Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPACEI1823(ACE-inhibitory peptide)

DFBP ID	DFBPACEI1823
Peptide sequence	DTW
Type	Native peptide
Peptide/Function name	ACE-inhibitory peptide

Function-activity relationship

Main bioactivity	ACE-inhibitory activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

Asp-Thr-Trp

Single-letter amino acid

DTW

Peptide length

Peptide mass

Experimental mass	Theoretical mass
420 Da	420.42 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

3.13 ^c

IC₅₀

260 ± 26 μM

pIC₅₀

-2.415

GRAVY

-1.7000^c

Hydrophilic residue ratio

33.33%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Plant
Organism/Source	Chlorella vulgaris (C. vulgaris)
Precursor protein	Photosystem II CP43 reaction center protein (P56308)
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR0850 ---- Plant proteins ---- Calcium-dependent protein kinase 7 Source.2: DFBPPR0927 ---- Plant proteins ---- Serine/threonine-protein kinase TOR Source.3: DFBPPR1087 ---- Plant proteins ---- Protein TPR1 Source.4: DFBPPR1252 ---- Plant proteins ---- CBL-interacting protein kinase 24 Source.5: DFBPPR1303 ---- Plant proteins ---- Inositol-tetrakisphosphate 1-kinase 6 Source.6: DFBPPR1344 ---- Plant proteins ---- Probable glutamate carboxypeptidase PLA3 Source.7: DFBPPR1391 ---- Plant proteins ---- DNA (cytosine-5)-methyltransferase CMT3 Source.8: DFBPPR1499 ---- Plant proteins ---- Protein kinase and PP2C-like domain-containing protein Source.9: DFBPPR1587 ---- Plant proteins ---- CBL-interacting protein kinase 8 Source.10: DFBPPR1678 ---- Plant proteins ---- Mitogen-activated protein kinase 7 Source.11: DFBPPR2008 ---- Plant proteins ---- Putative MYST-like histone acetyltransferase 1 Source.12: DFBPPR2109 ---- Plant proteins ---- DNA (cytosine-5)-methyltransferase CMT1 Source.13: DFBPPR2120 ---- Plant proteins ---- Putative cyclin-dependent kinase F-2 Source.14: DFBPPR2170 ---- Plant proteins ---- Signal peptide peptidase-like 3 Source.15: DFBPPR2304 ---- Plant proteins ---- Photosystem II CP43 reaction center protein Source.16: DFBPPR2363 ---- Plant proteins ---- DEAD-box ATP-dependent RNA helicase 30 Source.17: DFBPPR2502 ---- Plant proteins ---- E3 ubiquitin-protein ligase Os04g0590900 Source.18: DFBPPR2592 ---- Plant proteins ---- DNA (cytosine-5)-methyltransferase CMT2 Source.19: DFBPPR2642 ---- Plant proteins ---- CBL-interacting protein kinase 18 Source.20: DFBPPR2803 ---- Plant proteins ---- Putative mannan endo-1,4-beta-mannosidase 5 Source.21: DFBPPR2916 ---- Plant proteins ---- Pseudo histidine-containing phosphotransfer protein 1 Source.22: DFBPPR2959 ---- Plant proteins ---- Serine/threonine-protein phosphatase BSL2 homolog Source.23: DFBPPR3054 ---- Plant proteins ---- Pectinesterase inhibitor 8 Source.24: DFBPPR3082 ---- Plant proteins ---- 4-alpha-glucanotransferase DPE2 Source.25: DFBPPR3092 ---- Plant proteins ---- Beta-galactosidase 12 Source.26: DFBPPR3093 ---- Plant proteins ---- Beta-galactosidase 11 Source.27: DFBPPR3252 ---- Plant proteins ---- Probable protein phosphatase 2C 70 Source.28: DFBPPR3481 ---- Plant proteins ---- PHD finger protein ALFIN-LIKE 8 Source.29: DFBPPR3522 ---- Plant