Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPACEI1825(ACE-inhibitory peptide)

DFBP ID	DFBPACEI1825
Peptide sequence	VVW
Type	Native peptide
Peptide/Function name	ACE-inhibitory peptide

Function-activity relationship

Main bioactivity	ACE-inhibitory activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

Val-Val-Trp

Single-letter amino acid

VVW

Peptide length

Peptide mass

Experimental mass	Theoretical mass
402 Da	402.50 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

5.97 ^c

IC₅₀

76.7 ± 10.1 μM

pIC₅₀

-1.885

GRAVY

2.5000^c

Hydrophilic residue ratio

100%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Plant
Organism/Source	Chlorella vulgaris (C. vulgaris)
Precursor protein	Photosystem I P700 chlorophyll a apoprotein A1 (P56341)
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR0869 ---- Plant proteins ---- Sucrose transport protein SUT1 Source.2: DFBPPR0937 ---- Plant proteins ---- Glutamate synthase 1 [NADH], chloroplastic Source.3: DFBPPR0998 ---- Plant proteins ---- CBL-interacting protein kinase 31 Source.4: DFBPPR1013 ---- Plant proteins ---- DNA (cytosine-5)-methyltransferase 1B Source.5: DFBPPR1027 ---- Plant proteins ---- Very-long-chain aldehyde decarbonylase GL1-2 Source.6: DFBPPR1066 ---- Plant proteins ---- Heat stress transcription factor A-2c Source.7: DFBPPR1078 ---- Plant proteins ---- Sucrose transport protein SUT5 Source.8: DFBPPR1123 ---- Plant proteins ---- Allene oxide synthase 1, chloroplastic Source.9: DFBPPR1136 ---- Plant proteins ---- Exosome complex exonuclease RRP46 homolog Source.10: DFBPPR1277 ---- Plant proteins ---- Probable cellulose synthase A catalytic subunit 8 [UDP-forming] Source.11: DFBPPR1280 ---- Plant proteins ---- Heat stress transcription factor A-2a Source.12: DFBPPR1299 ---- Plant proteins ---- Heat stress transcription factor B-4b Source.13: DFBPPR1304 ---- Plant proteins ---- Two-component response regulator ORR22 Source.14: DFBPPR1327 ---- Plant proteins ---- Heat stress transcription factor A-4d Source.15: DFBPPR1339 ---- Plant proteins ---- Glucosamine inositolphosphorylceramide transferase 1 Source.16: DFBPPR1359 ---- Plant proteins ---- Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial Source.17: DFBPPR1381 ---- Plant proteins ---- G-type lectin S-receptor-like serine/threonine-protein kinase LECRK1 Source.18: DFBPPR1408 ---- Plant proteins ---- G-type lectin S-receptor-like serine/threonine-protein kinase LECRK3 Source.19: DFBPPR1433 ---- Plant proteins ---- Cytochrome P450 714B2 Source.20: DFBPPR1436 ---- Plant proteins ---- Bidirectional sugar transporter SWEET14 Source.21: DFBPPR1452 ---- Plant proteins ---- Probable cellulose synthase A catalytic subunit 2 [UDP-forming] Source.22: DFBPPR1468 ---- Plant proteins ---- Serotonin N-acetyltransferase 2, chloroplastic Source.23: DFBPPR1475 ---- Plant proteins ---- Glutamate receptor 3.1 Source.24: DFBPPR1484 ---- Plant proteins ---- Allene oxide synthase 2 Source.25: DFBPPR1489 ---- Plant proteins ---- Protein SUBSTANDARD STARCH GRAIN 4, chloroplastic Source.26: DFBPPR1492 ---- Plant proteins ---- Cation-transporting ATPase HMA5 Source.27: DFBPPR1509 ---- Plant proteins ---- Heat stress transcription factor A-2d Source.28: DFBPPR1535 ---- Plant proteins ---- Photosystem I P700 chlorophyll a apoprotein A1 Source.29: DFBPPR1538 ---- Plant proteins ---- Heat stress transcription factor A-2e Source.30: DFBPPR1542 ---- Plant proteins ---- Very-long-chain aldehyde decarbonylase GL1-1 Source.31: DFBPPR1668 ---- Plant proteins ---- Heat stress transcription factor A-2b Source.32: DFBPPR1670 ---- Plant proteins ---- Probable beta-1,4-xylosyltransferase GT43A Source.33: DFBPPR1708 ---- Plant proteins ---- Heat stress transcription factor B-2a Source.34: DFBPPR1716 ---- Plant proteins ---- Probable AMP deaminase Source.35: DFBPPR1717 ---- Plant proteins ---- Allene oxide synthase 4 Source.36: DFBPPR1718 ---- Plant proteins ---- Allene oxide synthase 3 Source.37: DFBPPR1744 ---- Plant proteins ---- Heat stress transcription factor A-1 Source.38: DFBPPR1759 ---- Plant proteins ---- Endoribonuclease Dicer homolog 2a Source.39: DFBPPR1772 ---- Plant proteins ---- Endoribonuclease Dicer homolog 2b Source.40: DFBPPR1786 ---- Plant proteins ---- Bidirectional sugar transporter SWEET12 Source.41: DFBPPR1830 ---- Plant proteins ---- Endoribonuclease Dicer homolog 3a Source.42: DFBPPR1859 ---- Plant proteins ---- Heat stress transcription factor B-2b Source.43: DFBPPR1862 ---- Plant proteins ---- Heat stress transcription factor B-2c Source.44: DFBPPR1884 ---- Plant proteins ---- Putative laccase-1 Source.45: DFBPPR1895 ---- Plant proteins ---- DNA topoisomerase 3-alpha Source.46: DFBPPR1911 ---- Plant proteins ---- Heat stress transcription factor A-6a Source.47: DFBPPR1964 ---- Plant proteins ---- Heat stress transcription factor A-5 Source.48: DFBPPR2010 ---- Plant proteins ---- CBL-interacting protein kinase 33 Source.49: DFBPPR2016 ---- Plant proteins ---- Putative heat stress transcription factor A-6a Source.50: DFBPPR2036 ---- Plant proteins ---- Putative laccase-16 Source.51: DFBPPR2060 ---- Plant proteins ---- CBL-interacting protein kinase 3 Source.52: DFBPPR2074 ---- Plant proteins ---- Potassium transporter 7 Source.53: DFBPPR2080 ---- Plant proteins ---- Heat stress transcription factor B-1 Source.54: DFBPPR2082 ---- Plant proteins ---- Putative laccase-9 Source.55: DFBPPR2088 ---- Plant proteins ---- Probable histidine kinase 1 Source.56: DFBPPR2147 ---- Plant proteins ---- Two-component response regulator ORR23 Source.57: DFBPPR2170 ---- Plant proteins ---- Signal peptide peptidase-like 3 Source.58: DFBPPR2203 ---- Plant proteins ---- Protein SHORT-ROOT 2 Source.59: DFBPPR2210 ---- Plant proteins ---- CBL-interacting protein kinase 32 Source.60: DFBPPR2257 ---- Plant proteins ---- Probable glucomannan 4-beta-mannosyltransferase 11 Source.61: DFBPPR2291 ---- Plant proteins ---- UDP-glucose 6-dehydrogenase 3 Source.62: DFBPPR2298 ---- Plant proteins ---- UDP-glucose 6-dehydrogenase 4 Source.63: DFBPPR2310 ---- Plant proteins ---- Heat stress transcription factor A-3 Source.64: DFBPPR2328 ---- Plant proteins ---- Two-component response regulator ORR26 Source.65: DFBPPR2341 ---- Plant proteins ---- E3 ubiquitin-protein ligase Os06g0535400 Source.66: DFBPPR2367 ---- Plant proteins ---- UDP-glucose 6-dehydrogenase 5 Source.67: DFBPPR2401 ---- Plant proteins ---- Kinesin-like protein KIN-4C Source.68: DFBPPR2428 ---- Plant proteins ---- Bidirectional sugar transporter SWEET13 Source.69: DFBPPR2464 ---- Plant proteins ---- Two-component response regulator ORR25 Source.70: DFBPPR2472 ---- Plant proteins ---- Heat stress transcription factor B-4d Source.71: DFBPPR2482 ---- Plant proteins ---- Probable allantoinase Source.72: DFBPPR2527 ---- Plant proteins ---- Two-component response regulator ORR24 Source.73: DFBPPR2529 ---- Plant proteins ---- Two-component response regulator ORR21 Source.74: DFBPPR2536 ---- Plant proteins ---- Heat stress transcription factor B-4c Source.75: DFBPPR2541 ---- Plant proteins ---- Auxin response factor 18 Source.76: DFBPPR2546 ---- Plant proteins ---- Auxin response factor 1 Source.77: DFBPPR2550 ---- Plant proteins ---- Polyamine transporter PUT1 Source.78: DFBPPR2588 ---- Plant proteins ---- Putative heat stress transcription factor B-4a Source.79: DFBPPR2634 ---- Plant proteins ---- 16.0 kDa heat shock protein, peroxisomal Source.80: DFBPPR2680 ---- Plant proteins ---- Aspartic proteinase oryzasin-1 Source.81: DFBPPR2696 ---- Plant proteins ---- Probable GDP-L-fucose synthase 1 Source.82: DFBPPR2744 ---- Plant proteins ---- Zinc finger BED domain-containing protein RICESLEEPER 3 Source.83: DFBPPR2782 ---- Plant proteins ---- Thioredoxin reductase NTRA Source.84: DFBPPR2785 ---- Plant proteins ---- Aspartic proteinase Source.85: DFBPPR2790 ---- Plant proteins ---- Auxin response factor 22 Source.86: DFBPPR2881 ---- Plant proteins ---- Probable protein NAP1 Source.87: DFBPPR3008 ---- Plant proteins ---- Potassium channel KOR1 Source.88: DFBPPR3123 ---- Plant proteins ---- Probable mitochondrial import receptor subunit TOM20 Source.89: DFBPPR3140 ---- Plant proteins ---- ABC transporter G family member 51 Source.90: DFBPPR3176 ---- Plant proteins ---- Cytochrome b6-f complex subunit 8 Source.91: DFBPPR3273 ---- Plant proteins ---- Dephospho-CoA kinase Source.92: DFBPPR3362 ---- Plant proteins ---- Probable alpha-glucosidase Os06g0675700 Source.93: DFBPPR3402 ---- Plant proteins ---- Probable auxin efflux carrier component 5c Source.94: DFBPPR3441 ---- Plant proteins ---- Chloroplastic group IIA intron splicing facilitator CRS1, chloroplastic Source.95: DFBPPR3579 ---- Plant proteins ---- Peptide methionine sulfoxide reductase A5 Source.96: DFBPPR3602 ---- Plant proteins ---- Coatomer subunit alpha-2 Source.97: DFBPPR3610 ---- Plant proteins ---- Auxin transporter-like protein 1 Source.98: DFBPPR3698 ---- Plant proteins ---- Sugar transport protein MST2 Source.99: DFBPPR3713 ---- Plant proteins ---- Probable NADH kinase Source.100: DFBPPR3822 ---- Plant proteins ---- Coatomer subunit alpha-3 Source.101: DFBPPR3855 ---- Plant proteins ---- Probable protein phosphatase 2C 66 Source.102: DFBPPR3910 ---- Plant proteins ---- Probable potassium transporter 3 Source.103: DFBPPR3926 ---- Plant proteins ---- Probable potassium transporter 13 Source.104: DFBPPR3928 ---- Plant proteins ---- Coatomer subunit alpha-1 Source.105: DFBPPR3993 ---- Plant proteins ---- Double-stranded RNA-binding protein 5 Source.106: DFBPPR4026 ---- Plant proteins ---- Potassium transporter 19 Source.107: DFBPPR4027 ---- Plant proteins ---- Potassium transporter 20 Source.108: DFBPPR4038 ---- Plant proteins ---- Probable metal-nicotianamine transporter YSL8 Source.109: DFBPPR4095 ---- Plant proteins ---- Probable anion transporter 4, chloroplastic Source.110: DFBPPR4142 ---- Plant proteins ---- Acylamino-acid-releasing enzyme 2 Source.111: DFBPPR4150 ---- Plant proteins ---- Probable potassium transporter 16 Source.112: DFBPPR4194 ---- Plant proteins ---- Potassium transporter 22 Source.113: DFBPPR4462 ---- Plant proteins ---- Ammonium transporter 2 member 3 Source.114: DFBPPR4549 ---- Plant proteins ---- Ammonium transporter 3 member 3 Source.115: DFBPPR4601 ---- Plant proteins ---- Probable Ufm1-specific protease Source.116: DFBPPR4628 ---- Plant proteins ---- Probable inactive carboxylesterase Os04g0669700 Source.117: DFBPPR4684 ---- Plant proteins ---- BURP domain-containing protein 17 Source.118: DFBPPR4732 ---- Plant proteins ---- BURP domain-containing protein 5 Source.119: DFBPPR4744 ---- Plant proteins ---- BURP domain-containing protein 3 Source.120: DFBPPR4787 ---- Plant proteins ---- 60S ribosomal protein L7a-1 Source.121: DFBPPR4823 ---- Plant proteins ---- 60S ribosomal protein L7a-2 Source.122: DFBPPR4889 ---- Plant proteins ---- Homeobox-leucine zipper protein ROC3 Source.123: DFBPPR4902 ---- Plant proteins ---- Endoribonuclease Dicer homolog 1 Source.124: DFBPPR4937 ---- Plant proteins ---- Glutamate synthase 2 [NADH], chloroplastic Source.125: DFBPPR4980 ---- Plant proteins ---- Lactoylglutathione lyase Source.126: DFBPPR5008 ---- Plant proteins ---- Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial Source.127: DFBPPR5011 ---- Plant proteins ---- Diacylglycerol O-acyltransferase 1A Source.128: DFBPPR5026 ---- Plant proteins ---- Phosphatidylinositol 3-kinase, root isoform Source.129: DFBPPR5027 ---- Plant proteins ---- Phosphatidylinositol 3-kinase, nodule isoform Source.130: DFBPPR5042 ---- Plant proteins ---- Diacylglycerol O-acyltransferase 1B Source.131: DFBPPR5044 ---- Plant proteins ---- Cytochrome c oxidase subunit 3 Source.132: DFBPPR5047 ---- Plant proteins ---- Photosystem I P700 chlorophyll a apoprotein A1 Source.133: DFBPPR5053 ---- Plant proteins ---- UDP-glucose 6-dehydrogenase 1 Source.134: DFBPPR5070 ---- Plant proteins ---- Phosphoribosylglycinamide formyltransferase, chloroplastic Source.135: DFBPPR5102 ---- Plant proteins ---- 4-hydroxy-tetrahydrodipicolinate synthase, chloroplastic Source.136: DFBPPR5219 ---- Plant proteins ---- Cytochrome b6-f complex subunit 8 Source.137: DFBPPR5326 ---- Plant proteins ---- Cytochrome P450 77A3 Source.138: DFBPPR5563 ---- Plant proteins ---- Photosystem I P700 chlorophyll a apoprotein A1 Source.139: DFBPPR5565 ---- Plant proteins ---- Chloroplastic group IIA intron splicing facilitator CRS1, chloroplastic Source.140: DFBPPR5651 ---- Plant proteins ---- Cytochrome c Source.141: DFBPPR5881 ---- Plant proteins ---- Divinyl chlorophyllide a 8-vinyl-reductase, chloroplastic Source.142: DFBPPR5921 ---- Plant proteins ---- Cytochrome b6-f complex subunit 8 Source.143: DFBPPR5933 ---- Plant proteins ---- Pathogenesis-related protein PRMS Source.144: DFBPPR6008 ---- Plant proteins ---- Zein-beta Source.145: DFBPPR6274 ---- Plant proteins ---- Photosystem I P700 chlorophyll a apoprotein A1 Source.146: DFBPPR6350 ---- Plant proteins ---- Galactoside 2-alpha-L-fucosyltransferase Source.147: DFBPPR6388 ---- Plant proteins ---- Aldehyde dehydrogenase family 7 member A1 Source.148: DFBPPR6696 ---- Plant proteins ---- Photosystem I P700 chlorophyll a apoprotein A1 Source.149: DFBPPR6775 ---- Plant proteins ---- NADH-ubiquinone oxidoreductase chain 4 Source.150: DFBPPR6778 ---- Plant proteins ---- Cytochrome c oxidase subunit 3 Source.151: DFBPPR6864 ---- Plant proteins ---- Cytochrome b6-f complex subunit 8 Source.152: DFBPPR7015 ---- Plant proteins ---- Phytepsin Source.153: DFBPPR7065 ---- Plant proteins ---- Photosystem I P700 chlorophyll a apoprotein A1 Source.154: DFBPPR7158 ---- Plant proteins ---- Nucleotide pyrophosphatase/phosphodiesterase Source.155: DFBPPR7199 ---- Plant proteins ---- Pathogenesis-related