(1) Serum cholesterol levels were significantly lower in the protamine and RPR groups than in the control group. (2) White adipose tissue weight was significantly decreased in the protamine and RPR groups. (3) The fecal excretion of cholesterol and bile acid was significantly higher in the protamine and RPR groups than in the control group. (4) Reseachers also observed a significant decrease in the expression of hepatic SCD1, SREBP1, and adipocyte FAS mRNA, and significantly increased expression of hepatic PPAR alpha and adipocyte PPAR gamma 1 mRNA in the protamine group. |