proteins ---- Probable protein phosphatase 2C 56 Source.30: DFBPPR3718 ---- Plant proteins ---- Expansin-like B1 Source.31: DFBPPR3767 ---- Plant proteins ---- Mannan endo-1,4-beta-mannosidase 8 Source.32: DFBPPR3958 ---- Plant proteins ---- Probable U6 snRNA-associated Sm-like protein LSm4 Source.33: DFBPPR4029 ---- Plant proteins ---- Putative multidrug resistance protein Source.34: DFBPPR4243 ---- Plant proteins ---- UDP-glucose:2-hydroxyflavanone C-glucosyltransferase Source.35: DFBPPR4431 ---- Plant proteins ---- Spindle and kinetochore-associated protein 1 homolog Source.36: DFBPPR4555 ---- Plant proteins ---- Actin-related protein 9 Source.37: DFBPPR4875 ---- Plant proteins ---- Putative zinc finger CCCH domain-containing protein 64 Source.38: DFBPPR4912 ---- Plant proteins ---- Probable xyloglucan 6-xylosyltransferase 1 Source.39: DFBPPR5092 ---- Plant proteins ---- Glutathione S-transferase 3 Source.40: DFBPPR5120 ---- Plant proteins ---- 17.3 kDa class I heat shock protein Source.41: DFBPPR5123 ---- Plant proteins ---- Photosystem II CP43 reaction center protein Source.42: DFBPPR5131 ---- Plant proteins ---- 17.5 kDa class I heat shock protein Source.43: DFBPPR5132 ---- Plant proteins ---- 18.5 kDa class I heat shock protein Source.44: DFBPPR5143 ---- Plant proteins ---- 17.5 kDa class I heat shock protein Source.45: DFBPPR5157 ---- Plant proteins ---- 17.6 kDa class I heat shock protein Source.46: DFBPPR5158 ---- Plant proteins ---- Class I heat shock protein Source.47: DFBPPR5165 ---- Plant proteins ---- DNA-directed RNA polymerase subunit beta'' Source.48: DFBPPR5277 ---- Plant proteins ---- Cytochrome P450 97B2, chloroplastic Source.49: DFBPPR5436 ---- Plant proteins ---- Probable glutamate carboxypeptidase VP8 Source.50: DFBPPR5530 ---- Plant proteins ---- Photosystem II CP43 reaction center protein Source.51: DFBPPR5590 ---- Plant proteins ---- Probable serine/threonine-protein kinase CCRP1 Source.52: DFBPPR5631 ---- Plant proteins ---- DNA (cytosine-5)-methyltransferase 1 Source.53: DFBPPR5637 ---- Plant proteins ---- Beta-fructofuranosidase 1 Source.54: DFBPPR5813 ---- Plant proteins ---- DNA (cytosine-5)-methyltransferase 2 Source.55: DFBPPR5832 ---- Plant proteins ---- DNA (cytosine-5)-methyltransferase 3 Source.56: DFBPPR6045 ---- Plant proteins ---- Spindle and kinetochore-associated protein 1 homolog Source.57: DFBPPR6214 ---- Plant proteins ---- Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic Source.58: DFBPPR6278 ---- Plant proteins ---- Protein TIC 55, chloroplastic Source.59: DFBPPR6340 ---- Plant proteins ---- Photosystem II CP43 reaction center protein Source.60: DFBPPR6772 ---- Plant proteins ---- Photosystem II CP43 reaction center protein Source.61: DFBPPR7105 ---- Plant proteins ---- Photosystem II CP43 reaction center protein Source.62: DFBPPR7149 ---- Plant proteins ---- Granule-bound starch synthase 1b, chloroplastic/amyloplastic Source.63: DFBPPR7193 ---- Plant proteins ---- Endoplasmin homolog Source.64: DFBPPR7430 ---- Plant proteins ---- Nitrate reductase [NADH], clone PBNBR1412 Source.65: DFBPPR7607 ---- Milk proteins ---- Galectin-3-binding protein Source.66: DFBPPR8188 ---- Plant