Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPACEI0101(ACE-inhibitory peptide)

DFBP ID	DFBPACEI0101
Peptide sequence	WGD
Type	Native peptide
Peptide/Function name	ACE-inhibitory peptide

Function-activity relationship

Main bioactivity	ACE-inhibitory activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

Trp-Gly-Asp

Single-letter amino acid

WGD

Peptide length

Peptide mass

Experimental mass	Theoretical mass
376 Da	376.37 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

3.13 ^c

IC₅₀

+ (data not shown)

pIC₅₀

+ (data not shown)

GRAVY

-1.6000^c

Hydrophilic residue ratio

66.67%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Marine, Fish
Organism/Source	Bonito
Precursor protein	Muscle protein
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR0943 ---- Plant proteins ---- Replication protein A 70 kDa DNA-binding subunit A Source.2: DFBPPR0988 ---- Plant proteins ---- Sucrose synthase 2 Source.3: DFBPPR0989 ---- Plant proteins ---- Calcium-dependent protein kinase 21 Source.4: DFBPPR1114 ---- Plant proteins ---- Pyruvate kinase 1, cytosolic Source.5: DFBPPR1163 ---- Plant proteins ---- Cation-chloride cotransporter 1 Source.6: DFBPPR1183 ---- Plant proteins ---- MADS-box transcription factor 18 Source.7: DFBPPR1318 ---- Plant proteins ---- Calcium-dependent protein kinase 22 Source.8: DFBPPR1421 ---- Plant proteins ---- GDP-mannose 3,5-epimerase 1 Source.9: DFBPPR1456 ---- Plant proteins ---- Syn-copalyl diphosphate synthase Source.10: DFBPPR1481 ---- Plant proteins ---- Leucine-rich repeat receptor protein kinase MSL1 Source.11: DFBPPR1483 ---- Plant proteins ---- Isoamylase 3, chloroplastic Source.12: DFBPPR1507 ---- Plant proteins ---- Very-long-chain aldehyde decarbonylase GL1-4 Source.13: DFBPPR1548 ---- Plant proteins ---- Ent-copalyl diphosphate synthase 1, chloroplastic Source.14: DFBPPR1592 ---- Plant proteins ---- Adenylosuccinate synthetase 1, chloroplastic Source.15: DFBPPR1599 ---- Plant proteins ---- Adenylosuccinate synthetase 2, chloroplastic Source.16: DFBPPR1608 ---- Plant proteins ---- Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 Source.17: DFBPPR1619 ---- Plant proteins ---- Xylanase inhibitor protein 1 Source.18: DFBPPR1637 ---- Plant proteins ---- Ent-copalyl diphosphate synthase 2 Source.19: DFBPPR1697 ---- Plant proteins ---- Probable RNA-dependent RNA polymerase SHL2 Source.20: DFBPPR1734 ---- Plant proteins ---- Probable mixed-linked glucan synthase 9 Source.21: DFBPPR1765 ---- Plant proteins ---- Transcription factor MYC2 Source.22: DFBPPR1816 ---- Plant proteins ---- Transcription factor RF2a Source.23: DFBPPR1892 ---- Plant proteins ---- Sucrose synthase 1 Source.24: DFBPPR1914 ---- Plant proteins ---- Xanthine dehydrogenase Source.25: DFBPPR1943 ---- Plant proteins ---- Naringenin 7-O-methyltransferase Source.26: DFBPPR2084 ---- Plant proteins ---- Pyruvate kinase 2, cytosolic Source.27: DFBPPR2091 ---- Plant proteins ---- Cellulose synthase-like protein D3 Source.28: DFBPPR2162 ---- Plant proteins ---- Very-long-chain aldehyde decarbonylase GL1-7 Source.29: DFBPPR2253 ---- Plant proteins ---- Probable methylenetetrahydrofolate reductase Source.30: DFBPPR2302 ---- Plant proteins ---- Bowman-Birk type bran trypsin inhibitor Source.31: DFBPPR2346 ---- Plant proteins ---- Probable tocopherol cyclase, chloroplastic Source.32: DFBPPR2355 ---- Plant proteins ---- Probable glycosyltransferase 5 Source.33: DFBPPR2394 ---- Plant proteins ---- Sucrose synthase 5 Source.34: DFBPPR2536 ---- Plant proteins ---- Heat stress transcription factor B-4c Source.35: DFBPPR2615 ---- Plant proteins ---- Cytochrome P450 734A5 Source.36: DFBPPR2650 ---- Plant proteins ---- mRNA cap guanine-N7 methyltransferase 2 Source.37: DFBPPR2682 ---- Plant proteins ---- Beta-glucosidase 30 Source.38: DFBPPR2702 ---- Plant proteins ---- Beta-glucosidase 27 Source.39: DFBPPR2734 ---- Plant proteins ---- Cation-chloride cotransporter 2 Source.40: DFBPPR2804 ---- Plant proteins ---- Protein GIGANTEA Source.41: DFBPPR2885 ---- Plant proteins ---- Ammonium transporter 2 member 1 Source.42: DFBPPR2891 ---- Plant proteins ---- GDP-mannose 3,5-epimerase 2 Source.43: DFBPPR2955 ---- Plant proteins ---- Probable protein arginine N-methyltransferase 3 Source.44: DFBPPR2967 ---- Plant proteins ---- Sucrose synthase 7 Source.45: DFBPPR3039 ---- Plant proteins ---- Probable auxin efflux carrier component 5b Source.46: DFBPPR3078 ---- Plant proteins ---- Transcription factor TGAL3 Source.47: DFBPPR3173 ---- Plant proteins ---- Beta-glucosidase 29 Source.48: DFBPPR3227 ---- Plant proteins ---- Oryzain gamma chain Source.49: DFBPPR3230 ---- Plant proteins ---- Probable protein phosphatase 2C 37 Source.50: DFBPPR3237 ---- Plant proteins ---- Arginine decarboxylase 2 Source.51: DFBPPR3266 ---- Plant proteins ---- Protein MOR1 Source.52: DFBPPR3282 ---- Plant proteins ---- Putative beta-glucosidase 35 Source.53: DFBPPR3314 ---- Plant proteins ---- Probable auxin efflux carrier component 5a Source.54: DFBPPR3402 ---- Plant proteins ---- Probable auxin efflux carrier component 5c Source.55: DFBPPR3450 ---- Plant proteins ---- Disease resistance protein RGA5 Source.56: DFBPPR3490 ---- Plant proteins ---- WUSCHEL-related homeobox 4 Source.57: DFBPPR3541 ---- Plant proteins ---- Sucrose synthase 3 Source.58: DFBPPR3580 ---- Plant proteins ---- Ribosome biogenesis protein BOP1 homolog Source.59: DFBPPR3602 ---- Plant proteins ---- Coatomer subunit alpha-2 Source.60: DFBPPR3714 ---- Plant proteins ---- GDT1-like protein 4 Source.61: DFBPPR3719 ---- Plant proteins ---- GDT1-like protein 5 Source.62: DFBPPR3822 ---- Plant proteins ---- Coatomer subunit alpha-3 Source.63: DFBPPR3928 ---- Plant proteins ---- Coatomer subunit alpha-1 Source.64: DFBPPR3935 ---- Plant proteins ---- Sucrose synthase 4 Source.65: DFBPPR3946 ---- Plant proteins ---- Transcription factor TGAL10 Source.66: DFBPPR3963 ---- Plant proteins ---- Squamosa promoter-binding-like protein 9 Source.67: DFBPPR4015 ---- Plant proteins ---- GDT1-like protein 3 Source.68: DFBPPR4186 ---- Plant proteins ---- Formin-like protein 18 Source.69: DFBPPR4229 ---- Plant proteins ---- GDT1-like protein 1, chloroplastic Source.70: DFBPPR4247 ---- Plant proteins ---- GDT1-like protein 2, chloroplastic Source.71: DFBPPR4380 ---- Plant proteins ---- Sucrose synthase 6 Source.72: DFBPPR4411 ---- Plant proteins ---- Ammonium transporter 2 member 2 Source.73: DFBPPR4437 ---- Plant proteins ---- Ricin B-like lectin R40C1 Source.74: DFBPPR4462 ---- Plant proteins ---- Ammonium transporter 2 member 3 Source.75: DFBPPR4478 ---- Plant proteins ---- Ammonium transporter 3 member 1 Source.76: DFBPPR4492 ---- Plant proteins ---- Ammonium transporter 3 member 2 Source.77: DFBPPR4507 ---- Plant proteins ---- Protein WHAT'S THIS FACTOR 1 homolog, chloroplastic Source.78: DFBPPR4632 ---- Plant proteins ---- Putative ammonium transporter 4 member 1 Source.79: DFBPPR4657 ---- Plant proteins ---- Probable plastid-lipid-associated protein 3, chloroplastic Source.80: DFBPPR4693 ---- Plant proteins ---- Uncharacterized protein ycf68 Source.81: DFBPPR4713 ---- Plant proteins ---- Zinc finger CCCH domain-containing protein 14 Source.82: DFBPPR4895 ---- Plant proteins ---- Carotenoid cleavage dioxygenase 7, chloroplastic Source.83: DFBPPR4901 ---- Plant proteins ---- Serine/threonine-protein kinase-like protein CR4 Source.84: DFBPPR4912 ---- Plant proteins ---- Probable xyloglucan 6-xylosyltransferase 1 Source.85: DFBPPR5056 ---- Plant proteins ---- Sucrose synthase Source.86: DFBPPR5379 ---- Plant proteins ---- (E)-beta-farnesene synthase Source.87: DFBPPR5383 ---- Plant proteins ---- (E)-beta-caryophyllene synthase Source.88: DFBPPR5386 ---- Plant proteins ---- (S)-beta-macrocarpene synthase Source.89: DFBPPR5388 ---- Plant proteins ---- (S)-beta-macrocarpene synthase Source.90: DFBPPR5397 ---- Plant proteins ---- Alpha-terpineol synthase, chloroplastic Source.91: DFBPPR5413 ---- Plant proteins ---- Putative receptor protein kinase CRINKLY4 Source.92: DFBPPR5415 ---- Plant proteins ---- Eudesmanediol synthase Source.93: DFBPPR5438 ---- Plant proteins ---- Tau-cadinol synthase Source.94: DFBPPR5463 ---- Plant proteins ---- Ent-copalyl diphosphate synthase