Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPACEI1534(ACE-inhibitory peptide)

DFBP ID	DFBPACEI1534
Peptide sequence	HHT
Type	Native peptide
Peptide/Function name	ACE-inhibitory peptide

Function-activity relationship

Main bioactivity	ACE-inhibitory activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

His-His-Thr

Single-letter amino acid

HHT

Peptide length

Peptide mass

Experimental mass	Theoretical mass
N.D	393.41 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

7.95 ^c

IC₅₀

800 uM

pIC₅₀

-2.903

GRAVY

-2.3667^c

Hydrophilic residue ratio

0%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Marine, Fish
Organism/Source	Dried bonito (Katsuobusi)
Precursor protein	Muscle protein
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR0838 ---- Plant proteins ---- Glucose-1-phosphate adenylyltransferase large subunit 2, cytosolic Source.2: DFBPPR0889 ---- Plant proteins ---- E3 ubiquitin-protein ligase SPL11 Source.3: DFBPPR0921 ---- Plant proteins ---- Very-long-chain aldehyde decarbonylase GL1-5 Source.4: DFBPPR0939 ---- Plant proteins ---- Protein argonaute MEL1 Source.5: DFBPPR0965 ---- Plant proteins ---- Abscisic acid receptor PYL9 Source.6: DFBPPR1169 ---- Plant proteins ---- Phototropin-1A Source.7: DFBPPR1336 ---- Plant proteins ---- Protein argonaute 7 Source.8: DFBPPR1345 ---- Plant proteins ---- Cadmium/zinc-transporting ATPase HMA2 Source.9: DFBPPR1346 ---- Plant proteins ---- Inositol-tetrakisphosphate 1-kinase 5 Source.10: DFBPPR1370 ---- Plant proteins ---- Phototropin-1B Source.11: DFBPPR1442 ---- Plant proteins ---- Protein SCARECROW 1 Source.12: DFBPPR1475 ---- Plant proteins ---- Glutamate receptor 3.1 Source.13: DFBPPR1498 ---- Plant proteins ---- Protein SCARECROW 2 Source.14: DFBPPR1507 ---- Plant proteins ---- Very-long-chain aldehyde decarbonylase GL1-4 Source.15: DFBPPR1542 ---- Plant proteins ---- Very-long-chain aldehyde decarbonylase GL1-1 Source.16: DFBPPR1567 ---- Plant proteins ---- Protein argonaute PNH1 Source.17: DFBPPR1577 ---- Plant proteins ---- Very-long-chain aldehyde decarbonylase GL1-6 Source.18: DFBPPR1605 ---- Plant proteins ---- Phytochrome B Source.19: DFBPPR1614 ---- Plant proteins ---- Bisdemethoxycurcumin synthase Source.20: DFBPPR1744 ---- Plant proteins ---- Heat stress transcription factor A-1 Source.21: DFBPPR1759 ---- Plant proteins ---- Endoribonuclease Dicer homolog 2a Source.22: DFBPPR1802 ---- Plant proteins ---- Flavonoid 3'-monooxygenase CYP75B3 Source.23: DFBPPR1871 ---- Plant proteins ---- DEAD-box ATP-dependent RNA helicase 17 Source.24: DFBPPR1889 ---- Plant proteins ---- Laccase-18 Source.25: DFBPPR1904 ---- Plant proteins ---- Alanine--tRNA ligase, chloroplastic/mitochondrial Source.26: DFBPPR2034 ---- Plant proteins ---- Kinesin-like protein KIN-8B Source.27: DFBPPR2087 ---- Plant proteins ---- Cytokinin dehydrogenase 10 Source.28: DFBPPR2093 ---- Plant proteins ---- Ent-kaurene oxidase-like 5 Source.29: DFBPPR2133 ---- Plant proteins ---- Probable diaminopimelate decarboxylase, chloroplastic Source.30: DFBPPR2162 ---- Plant proteins ---- Very-long-chain aldehyde decarbonylase GL1-7 Source.31: DFBPPR2172 ---- Plant proteins ---- S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase Source.32: DFBPPR2203 ---- Plant proteins ---- Protein SHORT-ROOT 2 Source.33: DFBPPR2247 ---- Plant