proteins ---- Nitrate reductase [NADH] Source.67: DFBPPR8454 ---- Plant proteins ---- Photosystem II CP43 reaction center protein Source.68: DFBPPR15996 ---- Animal proteins ---- Calcium-activated potassium channel subunit alpha-1 Source.69: DFBPPR16099 ---- Animal proteins ---- Alpha-ketoglutarate-dependent dioxygenase FTO Source.70: DFBPPR16144 ---- Animal proteins ---- Tight junction protein ZO-3 Source.71: DFBPPR16148 ---- Animal proteins ---- Haptoglobin Source.72: DFBPPR16197 ---- Animal proteins ---- Cytochrome c oxidase subunit 1 Source.73: DFBPPR16211 ---- Animal proteins ---- Lysine-specific demethylase 5C Source.74: DFBPPR16232 ---- Animal proteins ---- Lysine-specific demethylase 5D Source.75: DFBPPR16268 ---- Animal proteins ---- Tissue alpha-L-fucosidase Source.76: DFBPPR16285 ---- Animal proteins ---- Chymase Source.77: DFBPPR16342 ---- Animal proteins ---- cGMP-gated cation channel alpha-1 Source.78: DFBPPR16343 ---- Animal proteins ---- cGMP-gated cation channel alpha-1 Source.79: DFBPPR16456 ---- Animal proteins ---- Ribosome-binding protein 1 Source.80: DFBPPR16499 ---- Animal proteins ---- Tumor necrosis factor receptor superfamily member 5 Source.81: DFBPPR16599 ---- Animal proteins ---- Receptor-binding cancer antigen expressed on SiSo cells Source.82: DFBPPR16622 ---- Animal proteins ---- EGF domain-specific O-linked N-acetylglucosamine transferase Source.83: DFBPPR16748 ---- Animal proteins ---- Thyroid adenoma-associated protein homolog Source.84: DFBPPR16817 ---- Animal proteins ---- Cytochrome c oxidase subunit 1 Source.85: DFBPPR16836 ---- Animal proteins ---- Fibronectin Source.86: DFBPPR16846 ---- Animal proteins ---- Chitinase-3-like protein 1 Source.87: DFBPPR16955 ---- Animal proteins ---- Aldo-keto reductase family 1 member B1 Source.88: DFBPPR17096 ---- Animal proteins ---- Activated CDC42 kinase 1 Source.89: DFBPPR17099 ---- Animal proteins ---- cGMP-gated cation channel alpha-1 Source.90: DFBPPR17110 ---- Animal proteins ---- Diacylglycerol O-acyltransferase 2 Source.91: DFBPPR17137 ---- Animal proteins ---- Interleukin-1 receptor-associated kinase 1 Source.92: DFBPPR17272 ---- Animal proteins ---- Dysbindin Source.93: DFBPPR17284 ---- Animal proteins ---- Calcium-activated potassium channel subunit alpha-1 Source.94: DFBPPR17296 ---- Animal proteins ---- Dynamin-2 Source.95: DFBPPR17304 ---- Animal proteins ---- Endoplasmic reticulum membrane sensor NFE2L1 Source.96: DFBPPR17320 ---- Animal proteins ---- Acid ceramidase Source.97: DFBPPR17476 ---- Animal proteins ---- Heterogeneous nuclear ribonucleoprotein K Source.98: DFBPPR17479 ---- Animal proteins ---- Ubiquitin carboxyl-terminal hydrolase 13 Source.99: DFBPPR17490 ---- Animal proteins ---- TIR domain-containing adapter molecule 2 Source.100: DFBPPR17571 ---- Animal proteins ---- Proton-coupled folate transporter Source.101: DFBPPR17748 ---- Animal proteins ---- Interleukin-12 subunit beta Source.102: DFBPPR17910 ---- Animal proteins ---- Mitogen-activated protein kinase kinase kinase 13 Source.103: DFBPPR17987 ---- Animal proteins ---- DCN1-like protein 3 Source.104: DFBPPR17988 ---- Animal proteins ---- Poly(A)-specific ribonuclease