DFBP ID - DFBPMIBP0022(Mineral-binding peptide)

DFBP ID DFBPMIBP0022 Peptide sequence RKKKCKGNCCYTPQ Type Native peptide Peptide/Function name Mineral-binding petpide, Fe 8

Function-activity relationship

Main bioactivity Mineral-binding activity Otheir bioactivity N.D

Calculated physicochemical properties

Three-letter amino acid Arg-Lys-Lys-Lys-Cys-Lys-Gly-Asn-Cys-Cys-Tyr-Thr-Pro-Gln Single-letter amino acid RKKKCKGNCCYTPQ Peptide length 14 Peptide mass Experimental mass Theoretical mass N.D 1657.02 Da c Net charge 0.00 c Isoelectric point (pI) 9.98 c IC50 N.D pIC50 N.D GRAVY -1.6857 c Hydrophilic residue ratio 14.29% c Peptide calculator To calculate the physicochemical properties of bioactive peptide.

Peptide source & Food-borne protein(s) search

Classification Synthesis Organism/Source Synthesis peptide Precursor protein Synthesis peptide Residue position N.D Precursor protein(s) search No matching precursor protein found Link-research Inductive analysis There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

Mineral-binding activity As shown in Figure 1, the peptide Fe 8 showed chalcopyrite-binding activity. Specific target protein(s) N.D

Taste properties & Structure

Bitterness Literature report N.D Bitter prediction tools Non-bitter taste prediction SMILES N.D

Preparation method

Mode of preparation Synthesis Enzyme(s)/starter culture Synthesis peptide

Stability & Cytotoxicity

Peptide stability Literature report: N.D EHP-Tool: Enzymatic Hydrolysis Prediction Tool (EHP-Tool) Peptide cytotoxicity Literature report: N.D Prediction: ToxinPred

Additional information

Additional information N.D

Database cross-references

BIOPEP-UWM [D1] -

APD [D2] -

BioPepDB [D3] -

MBPDB [D4] -

Reference(s)

Primary literature Curtis S, Lederer FL, Dunbar WS, MacGillivray RT. Identification of mineral-binding peptides that discriminate between chalcopyrite and enargite. Biotechnol Bioeng. 2017 May;114(5):998-1005. PMID: 27861731 DOI: 10.1002/bit.26218 Other literature(s) N.D PubDate 2016