protein PRB1-3 Source.156: DFBPPR7238 ---- Plant proteins ---- Pathogenesis-related protein 1 Source.157: DFBPPR7239 ---- Plant proteins ---- Pathogenesis-related protein PRB1-2 Source.158: DFBPPR7245 ---- Plant proteins ---- Cytochrome b6-f complex subunit 8 Source.159: DFBPPR7450 ---- Plant proteins ---- Aldehyde dehydrogenase family 7 member A1 Source.160: DFBPPR7596 ---- Milk proteins ---- Lactotransferrin Source.161: DFBPPR7641 ---- Milk proteins ---- Lactase-phlorizin hydrolase Source.162: DFBPPR7655 ---- Milk proteins ---- Protein FAM13A Source.163: DFBPPR7658 ---- Milk proteins ---- Lactotransferrin Source.164: DFBPPR7669 ---- Milk proteins ---- Lactotransferrin Source.165: DFBPPR7683 ---- Milk proteins ---- Lactotransferrin Source.166: DFBPPR7713 ---- Milk proteins ---- Lactotransferrin Source.167: DFBPPR8432 ---- Plant proteins ---- Omega-3 fatty acid desaturase, chloroplastic Source.168: DFBPPR8500 ---- Milk proteins ---- Lactotransferrin Source.169: DFBPPR15960 ---- Animal proteins ---- Apolipoprotein A-IV Source.170: DFBPPR15979 ---- Animal proteins ---- Serine/threonine-protein kinase NLK Source.171: DFBPPR15985 ---- Animal proteins ---- von Willebrand factor Source.172: DFBPPR16023 ---- Animal proteins ---- Platelet-derived growth factor receptor beta Source.173: DFBPPR16052 ---- Animal proteins ---- Atypical chemokine receptor 3 Source.174: DFBPPR16097 ---- Animal proteins ---- Thyrotropin receptor Source.175: DFBPPR16107 ---- Animal proteins ---- NAD-dependent protein deacylase sirtuin-5, mitochondrial Source.176: DFBPPR16136 ---- Animal proteins ---- C-X-C chemokine receptor type 3 Source.177: DFBPPR16184 ---- Animal proteins ---- C5a anaphylatoxin chemotactic receptor 1 Source.178: DFBPPR16221 ---- Animal proteins ---- Xylosyltransferase 2 Source.179: DFBPPR16310 ---- Animal proteins ---- Zinc-activated ligand-gated ion channel Source.180: DFBPPR16335 ---- Animal proteins ---- Sodium channel subunit beta-1 Source.181: DFBPPR16509 ---- Animal proteins ---- Substance-K receptor Source.182: DFBPPR16540 ---- Animal proteins ---- Desmoglein-3 Source.183: DFBPPR16594 ---- Animal proteins ---- Macoilin Source.184: DFBPPR16617 ---- Animal proteins ---- Beta-crystallin A4 Source.185: DFBPPR16778 ---- Animal proteins ---- Prolactin receptor Source.186: DFBPPR16831 ---- Animal proteins ---- Fibrinogen beta chain Source.187: DFBPPR16839 ---- Animal proteins ---- Myelin proteolipid protein Source.188: DFBPPR16878 ---- Animal proteins ---- Prostacyclin synthase Source.189: DFBPPR16929 ---- Animal proteins ---- N-acetyllactosaminide alpha-1,3-galactosyltransferase Source.190: DFBPPR16986 ---- Animal proteins ---- Aspartyl/asparaginyl beta-hydroxylase Source.191: DFBPPR17004 ---- Animal proteins ---- NAD-dependent protein deacylase sirtuin-5, mitochondrial Source.192: DFBPPR17018 ---- Animal proteins ---- Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 Source.193: DFBPPR17024 ---- Animal proteins ---- Sodium-dependent serotonin transporter Source.194: DFBPPR17072 ---- Animal proteins ---- Myosin light chain kinase, smooth muscle Source.195: DFBPPR17085 ---- Animal proteins ---- Cadherin-2 Source.196: DFBPPR17117 ---- Animal proteins ---- Beta-hexosaminidase subunit alpha Source.197: DFBPPR17204 ---- Animal proteins ---- Platelet-activating factor acetylhydrolase IB subunit alpha2 Source.198: DFBPPR17232 ---- Animal proteins ---- Angiopoietin-1 receptor Source.199: DFBPPR17233 ---- Animal proteins ---- Angiopoietin-1 receptor Source.200: DFBPPR17406 ---- Animal proteins ---- Exostosin-2 Source.201: DFBPPR17480 ---- Animal proteins ---- Platelet-activating factor acetylhydrolase IB subunit alpha1 Source.202: DFBPPR17595 ---- Animal proteins ---- Cytochrome c oxidase subunit 3 Source.203: DFBPPR17644 ---- Animal proteins ---- CCAAT/enhancer-binding protein beta Source.204: DFBPPR17825 ---- Animal proteins ---- Thyrotropin receptor Source.205: DFBPPR17847 ---- Animal proteins ---- Palmitoyltransferase ZDHHC20 Source.206: DFBPPR17924 ---- Animal proteins ---- Sodium-dependent dopamine transporter Source.207: DFBPPR17975 ---- Animal proteins ---- Peroxisomal N(1)-acetyl-spermine/spermidine oxidase Source.208: DFBPPR17979 ---- Animal proteins ---- Sodium channel subunit beta-1 Source.209: DFBPPR18012 ---- Animal proteins ---- Neural cell adhesion molecule 1 Source.210: DFBPPR18055 ---- Animal proteins ---- E3 ubiquitin-protein ligase MARCHF8 Source.211: DFBPPR18116 ---- Animal proteins ---- Carbonic anhydrase 4 Source.212: DFBPPR18135 ---- Animal proteins ---- Dihydrofolate reductase Source.213: DFBPPR18209 ---- Animal proteins ---- Sodium-dependent noradrenaline transporter Source.214: DFBPPR18222 ---- Animal proteins ---- Xylosyltransferase 2 Source.215: DFBPPR18320 ---- Animal proteins ---- Serine/threonine-protein kinase NLK Source.216: DFBPPR18440 ---- Animal proteins ---- Protein 4.2 Source.217: DFBPPR18444 ---- Animal proteins ---- Beta-1 adrenergic receptor Source.218: DFBPPR18580 ---- Animal proteins ---- GLIPR1-like protein 1 Source.219: DFBPPR18588 ---- Animal proteins ---- CD166 antigen Source.220: DFBPPR18812 ---- Animal proteins ---- Vesicle-associated membrane protein 3 Source.221: DFBPPR18819 ---- Animal proteins ---- Proteasome activator complex subunit 4 Source.222: DFBPPR18822 ---- Animal proteins ---- Sterol regulatory element-binding protein cleavage-activating protein Source.223: DFBPPR18840 ---- Animal proteins ---- NEDD8-conjugating enzyme UBE2F Source.224: DFBPPR18878 ---- Animal proteins ---- Acylamino-acid-releasing enzyme Source.225: DFBPPR18949 ---- Animal proteins ---- Ubiquitin carboxyl-terminal hydrolase MINDY-2 Source.226: DFBPPR18963 ---- Animal proteins ---- F-box/WD repeat-containing protein 7 Source.227: DFBPPR19207 ---- Animal proteins ---- Putative sodium-coupled neutral amino acid transporter 7 Source.228: DFBPPR19230 ---- Animal proteins ---- Interferon alpha-G Source.229: DFBPPR19329 ---- Animal proteins ---- CD302 antigen Source.230: DFBPPR19414 ---- Animal proteins ---- Exocyst complex component 8 Source.231: DFBPPR19475 ---- Animal proteins ---- Coronin-7 Source.232: DFBPPR19504 ---- Animal proteins ---- Cytosolic Fe-S cluster assembly factor NUBP2 Source.233: DFBPPR19527 ---- Animal proteins ---- Protein phosphatase 1 regulatory subunit 15A Source.234: DFBPPR19584 ---- Animal proteins ---- Xaa-Pro aminopeptidase 1 Source.235: DFBPPR19604 ---- Animal proteins ---- Protein-lysine methyltransferase METTL21C Source.236: DFBPPR19630 ---- Animal proteins ---- Glycerol kinase Source.237: DFBPPR19691 ---- Animal proteins ---- Ubiquitin carboxyl-terminal hydrolase MINDY-1 Source.238: DFBPPR19721 ---- Animal proteins ---- G-protein coupled receptor 4 Source.239: DFBPPR19901 ---- Animal proteins ---- Aspartate--tRNA ligase, cytoplasmic Source.240: DFBPPR19982 ---- Animal proteins ---- 3'(2'),5'-bisphosphate nucleotidase 1 Source.241: DFBPPR20017 ---- Animal proteins ---- Lysoplasmalogenase Source.242: DFBPPR20042 ---- Animal proteins ---- Neuroendocrine convertase 1 Source.243: DFBPPR20287 ---- Animal proteins ---- Large neutral amino acids transporter small subunit 4 Source.244: DFBPPR20322 ---- Animal proteins ---- GTPase Era, mitochondrial Source.245: DFBPPR20329 ---- Animal proteins ---- Meiosis regulator and mRNA stability factor 1 Source.246: DFBPPR20478 ---- Animal proteins ---- Macoilin Source.247: DFBPPR20507 ---- Animal proteins ---- G protein-coupled receptor 161 Source.248: DFBPPR20543 ---- Animal proteins ---- Procollagen galactosyltransferase 1 Source.249: DFBPPR20599 ---- Animal proteins ---- Cleavage and polyadenylation specificity factor subunit 1 Source.250: DFBPPR20653 ---- Animal proteins ---- Carboxylesterase 4A Source.251: DFBPPR20658 ---- Animal proteins ---- G-protein coupled receptor family C group 5 member C Source.252: DFBPPR20662 ---- Animal proteins ---- C4b-binding protein alpha chain Source.253: DFBPPR20777 ---- Animal proteins ---- Sodium-coupled monocarboxylate transporter 2 Source.254: DFBPPR20801 ---- Animal proteins ---- Probable G-protein coupled receptor 171 Source.255: DFBPPR20932 ---- Animal proteins ---- Ig-like V-type domain-containing protein FAM187A Source.256: DFBPPR20951 ---- Animal proteins ---- Chitinase domain-containing protein 1 Source.257: DFBPPR20999 ---- Animal proteins ---- Protein SERAC1 Source.258: DFBPPR21026 ---- Animal proteins ---- Fetal and adult testis-expressed transcript protein homolog Source.259: DFBPPR21059 ---- Animal proteins ---- V-set and immunoglobulin domain-containing protein 1 Source.260: DFBPPR21102 ---- Animal proteins ---- Gamma-glutamylcyclotransferase Source.261: DFBPPR21113 ---- Animal proteins ---- Peptidase inhibitor 16 Source.262: DFBPPR21164 ---- Animal proteins ---- Probable cytosolic iron-sulfur protein assembly protein CIAO1 Source.263: DFBPPR21196 ---- Animal proteins ---- Beta-crystallin A4 Source.264: DFBPPR21202 ---- Animal proteins ---- Leukotriene B4 receptor 1 Source.265: DFBPPR21311 ---- Animal proteins ---- WD repeat-containing protein 18 Source.266: DFBPPR21360 ---- Animal proteins ---- Transmembrane protein 158 Source.267: DFBPPR21387 ---- Animal proteins ---- Surfeit locus protein 4 Source.268: DFBPPR21426 ---- Animal proteins ---- ORM1-like protein 3 Source.269: DFBPPR21448 ---- Animal proteins ---- Protein N-lysine methyltransferase METTL21A Source.270: DFBPPR21482 ---- Animal proteins ---- Glycosyltransferase 6 domain-containing protein 1 Source.271: DFBPPR21568 ---- Animal proteins ---- FAST kinase domain-containing protein 4 Source.272: DFBPPR21612 ---- Animal proteins ---- Probable inactive glycosyltransferase 25 family member 3 Source.273: DFBPPR21613 ---- Animal proteins ---- Probable inactive glycosyltransferase 25 family member 3 Source.274: DFBPPR21739 ---- Animal proteins ---- Sorting nexin-15 Source.275: DFBPPR21808 ---- Animal proteins ---- Solute carrier family 22 member 7 Source.276: DFBPPR21815 ---- Animal proteins ---- ORM1-like protein 2 Source.277: DFBPPR21849 ---- Animal proteins ---- ALS2 C-terminal-like protein Source.278: DFBPPR21939 ---- Animal proteins ---- Inter-alpha-trypsin inhibitor heavy chain H5 Source.279: DFBPPR22010 ---- Animal proteins ---- Protein-lysine methyltransferase METTL21E Source.280: DFBPPR22014 ---- Animal proteins ---- Solute carrier family 43 member 3 Source.281: DFBPPR22047 ---- Animal proteins ---- WD repeat-containing protein 6 Source.282: DFBPPR22068 ---- Animal proteins ---- Protein GPR108 Source.283: DFBPPR22186 ---- Animal proteins ---- Transmembrane and ubiquitin-like domain-containing protein 2 Source.284: DFBPPR22240 ---- Animal proteins ---- Ataxin-10 Source.285: DFBPPR22397 ---- Animal proteins ---- NHL repeat-containing protein 2 Source.286: DFBPPR22418 ---- Animal proteins ---- Transmembrane protein 160 Source.287: DFBPPR22517 ---- Animal proteins ---- F-box only protein 15 Source.288: DFBPPR22595 ---- Animal proteins ---- Transmembrane protein 268 Source.289: DFBPPR22606 ---- Animal proteins ---- WD repeat-containing protein 53 Source.290: DFBPPR22748 ---- Animal proteins ---- Uncharacterized protein C5orf34 homolog Source.291: DFBPPR8534 ---- Animal proteins ---- Zona pellucida sperm-binding protein 4 Source.292: DFBPPR8583 ---- Animal proteins ---- Amiloride-sensitive amine oxidase [copper-containing] Source.293: DFBPPR8649 ---- Animal proteins ---- Acrosin Source.294: DFBPPR8711 ---- Animal proteins ---- Fumarate hydratase, mitochondrial Source.295: DFBPPR8916 ---- Animal proteins ---- Glutaryl-CoA dehydrogenase, mitochondrial Source.296: DFBPPR8954 ---- Animal proteins ---- N-acetyllactosaminide alpha-1,3-galactosyltransferase Source.297: DFBPPR8978 ---- Animal proteins ---- Inter-alpha-trypsin inhibitor heavy chain H4 Source.298: DFBPPR8983 ---- Animal proteins ---- Receptor activity-modifying protein 1 Source.299: DFBPPR9008 ---- Animal proteins ---- Sterol regulatory element-binding protein cleavage-activating protein Source.300: DFBPPR9061 ---- Animal proteins ---- Caspase-1 Source.301: DFBPPR9103 ---- Animal proteins ---- Beta-1 adrenergic receptor Source.302: DFBPPR9132 ---- Animal proteins ---- Dystrophin Source.303: DFBPPR9202 ---- Animal proteins ---- 5-hydroxytryptamine receptor 2B Source.304: DFBPPR9269 ---- Animal proteins ---- Cytochrome c oxidase subunit 3 Source.305: DFBPPR9330 ---- Animal proteins ---- Receptor activity-modifying protein 3 Source.306: DFBPPR9484 ---- Animal proteins ---- Macoilin Source.307: DFBPPR9565 ---- Animal proteins ---- Melanoma-associated antigen D1 Source.308: DFBPPR9569 ---- Animal proteins ---- Myelin proteolipid protein Source.309: DFBPPR9689 ---- Animal proteins ---- G-protein coupled receptor 4 Source.310: DFBPPR9703 ---- Animal proteins ---- Membrane-associated transporter protein Source.311: DFBPPR9727 ---- Animal proteins ---- FAST kinase domain-containing protein 4 Source.312: DFBPPR9843 ---- Animal proteins ---- P protein Source.313: DFBPPR9873 ---- Animal proteins ---- Solute carrier family 22 member 7 Source.314: DFBPPR9983 ---- Animal proteins ---- Fibrinogen alpha chain Source.315: DFBPPR9995 ---- Animal proteins ---- Melanocyte protein PMEL Source.316: DFBPPR10076 ---- Animal proteins ---- Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 Source.317: DFBPPR10106 ---- Animal proteins ---- Glycerol-3-phosphate acyltransferase 3 Source.318: DFBPPR10116 ---- Animal proteins ---- Cadherin-2 Source.319: DFBPPR10147 ---- Animal proteins ---- Proto-oncogene tyrosine-protein kinase ROS Source.320: DFBPPR10149 ---- Animal proteins ---- Calpain-2 catalytic subunit Source.321: DFBPPR10236 ---- Animal proteins ---- Acid-sensing ion channel 1 Source.322: DFBPPR10295 ---- Animal proteins ---- NAD-dependent protein deacylase sirtuin-5, mitochondrial