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Enzyme - EC 3.4.21.39
DFBP ID DFBPENZY0049
EC Number EC 3.4.21.39
Term Chymase
Introduction
DFBP ID DFBPENZY0049
EC Number EC 3.4.21.39
Accepted Name

Accepted name:
     • Chymase
Alternative name(s):
     • Mast cell protease I
     • Skeletal muscle (SK) protease

Cleavage sites
Number
Pn------
P4
P3
P2
P1
Cleavage sites
P1'
P2'
------Pm'
site.1------
-
--
F
-|---
------
site.2
-------
-
-
Y
-|---
------
site.3
-------
-
-
W
-|--
-
------
site.4
-------
-
-
L
-|--
-
------
Cross-references
Database(s)
ExPASy - ENZYMEEC 3.4.21.39
MEROPS databaseEnzyme ID S01.140
ExplorEnz database
EC 3.4.21.39
Reference(s)
Literature(s)

[1] Woodbury, R.G., Everitt, M. and Neurath, H. Mast cell proteases. Methods Enzymol. 80 (1981) 588–609. [PMID: 7043202]
[2] Powers, J.C., Tanaka, T., Harper, J.W., Minematsu, Y., Barker, L., Lincoln, D., Crumley, K.V., Fraki, J.E., Schechter, N.M., Lazarus, G.G., Nakajima, K., Nakashino, K., Neurath, H. and Woodbury, R.G. Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors. Biochemistry 24 (1985) 2048–2058. [PMID: 3893542]
[3] Johnson, L.A., Moon, K.E. and Eisenberg, M. Purification to homogeneity of the human skin chymotryptic proteinase "chymase". Anal. Biochem. 155 (1986) 358–364. [DOI] [PMID: 2425663]

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