Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPACEI1789(ACE-inhibitory peptide)

DFBP ID	DFBPACEI1789
Peptide sequence	LALR
Type	Native peptide
Peptide/Function name	ACE-inhibitory peptide

Function-activity relationship

Main bioactivity	ACE-inhibitory activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

Leu-Ala-Leu-Arg

Single-letter amino acid

LALR

Peptide length

Peptide mass

Experimental mass	Theoretical mass
N.D	471.58 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

11.04 ^c

IC₅₀

1268 μM

pIC₅₀

-3.103

GRAVY

1.2250^c

Hydrophilic residue ratio

75%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Marine bivalve
Organism/Source	Mactra veneriformis (Mactra veneriformis)
Precursor protein	M. veneriformis hydrolysates
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR0850 ---- Plant proteins ---- Calcium-dependent protein kinase 7 Source.2: DFBPPR0923 ---- Plant proteins ---- Lysine-specific demethylase JMJ703 Source.3: DFBPPR0927 ---- Plant proteins ---- Serine/threonine-protein kinase TOR Source.4: DFBPPR0971 ---- Plant proteins ---- Protein STAR1 Source.5: DFBPPR0993 ---- Plant proteins ---- E3 ubiquitin-protein ligase BRE1-like 2 Source.6: DFBPPR1003 ---- Plant proteins ---- Soluble starch synthase 1, chloroplastic/amyloplastic Source.7: DFBPPR1005 ---- Plant proteins ---- Cellulose synthase A catalytic subunit 7 [UDP-forming] Source.8: DFBPPR1013 ---- Plant proteins ---- DNA (cytosine-5)-methyltransferase 1B Source.9: DFBPPR1074 ---- Plant proteins ---- Protein DWARF AND LOW-TILLERING Source.10: DFBPPR1100 ---- Plant proteins ---- Soluble starch synthase 2-3, chloroplastic/amyloplastic Source.11: DFBPPR1143 ---- Plant proteins ---- Mitogen-activated protein kinase 13 Source.12: DFBPPR1163 ---- Plant proteins ---- Cation-chloride cotransporter 1 Source.13: DFBPPR1221 ---- Plant proteins ---- Probable GTP diphosphokinase CRSH1, chloroplastic Source.14: DFBPPR1277 ---- Plant proteins ---- Probable cellulose synthase A catalytic subunit 8 [UDP-forming] Source.15: DFBPPR1344 ---- Plant proteins ---- Probable glutamate carboxypeptidase PLA3 Source.16: DFBPPR1369 ---- Plant proteins ---- Probable cellulose synthase A catalytic subunit 1 [UDP-forming] Source.17: DFBPPR1385 ---- Plant proteins ---- Glutamine synthetase cytosolic isozyme 1-2 Source.18: DFBPPR1452 ---- Plant proteins ---- Probable cellulose synthase A catalytic subunit 2 [UDP-forming] Source.19: DFBPPR1467 ---- Plant proteins ---- Chaperone protein ClpD1, chloroplastic Source.20: DFBPPR1520 ---- Plant proteins ---- Very-long-chain aldehyde decarbonylase GL1-3 Source.21: DFBPPR1568 ---- Plant proteins ---- Phosphate transporter PHO1-2 Source.22: DFBPPR1616 ---- Plant proteins ---- Anthranilate synthase alpha subunit 2, chloroplastic Source.23: DFBPPR1666 ---- Plant proteins ---- Cysteine--tRNA ligase CPS1 homolog, chloroplastic/mitochondrial Source.24: DFBPPR1680 ---- Plant proteins ---- Dihydroorotate dehydrogenase (quinone), mitochondrial Source.25: DFBPPR1714 ---- Plant proteins ---- Protein MAO HUZI 4, chloroplastic Source.26: DFBPPR1894 ---- Plant proteins ---- Clathrin heavy chain 1 Source.27: DFBPPR1898 ---- Plant proteins ---- Clathrin heavy chain 2 Source.28: DFBPPR1908 ---- Plant proteins ---- Proteasome subunit alpha type-1 Source.29: DFBPPR1917 ---- Plant