PARN Source.105: DFBPPR18031 ---- Animal proteins ---- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 Source.106: DFBPPR18059 ---- Animal proteins ---- Ubiquitin thioesterase OTU1 Source.107: DFBPPR18129 ---- Animal proteins ---- Ubiquitin carboxyl-terminal hydrolase 15 Source.108: DFBPPR18150 ---- Animal proteins ---- Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 Source.109: DFBPPR18362 ---- Animal proteins ---- Cyclic nucleotide-gated olfactory channel Source.110: DFBPPR18365 ---- Animal proteins ---- Glutamyl aminopeptidase Source.111: DFBPPR18368 ---- Animal proteins ---- E3 ubiquitin-protein ligase TRIP12 Source.112: DFBPPR18456 ---- Animal proteins ---- Beta-crystallin B1 Source.113: DFBPPR18461 ---- Animal proteins ---- Glutamine--tRNA ligase Source.114: DFBPPR18476 ---- Animal proteins ---- Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 Source.115: DFBPPR18517 ---- Animal proteins ---- Scavenger receptor cysteine-rich type 1 protein M130 Source.116: DFBPPR18609 ---- Animal proteins ---- ERO1-like protein alpha Source.117: DFBPPR18699 ---- Animal proteins ---- Lysyl oxidase homolog 4 Source.118: DFBPPR18704 ---- Animal proteins ---- Phosphatidylinositol-3-phosphatase SAC1 Source.119: DFBPPR18824 ---- Animal proteins ---- Hydroxymethylglutaryl-CoA synthase, mitochondrial Source.120: DFBPPR18868 ---- Animal proteins ---- Haptoglobin Source.121: DFBPPR18901 ---- Animal proteins ---- Nuclear factor of activated T-cells, cytoplasmic 1 Source.122: DFBPPR18902 ---- Animal proteins ---- Plasmanylethanolamine desaturase Source.123: DFBPPR18958 ---- Animal proteins ---- Cysteine-rich PDZ-binding protein Source.124: DFBPPR19075 ---- Animal proteins ---- Ubiquitin-conjugating enzyme E2 J2 Source.125: DFBPPR19216 ---- Animal proteins ---- Cysteine protease ATG4B Source.126: DFBPPR19244 ---- Animal proteins ---- Cell division cycle protein 23 homolog Source.127: DFBPPR19269 ---- Animal proteins ---- HCLS1-associated protein X-1 Source.128: DFBPPR19390 ---- Animal proteins ---- E3 ubiquitin-protein ligase TM129 Source.129: DFBPPR19452 ---- Animal proteins ---- Mitochondrial amidoxime reducing component 2 Source.130: DFBPPR19537 ---- Animal proteins ---- CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial Source.131: DFBPPR19606 ---- Animal proteins ---- Ornithine carbamoyltransferase, mitochondrial Source.132: DFBPPR19614 ---- Animal proteins ---- Putative glycerol kinase 5 Source.133: DFBPPR19715 ---- Animal proteins ---- Chorionic somatomammotropin hormone 2 Source.134: DFBPPR19730 ---- Animal proteins ---- Tensin-1 Source.135: DFBPPR19789 ---- Animal proteins ---- Glutamate decarboxylase 1 Source.136: DFBPPR19825 ---- Animal proteins ---- DNA excision repair protein ERCC-6-like 2 Source.137: DFBPPR20047 ---- Animal proteins ---- Tumor necrosis factor receptor superfamily member 11B Source.138: DFBPPR20270 ---- Animal proteins ---- EGF domain-specific O-linked N-acetylglucosamine transferase Source.139: DFBPPR20299 ---- Animal proteins ---- AP-5 complex subunit mu-1 Source.140: DFBPPR20708 ---- Animal proteins ---- Growth arrest and DNA damage-inducible protein GADD45 beta Source.141: DFBPPR20768 ---- Animal