Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPIMMU0088(Immunomodulatory peptide)

DFBP ID	DFBPIMMU0088
Peptide sequence	QRPR
Type	Native peptide
Peptide/Function name	Immunomodulatory peptide

Function-activity relationship

Main bioactivity	Immunomodulatory activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

Gln-Arg-Pro-Arg

Single-letter amino acid

QRPR

Peptide length

Peptide mass

Experimental mass	Theoretical mass
N.D	555.63 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

12.50 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

-3.5250^c

Hydrophilic residue ratio

25%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Plant
Organism/Source	Soybean
Precursor protein	Seed protein
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR0819 ---- Plant proteins ---- Homeobox-leucine zipper protein ROC1 Source.2: DFBPPR0824 ---- Plant proteins ---- Homeobox-leucine zipper protein ROC2 Source.3: DFBPPR0828 ---- Plant proteins ---- Homeobox-leucine zipper protein ROC7 Source.4: DFBPPR0927 ---- Plant proteins ---- Serine/threonine-protein kinase TOR Source.5: DFBPPR1362 ---- Plant proteins ---- Protein ROS1C Source.6: DFBPPR1386 ---- Plant proteins ---- Transcription factor LATE FLOWERING Source.7: DFBPPR1447 ---- Plant proteins ---- Two-component response regulator-like PRR37 Source.8: DFBPPR1526 ---- Plant proteins ---- Flavanone 3-dioxygenase 2 Source.9: DFBPPR2231 ---- Plant proteins ---- Serine/threonine-protein kinase Nek5 Source.10: DFBPPR2380 ---- Plant proteins ---- Protein disulfide isomerase-like 5-3 Source.11: DFBPPR2672 ---- Plant proteins ---- 63 kDa globulin-like protein Source.12: DFBPPR2959 ---- Plant proteins ---- Serine/threonine-protein phosphatase BSL2 homolog Source.13: DFBPPR3194 ---- Plant proteins ---- G patch domain-containing protein TGH homolog Source.14: DFBPPR3275 ---- Plant proteins ---- DEAD-box ATP-dependent RNA helicase 37 Source.15: DFBPPR3466 ---- Plant proteins ---- Two-component response regulator-like PRR73 Source.16: DFBPPR3678 ---- Plant proteins ---- Kinesin-like protein KIN-14F Source.17: DFBPPR4130 ---- Plant proteins ---- Two-component response regulator-like PRR95 Source.18: DFBPPR4552 ---- Plant proteins ---- B3 domain-containing protein Os07g0563300 Source.19: DFBPPR4633 ---- Plant proteins ---- B3 domain-containing protein Os07g0183700 Source.20: DFBPPR4965 ---- Plant proteins ---- Glycinin G1 Source.21: DFBPPR5788 ---- Plant proteins ---- Globulin-1 S allele Source.22: DFBPPR7342 ---- Plant proteins ---- 40S ribosomal protein S7 Source.23: DFBPPR7599 ---- Milk proteins ---- Apelin Source.24: DFBPPR8513 ---- Milk proteins ---- Apelin Source.25: DFBPPR15971 ---- Animal proteins ---- C-X-C chemokine receptor type 4 Source.26: DFBPPR16440 ---- Animal proteins ---- Inactive rhomboid protein 2 Source.27: DFBPPR16774 ---- Animal proteins ---- Annexin A1 isoform p35 Source.28: DFBPPR17438 ---- Animal proteins ---- Disintegrin and metalloproteinase domain-containing protein 10 Source.29: DFBPPR17858 ---- Animal proteins ---- Calsenilin Source.30: DFBPPR17866 ---- Animal proteins ---- PIH1 domain-containing protein 1 Source.31: DFBPPR17890 ---- Animal proteins ---- Neuronal acetylcholine receptor subunit alpha-3 Source.32: DFBPPR17961 ---- Animal proteins ---- Cyclin-dependent kinase 12 Source.33: DFBPPR18154 ---- Animal proteins ---- WD repeat-containing protein 44 Source.34: DFBPPR18236 ---- Animal proteins ---- Latent-transforming growth factor beta-binding protein 