AN2, chloroplastic Source.95: DFBPPR5470 ---- Plant proteins ---- Ent-copalyl diphosphate synthase AN1, chloroplastic Source.96: DFBPPR5519 ---- Plant proteins ---- Beta-selinene synthase Source.97: DFBPPR5547 ---- Plant proteins ---- Methylenetetrahydrofolate reductase 1 Source.98: DFBPPR5573 ---- Plant proteins ---- Dolabradiene monooxygenase Source.99: DFBPPR5574 ---- Plant proteins ---- Protein WHAT'S THIS FACTOR 1, chloroplastic Source.100: DFBPPR5581 ---- Plant proteins ---- Adenylosuccinate synthetase, chloroplastic Source.101: DFBPPR5634 ---- Plant proteins ---- Eudesmanediol synthase Source.102: DFBPPR5785 ---- Plant proteins ---- (E)-beta-caryophyllene synthase Source.103: DFBPPR5852 ---- Plant proteins ---- Sucrose synthase 2 Source.104: DFBPPR5857 ---- Plant proteins ---- Sucrose synthase 1 Source.105: DFBPPR5907 ---- Plant proteins ---- Probable DNA-directed RNA polymerase Source.106: DFBPPR6018 ---- Plant proteins ---- Probable tocopherol cyclase, chloroplastic Source.107: DFBPPR6062 ---- Plant proteins ---- HSP-interacting protein Source.108: DFBPPR6151 ---- Plant proteins ---- Uncharacterized protein ycf68 Source.109: DFBPPR6181 ---- Plant proteins ---- Unknown protein from spot 154 of 2D-PAGE of etiolated coleoptile Source.110: DFBPPR6208 ---- Plant proteins ---- Cysteine proteinase 2 Source.111: DFBPPR6247 ---- Plant proteins ---- DNA topoisomerase 2 Source.112: DFBPPR6342 ---- Plant proteins ---- Ent-copalyl diphosphate synthase, chloroplastic Source.113: DFBPPR6487 ---- Plant proteins ---- Basic helix-loop-helix protein A Source.114: DFBPPR6506 ---- Plant proteins ---- Sucrose synthase 2 Source.115: DFBPPR6559 ---- Plant proteins ---- Truncated basic helix-loop-helix protein A Source.116: DFBPPR6675 ---- Plant proteins ---- Adenylosuccinate synthetase, chloroplastic Source.117: DFBPPR7101 ---- Plant proteins ---- Sucrose synthase 1 Source.118: DFBPPR7106 ---- Plant proteins ---- Sucrose synthase 2 Source.119: DFBPPR7140 ---- Plant proteins ---- Glutamate--tRNA ligase, chloroplastic/mitochondrial Source.120: DFBPPR7204 ---- Plant proteins ---- Thiol protease aleurain Source.121: DFBPPR7214 ---- Plant proteins ---- Alpha-glucosidase Source.122: DFBPPR7279 ---- Plant proteins ---- 60 kDa jasmonate-induced protein Source.123: DFBPPR7404 ---- Plant proteins ---- O-fucosyltransferase 20 Source.124: DFBPPR7636 ---- Milk proteins ---- Suppressor of tumorigenicity 14 protein Source.125: DFBPPR15949 ---- Animal proteins ---- Potassium voltage-gated channel subfamily H member 2 Source.126: DFBPPR15957 ---- Animal proteins ---- Prostaglandin G/H synthase 1 Source.127: DFBPPR16049 ---- Animal proteins ---- Cytochrome P450 1A2 Source.128: DFBPPR16050 ---- Animal proteins ---- Dual oxidase 1 Source.129: DFBPPR16053 ---- Animal proteins ---- Glyceraldehyde-3-phosphate dehydrogenase Source.130: DFBPPR16076 ---- Animal proteins ---- Gap junction alpha-5 protein Source.131: DFBPPR16094 ---- Animal proteins ---- Mastin Source.132: DFBPPR16135 ---- Animal proteins ---- Gap junction alpha-1 protein Source.133: DFBPPR16153 ---- Animal proteins ---- Death domain-associated protein 6 Source.134: DFBPPR16201 ---- Animal proteins ---- X-linked retinitis pigmentosa GTPase regulator Source.135: DFBPPR16436 ---- Animal proteins ---- Glycogen debranching enzyme Source.136: DFBPPR16521 ---- Animal proteins ---- Interleukin-3 Source.137: DFBPPR16523 ---- Animal proteins ---- Hepatocyte growth factor activator Source.138: DFBPPR16626 ---- Animal proteins ---- RING finger protein unkempt homolog Source.139: DFBPPR16810 ---- Animal proteins ---- Cathepsin B Source.140: DFBPPR17078 ---- Animal proteins ---- Prostaglandin G/H synthase 2 Source.141: DFBPPR17119 ---- Animal proteins ---- Hyaluronidase-2 Source.142: DFBPPR17172 ---- Animal proteins ---- Cartilage oligomeric matrix protein Source.143: DFBPPR17297 ---- Animal proteins ---- Glyceraldehyde-3-phosphate dehydrogenase Source.144: DFBPPR17303 ---- Animal proteins ---- Phosphatidylinositol 3-kinase regulatory subunit alpha Source.145: DFBPPR17394 ---- Animal proteins ---- Diacylglycerol kinase alpha Source.146: DFBPPR17404 ---- Animal proteins ---- Lysophosphatidylserine lipase ABHD12 Source.147: DFBPPR17448 ---- Animal proteins ---- Gap junction alpha-1 protein Source.148: DFBPPR17498 ---- Animal proteins ---- Guanine nucleotide-binding protein G(o) subunit alpha Source.149: DFBPPR17511 ---- Animal proteins ---- Prostaglandin G/H synthase 1 Source.150: DFBPPR17575 ---- Animal proteins ---- A disintegrin and metalloproteinase with thrombospondin motifs 4 Source.151: DFBPPR17576 ---- Animal proteins ---- Fibrillin-1 Source.152: DFBPPR17610 ---- Animal proteins ---- Cytochrome c oxidase subunit 6A2, mitochondrial Source.153: DFBPPR17660 ---- Animal proteins ---- 5'-AMP-activated protein kinase subunit gamma-3 Source.154: DFBPPR17691 ---- Animal proteins ---- Integrin alpha-L Source.155: DFBPPR17693 ---- Animal proteins ---- Carnitine O-palmitoyltransferase 2, mitochondrial Source.156: DFBPPR17864 ---- Animal proteins ---- ATP-citrate synthase Source.157: DFBPPR17900 ---- Animal proteins ---- Acetyl-CoA carboxylase 1 Source.158: DFBPPR17984 ---- Animal proteins ---- Phosphatidylinositol 3-kinase regulatory subunit beta Source.159: DFBPPR18003 ---- Animal proteins ---- 7-dehydrocholesterol reductase Source.160: DFBPPR18070 ---- Animal proteins ---- Serine--tRNA ligase, cytoplasmic Source.161: DFBPPR18128 ---- Animal proteins ---- Gap junction alpha-3 protein Source.162: DFBPPR18194 ---- Animal proteins ---- Synapse differentiation-inducing gene protein 1 Source.163: DFBPPR18236 ---- Animal proteins ---- Latent-transforming growth factor beta-binding protein 2 Source.164: DFBPPR18255 ---- Animal proteins ---- Adenylosuccinate synthetase isozyme 2 Source.165: DFBPPR18369 ---- Animal proteins ---- Ribosomal oxygenase 1 Source.166: DFBPPR18444 ---- Animal proteins ---- Beta-1 adrenergic receptor Source.167: DFBPPR18474 ---- Animal proteins ---- Peroxisomal carnitine O-octanoyltransferase Source.168: DFBPPR18476 ---- Animal proteins ---- Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 Source.169: DFBPPR18515 ---- Animal proteins ---- cAMP-dependent protein kinase type II-beta regulatory subunit Source.170: DFBPPR18734 ---- Animal proteins ---- E3 ubiquitin-protein ligase RNF114 Source.171: DFBPPR18876 ---- Animal proteins ---- Adenylosuccinate synthetase isozyme 1 Source.172: DFBPPR19011 ---- Animal proteins ---- E3 ubiquitin-protein ligase RNF138 Source.173: DFBPPR19036 ---- Animal proteins ---- Elongation factor 2 Source.174: DFBPPR19241 ---- Animal proteins ---- Gap junction beta-1 protein Source.175: DFBPPR19259 ---- Animal proteins ---- Protein transport protein Sec16B Source.176: DFBPPR19272 ---- Animal proteins ---- Ribosomal oxygenase 2 Source.177: DFBPPR19373 ---- Animal proteins ---- 116 kDa U5 small nuclear ribonucleoprotein component Source.178: DFBPPR19412 ---- Animal proteins ---- N-terminal kinase-like protein Source.179: DFBPPR19438 ---- Animal proteins ---- Protein Mis18-alpha Source.180: DFBPPR19538 ---- Animal proteins ---- Cytochrome c oxidase subunit 6A1, mitochondrial Source.181: DFBPPR19579 ---- Animal proteins ---- Sodium- and chloride-dependent GABA transporter 2 Source.182: DFBPPR19672 ---- Animal proteins ---- Gap junction beta-6 protein Source.183: DFBPPR19704 ---- Animal proteins ---- Vacuolar protein sorting-associated protein 29 Source.184: DFBPPR19870 ---- Animal proteins ---- CCAAT/enhancer-binding protein delta Source.185: DFBPPR19938 ---- Animal proteins ---- Serine/threonine-protein phosphatase CPPED1 Source.186: DFBPPR19952 ---- Animal proteins ---- Cell surface glycoprotein CD200 receptor 1 Source.187: DFBPPR19957 ---- Animal proteins ---- Gap junction beta-2 protein Source.188: DFBPPR20029 ---- Animal proteins ---- Sodium- and chloride-dependent glycine transporter 1 Source.189: DFBPPR20069 ---- Animal proteins ---- Glycogen [starch] synthase, muscle Source.190: DFBPPR20163 ---- Animal proteins ---- Lymphocyte antigen 6 complex locus protein G6f Source.191: DFBPPR20378 ---- Animal proteins ---- GPI mannosyltransferase 1 Source.192: DFBPPR20407 ---- Animal proteins ---- Phosphatidylinositol 3-kinase regulatory subunit gamma