Enzyme

Enzyme - EC 3.4.21.96

DFBP ID	DFBPENZY0057
EC Number	EC 3.4.21.96
Term	Lactocepin

Introduction

DFBP ID

DFBPENZY0057

EC Number

EC 3.4.21.96

Accepted Name

Extracellular lactococcal proteinase
Lactococcal cell envelope-associated proteinase
Wall-associated serine proteinase

Cleavage sites

Number	Pn------	P4	P3	P2	P1	Cleavage sites	P1'	P2'	------Pm'
site.1	------	-	-	-	Q	-\|-	-	-	------
site.2	------	-	-	-	V	-\|-	-	-	------
site.3	------	-	-	-	-	-\|-	P	-	------
site.4	------	-	-	-	-	-\|-	Q	-	------
site.5	------	-	-	-	P	-\|-	-	-	------
site.6	------	-	-	-	-	-\|-	S	-	------
site.7	------	-	-	-	L	-\|-	-	-	------
site.8	------	-	-	-	-	-\|-	L	-	------

Cross-references

Database(s)

ExPASy - ENZYME	EC 3.4.21.96
MEROPS database	Enzyme ID S08.019
ExplorEnz database	EC 3.4.21.96

Reference(s)

Literature(s)

[1] Visser, S., Robben, A.J.P.M. and Slangen, C.J. Specificity of a cell-envelope-located proteinase (PIII-type) from Lactococcus lactis subsp. cremoris AM1 in its action on bovine β-casein. Appl. Microbiol. Biotechnol. 35 (1991) 477–483. [PMID: 1367552]
[2] Monnet, V., Ley, J.P. and Gonzalez, S. Substrate specificity of the cell envelope-located proteinase of Lactococcus lactis subsp. lactis NCDO763. Int. J. Biochem. 24 (1992) 707–718. [PMID: 1592148]
[3] Exterkate, F.A., Alting, A.C. and Bruinenberg, P.G. Diversity of cell envelope proteinase specificity among strains of Lactococcus lactis and its relationship to charge characteristics of the substrate-binding region. Appl. Environ. Microbiol. 59 (1993) 3640–3647. [PMID: 8285671]
[4] Pritchard, G.G. and Coolbear, T. The physiology and biochemistry of the proteolytic system in lactic acid bacteria. FEMS Microbiol. Rev. 12 (1993) 179–206. [PMID: 8398214]