Source.323: DFBPPR10314 ---- Animal proteins ---- Angiotensin-converting enzyme Source.324: DFBPPR10351 ---- Animal proteins ---- Protein sidekick-2 Source.325: DFBPPR10397 ---- Animal proteins ---- Tyrosine-protein kinase receptor TYRO3 Source.326: DFBPPR10458 ---- Animal proteins ---- Neurofascin Source.327: DFBPPR10512 ---- Animal proteins ---- Collagen alpha-1(XIV) chain Source.328: DFBPPR10630 ---- Animal proteins ---- Contactin-2 Source.329: DFBPPR10641 ---- Animal proteins ---- Signal peptide peptidase-like 2B Source.330: DFBPPR10800 ---- Animal proteins ---- DNA polymerase subunit gamma-1 Source.331: DFBPPR10869 ---- Animal proteins ---- Ribosomal oxygenase 1 Source.332: DFBPPR10946 ---- Animal proteins ---- Corticotropin-releasing factor receptor 1 Source.333: DFBPPR10947 ---- Animal proteins ---- Cytosolic carboxypeptidase 1 Source.334: DFBPPR10964 ---- Animal proteins ---- Protein artemis Source.335: DFBPPR11014 ---- Animal proteins ---- NEDD8-conjugating enzyme UBE2F Source.336: DFBPPR11019 ---- Animal proteins ---- Cadherin-4 Source.337: DFBPPR11109 ---- Animal proteins ---- Fibrinogen-like protein 1-like protein Source.338: DFBPPR11152 ---- Animal proteins ---- Platelet-activating factor acetylhydrolase IB subunit alpha2 Source.339: DFBPPR11166 ---- Animal proteins ---- Phosphatidylinositol 4-kinase type 2-beta Source.340: DFBPPR11196 ---- Animal proteins ---- Mitochondrial Rho GTPase 2 Source.341: DFBPPR11221 ---- Animal proteins ---- Zinc finger homeobox protein 4 Source.342: DFBPPR11271 ---- Animal proteins ---- Protection of telomeres protein 1 Source.343: DFBPPR11376 ---- Animal proteins ---- Lamin-A Source.344: DFBPPR11539 ---- Animal proteins ---- Cytosolic Fe-S cluster assembly factor NUBP2 Source.345: DFBPPR11619 ---- Animal proteins ---- Exocyst complex component 8 Source.346: DFBPPR11654 ---- Animal proteins ---- NADH-ubiquinone oxidoreductase chain 6 Source.347: DFBPPR11691 ---- Animal proteins ---- Beta-crystallin A4 Source.348: DFBPPR11707 ---- Animal proteins ---- Nuclear cap-binding protein subunit 3 Source.349: DFBPPR11721 ---- Animal proteins ---- Eukaryotic translation initiation factor 2A Source.350: DFBPPR11764 ---- Animal proteins ---- Tectonin beta-propeller repeat-containing protein 1 Source.351: DFBPPR11817 ---- Animal proteins ---- Meiosis regulator and mRNA stability factor 1 Source.352: DFBPPR11855 ---- Animal proteins ---- G-protein coupled receptor-associated protein LMBRD2 Source.353: DFBPPR11933 ---- Animal proteins ---- M-protein, striated muscle Source.354: DFBPPR11978 ---- Animal proteins ---- ER membrane protein complex subunit 1 Source.355: DFBPPR12016 ---- Animal proteins ---- ORM1-like protein 2 Source.356: DFBPPR12117 ---- Animal proteins ---- Cysteine-rich secretory protein LCCL domain-containing 1 Source.357: DFBPPR12243 ---- Animal proteins ---- Glycosyltransferase-like domain-containing protein 1 Source.358: DFBPPR12272 ---- Animal proteins ---- Large neutral amino acids transporter small subunit 1 Source.359: DFBPPR12321 ---- Animal proteins ---- Voltage-dependent N-type calcium channel subunit alpha-1B Source.360: DFBPPR12355 ---- Animal proteins ---- Glucose-6-phosphate isomerase Source.361: DFBPPR12377 ---- Animal proteins ---- Myosin light chain kinase, smooth muscle Source.362: DFBPPR12422 ---- Animal proteins ---- Voltage-dependent R-type calcium channel subunit alpha-1E Source.363: DFBPPR12453 ---- Animal proteins ---- Lactase-phlorizin hydrolase Source.364: DFBPPR12512 ---- Animal proteins ---- Carbonic anhydrase 4 Source.365: DFBPPR12548 ---- Animal proteins ---- C5a anaphylatoxin chemotactic receptor 1 Source.366: DFBPPR12570 ---- Animal proteins ---- 5-hydroxytryptamine receptor 1D Source.367: DFBPPR12595 ---- Animal proteins ---- Hyaluronidase PH-20 Source.368: DFBPPR12722 ---- Animal proteins ---- Myelin proteolipid protein Source.369: DFBPPR12771 ---- Animal proteins ---- Sodium channel subunit beta-1 Source.370: DFBPPR12774 ---- Animal proteins ---- Arginase-2, mitochondrial Source.371: DFBPPR12838 ---- Animal proteins ---- Cytochrome c oxidase subunit 3 Source.372: DFBPPR13072 ---- Animal proteins ---- Solute carrier family 22 member 7 Source.373: DFBPPR13223 ---- Animal proteins ---- Caspase-1 Source.374: DFBPPR13304 ---- Animal proteins ---- Cytochrome c oxidase subunit 3 Source.375: DFBPPR13349 ---- Animal proteins ---- Cysteine-rich secretory protein 3 Source.376: DFBPPR13608 ---- Animal proteins ---- Myosin light chain kinase, smooth muscle Source.377: DFBPPR13612 ---- Animal proteins ---- Thyrotropin receptor Source.378: DFBPPR13629 ---- Animal proteins ---- Copper-transporting ATPase 2 Source.379: DFBPPR13675 ---- Animal proteins ---- Cytochrome c oxidase subunit 3 Source.380: DFBPPR13684 ---- Animal proteins ---- Beta-1 adrenergic receptor Source.381: DFBPPR14015 ---- Animal proteins ---- Cytochrome c oxidase subunit 3 Source.382: DFBPPR14119 ---- Marine protein ---- Cytochrome c oxidase subunit 3 Source.383: DFBPPR14171 ---- Marine protein ---- Golgi pH regulator Source.384: DFBPPR14201 ---- Marine protein ---- Probable cytosolic iron-sulfur protein assembly protein ciao1-B Source.385: DFBPPR14203 ---- Marine protein ---- Probable cytosolic iron-sulfur protein assembly protein ciao1-A Source.386: DFBPPR14257 ---- Marine protein ---- Somatolactin Source.387: DFBPPR14267 ---- Marine protein ---- Cytochrome c oxidase subunit 4 isoform 2, mitochondrial Source.388: DFBPPR14290 ---- Marine protein ---- Ribulose bisphosphate carboxylase large chain Source.389: DFBPPR14312 ---- Marine protein ---- Cytochrome c biogenesis protein CcsA Source.390: DFBPPR14331 ---- Marine protein ---- Photosystem I P700 chlorophyll a apoprotein A1 Source.391: DFBPPR14332 ---- Marine protein ---- Ribulose bisphosphate carboxylase large chain Source.392: DFBPPR14384 ---- Marine protein ---- Cytochrome b6-f complex subunit 8 Source.393: DFBPPR14452 ---- Marine protein ---- Cytochrome c biogenesis protein CcsA Source.394: DFBPPR14567 ---- Marine protein ---- C5a anaphylatoxin chemotactic receptor 1 Source.395: DFBPPR14627 ---- Marine protein ---- Cytochrome c oxidase subunit 3 Source.396: DFBPPR14974 ---- Microorganism protein ---- Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit Source.397: DFBPPR15078 ---- Microorganism protein ---- Autophagy-related protein 11 Source.398: DFBPPR15160 ---- Microorganism protein ---- Palmitoyltransferase PFA3 Source.399: DFBPPR15352 ---- Microorganism protein ---- Cytosolic Fe-S cluster assembly factor CFD1 Source.400: DFBPPR15371 ---- Microorganism protein ---- Protein HIR2 Source.401: DFBPPR15438 ---- Microorganism protein ---- 3-keto-steroid reductase Source.402: DFBPPR15580 ---- Microorganism protein ---- Oligosaccharide translocation protein RFT1 Source.403: DFBPPR15605 ---- Microorganism protein ---- Ribosome biogenesis protein NSA2 Source.404: DFBPPR15770 ---- Microorganism protein ---- F-box protein COS111 Source.405: DFBPPR15866 ---- Microorganism protein ---- Delta-1-pyrroline-5-carboxylate dehydrogenase Source.406: DFBPPR15870 ---- Microorganism protein ---- Glucose-6-phosphate isomerase Source.407: DFBPPR0001 ---- Plant protein ---- Gamma conglutin 1 Source.408: DFBPPR7772 ---- Plant protein ---- Photosystem I P700 chlorophyll a apoprotein A1 Source.409: DFBPPR7833 ---- Plant protein ---- Cytochrome b6-f complex subunit 8 Source.410: DFBPPR7916 ---- Plant protein ---- CASP-like protein 1U3 Source.411: DFBPPR7992 ---- Plant protein ---- Photosystem I P700 chlorophyll a apoprotein A1 Source.412: DFBPPR8007 ---- Plant protein ---- Maturase K Source.413: DFBPPR8035 ---- Plant protein ---- Endochitinase Source.414: DFBPPR8044 ---- Plant protein ---- Photosystem I P700 chlorophyll a apoprotein A1 Source.415: DFBPPR8058 ---- Plant protein ---- Endochitinase CH5B Source.416: DFBPPR8112 ---- Plant protein ---- Cytochrome b6-f complex subunit 8 Source.417: DFBPPR8224 ---- Plant protein ---- Photosystem I P700 chlorophyll a apoprotein A1 Source.418: DFBPPR8278 ---- Plant protein ---- Cytochrome b6-f complex subunit 8
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

ACE-inhibitory activity	The peptide exhibited potent Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) inhibitory activity with an IC₅₀ value of 76.7 ± 10.1 μM.
Specific target protein(s)	Specific Target Protein(s): Angiotensin-converting enzyme

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Bitter taste ^prediction

SMILES

N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)O

Preparation method

Mode of preparation	Enzymatic hydrolysis
Enzyme(s)/starter culture	The ACE inhibitory peptide was in silico screened from the product generated by virtual gastrointestinal digestion of the proteins from C. vulgaris.

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Xie J, Chen X, Wu J, Zhang Y, Zhou Y, Zhang L, Tang YJ, Wei D. Antihypertensive Effects, Molecular Docking Study, and Isothermal Titration Calorimetry Assay of Angiotensin I-Converting Enzyme Inhibitory Peptides from Chlorella vulgaris. J Agric Food Chem. 2018 Feb 14;66(6):1359-1368. PMID: 29345929 DOI: 10.1021/acs.jafc.7b04294
Other literature(s)	N.D
PubDate	2018