proteins ---- Kinesin-like protein KIN-12A Source.30: DFBPPR1968 ---- Plant proteins ---- Kinesin-like protein KIN-14I Source.31: DFBPPR1976 ---- Plant proteins ---- Mitogen-activated protein kinase 15 Source.32: DFBPPR1981 ---- Plant proteins ---- Signal peptide peptidase 2 Source.33: DFBPPR2026 ---- Plant proteins ---- Proteasome subunit alpha type-5 Source.34: DFBPPR2039 ---- Plant proteins ---- Protein MONOCULM 1 Source.35: DFBPPR2133 ---- Plant proteins ---- Probable diaminopimelate decarboxylase, chloroplastic Source.36: DFBPPR2195 ---- Plant proteins ---- Signal peptide peptidase 1 Source.37: DFBPPR2253 ---- Plant proteins ---- Probable methylenetetrahydrofolate reductase Source.38: DFBPPR2273 ---- Plant proteins ---- Probable glucomannan 4-beta-mannosyltransferase 6 Source.39: DFBPPR2284 ---- Plant proteins ---- Probable glucan 1,3-alpha-glucosidase Source.40: DFBPPR2300 ---- Plant proteins ---- Cellulose synthase-like protein H2 Source.41: DFBPPR2324 ---- Plant proteins ---- Ubiquitin-NEDD8-like protein RUB1 Source.42: DFBPPR2338 ---- Plant proteins ---- Ubiquitin-NEDD8-like protein RUB2 Source.43: DFBPPR2356 ---- Plant proteins ---- Ubiquitin-like protein-NEDD8-like protein RUB3 Source.44: DFBPPR2361 ---- Plant proteins ---- Iron-phytosiderophore transporter YSL15 Source.45: DFBPPR2362 ---- Plant proteins ---- Metal-nicotianamine transporter YSL2 Source.46: DFBPPR2588 ---- Plant proteins ---- Putative heat stress transcription factor B-4a Source.47: DFBPPR2658 ---- Plant proteins ---- Vacuolar cation/proton exchanger 1b Source.48: DFBPPR2687 ---- Plant proteins ---- Protein AMEIOTIC 1 homolog Source.49: DFBPPR2704 ---- Plant proteins ---- DEAD-box ATP-dependent RNA helicase 18 Source.50: DFBPPR2710 ---- Plant proteins ---- 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic Source.51: DFBPPR2718 ---- Plant proteins ---- Kinesin-like protein KIN-14M Source.52: DFBPPR2734 ---- Plant proteins ---- Cation-chloride cotransporter 2 Source.53: DFBPPR2761 ---- Plant proteins ---- Ent-kaurene synthase-like 3 Source.54: DFBPPR2783 ---- Plant proteins ---- tRNA (guanine-N(7)-)-methyltransferase Source.55: DFBPPR2808 ---- Plant proteins ---- Origin of replication complex subunit 1 Source.56: DFBPPR2810 ---- Plant proteins ---- Probable N6-adenosine-methyltransferase MT-A70-like Source.57: DFBPPR2878 ---- Plant proteins ---- 26S proteasome non-ATPase regulatory subunit 4 homolog Source.58: DFBPPR2991 ---- Plant proteins ---- 26S proteasome regulatory subunit 6A homolog Source.59: DFBPPR3098 ---- Plant proteins ---- GTPase ERA-like, chloroplastic Source.60: DFBPPR3160 ---- Plant proteins ---- Endoglucanase 11 Source.61: DFBPPR3214 ---- Plant proteins ---- Probable adenylate kinase 5, chloroplastic Source.62: DFBPPR3330 ---- Plant proteins ---- Putative 12-oxophytodienoate reductase 10 Source.63: DFBPPR3350 ---- Plant proteins ---- DEAD-box ATP-dependent RNA helicase 22 Source.64: DFBPPR3374 ---- Plant proteins ---- Auxin-responsive protein IAA19 Source.65: DFBPPR3406 ---- Plant proteins ---- Probable metal-nicotianamine transporter YSL16 Source.66: DFBPPR3465 ---- Plant proteins ---- Deoxyhypusine hydroxylase-A Source.67: DFBPPR3545 ---- Plant proteins ---- Auxin response factor 3 Source.68: DFBPPR3815 ---- Plant proteins ---- Dehydration-responsive element-binding protein 