Source.193: DFBPPR20540 ---- Animal proteins ---- Structure-specific endonuclease subunit SLX1 Source.194: DFBPPR20656 ---- Animal proteins ---- Protein archease Source.195: DFBPPR20663 ---- Animal proteins ---- Gap junction beta-3 protein Source.196: DFBPPR20673 ---- Animal proteins ---- Trafficking protein particle complex subunit 9 Source.197: DFBPPR20701 ---- Animal proteins ---- Cysteine--tRNA ligase, mitochondrial Source.198: DFBPPR20839 ---- Animal proteins ---- Cysteine-rich secretory protein LCCL domain-containing 2 Source.199: DFBPPR20963 ---- Animal proteins ---- Protein kintoun Source.200: DFBPPR21163 ---- Animal proteins ---- Uridine diphosphate glucose pyrophosphatase NUDT22 Source.201: DFBPPR21229 ---- Animal proteins ---- Neurexophilin-2 Source.202: DFBPPR21248 ---- Animal proteins ---- 39S ribosomal protein L4, mitochondrial Source.203: DFBPPR21278 ---- Animal proteins ---- Adaptin ear-binding coat-associated protein 2 Source.204: DFBPPR21305 ---- Animal proteins ---- Methyltransferase-like protein 17, mitochondrial Source.205: DFBPPR21317 ---- Animal proteins ---- Gap junction alpha-4 protein Source.206: DFBPPR21411 ---- Animal proteins ---- Adaptin ear-binding coat-associated protein 1 Source.207: DFBPPR21471 ---- Animal proteins ---- Gap junction alpha-5 protein Source.208: DFBPPR21639 ---- Animal proteins ---- Elongator complex protein 4 Source.209: DFBPPR21898 ---- Animal proteins ---- Junctional sarcoplasmic reticulum protein 1 Source.210: DFBPPR21942 ---- Animal proteins ---- Neurexophilin-1 Source.211: DFBPPR22069 ---- Animal proteins ---- Retrotransposon-like protein 1 Source.212: DFBPPR22358 ---- Animal proteins ---- Dynein assembly factor 3, axonemal Source.213: DFBPPR22648 ---- Animal proteins ---- Ankyrin repeat domain-containing protein 65 Source.214: DFBPPR22686 ---- Animal proteins ---- Vertnin Source.215: DFBPPR8597 ---- Animal proteins ---- Diacylglycerol kinase alpha Source.216: DFBPPR8663 ---- Animal proteins ---- Glyceraldehyde-3-phosphate dehydrogenase Source.217: DFBPPR8748 ---- Animal proteins ---- Dual oxidase 2 Source.218: DFBPPR8754 ---- Animal proteins ---- Dual oxidase 1 Source.219: DFBPPR8757 ---- Animal proteins ---- Gap junction alpha-1 protein Source.220: DFBPPR8780 ---- Animal proteins ---- ATP-dependent 6-phosphofructokinase, muscle type Source.221: DFBPPR8942 ---- Animal proteins ---- Adenylosuccinate synthetase isozyme 2 Source.222: DFBPPR8945 ---- Animal proteins ---- Coagulation factor V Source.223: DFBPPR8971 ---- Animal proteins ---- Fibrillin-1 Source.224: DFBPPR8992 ---- Animal proteins ---- Hyaluronidase-3 Source.225: DFBPPR9116 ---- Animal proteins ---- Cathepsin B Source.226: DFBPPR9201 ---- Animal proteins ---- Adenylosuccinate synthetase isozyme 1 Source.227: DFBPPR9404 ---- Animal proteins ---- Tryptase Source.228: DFBPPR9418 ---- Animal proteins ---- N-acetylgalactosamine-6-sulfatase Source.229: DFBPPR9548 ---- Animal proteins ---- Membrane progestin receptor alpha Source.230: DFBPPR9558 ---- Animal proteins ---- Gap junction alpha-4 protein Source.231: DFBPPR9897 ---- Animal proteins ---- Negative elongation factor D Source.232: DFBPPR9948 ---- Animal proteins ---- Vertnin Source.233: DFBPPR9954 ---- Animal proteins ---- Tolloid-like protein 1 Source.234: DFBPPR10021 ---- Animal proteins ---- NT-3 growth factor receptor Source.235: DFBPPR10036 ---- Animal proteins ---- Acetyl-CoA carboxylase Source.236: DFBPPR10101 ---- Animal proteins ---- Lysophosphatidylserine lipase ABHD12 Source.237: DFBPPR10133 ---- Animal proteins ---- Gap junction alpha-8 protein Source.238: DFBPPR10236 ---- Animal proteins ---- Acid-sensing ion channel 1 Source.239: DFBPPR10423 ---- Animal proteins ---- Sortilin-related receptor Source.240: DFBPPR10475 ---- Animal proteins ---- Adenylate cyclase type 9 Source.241: DFBPPR10634 ---- Animal proteins ---- Procathepsin L Source.242: DFBPPR10659 ---- Animal proteins ---- Low-density lipoprotein receptor-related protein 8 Source.243: DFBPPR10698 ---- Animal proteins ---- Adenylosuccinate synthetase isozyme 2 Source.244: DFBPPR10699 ---- Animal proteins ---- Acetylcholinesterase Source.245: DFBPPR10846 ---- Animal proteins ---- Gap junction alpha-3 protein Source.246: DFBPPR10869 ---- Animal proteins ---- Ribosomal oxygenase 1 Source.247: DFBPPR10937 ---- Animal proteins ---- Urokinase-type plasminogen activator Source.248: DFBPPR10980 ---- Animal proteins ---- Elongation factor 2 Source.249: DFBPPR11024 ---- Animal proteins ---- Gap junction alpha-1 protein Source.250: DFBPPR11172 ---- Animal proteins ---- Protein transport protein Sec16B Source.251: DFBPPR11216 ---- Animal proteins ---- Gap junction alpha-5 protein Source.252: DFBPPR11231 ---- Animal proteins ---- 116 kDa U5 small nuclear ribonucleoprotein component Source.253: DFBPPR11286 ---- Animal proteins ---- Protein wntless homolog Source.254: DFBPPR11358 ---- Animal proteins ---- Lysozyme g Source.255: DFBPPR11524 ---- Animal proteins ---- E3 ubiquitin-protein ligase RNF166 Source.256: DFBPPR11528 ---- Animal proteins ---- Vacuolar protein sorting-associated protein 29 Source.257: DFBPPR11531 ---- Animal proteins ---- Protein AATF Source.258: DFBPPR11591 ---- Animal proteins ---- Gap junction beta-6 protein Source.259: DFBPPR11605 ---- Animal proteins ---- DNA repair protein complementing XP-A cells homolog Source.260: DFBPPR11622 ---- Animal proteins ---- Ammonium transporter Rh type C Source.261: DFBPPR11654 ---- Animal proteins ---- NADH-ubiquinone oxidoreductase chain 6 Source.262: DFBPPR11671 ---- Animal proteins ---- Glucoside xylosyltransferase 1 Source.263: DFBPPR11699 ---- Animal proteins ---- NEDD8-activating enzyme E1 regulatory subunit Source.264: DFBPPR12238 ---- Animal proteins ---- Programmed cell death protein 2-like Source.265: DFBPPR12254 ---- Animal proteins ---- Cytochrome P450 1A2 Source.266: DFBPPR12282 ---- Animal proteins ---- Cytochrome P450 1A1 Source.267: DFBPPR12287 ---- Animal proteins ---- Glyceraldehyde-3-phosphate dehydrogenase Source.268: DFBPPR12374 ---- Animal proteins ---- Sortilin-related receptor Source.269: DFBPPR12399 ---- Animal proteins ---- Gap junction alpha-1 protein Source.270: DFBPPR12409 ---- Animal proteins ---- Glycogen [starch] synthase, muscle Source.271: DFBPPR12460 ---- Animal proteins ---- ATP-dependent 6-phosphofructokinase, platelet type Source.272: DFBPPR12513 ---- Animal proteins ---- Serine--tRNA ligase, cytoplasmic Source.273: DFBPPR12531 ---- Animal proteins ---- Solute carrier family 12 member 4 Source.274: DFBPPR12555 ---- Animal proteins ---- Glycogen debranching enzyme Source.275: DFBPPR12568 ---- Animal proteins ---- Potassium voltage-gated channel subfamily H member 2 Source.276: DFBPPR12752 ---- Animal proteins ---- Complement component C8 beta chain Source.277: DFBPPR12769 ---- Animal proteins ---- Short transient receptor potential channel 5 Source.278: DFBPPR12855 ---- Animal proteins ---- Solute carrier family 12 member 7 Source.279: DFBPPR12870 ---- Animal proteins ---- Protein transport protein Sec16B Source.280: DFBPPR12983 ---- Animal proteins ---- Cytochrome c oxidase subunit 6A1, mitochondrial Source.281: DFBPPR13268 ---- Animal proteins ---- Glycogen debranching enzyme Source.282: DFBPPR13382 ---- Animal proteins ---- Gap junction beta-1 protein Source.283: DFBPPR13421 ---- Animal proteins ---- Tumor necrosis factor Source.284: DFBPPR13532 ---- Animal proteins ---- Prostaglandin G/H synthase 1 Source.285: DFBPPR13536 ---- Animal proteins ---- Hyaluronidase-2 Source.286: DFBPPR13558 ---- Animal proteins ---- Prostaglandin G/H synthase 2 Source.287: DFBPPR13570 ---- Animal proteins ---- Gap junction alpha-8 protein Source.288: DFBPPR13573 ---- Animal proteins ---- Tumor necrosis factor Source.289: DFBPPR13589 ---- Animal proteins ---- Glyceraldehyde-3-phosphate dehydrogenase Source.290: DFBPPR13590 ---- Animal proteins ---- Gap junction alpha-3 protein Source.291: DFBPPR13601 ---- Animal proteins ---- Cathepsin B Source.292: DFBPPR13603 ---- Animal proteins ---- Acetyl-CoA carboxylase 1 Source.293: DFBPPR13622 ---- Animal proteins ---- ATP-citrate synthase Source.294: DFBPPR13684 ---- Animal proteins ---- Beta-1 adrenergic receptor Source.295: DFBPPR13761 ---- Animal