proteins ---- Phytochrome C Source.34: DFBPPR2259 ---- Plant proteins ---- Inorganic phosphate transporter 1-1 Source.35: DFBPPR2263 ---- Plant proteins ---- CBL-interacting protein kinase 29 Source.36: DFBPPR2476 ---- Plant proteins ---- Fumarylacetoacetase Source.37: DFBPPR2477 ---- Plant proteins ---- Inorganic phosphate transporter 1-2 Source.38: DFBPPR2535 ---- Plant proteins ---- Probable glucuronosyltransferase Os04g0650300 Source.39: DFBPPR2551 ---- Plant proteins ---- Pyruvate decarboxylase 2 Source.40: DFBPPR2558 ---- Plant proteins ---- Pyruvate decarboxylase 1 Source.41: DFBPPR2564 ---- Plant proteins ---- Pyruvate decarboxylase 3 Source.42: DFBPPR2593 ---- Plant proteins ---- Probable lipoxygenase 8, chloroplastic Source.43: DFBPPR2688 ---- Plant proteins ---- Regulatory-associated protein of TOR 2 Source.44: DFBPPR2722 ---- Plant proteins ---- DEAD-box ATP-dependent RNA helicase 20 Source.45: DFBPPR2751 ---- Plant proteins ---- Actin-7 Source.46: DFBPPR2763 ---- Plant proteins ---- Actin-1 Source.47: DFBPPR2981 ---- Plant proteins ---- Beta-glucosidase 19 Source.48: DFBPPR2989 ---- Plant proteins ---- Actin-2 Source.49: DFBPPR3055 ---- Plant proteins ---- Chitin-inducible gibberellin-responsive protein 1 Source.50: DFBPPR3087 ---- Plant proteins ---- Actin-3 Source.51: DFBPPR3130 ---- Plant proteins ---- COP9 signalosome complex subunit 6 Source.52: DFBPPR3184 ---- Plant proteins ---- Stromal processing peptidase, chloroplastic Source.53: DFBPPR3391 ---- Plant proteins ---- Homeobox-leucine zipper protein HOX28 Source.54: DFBPPR3427 ---- Plant proteins ---- Putrescine hydroxycinnamoyltransferase 1 Source.55: DFBPPR3438 ---- Plant proteins ---- Protein ROLLING AND ERECT LEAF 2 Source.56: DFBPPR3450 ---- Plant proteins ---- Disease resistance protein RGA5 Source.57: DFBPPR3628 ---- Plant proteins ---- Kinesin-like protein KIN-13B Source.58: DFBPPR3693 ---- Plant proteins ---- Probable potassium transporter 9 Source.59: DFBPPR3696 ---- Plant proteins ---- Zinc-finger homeodomain protein 6 Source.60: DFBPPR3863 ---- Plant proteins ---- Cyclin-B1-1 Source.61: DFBPPR3897 ---- Plant proteins ---- Putative inorganic phosphate transporter 1-13 Source.62: DFBPPR3904 ---- Plant proteins ---- Cyclin-B1-5 Source.63: DFBPPR3929 ---- Plant proteins ---- IAA-amino acid hydrolase ILR1-like 1 Source.64: DFBPPR4005 ---- Plant proteins ---- Casparian strip membrane protein 2 Source.65: DFBPPR4022 ---- Plant proteins ---- Protein TIFY 11f Source.66: DFBPPR4053 ---- Plant proteins ---- Protein argonaute 1B Source.67: DFBPPR4121 ---- Plant proteins ---- Protein argonaute 1C Source.68: DFBPPR4301 ---- Plant proteins ---- Protein argonaute 16 Source.69: DFBPPR4399 ---- Plant proteins ---- IAA-amino acid hydrolase ILR1-like 5 Source.70: DFBPPR4426 ---- Plant proteins ---- Protein argonaute 18 Source.71: DFBPPR4460 ---- Plant proteins ---- Protein argonaute 3 Source.72: DFBPPR4469 ---- Plant proteins ---- Protein argonaute 11 Source.73: DFBPPR4475 ---- Plant proteins ---- Protein argonaute 14 Source.74: DFBPPR4484 ---- Plant proteins ---- Protein argonaute 12 Source.75: DFBPPR4534 ---- Plant proteins ---- Protein argonaute 4A Source.76: DFBPPR4538 ---- Plant proteins ---- Protein argonaute 2 Source.77: DFBPPR4540 ---- Plant proteins ---- Protein argonaute 1A Source.78: DFBPPR4578 ---- Plant