1B Source.69: DFBPPR3818 ---- Plant proteins ---- 26S proteasome regulatory subunit 4 homolog Source.70: DFBPPR3857 ---- Plant proteins ---- DEAD-box ATP-dependent RNA helicase 57 Source.71: DFBPPR3956 ---- Plant proteins ---- Aquaporin SIP1-1 Source.72: DFBPPR4049 ---- Plant proteins ---- Dehydration-responsive element-binding protein 1C Source.73: DFBPPR4092 ---- Plant proteins ---- Putative serpin-Z5 Source.74: DFBPPR4127 ---- Plant proteins ---- Mitochondrial outer membrane protein porin 5 Source.75: DFBPPR4230 ---- Plant proteins ---- Cyclin-D1-1 Source.76: DFBPPR4269 ---- Plant proteins ---- Serine decarboxylase 3 Source.77: DFBPPR4346 ---- Plant proteins ---- Dehydration-responsive element-binding protein 1G Source.78: DFBPPR4571 ---- Plant proteins ---- CASP-like protein 1D1 Source.79: DFBPPR4595 ---- Plant proteins ---- Tubby-like F-box protein 9 Source.80: DFBPPR4615 ---- Plant proteins ---- CASP-like protein 1U3 Source.81: DFBPPR4639 ---- Plant proteins ---- CASP-like protein 4D1 Source.82: DFBPPR4750 ---- Plant proteins ---- Zinc finger CCCH domain-containing protein 9 Source.83: DFBPPR4822 ---- Plant proteins ---- Protein TAB2 homolog, chloroplastic Source.84: DFBPPR4886 ---- Plant proteins ---- DELLA protein SLR1 Source.85: DFBPPR4894 ---- Plant proteins ---- Mitogen-activated protein kinase 12 Source.86: DFBPPR4916 ---- Plant proteins ---- Anthranilate synthase alpha subunit 1, chloroplastic Source.87: DFBPPR4934 ---- Plant proteins ---- U-box domain-containing protein 70 Source.88: DFBPPR4951 ---- Plant proteins ---- Dehydration-responsive element-binding protein 1I Source.89: DFBPPR5081 ---- Plant proteins ---- Proteasome subunit alpha type-5 Source.90: DFBPPR5267 ---- Plant proteins ---- Casparian strip membrane protein 3 Source.91: DFBPPR5276 ---- Plant proteins ---- ATP synthase epsilon chain, chloroplastic Source.92: DFBPPR5396 ---- Plant proteins ---- DELLA protein DWARF8 Source.93: DFBPPR5436 ---- Plant proteins ---- Probable glutamate carboxypeptidase VP8 Source.94: DFBPPR5446 ---- Plant proteins ---- Protein OPAQUE1 Source.95: DFBPPR5462 ---- Plant proteins ---- Cysteine--tRNA ligase CPS1, chloroplastic/mitochondrial Source.96: DFBPPR5493 ---- Plant proteins ---- GTPase ERA1, chloroplastic Source.97: DFBPPR5547 ---- Plant proteins ---- Methylenetetrahydrofolate reductase 1 Source.98: DFBPPR5551 ---- Plant proteins ---- DNA repair protein RAD51 homolog A Source.99: DFBPPR5553 ---- Plant proteins ---- Pentatricopeptide repeat-containing protein ATP4, chloroplastic Source.100: DFBPPR5559 ---- Plant proteins ---- 15-cis-phytoene desaturase, chloroplastic/chromoplastic Source.101: DFBPPR5620 ---- Plant proteins ---- Zeta-carotene desaturase, chloroplastic/chromoplastic Source.102: DFBPPR5660 ---- Plant proteins ---- Iron-phytosiderophore transporter yellow stripe 1 Source.103: DFBPPR5759 ---- Plant proteins ---- Protein TAB2 homolog, chloroplastic Source.104: DFBPPR5812 ---- Plant proteins ---- tRNA (guanine-N(7)-)-methyltransferase Source.105: DFBPPR5874 ---- Plant proteins ---- Beta-fructofuranosidase, cell wall isozyme Source.106: DFBPPR5975 ---- Plant proteins ---- ATP synthase epsilon chain, chloroplastic Source.107: DFBPPR6047 ---- Plant proteins ---- CASP-like protein 1D1 Source.108: DFBPPR6048 ---- Plant proteins ---- CASP-like protein 