBPPR21186 ---- Animal proteins ---- 40S ribosomal protein S2 Source.219: DFBPPR21214 ---- Animal proteins ---- Prostate tumor-overexpressed gene 1 protein homolog Source.220: DFBPPR21217 ---- Animal proteins ---- GA-binding protein subunit beta-1 Source.221: DFBPPR21232 ---- Animal proteins ---- Cerebellin-3 Source.222: DFBPPR21282 ---- Animal proteins ---- Spindle and centriole-associated protein 1 Source.223: DFBPPR21332 ---- Animal proteins ---- ER membrane protein complex subunit 4 Source.224: DFBPPR21333 ---- Animal proteins ---- DDB1- and CUL4-associated factor 15 Source.225: DFBPPR21339 ---- Animal proteins ---- Zinc finger protein 692 Source.226: DFBPPR21354 ---- Animal proteins ---- RNA polymerase II elongation factor ELL3 Source.227: DFBPPR21363 ---- Animal proteins ---- Pleckstrin homology-like domain family A member 2 Source.228: DFBPPR21387 ---- Animal proteins ---- Surfeit locus protein 4 Source.229: DFBPPR21388 ---- Animal proteins ---- Zinc finger CCCH-type with G patch domain-containing protein Source.230: DFBPPR21399 ---- Animal proteins ---- Trafficking protein particle complex subunit 6A Source.231: DFBPPR21459 ---- Animal proteins ---- RELT-like protein 2 Source.232: DFBPPR21471 ---- Animal proteins ---- Gap junction alpha-5 protein Source.233: DFBPPR21546 ---- Animal proteins ---- Mediator of RNA polymerase II transcription subunit 29 Source.234: DFBPPR21616 ---- Animal proteins ---- Olfactomedin-like protein 3 Source.235: DFBPPR21745 ---- Animal proteins ---- Mastermind-like protein 2 Source.236: DFBPPR21759 ---- Animal proteins ---- Eukaryotic translation initiation factor 2D Source.237: DFBPPR21781 ---- Animal proteins ---- WD repeat-containing protein 1 Source.238: DFBPPR21795 ---- Animal proteins ---- CCAAT/enhancer-binding protein gamma Source.239: DFBPPR21829 ---- Animal proteins ---- Mitochondrial 2-oxodicarboxylate carrier Source.240: DFBPPR21952 ---- Animal proteins ---- Conserved oligomeric Golgi complex subunit 6 Source.241: DFBPPR21983 ---- Animal proteins ---- IGF-like family receptor 1 Source.242: DFBPPR22047 ---- Animal proteins ---- WD repeat-containing protein 6 Source.243: DFBPPR22085 ---- Animal proteins ---- Zinc finger protein 512 Source.244: DFBPPR22146 ---- Animal proteins ---- Leucine-rich repeat-containing protein 41 Source.245: DFBPPR22199 ---- Animal proteins ---- SCAN domain-containing protein 1 Source.246: DFBPPR22203 ---- Animal proteins ---- Serum amyloid A-4 protein Source.247: DFBPPR22241 ---- Animal proteins ---- von Willebrand factor A domain-containing protein 7 Source.248: DFBPPR22415 ---- Animal proteins ---- Methyltransferase-like protein 9 Source.249: DFBPPR8548 ---- Animal proteins ---- Interstitial collagenase Source.250: DFBPPR8569 ---- Animal proteins ---- Ryanodine receptor 1 Source.251: DFBPPR8968 ---- Animal proteins ---- Vasopressin-neurophysin 2-copeptin Source.252: DFBPPR9063 ---- Animal proteins ---- Oxytocin-neurophysin 1 Source.253: DFBPPR9073 ---- Animal proteins ---- Vitronectin Source.254: DFBPPR9078 ---- Animal proteins ---- Neurofilament medium polypeptide Source.255: DFBPPR9117 ---- Animal proteins ---- Cell cycle exit and neuronal differentiation protein 1 Source.256: DFBPPR9206 ---- Animal proteins ---- Serine/threonine-protein phosphatase 1 regulatory subunit 10 Source.257: DFBPPR9300 ---- Animal proteins ---- Adrenodoxin, mitochondrial Source.258: DFBPPR9513 ---- Animal proteins ---- Small conductance calcium-activated potassium channel protein 3 Source.259: DFBPPR9565 ---- Animal proteins ---- Melanoma-associated antigen D1 Source.260: DFBPPR9570 ---- Animal proteins ---- Gastrokine-1 Source.261: DFBPPR9741 ---- Animal proteins ---- Syndecan-4 Source.262: DFBPPR9744 ---- Animal proteins ---- Protein phosphatase 1 regulatory subunit 14B Source.263: DFBPPR9885 ---- Animal proteins ---- B-cell CLL/lymphoma 9 protein Source.264: DFBPPR9910 ---- Animal proteins ---- Serum amyloid A-2 protein Source.265: DFBPPR9936 ---- Animal proteins ---- Serum amyloid A-4 protein Source.266: DFBPPR9939 ---- Animal proteins ---- Tctex1 domain-containing protein 4 Source.267: DFBPPR10007 ---- Animal proteins ---- Protein Wnt-1 Source.268: DFBPPR10028 ---- Animal proteins ---- CCAAT/enhancer-binding protein beta Source.269: DFBPPR10127 ---- Animal proteins ---- Heat shock factor protein 1 Source.270: DFBPPR10141 ---- Animal proteins ---- Chondroitin sulfate proteoglycan 5 Source.271: DFBPPR10160 ---- Animal proteins ---- Collagen alpha-2(I) chain Source.272: DFBPPR10238 ---- Animal proteins ---- COUP transcription factor 2 