Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPNEUR0002(Neuropeptide peptide)

DFBP ID	DFBPNEUR0002
Peptide sequence	YLNVVTRPRF
Type	Native peptide
Peptide/Function name	Neuropeptide, PP (C-terminal)

Function-activity relationship

Main bioactivity	Neuropeptide activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

Tyr-Leu-Asn-Val-Val-Thr-Arg-Pro-Arg-Phe

Single-letter amino acid

YLNVVTRPRF

Peptide length

Peptide mass

Experimental mass	Theoretical mass
N.D	1264.48 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

11.20 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

-0.1100^c

Hydrophilic residue ratio

50%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Animal
Organism/Source	Alligator (Alligator mississippiensis)
Precursor protein	Insulin and Pancreatic Polypeptide
Residue position	N.D
Precursor protein(s) search	No matching precursor protein found
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

Neuropeptide activity	Peptide YLNVVTRPRFamide showed neuromodulatory activity (data not shown).
Specific target protein(s)	N.D

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Bitter taste ^prediction

SMILES

N.D

Preparation method

Mode of preparation	Extraction
Enzyme(s)/starter culture	The insulin, glucagon, pancreatic polypeptide, and somatostatin contents of acid-alcohol extracts of alligator pancreas have been estimated by heterologous radioimmunoassay, and the insulin, glucagon, and pancreatic polypeptide have been isolated.

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Lance V, Hamilton JW, Rouse JB, Kimmel JR, Pollock HG. Isolation and characterization of reptilian insulin, glucagon, and pancreatic polypeptide: complete amino acid sequence of alligator (Alligator mississippiensis) insulin and pancreatic polypeptide. Gen Comp Endocrinol. 1984 Jul;55(1):112-24. PMID: 6146554 DOI: 10.1016/0016-6480(84)90135-7
Other literature(s)	[1] Gaus G, Doble KE, Price DA, Greenberg MJ, Lee TD, Battelle BA. The Sequences of Five Neuropeptides Isolated from Limulus using Antisera to FMRFamide. Biol Bull. 1993 Jun;184(3):322-329.
PubDate	1984