5B1 Source.109: DFBPPR6050 ---- Plant proteins ---- CASP-like protein 4U1 Source.110: DFBPPR6272 ---- Plant proteins ---- Short-chain dehydrogenase TIC 32, chloroplastic Source.111: DFBPPR6336 ---- Plant proteins ---- Asparagine synthetase, root [glutamine-hydrolyzing] Source.112: DFBPPR6554 ---- Plant proteins ---- Retinoblastoma-related protein 1 Source.113: DFBPPR6555 ---- Plant proteins ---- Retinoblastoma-related protein 1 Source.114: DFBPPR6665 ---- Plant proteins ---- DELLA protein RHT-1 Source.115: DFBPPR6902 ---- Plant proteins ---- ATP synthase epsilon chain, chloroplastic Source.116: DFBPPR6937 ---- Plant proteins ---- Alpha/beta-gliadin A-IV Source.117: DFBPPR7088 ---- Plant proteins ---- DELLA protein SLN1 Source.118: DFBPPR7266 ---- Plant proteins ---- ATP synthase epsilon chain, chloroplastic Source.119: DFBPPR7621 ---- Milk proteins ---- Mucin-4 Source.120: DFBPPR8205 ---- Plant proteins ---- DELLA protein GAIP Source.121: DFBPPR8206 ---- Plant proteins ---- DELLA protein GAIP-B Source.122: DFBPPR8511 ---- Milk proteins ---- Transcobalamin-2 Source.123: DFBPPR15985 ---- Animal proteins ---- von Willebrand factor Source.124: DFBPPR15986 ---- Animal proteins ---- Toll-like receptor 2 Source.125: DFBPPR16022 ---- Animal proteins ---- Phospholipase A2 group XV Source.126: DFBPPR16031 ---- Animal proteins ---- DNA-dependent protein kinase catalytic subunit Source.127: DFBPPR16084 ---- Animal proteins ---- T-box transcription factor TBX2 Source.128: DFBPPR16145 ---- Animal proteins ---- Pleckstrin homology domain-containing family A member 8 Source.129: DFBPPR16164 ---- Animal proteins ---- Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 Source.130: DFBPPR16203 ---- Animal proteins ---- E3 ubiquitin-protein ligase RING1 Source.131: DFBPPR16207 ---- Animal proteins ---- Homeobox protein cut-like 1 Source.132: DFBPPR16220 ---- Animal proteins ---- Deoxyribonuclease-1 Source.133: DFBPPR16223 ---- Animal proteins ---- Actin-histidine N-methyltransferase Source.134: DFBPPR16314 ---- Animal proteins ---- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase Source.135: DFBPPR16501 ---- Animal proteins ---- F-box/LRR-repeat protein 15 Source.136: DFBPPR16545 ---- Animal proteins ---- Probable G-protein coupled receptor 83 Source.137: DFBPPR16590 ---- Animal proteins ---- Arylsulfatase K Source.138: DFBPPR16858 ---- Animal proteins ---- Thioredoxin-dependent peroxide reductase, mitochondrial Source.139: DFBPPR16865 ---- Animal proteins ---- Apolipoprotein E Source.140: DFBPPR16890 ---- Animal proteins ---- Peptidyl-prolyl cis-trans isomerase F, mitochondrial Source.141: DFBPPR16914 ---- Animal proteins ---- Phospholipase A2 group XV Source.142: DFBPPR16996 ---- Animal proteins ---- Retinol dehydrogenase 5 Source.143: DFBPPR17039 ---- Animal proteins ---- Nucleotide-binding oligomerization domain-containing protein 2 Source.144: DFBPPR17110 ---- Animal proteins ---- Diacylglycerol O-acyltransferase 2 Source.145: DFBPPR17313 ---- Animal proteins ---- Exostosin-1 Source.146: DFBPPR17327 ---- Animal proteins ---- Myotubularin Source.147: DFBPPR17331 ---- Animal proteins ---- Pyridoxal phosphate phosphatase Source.148: DFBPPR17338 ---- Animal proteins ---- Unconventional myosin-VI Source.149: DFBPPR17440 ---- Animal proteins ---- Clathrin heavy chain 1 Source.150: DFBPPR17493 ---- Animal proteins ---- Catechol O-methyltransferase Source.151: DFBPPR17558 ---- Animal proteins ---- Aldehyde dehydrogenase family 3 member B1 Source.152: DFBPPR17567 ---- Animal proteins ---- [F-actin]-monooxygenase MICAL1 Source.153: DFBPPR17759 ---- Animal proteins ---- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase Source.154: DFBPPR17951 ---- Animal proteins ---- Phospholipase DDHD1 Source.155: DFBPPR18005 ---- Animal proteins ---- Lutropin-choriogonadotropic hormone receptor Source.156: DFBPPR18251 ---- Animal proteins ---- Serum paraoxonase/arylesterase 2 Source.157: DFBPPR18328 ---- Animal proteins ---- Delta-aminolevulinic acid dehydratase Source.158: DFBPPR18490 ---- Animal proteins ---- N-terminal Xaa-Pro-Lys N-methyltransferase 1 Source.159: DFBPPR18744 ---- Animal proteins ---- Oxytocin receptor Source.160: DFBPPR18852 ---- Animal proteins ---- Pleckstrin homology domain-containing family A member 8 Source.161: DFBPPR18886 ---- Animal proteins ---- Interleukin-12 receptor subunit beta-2 Source.162: DFBPPR19028 ---- Animal proteins ---- DNA repair protein XRCC3 Source.163: DFBPPR19040 ---- Animal proteins ---- 26S proteasome non-ATPase regulatory subunit 11 Source.164: DFBPPR19058 ---- Animal proteins ---- Phosphatidylserine decarboxylase proenzyme, mitochondrial Source.165: DFBPPR19073 ---- Animal proteins ---- Ubiquitin carboxyl-terminal hydrolase 21 Source.166: DFBPPR19082 ---- Animal proteins ---- Protein SCO2 homolog, mitochondrial Source.167: DFBPPR19181 ---- Animal proteins ---- Solute carrier family 25 member 33 Source.168: DFBPPR19219 ---- Animal proteins ---- Cytochrome c oxidase subunit 7A2, mitochondrial Source.169: DFBPPR19254 ---- Animal proteins ---- Periaxin Source.170: DFBPPR19267 ---- Animal proteins ---- NEDD8 Source.171: DFBPPR19310 ---- Animal proteins ---- Chromatin assembly factor 1 subunit A Source.172: DFBPPR19326 ---- Animal proteins ---- Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 Source.173: DFBPPR19494 ---- Animal proteins ---- Ganglioside-induced differentiation-associated protein 1 Source.174: DFBPPR19500 ---- Animal proteins ---- Complement C2 Source.175: DFBPPR19504 ---- Animal proteins ---- Cytosolic Fe-S cluster assembly factor NUBP2 Source.176: DFBPPR19528 ---- Animal proteins ---- Methionine--tRNA ligase, cytoplasmic Source.177: DFBPPR19565 ---- Animal proteins ---- 26S proteasome non-ATPase regulatory subunit 4 Source.178: DFBPPR19571 ---- Animal proteins ---- Tonsoku-like protein Source.179: DFBPPR19612 ---- Animal proteins ---- Lysosomal-trafficking regulator Source.180: DFBPPR19767 ---- Animal proteins ---- F-box/LRR-repeat protein 15 Source.181: DFBPPR19783 ---- Animal proteins ---- Syndecan-1 Source.182: DFBPPR19941 ---- Animal proteins ---- MAGUK p55 subfamily member 7 Source.183: DFBPPR19977 ---- Animal proteins ---- Probable ATP-dependent RNA helicase DDX27 Source.184: DFBPPR20103 ---- Animal proteins ---- Protein MAL2 Source.185: DFBPPR20227 ---- Animal proteins ---- 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase Source.186: DFBPPR20428 ---- Animal proteins ---- Rab effector Noc2 Source.187: DFBPPR20447 ---- Animal proteins ---- BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 Source.188: DFBPPR20473 ---- Animal proteins ---- Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Source.189: