Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPIMMU0009(Immunomodulatory peptide)

DFBP ID	DFBPIMMU0009
Peptide sequence	SGFAP
Type	Native peptide
Peptide/Function name	Immunomodulatory peptide

Function-activity relationship

Main bioactivity	Immunomodulatory activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

Ser-Gly-Phe-Ala-Pro

Single-letter amino acid

SGFAP

Peptide length

Peptide mass

Experimental mass	Theoretical mass
N.D	477.51 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

5.97 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

0.3600^c

Hydrophilic residue ratio

80%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Plant
Organism/Source	Soybean
Precursor protein	Seed proteins
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR1427 ---- Plant proteins ---- Probable esterase D14L Source.2: DFBPPR2948 ---- Plant proteins ---- Expansin-A25 Source.3: DFBPPR4973 ---- Plant proteins ---- Glycinin G2 Source.4: DFBPPR4992 ---- Plant proteins ---- Glycinin G3 Source.5: DFBPPR5396 ---- Plant proteins ---- DELLA protein DWARF8 Source.6: DFBPPR5764 ---- Plant proteins ---- Cysteine proteinase 1 Source.7: DFBPPR19255 ---- Animal proteins ---- Neutrophil cytosol factor 2 Source.8: DFBPPR21018 ---- Animal proteins ---- Solute carrier family 22 member 17 Source.9: DFBPPR11117 ---- Animal proteins ---- Transcription factor jun-D
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

Immunomodulatory activity	Significantly stimulated the proliferation of splenocytes of mice.
Specific target protein(s)	N.D

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Non-bitter taste ^prediction

SMILES

N[C@@]([H])(CO)C(=O)NCC(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)O

Preparation method

Mode of preparation	Enzymatic hydrolysis
Enzyme(s)/starter culture	Hydrolysis with pepsin.

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Chen, J.-r., Suetsuna, K., Yamauchi, F. Isolation and characterization of immunostimulative peptides from soybean. The Journal of Nutritional Biochemistry. 1995, 6, 310-3. DOI: 10.1016/0955-2863(95)00022-R
Other literature(s)	[1] Chalamaiah M, Yu W, Wu J. Immunomodulatory and anticancer protein hydrolysates (peptides) from food proteins: A review.[J]. Food Chemistry, 2018, 245:205-222.
PubDate	1995