Source.273: DFBPPR10251 ---- Animal proteins ---- Integrin alpha-6 Source.274: DFBPPR10283 ---- Animal proteins ---- Mothers against decapentaplegic homolog 6 Source.275: DFBPPR10284 ---- Animal proteins ---- Non-specific lipid-transfer protein Source.276: DFBPPR10392 ---- Animal proteins ---- Transcription factor p65 Source.277: DFBPPR10422 ---- Animal proteins ---- Collagen alpha-1(XII) chain Source.278: DFBPPR10445 ---- Animal proteins ---- Collagen alpha-1(XVII) chain Source.279: DFBPPR10468 ---- Animal proteins ---- KH domain-containing, RNA-binding, signal transduction-associated protein 1 Source.280: DFBPPR10470 ---- Animal proteins ---- Collagen alpha-1(III) chain Source.281: DFBPPR10488 ---- Animal proteins ---- Sulfite oxidase Source.282: DFBPPR10495 ---- Animal proteins ---- Y-box-binding protein 1 Source.283: DFBPPR10528 ---- Animal proteins ---- Far upstream element-binding protein 2 Source.284: DFBPPR10556 ---- Animal proteins ---- Tenascin-R Source.285: DFBPPR10605 ---- Animal proteins ---- Elastin Source.286: DFBPPR10607 ---- Animal proteins ---- Collagen alpha-2(VI) chain Source.287: DFBPPR10630 ---- Animal proteins ---- Contactin-2 Source.288: DFBPPR10635 ---- Animal proteins ---- Dual serine/threonine and tyrosine protein kinase Source.289: DFBPPR10638 ---- Animal proteins ---- Cellular tumor antigen p53 Source.290: DFBPPR10764 ---- Animal proteins ---- Probable ATP-dependent RNA helicase DDX6 Source.291: DFBPPR10821 ---- Animal proteins ---- Dual specificity mitogen-activated protein kinase kinase 2 Source.292: DFBPPR10838 ---- Animal proteins ---- Protein lin-28 homolog A Source.293: DFBPPR10855 ---- Animal proteins ---- Transcription factor SOX-3 Source.294: DFBPPR10890 ---- Animal proteins ---- Thioredoxin reductase-like selenoprotein T Source.295: DFBPPR10927 ---- Animal proteins ---- Frizzled-7 Source.296: DFBPPR10928 ---- Animal proteins ---- Ubiquitin carboxyl-terminal hydrolase 28 Source.297: DFBPPR10969 ---- Animal proteins ---- Paraspeckle component 1 Source.298: DFBPPR10975 ---- Animal proteins ---- Cytoplasmic dynein 1 light intermediate chain 1 Source.299: DFBPPR10990 ---- Animal proteins ---- Period circadian protein homolog 2 Source.300: DFBPPR11012 ---- Animal proteins ---- Cleavage and polyadenylation specificity factor subunit 6 Source.301: DFBPPR11059 ---- Animal proteins ---- Cell cycle control protein 50A Source.302: DFBPPR11089 ---- Animal proteins ---- Endosomal/lysosomal potassium channel TMEM175 Source.303: DFBPPR11158 ---- Animal proteins ---- Phosphatase and actin regulator 1 Source.304: DFBPPR11311 ---- Animal proteins ---- Forkhead box protein D1 Source.305: DFBPPR11329 ---- Animal proteins ---- Bone sialoprotein 2 Source.306: DFBPPR11343 ---- Animal proteins ---- Transcription factor Sp8 Source.307: DFBPPR11396 ---- Animal proteins ---- 26S proteasome regulatory subunit 4 Source.308: DFBPPR11405 ---- Animal proteins ---- Cadherin-related family member 1 Source.309: DFBPPR11536 ---- Animal proteins ---- Putative Polycomb group protein ASXL2 Source.310: DFBPPR11656 ---- Animal proteins ---- Hsp90 co-chaperone Cdc37 Source.311: DFBPPR11720 ---- Animal proteins ---- Interleukin-17 receptor D Source.312: DFBPPR11787 ---- Animal proteins ---- V-type proton ATPase subunit B Source.313: DFBPPR11795 ---- Animal proteins ---- Class E basic helix-loop-helix protein 22 Source.314: DFBPPR11796 ---- Animal proteins ---- Surfeit locus protein 4 Source.315: DFBPPR11831 ---- Animal proteins ---- Protein lin-28 homolog B Source.316: DFBPPR11881 ---- Animal proteins ---- DDB1- and CUL4-associated factor 12 Source.317: DFBPPR11966 ---- Animal proteins ---- Protein CREG1 Source.318: DFBPPR11981 ---- Animal proteins ---- Histone deacetylase complex subunit SAP130 Source.319: DFBPPR12111 ---- Animal proteins ---- WD repeat-containing protein 1 Source.320: DFBPPR12222 ---- Animal proteins ---- Coiled-coil domain-containing protein 43 Source.321: DFBPPR12281 ---- Animal proteins ---- Ryanodine receptor 1 Source.322: DFBPPR12292 ---- Animal proteins ---- Protein kinase C gamma type Source.323: DFBPPR12321 ---- Animal proteins ---- Voltage-dependent N-type calcium channel subunit alpha-1B Source.324: DFBPPR12371 ---- Animal proteins ---- Y-box-binding protein 1 Source.325: DFBPPR12411 ---- Animal proteins ---- Translation initiation factor eIF-2B subunit epsilon Source.326: DFBPPR12426 ---- Animal proteins ---- Dual specificity tyrosine-phosphorylation-regulated kinase 1A Source.327: DFBPPR12451 ---- Animal proteins ---- Non-specific lipid-transfer protein Source.328: DFBPPR12511 ---- Animal proteins ---- Serine/threonine-protein kinase 17A Source.329: DFBPPR12516 ---- Animal proteins ---- Indolethylamine N-methyltransferase Source.330: DFBPPR12545 ---- Animal proteins ---- Galectin-3 Source.331: DFBPPR12596 ---- Animal proteins ---- Alpha-sarcoglycan Source.332: DFBPPR12764 ---- Animal proteins ---- Keratin, type II cytoskeletal 3 Source.333: DFBPPR12848 ---- Animal proteins ---- Sarcoplasmic reticulum histidine-rich calcium-binding protein Source.334: DFBPPR12892 ---- Animal proteins ---- Translocon-associated protein subunit alpha Source.335: DFBPPR12928 ---- Animal proteins ---- Regulatory solute carrier protein family 1 member 1 Source.336: DFBPPR12944 ---- Animal proteins ---- Multidrug and toxin extrusion protein 1 Source.337: DFBPPR12952 ---- Animal proteins ---- Serum amyloid A-1 protein Source.338: DFBPPR12974 ---- Animal proteins ---- Serum amyloid A-3 protein Source.339: DFBPPR12976 ---- Animal proteins ---- Eukaryotic translation initiation factor 4 gamma 1 Source.340: DFBPPR13047 ---- Animal proteins ---- Elongation factor 1-delta Source.341: DFBPPR13055 ---- Animal proteins ---- Serum amyloid A-2 protein Source.342: DFBPPR13217 ---- Animal proteins ---- Interstitial collagenase Source.343: DFBPPR13280 ---- Animal proteins ---- Oxytocin-neurophysin 1 Source.344: DFBPPR13312 ---- Animal proteins ---- Alpha-2B adrenergic receptor Source.345: DFBPPR13325 ---- Animal proteins ---- Serum amyloid A protein Source.346: DFBPPR13402 ---- Animal proteins ---- Neurophysin 2 Source.347: DFBPPR13464 ---- Animal proteins ---- Interferon tau Source.348: DFBPPR13484 ---- Animal proteins ---- Heat shock-related 70 kDa protein 2 Source.349: DFBPPR13519 ---- Animal proteins ---- Neurogranin Source.350: DFBPPR13633 ---- Animal proteins ---- Interferon tau-2 Source.351: DFBPPR13645 ---- Animal proteins ---- Interferon tau-6 Source.352: DFBPPR13653 ---- Animal proteins ---- Interferon tau-11 Source.353: DFBPPR13659 ---- Animal proteins ---- Oxytocin-neurophysin 1 Source.354: DFBPPR13670 ---- Animal proteins ---- Vasopressin-neurophysin 2-copeptin Source.355: DFBPPR13694 ---- Animal proteins ---- Interferon tau-1 Source.356: DFBPPR13720 ---- Animal proteins ---- Interferon tau-10 Source.357: DFBPPR13742 ---- Animal proteins ---- Interferon tau-5 Source.358: DFBPPR13743 ---- Animal proteins ---- Interferon tau-9 Source.359: DFBPPR13744 ---- Animal proteins ---- Interferon tau-8 Source.360: DFBPPR13745 ---- Animal proteins ---- Interferon tau-7 Source.361: DFBPPR13748 ---- Animal proteins ---- Interferon tau-4 Source.362: DFBPPR13805 ---- Animal proteins ---- Serum amyloid A protein Source.363: DFBPPR13924 ---- Animal proteins ---- Zinc finger CCCH-type with G patch domain-containing protein Source.364: DFBPPR13937 ---- Animal proteins ---- Prostaglandin E2 receptor EP3 subtype Source.365: DFBPPR14136 ---- Marine protein ---- Lysine-specific demethylase 8 Source.366: DFBPPR14151 ---- Marine protein ---- Peptidyl-tRNA hydrolase ICT1, mitochondrial Source.367: DFBPPR14175 ---- Marine protein ---- Draxin-B Source.368: DFBPPR14351 ---- Marine protein ---- Photosystem II CP43 reaction center protein Source.369: DFBPPR14377 ---- Marine protein ---- DNA-directed RNA polymerase subunit beta Source.370: DFBPPR14381 ---- Marine protein ---- Pyruvate dehydrogenase E1 component subunit beta Source.371: DFBPPR14548 ---- Marine protein ---- Mineralocorticoid receptor Source.372: DFBPPR14564 ---- Marine protein ---- Piwi-like protein 2 Source.373: DFBPPR14569 ---- Marine protein ---- Collagen alpha-2(I) chain Source.374: DFBPPR14899 ---- Microorganism protein ---- Transcription elongation factor SPT5 Source.375: DFBPPR15200 ---- Microorganism protein ---- Protein SPT3 Source.376: DFBPPR15519 ---- Microorganism protein ---- Mitochondrial genome maintenance protein MGM101 Source.377: DFBPPR15687 ---- Microorganism protein ---- 40S ribosomal protein S14 Source.378: DFBPPR7793 ---- Plant protein ---- Photosystem II CP43 reaction center protein Source.379: DFBPPR7820 ---- Plant protein ---- DNA-directed RNA polymerase subunit beta Source.380: DFBPPR8059 ---- Plant protein ---- Photosystem II CP43 reaction center protein Source.381: DFBPPR8095 ---- Plant protein ---- Profilin-1 Source.382: DFBPPR8104 ---- Plant protein ---- DNA-directed RNA polymerase subunit beta Source.383: DFBPPR8237 ---- Plant protein ---- Photosystem II CP43 reaction center protein Source.384: DFBPPR8272 ---- Plant protein ---- DNA-directed RNA polymerase subunit beta
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