DFBPPR20486 ---- Animal proteins ---- Ethanolamine-phosphate phospho-lyase Source.190: DFBPPR20573 ---- Animal proteins ---- T-complex protein 1 subunit delta Source.191: DFBPPR20670 ---- Animal proteins ---- Conserved oligomeric Golgi complex subunit 4 Source.192: DFBPPR20715 ---- Animal proteins ---- SLAIN motif-containing protein 2 Source.193: DFBPPR20850 ---- Animal proteins ---- Arylsulfatase K Source.194: DFBPPR20918 ---- Animal proteins ---- Histidine ammonia-lyase Source.195: DFBPPR21042 ---- Animal proteins ---- Kelch-like protein 21 Source.196: DFBPPR21177 ---- Animal proteins ---- Ran guanine nucleotide release factor Source.197: DFBPPR21232 ---- Animal proteins ---- Cerebellin-3 Source.198: DFBPPR21461 ---- Animal proteins ---- Glycerate kinase Source.199: DFBPPR21483 ---- Animal proteins ---- F-box/LRR-repeat protein 8 Source.200: DFBPPR21522 ---- Animal proteins ---- ATP-dependent RNA helicase DQX1 Source.201: DFBPPR21561 ---- Animal proteins ---- Vesicle-trafficking protein SEC22c Source.202: DFBPPR21569 ---- Animal proteins ---- Engulfment and cell motility protein 3 Source.203: DFBPPR21692 ---- Animal proteins ---- Mitotic-spindle organizing protein 2 Source.204: DFBPPR21712 ---- Animal proteins ---- Serpin E3 Source.205: DFBPPR21801 ---- Animal proteins ---- Cell cycle checkpoint control protein RAD9B Source.206: DFBPPR21802 ---- Animal proteins ---- Antigen WC1.1 Source.207: DFBPPR21814 ---- Animal proteins ---- Vacuolar fusion protein MON1 homolog A Source.208: DFBPPR21827 ---- Animal proteins ---- LETM1 domain-containing protein 1 Source.209: DFBPPR21867 ---- Animal proteins ---- Ankyrin repeat and SOCS box protein 5 Source.210: DFBPPR21879 ---- Animal proteins ---- Protein SDA1 homolog Source.211: DFBPPR21921 ---- Animal proteins ---- AP-5 complex subunit beta-1 Source.212: DFBPPR22018 ---- Animal proteins ---- Armadillo repeat-containing protein 1 Source.213: DFBPPR22037 ---- Animal proteins ---- Metallo-beta-lactamase domain-containing protein 2 Source.214: DFBPPR22039 ---- Animal proteins ---- T-complex protein 1 subunit zeta-2 Source.215: DFBPPR22119 ---- Animal proteins ---- Transmembrane protein with metallophosphoesterase domain Source.216: DFBPPR22162 ---- Animal proteins ---- Transmembrane protein 245 Source.217: DFBPPR22181 ---- Animal proteins ---- Tigger transposable element-derived protein 5 Source.218: DFBPPR22219 ---- Animal proteins ---- EF-hand and coiled-coil domain-containing protein 1 Source.219: DFBPPR22265 ---- Animal proteins ---- Protein KTI12 homolog Source.220: DFBPPR22301 ---- Animal proteins ---- Transmembrane protein 184B Source.221: DFBPPR22518 ---- Animal proteins ---- NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 Source.222: DFBPPR22633 ---- Animal proteins ---- Transmembrane protein 270 Source.223: DFBPPR8543 ---- Animal proteins ---- Sterol regulatory element-binding protein 1 Source.224: DFBPPR8575 ---- Animal proteins ---- Tyrosine-protein kinase JAK2 Source.225: DFBPPR8672 ---- Animal proteins ---- Fatty-acid amide hydrolase 1 Source.226: DFBPPR8677 ---- Animal proteins ---- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Source.227: DFBPPR8705 ---- Animal proteins ---- Unconventional myosin-VI Source.228: DFBPPR8712 ---- Animal proteins ---- Interferon-induced