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Enzyme - EC 3.4.21.6
DFBP ID DFBPENZY0017
EC Number EC 3.4.21.6
Term Coagulation factor Xa
Introduction
DFBP ID DFBPENZY0017
EC Number EC 3.4.21.6
Accepted Name

Recommended name:
     • Coagulation factor Xa (EC:3.4.21.6)
Alternative name(s):
     • Prothrombase
     • Prothrombinase
     • Stuart factor
     • Thrombokinase

Cleavage sites
Number
Pn------
P4
P3
P2
P1
Cleavage sites
P1'
P2'
------Pm'
site.1------
A,F,G,I,L,T,V or MD or EG
R
-|---
------
Cross-references
Database(s)
ExPASy - ENZYMEEC 3.4.21.6
MEROPS databaseEnzyme ID S01.216
ExplorEnz databaseEC 3.4.21.6
Reference(s)
Literature(s)

[1] Fujikawa, K. and Davie, E.W. Bovine factor X (Stuart factor). Methods Enzymol. 45 (1976) 89–95. [DOI] [PMID: 1012041]
[2] Jesty, J. and Nemerson, Y. The activation of bovine coagulation factor X. Methods Enzymol. 45 (1976) 95–107. [DOI] [PMID: 1012042]
[3] Davie, E.W., Fujikawa, K., Kurachi, K. and Kisiel, W. The role of serine proteases in the blood coagulation cascade. Adv. Enzymol. 48 (1979) 277–318. [PMID: 367103]
[4] Jackson, C.M. and Nemerson, Y. Blood coagulation. Annu. Rev. Biochem. 49 (1980) 765–811. [DOI] [PMID: 6996572]
[5] McMullen, B.A., Fujikawa, K., Kisiel, W., Sasagawa, T., Howald, W.N., Kwa, E.Y. and Weinstein, B. Complete amino acid sequence of the light chain of human blood coagulation factor X: evidence for identification of residue 63 as β-hydroxyaspartic acid. Biochemistry 22 (1983) 2875–2884. [PMID: 6871167]
[6] Cho, K., Tanaka, T., Cook, R.R., Kisiel, W., Fujikawa, K., Kurachi, K. and Powers, J.C. Active-site mapping of bovine and human blood coagulation serine proteases using synthetic peptide 4-nitroanilide and thio ester substrates. Biochemistry 23 (1984) 644–650. [PMID: 6370301]

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