DPP IV-inhibitory activity

The peptide showed potent inhibitory activity for Dipeptidyl-peptidase IV (EC 3.4.14.5) with a low K_m value of 0.28 mM.

Table 1 Kinetic parameters of dipeptidyl-aminopeptidase IV with peptide
Substrate	S₀ (mM)	K_m (mM)	V (μmol × 10^-6s^-1)	E₀^a (μmol × 10^-6)	K_cat (s^-1)	K_cat/K_m (s^-1 mM^-1)
Gly-_L-Pro-Gly-Gly	0.2-2.5	0.28	6.5	0.208	31.3	112
^a Molecular weight of the enzyme = 230000.

Specific target protein(s)

Specific Target Protein(s):
Dipeptidyl peptidase 4

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Non-bitter taste ^prediction

SMILES

NCC(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)NCC(=O)O

Preparation method

Mode of preparation	Synthesis
Enzyme(s)/starter culture	Synthesis peptide

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

DFBP

[D1]	DFBPANTH0045
[D2]	DFBPMUFU0720

BIOPEP-UWM

[D3]

2755, 3458, 3462

APD

[D4]

BioPepDB

[D5]

MBPDB

[D6]

Reference(s)

Primary literature	Bella, A.M., Erickson, R.H., Kim, Y.S. Rat intestinal brush border membrane dipeptidyl-aminopeptidase IV: Kinetic properties and substrate specificities of the purified enzyme. Archives of Biochemistry and Biophysics. 1982, 218, 156-62. DOI: 10.1016/0003-9861(82)90330-7
Other literature(s)	N.D
PubDate	1982