GTP-binding protein Mx2 Source.229: DFBPPR8767 ---- Animal proteins ---- Lutropin-choriogonadotropic hormone receptor Source.230: DFBPPR8885 ---- Animal proteins ---- Cholesterol side-chain cleavage enzyme, mitochondrial Source.231: DFBPPR8923 ---- Animal proteins ---- Cubilin Source.232: DFBPPR8981 ---- Animal proteins ---- Deleted in malignant brain tumors 1 protein Source.233: DFBPPR9360 ---- Animal proteins ---- Oxytocin receptor Source.234: DFBPPR9871 ---- Animal proteins ---- DNA-binding protein inhibitor ID-4 Source.235: DFBPPR9999 ---- Animal proteins ---- Apoptosis regulator Bcl-2 Source.236: DFBPPR10007 ---- Animal proteins ---- Protein Wnt-1 Source.237: DFBPPR10111 ---- Animal proteins ---- Hematopoietic prostaglandin D synthase Source.238: DFBPPR10128 ---- Animal proteins ---- Focal adhesion kinase 1 Source.239: DFBPPR10381 ---- Animal proteins ---- ATP-dependent RNA helicase SUPV3L1, mitochondrial Source.240: DFBPPR10411 ---- Animal proteins ---- DNA-dependent protein kinase catalytic subunit Source.241: DFBPPR10476 ---- Animal proteins ---- CAP-Gly domain-containing linker protein 1 Source.242: DFBPPR10661 ---- Animal proteins ---- Receptor-type tyrosine-protein phosphatase U Source.243: DFBPPR10690 ---- Animal proteins ---- V(D)J recombination-activating protein 1 Source.244: DFBPPR10851 ---- Animal proteins ---- Wee1-like protein kinase 2 Source.245: DFBPPR10852 ---- Animal proteins ---- Wee1-like protein kinase 2 Source.246: DFBPPR10870 ---- Animal proteins ---- NAD(P)(+)--arginine ADP-ribosyltransferase 2 Source.247: DFBPPR10889 ---- Animal proteins ---- NAD(P)(+)--arginine ADP-ribosyltransferase 1 Source.248: DFBPPR10940 ---- Animal proteins ---- Protein piccolo Source.249: DFBPPR11017 ---- Animal proteins ---- Collectin-12 Source.250: DFBPPR11018 ---- Animal proteins ---- Transcriptional coactivator YAP1 Source.251: DFBPPR11089 ---- Animal proteins ---- Endosomal/lysosomal potassium channel TMEM175 Source.252: DFBPPR11210 ---- Animal proteins ---- UbiA prenyltransferase domain-containing protein 1 Source.253: DFBPPR11264 ---- Animal proteins ---- Charged multivesicular body protein 7 Source.254: DFBPPR11605 ---- Animal proteins ---- DNA repair protein complementing XP-A cells homolog Source.255: DFBPPR11667 ---- Animal proteins ---- Heme transporter HRG1 Source.256: DFBPPR11679 ---- Animal proteins ---- Spondin-1 Source.257: DFBPPR11708 ---- Animal proteins ---- Phosphoinositide 3-kinase regulatory subunit 5 Source.258: DFBPPR12116 ---- Animal proteins ---- Armadillo repeat-containing protein 1 Source.259: DFBPPR12290 ---- Animal proteins ---- Ryanodine receptor 2 Source.260: DFBPPR12313 ---- Animal proteins ---- Probable phospholipid-transporting ATPase IF Source.261: DFBPPR12410 ---- Animal proteins ---- Secretory phospholipase A2 receptor Source.262: DFBPPR12489 ---- Animal proteins ---- Monocyte differentiation antigen CD14 Source.263: DFBPPR12494 ---- Animal proteins ---- V(D)J recombination-activating protein 1 Source.264: DFBPPR12526 ---- Animal proteins ---- Solute carrier family 2, facilitated glucose transporter member 5 Source.265: DFBPPR12592 ---- Animal proteins ---- Amiloride-sensitive sodium channel subunit beta Source.266: DFBPPR12781 ---- Animal proteins ---- Melanotransferrin Source.267: DFBPPR12846 ---- Animal proteins ---- NEDD8 