proteins ---- Gap junction beta-2 protein Source.296: DFBPPR13789 ---- Animal proteins ---- Tryptase-2 Source.297: DFBPPR13917 ---- Animal proteins ---- CCAAT/enhancer-binding protein delta Source.298: DFBPPR13994 ---- Animal proteins ---- Receptor-type tyrosine-protein phosphatase C Source.299: DFBPPR14041 ---- Animal proteins ---- NADH-ubiquinone oxidoreductase chain 3 Source.300: DFBPPR14047 ---- Animal proteins ---- Cytochrome c oxidase subunit 6A, mitochondrial Source.301: DFBPPR14092 ---- Marine protein ---- Adenylosuccinate synthetase isozyme 1 B Source.302: DFBPPR14094 ---- Marine protein ---- Adenylosuccinate synthetase isozyme 1 C Source.303: DFBPPR14101 ---- Marine protein ---- Adenylosuccinate synthetase isozyme 1 A Source.304: DFBPPR14158 ---- Marine protein ---- NADH-ubiquinone oxidoreductase chain 3 Source.305: DFBPPR14160 ---- Marine protein ---- NADH-ubiquinone oxidoreductase chain 6 Source.306: DFBPPR14252 ---- Marine protein ---- NADH-ubiquinone oxidoreductase chain 3 Source.307: DFBPPR14328 ---- Marine protein ---- Sulfate adenylyltransferase Source.308: DFBPPR14462 ---- Marine protein ---- Chromophore lyase CpcS/CpeS homolog Source.309: DFBPPR14486 ---- Marine protein ---- Putative transport permease ycf38 Source.310: DFBPPR14657 ---- Marine protein ---- NADH-ubiquinone oxidoreductase chain 4 Source.311: DFBPPR14672 ---- Marine protein ---- NADH-ubiquinone oxidoreductase chain 3 Source.312: DFBPPR14678 ---- Marine protein ---- NADH-ubiquinone oxidoreductase chain 6 Source.313: DFBPPR14683 ---- Marine protein ---- Ammonium transporter Rh type C Source.314: DFBPPR14686 ---- Marine protein ---- Cytochrome c oxidase subunit 6A, mitochondrial Source.315: DFBPPR14753 ---- Marine protein ---- Clotting factor B Source.316: DFBPPR14816 ---- Marine protein ---- Digestive cysteine proteinase 3 Source.317: DFBPPR14819 ---- Marine protein ---- Digestive cysteine proteinase 2 Source.318: DFBPPR14928 ---- Microorganism protein ---- Adenylosuccinate synthetase Source.319: DFBPPR15010 ---- Microorganism protein ---- N-acetyltransferase ECO1 Source.320: DFBPPR15190 ---- Microorganism protein ---- Pescadillo homolog Source.321: DFBPPR15255 ---- Microorganism protein ---- Ribosome biogenesis protein ERB1 Source.322: DFBPPR15266 ---- Microorganism protein ---- Phosphatidylethanolamine N-methyltransferase Source.323: DFBPPR15288 ---- Microorganism protein ---- Serine/threonine-protein phosphatase 2A activator 2 Source.324: DFBPPR15310 ---- Microorganism protein ---- pH-response regulator protein palH/RIM21 Source.325: DFBPPR15352 ---- Microorganism protein ---- Cytosolic Fe-S cluster assembly factor CFD1 Source.326: DFBPPR15434 ---- Microorganism protein ---- pH-response transcription factor pacC/RIM101 Source.327: DFBPPR15483 ---- Microorganism protein ---- Elongation factor 2 Source.328: DFBPPR15615 ---- Microorganism protein ---- Probable transporter MCH1 Source.329: DFBPPR15685 ---- Microorganism protein ---- Zinc-regulated protein 8 Source.330: DFBPPR15753 ---- Microorganism protein ---- KNR4/SMI1 homolog Source.331: DFBPPR15846 ---- Microorganism protein ---- Exoglucanase 3 Source.332: DFBPPR7759 ---- Plant protein ---- Eugenol O-methyltransferase Source.333: DFBPPR7763 ---- Plant protein ---- Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 Source.334: DFBPPR7764 ---- Plant protein ---- Zingiberene synthase Source.335: DFBPPR7767 ---- Plant protein ---- Adenylosuccinate synthetase 2, chloroplastic Source.336: DFBPPR7770 ---- Plant protein ---- Adenylosuccinate synthetase 1, chloroplastic Source.337: DFBPPR7776 ---- Plant protein ---- Beta-sesquiphellandrene synthase Source.338: DFBPPR7934 ---- Plant protein ---- Acid beta-fructofuranosidase Source.339: DFBPPR7964 ---- Plant protein ---- Sucrose synthase Source.340: DFBPPR8047 ---- Plant protein ---- Acid beta-fructofuranosidase Source.341: DFBPPR8213 ---- Plant protein ---- Alpha-copaene synthase Source.342: DFBPPR8222 ---- Plant protein ---- Germacrene A synthase 1 Source.343: DFBPPR8223 ---- Plant protein ---- Germacrene A synthase 2
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