proteins ---- Protein argonaute 1D Source.79: DFBPPR4587 ---- Plant proteins ---- Protein argonaute 13 Source.80: DFBPPR4602 ---- Plant proteins ---- Protein argonaute 15 Source.81: DFBPPR4617 ---- Plant proteins ---- Probable cleavage and polyadenylation specificity factor subunit 1 Source.82: DFBPPR4661 ---- Plant proteins ---- Protein argonaute 4B Source.83: DFBPPR4684 ---- Plant proteins ---- BURP domain-containing protein 17 Source.84: DFBPPR4756 ---- Plant proteins ---- Zinc finger CCCH domain-containing protein 18 Source.85: DFBPPR4944 ---- Plant proteins ---- B3 domain-containing protein LFL1 Source.86: DFBPPR4971 ---- Plant proteins ---- Purple acid phosphatase Source.87: DFBPPR4978 ---- Plant proteins ---- 2-hydroxyisoflavanone dehydratase Source.88: DFBPPR4998 ---- Plant proteins ---- Alternative oxidase 3, mitochondrial Source.89: DFBPPR5044 ---- Plant proteins ---- Cytochrome c oxidase subunit 3 Source.90: DFBPPR5074 ---- Plant proteins ---- Phytochrome B Source.91: DFBPPR5140 ---- Plant proteins ---- Basic 7S globulin 2 Source.92: DFBPPR5185 ---- Plant proteins ---- Actin-1 Source.93: DFBPPR5245 ---- Plant proteins ---- Omega-6 fatty acid desaturase, chloroplastic Source.94: DFBPPR5283 ---- Plant proteins ---- Actin-3 Source.95: DFBPPR5296 ---- Plant proteins ---- 18 kDa seed maturation protein Source.96: DFBPPR5440 ---- Plant proteins ---- Adenylyltransferase and sulfurtransferase MOCS3-1 Source.97: DFBPPR5459 ---- Plant proteins ---- Adenylyltransferase and sulfurtransferase MOCS3-2 Source.98: DFBPPR5733 ---- Plant proteins ---- Pyruvate decarboxylase 1 Source.99: DFBPPR5841 ---- Plant proteins ---- Actin-1 Source.100: DFBPPR5854 ---- Plant proteins ---- Retinoblastoma-related protein 3 Source.101: DFBPPR5880 ---- Plant proteins ---- Protein LIGULELESS 1 Source.102: DFBPPR5958 ---- Plant proteins ---- Cytochrome c oxidase subunit 3 Source.103: DFBPPR6240 ---- Plant proteins ---- Stromal processing peptidase, chloroplastic Source.104: DFBPPR6407 ---- Plant proteins ---- Pyruvate decarboxylase 1 Source.105: DFBPPR6428 ---- Plant proteins ---- Imidazoleglycerol-phosphate dehydratase, chloroplastic Source.106: DFBPPR6550 ---- Plant proteins ---- Actin-3 Source.107: DFBPPR6551 ---- Plant proteins ---- Actin-2 Source.108: DFBPPR6552 ---- Plant proteins ---- Actin-1 Source.109: DFBPPR6778 ---- Plant proteins ---- Cytochrome c oxidase subunit 3 Source.110: DFBPPR7007 ---- Plant proteins ---- Protein Barley B recombinant Source.111: DFBPPR7083 ---- Plant proteins ---- Lipoxygenase 2.2, chloroplastic Source.112: DFBPPR7503 ---- Plant proteins ---- Omega-6 fatty acid desaturase, chloroplastic Source.113: DFBPPR8194 ---- Plant proteins ---- 1-aminocyclopropane-1-carboxylate synthase CMA101 Source.114: DFBPPR15985 ---- Animal proteins ---- von Willebrand factor Source.115: DFBPPR16019 ---- Animal proteins ---- Multidrug resistance-associated protein 1 Source.116: DFBPPR16188 ---- Animal proteins ---- Actin, cytoplasmic 1 Source.117: DFBPPR16263 ---- Animal proteins ---- Protein 4.1 Source.118: DFBPPR16317 ---- Animal proteins ---- Sulfotransferase family cytosolic 1B member 1 Source.119: DFBPPR16318 ---- Animal proteins ---- Sulfotransferase family cytosolic 1B member 1 Source.120: DFBPPR16627 ---- Animal proteins ---- 60S ribosomal protein L15 Source.121: DFBPPR16847 ---- Animal