Factor IX is a vitamin K-dependent plasma protein
that participates in the intrinsic pathway of blood coagulation by
converting factor X to its active form in the presence of Ca2+ ions, phospholipids, and factor VIIIa.
TargetGene
Specific Target Gene
Target protein:
Recommended name: • Coagulation factor IX ▪ Short-name: FIX Alternative name(s): • Christmas factor • Plasma thromboplastin component ▪ Short-name: PTC • coagulation factor IXa ▪ Short-name: FIXa Cleaved into the following 2 chains: • Coagulation factor IXa light chain • Coagulation factor IXa heavy chain
R-HSA-140834 Extrinsic Pathway of Fibrin Clot Formation R-HSA-140837 Intrinsic Pathway of Fibrin Clot Formation R-HSA-159740 Gamma-carboxylation of protein precursors R-HSA-159763 Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus R-HSA-159782 Removal of aminoterminal propeptides from gamma-carboxylated proteins
