| Descriptors of SVWG for 20 coded amino acids. |
| AA |
Abbr. |
V1 a |
V2 |
V3 |
V4 |
V5 |
V6 |
V7 |
V8 |
V9 |
V10 |
| Ala |
A |
-11.63440 |
-1.89677 |
1.97792 |
-2.60584 |
-13.32920 |
3.68290 |
2.20150 |
-1.40800 |
1.87320 |
-2.09620 |
| Arg |
R |
11.87107 |
-2.87032 |
2.74823 |
1.25733 |
11.71110 |
8.55360 |
3.61840 |
-2.82840 |
-6.22830 |
-2.32490 |
| Asn |
N |
-5.34951 |
7.68317 |
4.11656 |
4.17370 |
-2.05690 |
-5.91730 |
-2.31410 |
5.18900 |
0.68590 |
-4.40310 |
| Asp |
D |
-4.02676 |
2.99296 |
-3.35851 |
-3.77013 |
-4.68030 |
-2.81900 |
-2.40100 |
5.49000 |
-4.33880 |
-0.34560 |
| Cys |
C |
-5.65032 |
-2.87927 |
-2.99048 |
2.34350 |
-11.29130 |
-13.13940 |
5.36090 |
-6.76210 |
-3.50330 |
2.85190 |
| Gln |
Q |
2.17649 |
-2.40014 |
0.84542 |
3.57161 |
3.14230 |
-0.62880 |
-0.83850 |
3.07280 |
-0.91240 |
-0.33380 |
| Glu |
E |
2.36689 |
0.15236 |
-4.04847 |
0.80392 |
1.28550 |
0.94200 |
-1.29270 |
5.14550 |
-3.63910 |
1.99400 |
| Gly |
G |
-11.78230 |
-13.69750 |
3.47023 |
0.20083 |
-18.81090 |
9.47590 |
8.55280 |
1.77700 |
3.44460 |
2.06590 |
| His |
H |
2.33867 |
0.36099 |
-1.56522 |
-1.07602 |
4.81360 |
-3.65300 |
0.68840 |
4.69490 |
3.20830 |
3.49070 |
| Ile |
I |
0.41167 |
6.40422 |
-1.24429 |
-1.62207 |
2.31450 |
1.24510 |
-9.09730 |
-2.92420 |
0.14050 |
2.94390 |
| Leu |
L |
0.26884 |
8.11636 |
2.89694 |
0.98231 |
4.00210 |
3.13240 |
-6.00550 |
-0.67370 |
3.44850 |
1.78520 |
| Lys |
K |
9.00644 |
-2.09657 |
-3.35485 |
2.39215 |
7.01890 |
7.26380 |
1.31660 |
-1.09820 |
-1.36570 |
1.31620 |
| Met |
M |
4.36305 |
-1.66543 |
-3.97675 |
-1.02332 |
2.52620 |
-3.35200 |
3.12670 |
1.47330 |
1.16900 |
4.42850 |
| Phe |
F |
7.26373 |
-4.36604 |
-1.09058 |
1.62148 |
9.14030 |
-0.49530 |
-0.35650 |
-2.40700 |
4.34140 |
1.28680 |
| Pro |
P |
-5.30690 |
3.18399 |
0.59462 |
4.27735 |
-5.35640 |
-2.59820 |
-1.56580 |
-1.58090 |
4.20020 |
-6.75970 |
| Ser |
S |
-9.15545 |
2.32007 |
-0.49944 |
-2.26929 |
-10.29510 |
0.89680 |
-0.83690 |
0.56780 |
-2.21460 |
-1.32590 |
| Thr |
T |
-4.22009 |
-0.27234 |
-1.39095 |
-2.53752 |
-6.30730 |
1.08710 |
-3.97250 |
-1.85040 |
-3.10140 |
-1.06170 |
| Trp |
W |
11.70248 |
0.16164 |
5.62047 |
-4.91875 |
17.52680 |
-3.13960 |
6.07430 |
-1.21770 |
1.65720 |
-2.24980 |
| Tyr |
Y |
8.54042 |
-1.52583 |
1.74131 |
-1.28473 |
11.88590 |
-1.72920 |
4.54460 |
-0.24250 |
0.26100 |
-1.71890 |
| Val |
V |
-3.18401 |
2.29446 |
-0.49218 |
-0.51649 |
-3.23990 |
1.19220 |
-6.80360 |
-4.41730 |
0.87390 |
0.45660 |
| a The 10 principal component scores are obtained by PCA on 99 WHIM and 197 GETWAY descriptors. |
| References |
[1] J. B. Tong, Y. Chen, S. L. Liu, T. Che, X. M. Xu, A descriptor of amino acids SVWG and its applications in peptide QSAR, J. Chemometr., 26 (2012) 549-555. |
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