Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPGAGP0048(γ-Glutamyl peptides)

DFBP ID	DFBPGAGP0048
Peptide sequence	γ-EM
Type	Native peptide
Peptide/Function name	γ-Glutamyl peptide

Function-activity relationship

Main bioactivity	Calcium-sensing receptor (CaSR) activation
Otheir bioactivity	DPP IV-inhibitory activity ^[D1], Multifunctional activity ^[D2]

Calculated physicochemical properties

Three-letter amino acid

γ-Glu-Met

Single-letter amino acid

γ-EM

Peptide length

Peptide mass

Experimental mass	Theoretical mass
N.D	278.32 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

3.34 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

-0.8000^c

Hydrophilic residue ratio

50%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Synthesis
Organism/Source	Synthesis peptide
Precursor protein	Synthesis peptide
Residue position	N.D
Precursor protein(s) search	No matching precursor protein found
Link-research Inductive analysis	Link 1: DFBPGAGP0007----Fermented food (cheese)----N.D Link 2: DFBPGAGP0038----Fermented food (Parmesan Cheese)----N.D Link 3: DFBPGAGP0045----Fermented food (Sourdough Fermentation)----N.D

Biological/Functional activity & target protein

Calcium-sensing receptor (CaSR) activation	N.D
Specific target protein(s)	N.D

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Non-bitter taste ^prediction

SMILES

N.D

Preparation method

Mode of preparation	Synthesis
Enzyme(s)/starter culture	Commercial synthetic γ-Glu-Met with 98% purity (based on MS analysis) were purchased from the Peptide Biological Technology Co., Ltd. (Nanjing, China).

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

DFBP

[D1]	DFBPDPIV0241
[D2]	DFBPMUFU0738

[D3]

[D4]

[D5]

[D6]

Reference(s)

Primary literature	Yang, J., et al. γ-Glu-Met synthesised using a bacterial glutaminase as a potential inhibitor of dipeptidyl peptidase IV. Int. J. Food Sci. Technol. 2018;53(5):1166-1175. DOI: 10.1111/ijfs.13692
Other literature(s)	N.D
PubDate	2018