Target Protein

DFBPID

TPBRAD0200

ProteinName

B1 bradykinin receptor

Function

This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

TargetGene

Specific Target Gene
Target protein:	Recommended name: • B1 bradykinin receptor ▪ Short name: B1R ▪ Short name: BK-1 receptor
Target gene ID:	BDKRB1
Organism of Target:	Homo sapiens (Human)
Taxonomic identifier:	9606 [NCBI]
Target Uniprot ID:	P46663
Target ChEMBL ID:	CHEMBL4308
Target TTD ID:	T58589

Diseases

Diseases associated with this peptide

Diabetic macular edema [ICD9: 250, 362.01, 362.07, 362.53, 782.3; ICD10: E08-E13, E08.3, E09.3, E10.3, E11.3, E13.3, H35.8, R60.9]

Osteoarthritis [ICD9: 715; ICD10: M15-M19, M47]

Pain [ICD9: 338, 356.0, 356.8,780; ICD10: G64, G90.0, R52, G89]

Rheumatoid arthritis [ICD9: 710-719, 714; ICD10: M05-M06]

Pathways

Enzyme and pathway databases of target protein
Reactome	R-HSA-375276 Peptide ligand-binding receptors R-HSA-416476 G alpha (q) signalling events R-HSA-418594 G alpha (i) signalling events