Target Protein

DFBPID

TPALGL0035

ProteinName

Lysosomal alpha-glucosidase

Function

Essential for the degradation of glygogen to glucose in lysosomes.

TargetGene

Specific Target Gene
Target protein:	Recommended name: • Lysosomal alpha-glucosidase (EC:3.2.1.20) Alternative name(s): • Acid maltase • Aglucosidase alfa Cleaved into the following 2 chains: • 76 kDa lysosomal alpha-glucosidase • 70 kDa lysosomal alpha-glucosidase
Target gene ID:	GAA
Organism of Target:	Homo sapiens (Human)
Taxonomic identifier:	9606 [NCBI]
Target Uniprot ID:	P10253
Target ChEMBL ID:	CHEMBL2608
Target TTD ID:	T31514

Diseases

Diseases associated with this peptide
Glycogen storage disease 2 (GSD2)	See also OMIM:232300

Pathways

Enzyme and pathway databases of target protein
BRENDA	3.2.1.20 2681
Reactome	R-HSA-5357609 Glycogen storage disease type II (GAA) R-HSA-6798695 Neutrophil degranulation R-HSA-70221 Glycogen breakdown (glycogenolysis)

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