Source.268: DFBPPR12896 ---- Animal proteins ---- T-lymphocyte activation antigen CD80 Source.269: DFBPPR12944 ---- Animal proteins ---- Multidrug and toxin extrusion protein 1 Source.270: DFBPPR13029 ---- Animal proteins ---- Ankyrin repeat and SOCS box protein 5 Source.271: DFBPPR13550 ---- Animal proteins ---- Corticotropin-releasing factor-binding protein Source.272: DFBPPR13782 ---- Animal proteins ---- BMP and activin membrane-bound inhibitor homolog Source.273: DFBPPR13848 ---- Animal proteins ---- Oxytocin receptor Source.274: DFBPPR14398 ---- Marine protein ---- 30S ribosomal protein S7, chloroplastic Source.275: DFBPPR14401 ---- Marine protein ---- 50S ribosomal protein L4, chloroplastic Source.276: DFBPPR14555 ---- Marine protein ---- Vitellogenin Source.277: DFBPPR14572 ---- Marine protein ---- V(D)J recombination-activating protein 1 Source.278: DFBPPR14853 ---- Marine protein ---- Sarcoplasmic calcium-binding protein 1 Source.279: DFBPPR14981 ---- Microorganism protein ---- Enolase-phosphatase E1 Source.280: DFBPPR15007 ---- Microorganism protein ---- Vacuolar protein 8 Source.281: DFBPPR15174 ---- Microorganism protein ---- ATP-dependent rRNA helicase RRP3 Source.282: DFBPPR15198 ---- Microorganism protein ---- tRNA:m(4)X modification enzyme TRM13 Source.283: DFBPPR15344 ---- Microorganism protein ---- Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial Source.284: DFBPPR15363 ---- Microorganism protein ---- Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial Source.285: DFBPPR15415 ---- Microorganism protein ---- Transcription initiation factor TFIID subunit 4 Source.286: DFBPPR15422 ---- Microorganism protein ---- Probable DNA-directed RNA polymerase Source.287: DFBPPR15657 ---- Microorganism protein ---- COP9 signalosome complex subunit 11 Source.288: DFBPPR7864 ---- Plant protein ---- ATP synthase epsilon chain, chloroplastic Source.289: DFBPPR7874 ---- Plant protein ---- CASP-like protein 1D1 Source.290: DFBPPR8009 ---- Plant protein ---- CASP-like protein 5B1 Source.291: DFBPPR8012 ---- Plant protein ---- CASP-like protein 5A1 Source.292: DFBPPR8120 ---- Plant protein ---- Protein TIC 214 Source.293: DFBPPR8307 ---- Plant protein ---- ATP synthase epsilon chain, chloroplastic
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

ACE-inhibitory activity	The peptide exhibited very low Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) inhibitory activity with an IC₅₀ value of 1268 uM.
Specific target protein(s)	Specific Target Protein(s): Angiotensin-converting enzyme

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Bitter taste ^prediction

SMILES

N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

Preparation method

Mode of preparation	Enzymatic hydrolysis
Enzyme(s)/starter culture	The M. veneriformis proteins were hydrolyzed by incubating with trypsin at pH 8.5 for 2 h at 40 ℃ at an enzyme to substrate ratio of 0.60% (w/w).

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Liu R, Zhu Y, Chen J, Wu H, Shi L, Wang X, Wang L. Characterization of ACE inhibitory peptides from Mactra veneriformis hydrolysate by nano-liquid chromatography electrospray ionization mass spectrometry (Nano-LC-ESI-MS) and molecular docking. Mar Drugs. 2014 Jun 30;12(7):3917-28. PMID: 24983637 DOI: 10.3390/md12073917
Other literature(s)	N.D
PubDate	2014