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Enzyme - EC 3.4.21.82
DFBP ID DFBPENZY0053
EC Number EC 3.4.21.82
Term Glutamyl endopeptidase II
Introduction
DFBP ID DFBPENZY0053
EC Number EC 3.4.21.82
Accepted Name

Accepted name:
     • Glutamyl endopeptidase II
Alternative name(s):
     • GluSGP
     • Glutamic acid-specific protease

Cleavage sites
Number
Pn------
P4
P3
P2
P1
Cleavage sites
P1'
P2'
------Pm'
site.1------
-
--
E
-|-V
-
------
site.2
-------
-
-
A
-|-V
-
------
site.3
-------
-
-
E
-|-A
-
------
Cross-references
Database(s)
ExPASy - ENZYMEEC 3.4.21.82
MEROPS databaseEnzyme ID S01.267
ExplorEnz database
EC 3.4.21.82
Reference(s)
Literature(s)

[1] Yoshida, N., Tsuruyama, S., Nagata, K., Hirayama, K., Noda, K. and Makisumi, S. Purification and characterization of an acidic amino acid specific endopeptidase of Streptomyces griseus obtained from a commercial preparation (Pronase). J. Biochem. (Tokyo) 104 (1988) 451–456. [PMID: 3149277]
[2] Komiyama, T., Bigler, T.L., Yoshida, N., Noda, K. and Laskowski, M., Jr. Replacement of P1 Leu18 by Glu18 in the reactive site of turkey ovomucoid third domain converts it into a strong inhibitor of Glu-specific Streptomyces griseus Proteinase (GluSGP). J. Biol. Chem. 266 (1991) 10727–10730. [PMID: 1674942]
[3] Nagata, K., Yoshida, N., Ogata, F., Araki, M. and Noda, K. Subsite mapping of an acidic amino acid-specific endopeptidase from Streptomyces griseus, GluSGP, and protease V8. J. Biochem. (Tokyo) 110 (1991) 859–862. [PMID: 1794975]
[4] Svendsen, I., Jensen, M.R. and Breddam, K. The primary structure of the glutamic acid-specific protease of Streptomyces griseus. FEBS Lett. 292 (1991) 165–167. [DOI] [PMID: 1959600]
[5] Breddam, K. and Meldal, M. Substrate preferences of glutamic-acid-specific endopeptidases assessed by synthetic peptide substrates based on intramolecular fluorescence quenching. Eur. J. Biochem. 206 (1992) 103–107. [DOI] [PMID: 1587264]

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