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DFBP database

Target Protein

DFBPID TPANTH0016
ProteinName Coagulation factor XI
Function

Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
TargetGene
Specific Target Gene
Target protein:
Recommended name:
     • Coagulation factor XI (EC:3.4.21.27)
          ▪ Short name: FXI
Alternative name(s):
     • Plasma thromboplastin antecedent
          ▪ Short name: PTA
     • Coagulation factor XIa
          ▪ Short name: FXIa
Cleaved into the following 2 chains:
     • Coagulation factor XIa heavy chain
     • Coagulation factor XIa light chain
Target gene ID:
F11
Organism of Target:
Homo sapiens (Human)
Taxonomic identifier:
9606  [NCBI]
Target Uniprot ID:P03951
Target ChEMBL ID:
CHEMBL2820
Target TTD ID:T15803, T46040
Diseases
Diseases associated with this peptide
Factor XI deficiency (FA11D)See also OMIM:612416
Pathways
Enzyme and pathway databases of target protein
BRENDA3.4.21.27 2681
ReactomeR-HSA-140837 Intrinsic Pathway of Fibrin Clot Formation
Copyright © 2020. Record / license number: Chongqing ICP No. 2000214