proteins ---- Fibrinogen alpha chain Source.122: DFBPPR16875 ---- Animal proteins ---- von Willebrand factor Source.123: DFBPPR16997 ---- Animal proteins ---- Electrogenic sodium bicarbonate cotransporter 1 Source.124: DFBPPR17127 ---- Animal proteins ---- Multidrug resistance-associated protein 1 Source.125: DFBPPR17154 ---- Animal proteins ---- Actin, cytoplasmic 2 Source.126: DFBPPR17155 ---- Animal proteins ---- Actin, cytoplasmic 2 Source.127: DFBPPR17347 ---- Animal proteins ---- Phytanoyl-CoA dioxygenase, peroxisomal Source.128: DFBPPR17396 ---- Animal proteins ---- Trans-acting T-cell-specific transcription factor GATA-3 Source.129: DFBPPR17450 ---- Animal proteins ---- Adhesion G protein-coupled receptor L3 Source.130: DFBPPR17514 ---- Animal proteins ---- Actin, alpha skeletal muscle Source.131: DFBPPR17576 ---- Animal proteins ---- Fibrillin-1 Source.132: DFBPPR17595 ---- Animal proteins ---- Cytochrome c oxidase subunit 3 Source.133: DFBPPR17744 ---- Animal proteins ---- Protein argonaute-2 Source.134: DFBPPR17747 ---- Animal proteins ---- Actin, cytoplasmic 1 Source.135: DFBPPR17991 ---- Animal proteins ---- Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' Source.136: DFBPPR18042 ---- Animal proteins ---- Acyl-CoA desaturase Source.137: DFBPPR18053 ---- Animal proteins ---- Amiloride-sensitive sodium channel subunit beta Source.138: DFBPPR18076 ---- Animal proteins ---- 26S proteasome regulatory subunit 8 Source.139: DFBPPR18129 ---- Animal proteins ---- Ubiquitin carboxyl-terminal hydrolase 15 Source.140: DFBPPR18151 ---- Animal proteins ---- Coagulation factor XIII A chain Source.141: DFBPPR18240 ---- Animal proteins ---- Dual specificity protein kinase CLK3 Source.142: DFBPPR18360 ---- Animal proteins ---- Desmocollin-3 Source.143: DFBPPR18392 ---- Animal proteins ---- Centrosomal protein of 290 kDa Source.144: DFBPPR18406 ---- Animal proteins ---- Angiotensinogen Source.145: DFBPPR18440 ---- Animal proteins ---- Protein 4.2 Source.146: DFBPPR18467 ---- Animal proteins ---- Alpha-aminoadipic semialdehyde synthase, mitochondrial Source.147: DFBPPR18543 ---- Animal proteins ---- Proproteinase E Source.148: DFBPPR18554 ---- Animal proteins ---- Arylsulfatase A Source.149: DFBPPR18574 ---- Animal proteins ---- Stearoyl-CoA desaturase 5 Source.150: DFBPPR18701 ---- Animal proteins ---- Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase Source.151: DFBPPR18817 ---- Animal proteins ---- Protein argonaute-3 Source.152: DFBPPR18929 ---- Animal proteins ---- Dipeptidyl peptidase 1 Source.153: DFBPPR18941 ---- Animal proteins ---- 5-aminolevulinate synthase, nonspecific, mitochondrial Source.154: DFBPPR18979 ---- Animal proteins ---- Alpha-2-macroglobulin Source.155: DFBPPR19073 ---- Animal proteins ---- Ubiquitin carboxyl-terminal hydrolase 21 Source.156: DFBPPR19138 ---- Animal proteins ---- Protein-glutamine gamma-glutamyltransferase E Source.157: DFBPPR19147 ---- Animal proteins ---- X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 Source.158: DFBPPR19353 ---- Animal proteins ---- Protein-glutamine gamma-glutamyltransferase 2 Source.159: DFBPPR19448 ---- Animal proteins ---- Trimethyllysine dioxygenase, mitochondrial Source.160: DFBPPR19612 ---- Animal proteins ---- Lysosomal-trafficking regulator Source.161: DFBPPR19936 ---- Animal proteins ---- Myelin-associated