proteins ---- Lysozyme-like protein 1 Source.142: DFBPPR20803 ---- Animal proteins ---- NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 Source.143: DFBPPR20818 ---- Animal proteins ---- Protein-lysine N-methyltransferase EEF2KMT Source.144: DFBPPR20855 ---- Animal proteins ---- Diphthine methyl ester synthase Source.145: DFBPPR20968 ---- Animal proteins ---- Ras GTPase-activating protein 3 Source.146: DFBPPR20989 ---- Animal proteins ---- Ubiquinone biosynthesis protein COQ9, mitochondrial Source.147: DFBPPR21007 ---- Animal proteins ---- Protein ABHD1 Source.148: DFBPPR21120 ---- Animal proteins ---- Intraflagellar transport protein 46 homolog Source.149: DFBPPR21150 ---- Animal proteins ---- DnaJ homolog subfamily C member 27 Source.150: DFBPPR21190 ---- Animal proteins ---- Coiled-coil domain-containing protein 22 Source.151: DFBPPR21284 ---- Animal proteins ---- Tetratricopeptide repeat protein 30B Source.152: DFBPPR21306 ---- Animal proteins ---- Protein ATP1B4 Source.153: DFBPPR21386 ---- Animal proteins ---- Protein phosphatase 1 regulatory subunit 3B Source.154: DFBPPR21402 ---- Animal proteins ---- Pyridoxal phosphate phosphatase PHOSPHO2 Source.155: DFBPPR21413 ---- Animal proteins ---- Protein kinase C-binding protein NELL2 Source.156: DFBPPR21552 ---- Animal proteins ---- SPRY domain-containing SOCS box protein 3 Source.157: DFBPPR21573 ---- Animal proteins ---- Tetratricopeptide repeat protein 30A Source.158: DFBPPR21723 ---- Animal proteins ---- OCIA domain-containing protein 1 Source.159: DFBPPR22047 ---- Animal proteins ---- WD repeat-containing protein 6 Source.160: DFBPPR22071 ---- Animal proteins ---- Neuromedin-S Source.161: DFBPPR22123 ---- Animal proteins ---- Protein KRI1 homolog Source.162: DFBPPR22296 ---- Animal proteins ---- Kelch domain-containing protein 2 Source.163: DFBPPR22468 ---- Animal proteins ---- Queuosine salvage protein Source.164: DFBPPR8550 ---- Animal proteins ---- Complement C3 Source.165: DFBPPR8587 ---- Animal proteins ---- Aldo-keto reductase family 1 member A1 Source.166: DFBPPR8596 ---- Animal proteins ---- Gelsolin Source.167: DFBPPR8646 ---- Animal proteins ---- Chitinase-3-like protein 1 Source.168: DFBPPR8660 ---- Animal proteins ---- Interleukin-12 subunit beta Source.169: DFBPPR8661 ---- Animal proteins ---- Calcium-activated potassium channel subunit alpha-1 Source.170: DFBPPR8802 ---- Animal proteins ---- Insulin-like growth factor II Source.171: DFBPPR8804 ---- Animal proteins ---- 1,5-anhydro-D-fructose reductase Source.172: DFBPPR8841 ---- Animal proteins ---- Glutamyl aminopeptidase Source.173: DFBPPR8842 ---- Animal proteins ---- Kelch-like ECH-associated protein 1 Source.174: DFBPPR8865 ---- Animal proteins ---- Haptoglobin Source.175: DFBPPR8951 ---- Animal proteins ---- ERO1-like protein alpha Source.176: DFBPPR8952 ---- Animal proteins ---- ERO1-like protein alpha Source.177: DFBPPR9062 ---- Animal proteins ---- Methylsterol monooxygenase 1 Source.178: DFBPPR9102 ---- Animal proteins ---- Nuclear factor of activated T-cells, cytoplasmic 1 Source.179: DFBPPR9105 ---- Animal proteins ---- Lysine-specific demethylase 5C Source.180: DFBPPR9183 ---- Animal