Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPOPIO0111(Opioid peptide)

DFBP ID	DFBPOPIO0111
Peptide sequence	ALKAWSVAR
Type	Native peptide
Peptide/Function name	Opioid peptide, Albutensin A

Function-activity relationship

Main bioactivity	Opioid activity
Otheir bioactivity	ACE-inhibitory activity ^[D1], Multifunctional activity ^[D2]

Calculated physicochemical properties

Three-letter amino acid

Ala-Leu-Lys-Ala-Trp-Ser-Val-Ala-Arg

Single-letter amino acid

ALKAWSVAR

Peptide length

Peptide mass

Experimental mass	Theoretical mass
N.D	1001.18 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

11.54 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

0.3667^c

Hydrophilic residue ratio

66.67%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Animal
Organism/Source	Bovine
Precursor protein	Bovine serum albumin (BSA)
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR16797 ---- Animal proteins ---- Albumin Source.2: DFBPPR13788 ---- Animal proteins ---- Albumin
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

Opioid activity

Opioid activity	References
Opioid antagonist	[1]

Specific target protein(s)

N.D

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Non-bitter taste ^prediction

SMILES

N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

Preparation method

Mode of preparation	Synthesis
Enzyme(s)/starter culture	Synthesis peptide

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

DFBP

[D1]	DFBPACEI0366
[D2]	DFBPMUFU0112

[D3]

[D4]

[D5]

[D6]

Reference(s)

Primary literature	Yoshikawa, M. Casoxin D, an opioid antagonist/ileum-contracting/vasorelaxing peptide derived from human alphas1-casein. 1994, pp. 43-8.
Other literature(s)	[1] Kostyra E, Sienkiewiczszłapka E, Jarmołowska B, et al. Opioid peptides derived from milk proteins.[J]. Polish Journal of Food & Nutrition Sciences, 2004.
PubDate	1994