neurite-outgrowth inhibitor Source.162: DFBPPR20080 ---- Animal proteins ---- 26S proteasome regulatory subunit 6B Source.163: DFBPPR20129 ---- Animal proteins ---- 2-aminomuconic semialdehyde dehydrogenase Source.164: DFBPPR20146 ---- Animal proteins ---- Syntaxin-binding protein 6 Source.165: DFBPPR20210 ---- Animal proteins ---- Exonuclease V Source.166: DFBPPR20412 ---- Animal proteins ---- Protein disulfide-isomerase A4 Source.167: DFBPPR20430 ---- Animal proteins ---- Zinc finger protein 69 homolog Source.168: DFBPPR20567 ---- Animal proteins ---- Prokineticin-2 Source.169: DFBPPR20833 ---- Animal proteins ---- Src kinase-associated phosphoprotein 2 Source.170: DFBPPR20917 ---- Animal proteins ---- RNA binding protein fox-1 homolog 3 Source.171: DFBPPR20968 ---- Animal proteins ---- Ras GTPase-activating protein 3 Source.172: DFBPPR21037 ---- Animal proteins ---- Zinc finger protein 574 Source.173: DFBPPR21047 ---- Animal proteins ---- WD repeat-containing protein 48 Source.174: DFBPPR21126 ---- Animal proteins ---- Methionine--tRNA ligase, mitochondrial Source.175: DFBPPR21129 ---- Animal proteins ---- 60S ribosomal protein L15 Source.176: DFBPPR21162 ---- Animal proteins ---- Neurogenic differentiation factor 6 Source.177: DFBPPR21402 ---- Animal proteins ---- Pyridoxal phosphate phosphatase PHOSPHO2 Source.178: DFBPPR21459 ---- Animal proteins ---- RELT-like protein 2 Source.179: DFBPPR21535 ---- Animal proteins ---- Gastrotropin Source.180: DFBPPR21552 ---- Animal proteins ---- SPRY domain-containing SOCS box protein 3 Source.181: DFBPPR21715 ---- Animal proteins ---- Junctional protein associated with coronary artery disease homolog Source.182: DFBPPR21835 ---- Animal proteins ---- Protein misato homolog 1 Source.183: DFBPPR21952 ---- Animal proteins ---- Conserved oligomeric Golgi complex subunit 6 Source.184: DFBPPR21999 ---- Animal proteins ---- Rho GDP-dissociation inhibitor 3 Source.185: DFBPPR22031 ---- Animal proteins ---- KxDL motif-containing protein 1 Source.186: DFBPPR22139 ---- Animal proteins ---- WD repeat and SOCS box-containing protein 2 Source.187: DFBPPR22188 ---- Animal proteins ---- ER membrane protein complex subunit 8 Source.188: DFBPPR22222 ---- Animal proteins ---- PGC-1 and ERR-induced regulator in muscle protein 1 Source.189: DFBPPR22257 ---- Animal proteins ---- TLC domain-containing protein 5 Source.190: DFBPPR22325 ---- Animal proteins ---- Armadillo repeat-containing protein 2 Source.191: DFBPPR22435 ---- Animal proteins ---- CDAN1-interacting nuclease 1 Source.192: DFBPPR22443 ---- Animal proteins ---- Stromal cell-derived factor 2 Source.193: DFBPPR22468 ---- Animal proteins ---- Queuosine salvage protein Source.194: DFBPPR22605 ---- Animal proteins ---- Transmembrane protein 254 Source.195: DFBPPR22616 ---- Animal proteins ---- Jhy protein homolog Source.196: DFBPPR8645 ---- Animal proteins ---- NT-3 growth factor receptor Source.197: DFBPPR8677 ---- Animal proteins ---- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Source.198: DFBPPR8710 ---- Animal proteins ---- Leptin receptor Source.199: DFBPPR8720 ---- Animal proteins ---- Interleukin-4 Source.200: DFBPPR8726 ---- Animal proteins ---- Serine-protein kinase ATM Source.201: DFBPPR8830 ---- Animal proteins ---- Electrogenic sodium bicarbonate cotransporter 1 Source.202: DFBPPR8884 ---- Animal proteins ---- Actin, cytoplasmic 1 Source.203: DFBPPR8971 ---- Animal proteins ---- Fibrillin-1 Source.204: DFBPPR9042 ---- Animal proteins ---- 4-hydroxyphenylpyruvate dioxygenase Source.205: DFBPPR9098 ---- Animal proteins ---- Gastrotropin Source.206: DFBPPR9167 ---- Animal proteins ---- Melanocyte-stimulating hormone receptor Source.207: DFBPPR9269 ---- Animal proteins ---- Cytochrome c oxidase subunit 3 Source.208: DFBPPR9374 ---- Animal proteins ---- Casein kinase II subunit beta Source.209: DFBPPR9408 ---- Animal proteins ---- CD70 antigen Source.210: DFBPPR9410 ---- Animal proteins ---- Acyl-CoA desaturase Source.211: DFBPPR9411 ---- Animal proteins ---- Acyl-CoA desaturase Source.212: DFBPPR9412 ---- Animal proteins ---- Acyl-CoA desaturase Source.213: DFBPPR9760 ---- Animal proteins ---- Tripartite motif-containing protein 10 Source.214: DFBPPR9914 ---- Animal proteins ---- 60S ribosomal protein L15 Source.215: DFBPPR9957 ---- Animal proteins ---- Ovoinhibitor Source.216: DFBPPR10103 ---- Animal proteins ---- Actin, cytoplasmic 1 Source.217: DFBPPR10270 ---- Animal proteins ---- Agrin Source.218: DFBPPR10279 ---- Animal proteins ---- Platelet-derived growth factor C Source.219: DFBPPR10282 ---- Animal proteins ---- Reversion-inducing cysteine-rich protein with Kazal motifs Source.220: DFBPPR10310 ---- Animal proteins ---- Xanthine dehydrogenase/oxidase Source.221: DFBPPR10319 ---- Animal proteins ---- Actin, alpha cardiac muscle 1 Source.222: DFBPPR10338 ---- Animal proteins ---- Actin, alpha skeletal muscle Source.223: DFBPPR10410 ---- Animal proteins ---- Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' Source.224: DFBPPR10444 ---- Animal proteins ---- 5-aminolevulinate synthase, nonspecific, mitochondrial Source.225: DFBPPR10503 ---- Animal proteins ---- Follicle-stimulating hormone receptor Source.226: DFBPPR10530 ---- Animal proteins ---- Osteopontin Source.227: DFBPPR10554 ---- Animal proteins ---- Creatine kinase S-type, mitochondrial Source.228: DFBPPR10558 ---- Animal proteins ---- Lysosome-associated membrane glycoprotein 2 Source.229: DFBPPR10767 ---- Animal proteins ---- Sodium/potassium-transporting ATPase subunit alpha-1 Source.230: DFBPPR10777 ---- Animal proteins ---- Actin, cytoplasmic type 5 Source.231: DFBPPR10810 ---- Animal proteins ---- Actin, cytoplasmic 2 Source.232: DFBPPR10887 ---- Animal proteins ---- Cytochrome c oxidase subunit 3 Source.233: DFBPPR10930 ---- Animal proteins ---- WD repeat-containing protein 48 Source.234: DFBPPR10940 ---- Animal proteins ---- Protein piccolo Source.235: DFBPPR10948 ---- Animal proteins ---- Kinesin-like protein KIF2A Source.236: DFBPPR11021 ---- Animal proteins ---- Protein Jumonji Source.237: DFBPPR11038 ---- Animal proteins ---- Cytosolic endo-beta-N-acetylglucosaminidase Source.238: DFBPPR11129 ---- Animal proteins ---- Zinc finger protein ZIC 1 Source.239: DFBPPR11158 ---- Animal proteins ---- Phosphatase and actin regulator 1 Source.240: DFBPPR11168 ---- Animal proteins ---- Trimethyllysine dioxygenase, mitochondrial Source.241: DFBPPR11191 ---- Animal proteins ---- Protein argonaute-3 Source.242: DFBPPR11299 ---- Animal proteins ---- Casein kinase II subunit beta Source.243: DFBPPR11307 ---- Animal proteins ---- Thyrotropin subunit beta Source.244: DFBPPR11482 ---- Animal proteins ---- Histone deacetylase 9 Source.245: DFBPPR11530 ---- Animal proteins ---- Probable cation-transporting ATPase 13A4 Source.246: DFBPPR11615 ---- Animal proteins ---- Sulfotransferase family cytosolic 1B member 1 Source.247: DFBPPR11643 ---- Animal proteins ---- GDNF family receptor alpha-4 Source.248: DFBPPR11793 ---- Animal proteins ---- Fas-binding factor 1 homolog Source.249: DFBPPR11872 ---- Animal proteins ---- Protein argonaute-4 Source.250: DFBPPR12109 ---- Animal proteins ---- Integrator complex subunit 10 Source.251: DFBPPR12153 ---- Animal proteins ---- Zinc finger CCCH domain-containing protein 11A Source.252: DFBPPR12196 ---- Animal proteins ---- 60S ribosomal protein L15 Source.253: DFBPPR12206 ---- Animal proteins ---- CDAN1-interacting nuclease 1 Source.254: DFBPPR12268 ---- Animal proteins ---- Actin, alpha skeletal muscle Source.255: DFBPPR12279 ---- Animal proteins ---- Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform Source.256: DFBPPR12295 ---- Animal proteins ---- Sodium/hydrogen exchanger 3 Source.257: DFBPPR12323 ---- Animal proteins ---- Flavin-containing monooxygenase 5 Source.258: DFBPPR12335 ---- Animal proteins ---- Bone morphogenetic protein 4 Source.259: DFBPPR12440 ---- Animal proteins ---- Protein argonaute-2 Source.260: DFBPPR12458 ---- Animal proteins ---- Electrogenic sodium bicarbonate cotransporter 1 Source.261: DFBPPR12510 ---- Animal proteins ---- Phospholemman Source.262: DFBPPR12565 ---- Animal proteins ---- Protein-glutamine gamma-glutamyltransferase K Source.263: DFBPPR12668 ---- Animal proteins ---- Anion exchange protein 3 Source.264: DFBPPR12700 ---- Animal proteins ---- Actin, cytoplasmic 1 Source.265: DFBPPR12701 ---- Animal proteins ---- Actin, cytoplasmic 1 Source.266: DFBPPR12831 ---- Animal proteins ---- Serine--pyruvate aminotransferase Source.267: DFBPPR12838 ---- Animal proteins ---- Cytochrome c oxidase subunit 3 Source.268: DFBPPR12863 ---- Animal proteins ---- Casein kinase II subunit beta Source.269: DFBPPR13145 ---- Animal proteins ---- Sodium/potassium-transporting ATPase subunit alpha-1 Source.270: DFBPPR13231 ---- Animal proteins ---- Actin, cytoplasmic 1 Source.271: DFBPPR13304 ---- Animal proteins ---- Cytochrome c oxidase subunit 3 Source.272: DFBPPR13440 ---- Animal proteins ---- CSC1-like protein 1 Source.273: DFBPPR13467 ---- Animal proteins ---- Acyl-CoA desaturase Source.274: DFBPPR13621 ---- Animal proteins ---- Amiloride-sensitive sodium channel subunit beta Source.275: DFBPPR13675 ---- Animal proteins ---- Cytochrome c oxidase subunit 3 Source.276: DFBPPR13690 ---- Animal proteins ---- Angiotensinogen Source.277: DFBPPR13731 ---- Animal proteins ---- Acyl-CoA desaturase Source.278: DFBPPR13769 ---- Animal proteins ---- Actin, cytoplasmic 1 Source.279: DFBPPR13996 ---- Animal proteins ---- Actin, alpha skeletal muscle Source.280: DFBPPR14006 ---- Animal proteins ---- Acyl-CoA desaturase Source.281: DFBPPR14015 ---- Animal proteins ---- Cytochrome c oxidase subunit 3 Source.282: DFBPPR14021 ---- Animal proteins ---- Actin, cytoplasmic 1 Source.283: DFBPPR14119 ---- Marine protein ---- Cytochrome c oxidase subunit 3 Source.284: DFBPPR14143 ---- Marine protein ---- Actin, cytoplasmic 1 Source.285: DFBPPR14191 ---- Marine protein ---- THAP domain-containing protein 1 Source.286: DFBPPR14554 ---- Marine