ACE-inhibitory activity	The peptide exhibited Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) inhibitory activity (data not shown).
Specific target protein(s)	Specific Target Protein(s): Angiotensin-converting enzyme

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Non-bitter taste ^prediction

SMILES

N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)NCC(=O)N[C@@]([H])(CC(=O)O)C(=O)O

Preparation method

Mode of preparation	Enzymatic hydrolysis
Enzyme(s)/starter culture	Peptides were digested in 50 mM sodium phosphate buffer (pH 7.8) containing 50-400 ug/ml of trypsin and/or 50-500 ug/ml of chymotrypsin for 2-12 h at 37 ℃.

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Hasan, F., Kumada, Y., Hashimoto, N., Katsuda, T., Terashima, M., Katoh, S. Fragmentation of Angiotensin-I Converting Enzyme Inhibitory Peptides from Bonito Meat Under Intestinal Digestion Conditions and their Characterization. Food and Bioproducts Processing. 2006, 84, 135-8. DOI: 10.1205/fbp.05152
Other literature(s)	[1] Fida H M. ACE Inhibitory Activity and Characteristics of Tri-Peptides Obtained from Bonito Protein[J]. Journal of Chemical Engineering of Japan, 2007, 40(1):59-62. [2] Hasan F, Kumada Y, Hashimoto N, et al. Fragmentation of angiotensin-I converting enzyme inhibitory peptides from bonito meat under intestinal digestion conditions and their characterization.[J]. Food (&) Bioproducts Processing, 2006, 84(2):135-138. [3] Kohama Y, Matsumoto S, Oka H, et al. Isolation of angiotensin-converting enzyme inhibitor from tuna muscle.[J]. Biochemical (&) Biophysical Research Communications, 1988, 155(1):332-7.
PubDate	2006