proteins ---- Glutamate decarboxylase 1 Source.181: DFBPPR9216 ---- Animal proteins ---- Netrin-1 Source.182: DFBPPR9232 ---- Animal proteins ---- Ornithine carbamoyltransferase, mitochondrial Source.183: DFBPPR9244 ---- Animal proteins ---- Krueppel-like factor 9 Source.184: DFBPPR9309 ---- Animal proteins ---- Sperm flagellar protein 2 Source.185: DFBPPR9358 ---- Animal proteins ---- Hydroxymethylglutaryl-CoA synthase, mitochondrial Source.186: DFBPPR9387 ---- Animal proteins ---- Protein ATP1B4 Source.187: DFBPPR9687 ---- Animal proteins ---- Beta-crystallin B1 Source.188: DFBPPR9746 ---- Animal proteins ---- Valine--tRNA ligase, mitochondrial Source.189: DFBPPR9764 ---- Animal proteins ---- Cationic amino acid transporter 2 Source.190: DFBPPR9860 ---- Animal proteins ---- Transcription factor 19 Source.191: DFBPPR9966 ---- Animal proteins ---- Ornithine carbamoyltransferase, mitochondrial Source.192: DFBPPR10025 ---- Animal proteins ---- Major prion protein homolog Source.193: DFBPPR10057 ---- Animal proteins ---- Stimulator of interferon genes protein Source.194: DFBPPR10078 ---- Animal proteins ---- Calcium-activated potassium channel subunit alpha-1 Source.195: DFBPPR10155 ---- Animal proteins ---- Cationic amino acid transporter 2 Source.196: DFBPPR10162 ---- Animal proteins ---- Dynamin-like 120 kDa protein, mitochondrial Source.197: DFBPPR10183 ---- Animal proteins ---- Villin-1 Source.198: DFBPPR10224 ---- Animal proteins ---- Prolyl 3-hydroxylase 1 Source.199: DFBPPR10230 ---- Animal proteins ---- B-cell linker protein Source.200: DFBPPR10300 ---- Animal proteins ---- Unconventional myosin-Va Source.201: DFBPPR10484 ---- Animal proteins ---- Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe Source.202: DFBPPR10556 ---- Animal proteins ---- Tenascin-R Source.203: DFBPPR10646 ---- Animal proteins ---- Netrin-1 Source.204: DFBPPR10650 ---- Animal proteins ---- Gelsolin Source.205: DFBPPR10703 ---- Animal proteins ---- Tensin Source.206: DFBPPR10913 ---- Animal proteins ---- Myocyte-specific enhancer factor 2A Source.207: DFBPPR11082 ---- Animal proteins ---- Protein-glucosylgalactosylhydroxylysine glucosidase Source.208: DFBPPR11203 ---- Animal proteins ---- Cyclic nucleotide-gated channel rod photoreceptor subunit alpha Source.209: DFBPPR11262 ---- Animal proteins ---- Cysteine protease ATG4B Source.210: DFBPPR11296 ---- Animal proteins ---- Aldo-keto reductase family 1 member A1 Source.211: DFBPPR11341 ---- Animal proteins ---- CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial Source.212: DFBPPR11431 ---- Animal proteins ---- Putative glycerol kinase 5 Source.213: DFBPPR11489 ---- Animal proteins ---- Beta-crystallin B1 Source.214: DFBPPR11678 ---- Animal proteins ---- Protein ABHD13 Source.215: DFBPPR11682 ---- Animal proteins ---- DCN1-like protein 1 Source.216: DFBPPR11805 ---- Animal proteins ---- Tudor domain-containing protein 3 Source.217: DFBPPR12078 ---- Animal proteins ---- Transmembrane protein 129 Source.218: DFBPPR12089 ---- Animal proteins ---- Cysteine-rich PDZ-binding protein Source.219: DFBPPR12165 ---- Animal proteins ---- Vacuolar fusion protein MON1 homolog A Source.220: DFBPPR12277 ---- Animal proteins ---- Calcium-activated potassium channel subunit alpha-1 Source.221: DFBPPR12374 ---- Animal proteins ---- Sortilin-related receptor Source.222: DFBPPR12391 ---- Animal proteins ---- Aldo-keto reductase family 1 member B1 Source.223: DFBPPR12422 ---- Animal proteins ---- Voltage-dependent R-type calcium channel subunit alpha-1E Source.224: DFBPPR12472 ---- Animal proteins ---- Prostaglandin E2 receptor EP4 subtype Source.225: DFBPPR12491 ---- Animal proteins ---- Matrix metalloproteinase-9 Source.226: DFBPPR12514 ---- Animal proteins ---- Transmembrane protein 109 Source.227: DFBPPR12577 ---- Animal proteins ---- Heterogeneous nuclear ribonucleoprotein K Source.228: DFBPPR12582 ---- Animal proteins ---- Cyclic nucleotide-gated olfactory channel Source.229: DFBPPR12610 ---- Animal proteins ---- Cyclin-dependent kinase 14 Source.230: DFBPPR12642 ---- Animal proteins ---- Haptoglobin Source.231: DFBPPR12643 ---- Animal proteins ---- Haptoglobin Source.232: DFBPPR12802 ---- Animal proteins ---- Complement C3 alpha chain Source.233: DFBPPR12833 ---- Animal proteins ---- Cullin-5 Source.234: DFBPPR12884 ---- Animal proteins ---- Extracellular superoxide dismutase [Cu-Zn] Source.235: DFBPPR12937 ---- Animal proteins ---- Zonadhesin Source.236: DFBPPR12985 ---- Animal proteins ---- Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 Source.237: DFBPPR13065 ---- Animal proteins ---- Tartrate-resistant acid phosphatase type 5 Source.238: DFBPPR13149 ---- Animal proteins ---- Tumor necrosis factor receptor superfamily member 5 Source.239: DFBPPR13190 ---- Animal proteins ---- Sodium channel protein type 4 subunit alpha Source.240: DFBPPR13196 ---- Animal proteins ---- Metalloproteinase inhibitor 1 Source.241: DFBPPR13229 ---- Animal proteins ---- Gelsolin Source.242: DFBPPR13263 ---- Animal proteins ---- Serotransferrin Source.243: DFBPPR13423 ---- Animal proteins ---- Chitinase-3-like protein 1 Source.244: DFBPPR13444 ---- Animal proteins ---- Cytochrome c oxidase subunit 1 Source.245: DFBPPR13490 ---- Animal proteins ---- Interleukin-12 subunit beta Source.246: DFBPPR13534 ---- Animal proteins ---- Chitinase-3-like protein 1 Source.247: DFBPPR13595 ---- Animal proteins ---- Cytochrome c oxidase subunit 1 Source.248: DFBPPR13614 ---- Animal proteins ---- Insulin-like growth factor II Source.249: DFBPPR13616 ---- Animal proteins ---- Ornithine carbamoyltransferase, mitochondrial Source.250: DFBPPR13636 ---- Animal proteins ---- Interleukin-12 subunit beta Source.251: DFBPPR13815 ---- Animal proteins ---- Mast cell protease 2 Source.252: DFBPPR14077 ---- Marine protein ---- Serotransferrin-1 Source.253: DFBPPR14080 ---- Marine protein ---- Serotransferrin-2 Source.254: DFBPPR14293 ---- Marine protein ---- Photosystem II CP43 reaction center protein Source.255: DFBPPR14351 ---- Marine protein ---- Photosystem II CP43 reaction center protein Source.256: DFBPPR14370 ---- Marine protein ---- DNA-directed RNA polymerase subunit beta'' Source.257: DFBPPR14573 ---- Marine protein ---- Cytochrome P450 3A27 Source.258: DFBPPR14878 ---- Microorganism protein ---- Mitogen-activated protein kinase HOG1 Source.259: DFBPPR14954 ---- Microorganism protein ---- NAD(P)H-dependent D-xylose reductase Source.260: DFBPPR14955 ---- Microorganism protein ---- Serine/threonine-protein phosphatase 4 catalytic subunit Source.261: DFBPPR15017 ---- Microorganism protein ---- Serine/threonine-protein kinase TEL1 Source.262: DFBPPR15024 ---- Microorganism protein ---- Leucine aminopeptidase 2 Source.263: DFBPPR15057 ---- Microorganism protein ---- Protein transport protein SEC13 Source.264: DFBPPR15070 ---- Microorganism protein ---- Transcription factor MBP1 Source.265: DFBPPR15108 ---- Microorganism protein ---- Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial Source.266: DFBPPR15238 ---- Microorganism protein ---- Pre-mRNA-splicing factor CLF1 Source.267: DFBPPR15259 ---- Microorganism protein ---- Guanidinobutyrase Source.268: DFBPPR15284 ---- Microorganism protein ---- Sorting nexin MVP1 Source.269: DFBPPR15293 ---- Microorganism protein ---- GPI ethanolamine phosphate transferase 2 Source.270: DFBPPR15382 ---- Microorganism protein ---- Sensitive to high expression protein 9 homolog, mitochondrial Source.271: DFBPPR15465 ---- Microorganism protein ---- 2',3'-cyclic-nucleotide 3'-phosphodiesterase Source.272: DFBPPR15773 ---- Microorganism protein ---- 37S ribosomal protein S25, mitochondrial Source.273: DFBPPR15808 ---- Microorganism protein ---- Valine--tRNA ligase Source.274: DFBPPR15853 ---- Microorganism protein ---- Polyphenol oxidase 4 Source.275: DFBPPR7776 ---- Plant protein ---- Beta-sesquiphellandrene synthase Source.276: DFBPPR7793 ---- Plant protein ---- Photosystem II CP43 reaction center protein Source.277: DFBPPR8027 ---- Plant protein ---- Fe(3+)-Zn(2+) purple acid phosphatase Source.278: DFBPPR8041 ---- Plant protein ---- Nitrate reductase [NADH] 2 Source.279: DFBPPR8059 ---- Plant protein ---- Photosystem II CP43 reaction center protein Source.280: DFBPPR8237 ---- Plant protein ---- Photosystem II CP43 reaction center protein Source.281: DFBPPR8318 ---- Plant protein ---- 17.6 kDa class I heat shock protein
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

ACE-inhibitory activity	The peptide exhibited moderate Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) inhibitory activity with an IC₅₀ value of 260 ± 26 μM.
Specific target protein(s)	Specific Target Protein(s): Angiotensin-converting enzyme

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	No prediction can be made about the peptide bitterness. ^prediction

SMILES

N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)O

Preparation method

Mode of preparation	Enzymatic hydrolysis
Enzyme(s)/starter culture	The ACE inhibitory peptide was in silico screened from the product generated by virtual gastrointestinal digestion of the proteins from C. vulgaris.

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Xie J, Chen X, Wu J, Zhang Y, Zhou Y, Zhang L, Tang YJ, Wei D. Antihypertensive Effects, Molecular Docking Study, and Isothermal Titration Calorimetry Assay of Angiotensin I-Converting Enzyme Inhibitory Peptides from Chlorella vulgaris. J Agric Food Chem. 2018 Feb 14;66(6):1359-1368. PMID: 29345929 DOI: 10.1021/acs.jafc.7b04294
Other literature(s)	N.D
PubDate	2018