protein ---- Shaker-related potassium channel tsha2 Source.287: DFBPPR14627 ---- Marine protein ---- Cytochrome c oxidase subunit 3 Source.288: DFBPPR14814 ---- Marine protein ---- Superoxide dismutase [Mn], mitochondrial Source.289: DFBPPR14859 ---- Marine protein ---- Sodium/potassium-transporting ATPase subunit alpha-1 Source.290: DFBPPR14935 ---- Microorganism protein ---- Actin Source.291: DFBPPR14937 ---- Microorganism protein ---- Sulfate adenylyltransferase Source.292: DFBPPR14948 ---- Microorganism protein ---- Ubiquitin carboxyl-terminal hydrolase 4 Source.293: DFBPPR15015 ---- Microorganism protein ---- Postreplication repair E3 ubiquitin-protein ligase RAD18 Source.294: DFBPPR15022 ---- Microorganism protein ---- Pyruvate decarboxylase Source.295: DFBPPR15065 ---- Microorganism protein ---- Lactose regulatory protein LAC9 Source.296: DFBPPR15070 ---- Microorganism protein ---- Transcription factor MBP1 Source.297: DFBPPR15134 ---- Microorganism protein ---- Eukaryotic translation initiation factor 3 subunit A Source.298: DFBPPR15188 ---- Microorganism protein ---- DNA mismatch repair protein MSH3 Source.299: DFBPPR15238 ---- Microorganism protein ---- Pre-mRNA-splicing factor CLF1 Source.300: DFBPPR15401 ---- Microorganism protein ---- Probable cyclodipeptide synthase PUL1 Source.301: DFBPPR15482 ---- Microorganism protein ---- Altered inheritance of mitochondria protein 44 Source.302: DFBPPR15670 ---- Microorganism protein ---- Imidazoleglycerol-phosphate dehydratase Source.303: DFBPPR15761 ---- Microorganism protein ---- Eisosome protein 1 Source.304: DFBPPR15826 ---- Microorganism protein ---- Galactose-1-phosphate uridylyltransferase Source.305: DFBPPR15848 ---- Microorganism protein ---- Polyphenol oxidase 2 Source.306: DFBPPR7785 ---- Plant protein ---- Alanine--tRNA ligase, chloroplastic/mitochondrial Source.307: DFBPPR7802 ---- Plant protein ---- Phytochrome B Source.308: DFBPPR7811 ---- Plant protein ---- Fatty acid desaturase DES2 Source.309: DFBPPR7825 ---- Plant protein ---- Phytochrome C Source.310: DFBPPR7844 ---- Plant protein ---- Actin-1 Source.311: DFBPPR7952 ---- Plant protein ---- Cytochrome c oxidase subunit 3 Source.312: DFBPPR8027 ---- Plant protein ---- Fe(3+)-Zn(2+) purple acid phosphatase Source.313: DFBPPR8029 ---- Plant protein ---- Vignain Source.314: DFBPPR8274 ---- Plant protein ---- Cytochrome c oxidase subunit 3
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

ACE-inhibitory activity	The peptide exhibited low Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) inhibitory activity with an IC₅₀ value of 800 uM (310 μg/mL).
Specific target protein(s)	Specific Target Protein(s): Angiotensin-converting enzyme

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Non-bitter taste ^prediction

SMILES

N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)O

Preparation method

Mode of preparation	Synthesis
Enzyme(s)/starter culture	Peptides were synthesized by a solid phase method with a peptide synthesizer (Biosearch SAM TWO).

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Yokoyama K, Chiba H, Yoshikawa M. Peptide inhibitors for angiotensin I-converting enzyme from thermolysin digest of dried bonito. Biosci Biotechnol Biochem. 1992 Oct;56(10):1541-5. PMID: 1369054 DOI: 10.1271/bbb.56.1541
Other literature(s)	N.D
PubDate	1992