2 Source.35: DFBPPR18410 ---- Animal proteins ---- Thromboxane A2 receptor Source.36: DFBPPR18782 ---- Animal proteins ---- Parathyroid hormone Source.37: DFBPPR18817 ---- Animal proteins ---- Protein argonaute-3 Source.38: DFBPPR19706 ---- Animal proteins ---- PHD finger protein 10 Source.39: DFBPPR20088 ---- Animal proteins ---- L-threonine 3-dehydrogenase, mitochondrial Source.40: DFBPPR20513 ---- Animal proteins ---- Rho GTPase-activating protein 29 Source.41: DFBPPR20519 ---- Animal proteins ---- Spermatogenesis-associated protein 6 Source.42: DFBPPR20665 ---- Animal proteins ---- PWWP domain-containing DNA repair factor 3A Source.43: DFBPPR20865 ---- Animal proteins ---- Methionine adenosyltransferase 2 subunit beta Source.44: DFBPPR21006 ---- Animal proteins ---- AT-rich interactive domain-containing protein 5A Source.45: DFBPPR21179 ---- Animal proteins ---- Eukaryotic translation initiation factor 4H Source.46: DFBPPR21749 ---- Animal proteins ---- Protein CUSTOS Source.47: DFBPPR22019 ---- Animal proteins ---- ATP-binding cassette sub-family F member 2 Source.48: DFBPPR22226 ---- Animal proteins ---- Pleckstrin homology domain-containing family O member 2 Source.49: DFBPPR22522 ---- Animal proteins ---- Coiled-coil domain-containing protein 126 Source.50: DFBPPR22763 ---- Animal proteins ---- Uncharacterized protein C19orf71 homolog Source.51: DFBPPR8584 ---- Animal proteins ---- Disintegrin and metalloproteinase domain-containing protein 10 Source.52: DFBPPR8671 ---- Animal proteins ---- C-X-C chemokine receptor type 4 Source.53: DFBPPR8799 ---- Animal proteins ---- Parathyroid hormone Source.54: DFBPPR9326 ---- Animal proteins ---- Tripartite motif-containing protein 26 Source.55: DFBPPR9375 ---- Animal proteins ---- L-threonine 3-dehydrogenase, mitochondrial Source.56: DFBPPR10096 ---- Animal proteins ---- BDNF/NT-3 growth factors receptor Source.57: DFBPPR10168 ---- Animal proteins ---- TALPID3 protein Source.58: DFBPPR10174 ---- Animal proteins ---- Serine/threonine-protein kinase SIK2 Source.59: DFBPPR10434 ---- Animal proteins ---- Parathyroid hormone Source.60: DFBPPR10653 ---- Animal proteins ---- Contactin-1 Source.61: DFBPPR10941 ---- Animal proteins ---- Chromodomain-helicase-DNA-binding protein 1 Source.62: DFBPPR11191 ---- Animal proteins ---- Protein argonaute-3 Source.63: DFBPPR12729 ---- Animal proteins ---- Solute carrier family 22 member 2 Source.64: DFBPPR12833 ---- Animal proteins ---- Cullin-5 Source.65: DFBPPR13209 ---- Animal proteins ---- Parathyroid hormone Source.66: DFBPPR13611 ---- Animal proteins ---- C-X-C chemokine receptor type 4 Source.67: DFBPPR14303 ---- Marine protein ---- Phycobilisome rod-core linker polypeptide cpcG
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

Immunomodulatory activity	The peptide might have immunostimulatingeffects.
Specific target protein(s)	N.D

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Non-bitter taste ^prediction

SMILES

N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

Preparation method

Mode of preparation	Enzymatic hydrolysis
Enzyme(s)/starter culture	The peptide was released by tryptic digestion of soybean protein.

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Yoshikawa M, Kishi K, Takahashi M, Watanabe A, Miyamura T, Yamazaki M, Chiba H. Immunostimulating peptide derived from soybean protein. Ann N Y Acad Sci. 1993 Jun 23;685:375-6. PMID: 8363244 DOI: 10.1111/j.1749-6632.1993.tb35892.x
Other literature(s)	N.D
PubDate	1993