Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPACEI2057(ACE-inhibitory peptide)

DFBP ID	DFBPACEI2057
Peptide sequence	EYC
Type	Native peptide
Peptide/Function name	ACE-inhibitory peptide

Function-activity relationship

Main bioactivity	ACE-inhibitory activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

Glu-Tyr-Cys

Single-letter amino acid

EYC

Peptide length

Peptide mass

Experimental mass	Theoretical mass
413.45 Da	413.45 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

3.34 ^c

IC₅₀

217.58 ± 6.47 μM

pIC₅₀

-2.338

GRAVY

-0.7667^c

Hydrophilic residue ratio

0%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Animal
Organism/Source	Korat-chicken
Precursor protein	Myosin
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR0387 ---- Plant protein ---- Alpha purothionin Source.2: DFBPPR0959 ---- Plant proteins ---- Probable serine/threonine-protein kinase BSK3 Source.3: DFBPPR1067 ---- Plant proteins ---- Serine/threonine protein kinase OSK4 Source.4: DFBPPR1257 ---- Plant proteins ---- Transcription factor MYB2 Source.5: DFBPPR1300 ---- Plant proteins ---- Protein G1 Source.6: DFBPPR1315 ---- Plant proteins ---- Gibberellin 20 oxidase 3 Source.7: DFBPPR1354 ---- Plant proteins ---- Brassinosteroid LRR receptor kinase BRL3 Source.8: DFBPPR1536 ---- Plant proteins ---- Protein DWARF 53 Source.9: DFBPPR1560 ---- Plant proteins ---- Serine/threonine protein kinase OSK3 Source.10: DFBPPR1620 ---- Plant proteins ---- MADS-box transcription factor 29 Source.11: DFBPPR1916 ---- Plant proteins ---- Protein PYRICULARIA ORYZAE RESISTANCE 21 Source.12: DFBPPR1959 ---- Plant proteins ---- DNA gyrase subunit B, chloroplastic/mitochondrial Source.13: DFBPPR2064 ---- Plant proteins ---- Linoleate 9S-lipoxygenase 1 Source.14: DFBPPR2083 ---- Plant proteins ---- Lectin Source.15: DFBPPR2098 ---- Plant proteins ---- DNA replication licensing factor MCM5 Source.16: DFBPPR2147 ---- Plant proteins ---- Two-component response regulator ORR23 Source.17: DFBPPR2159 ---- Plant proteins ---- NAD(P)H-quinone oxidoreductase subunit I, chloroplastic Source.18: DFBPPR2373 ---- Plant proteins ---- Adagio-like protein 3 Source.19: DFBPPR2472 ---- Plant proteins ---- Heat stress transcription factor B-4d Source.20: DFBPPR2485 ---- Plant proteins ---- SKP1-like protein 1 Source.21: DFBPPR2627 ---- Plant proteins ---- Long chain base biosynthesis protein 2a Source.22: DFBPPR2648 ---- Plant proteins ---- SKP1-like protein 20 Source.23: DFBPPR2683 ---- Plant proteins ---- Exonuclease 1 Source.24: DFBPPR2690 ---- Plant proteins ---- E3 ubiquitin-protein ligase makorin Source.25: DFBPPR2709 ---- Plant proteins ---- Long chain base biosynthesis protein 2b Source.26: DFBPPR2755 ---- Plant proteins ---- Adenylate kinase 4 Source.27: DFBPPR2778 ---- Plant proteins ---- PHD finger protein PERSISTENT TAPETAL CELL 1 Source.28: DFBPPR2810 ---- Plant proteins ---- Probable N6-adenosine-methyltransferase MT-A70-like Source.29: DFBPPR2832 ---- Plant proteins ---- Probable histone acetyltransferase HAC-like 1 Source.30: DFBPPR2868 ---- Plant proteins ---- Probable 4-coumarate--CoA ligase 2 Source.31: DFBPPR2982 ---- Plant proteins ---- SKP1-like protein 5 Source.32: DFBPPR3019 ---- Plant proteins ---- Long chain base biosynthesis protein 2c Source.33: DFBPPR3202 ---- Plant proteins ---- Probable 4-coumarate--CoA ligase 3 Source.34: DFBPPR3211 ---- Plant proteins ---- Exocyst complex component 5 Source.35: DFBPPR3425 ---- Plant proteins ---- Transcription initiation factor TFIID subunit 1 Source.36: DFBPPR3583 ---- Plant proteins ---- TATA box-binding protein-associated factor RNA polymerase I subunit B Source.37: DFBPPR3623 ---- Plant proteins ---- Kinesin-like protein KIN-14K Source.38: DFBPPR3706 ---- Plant proteins ---- 17kDa alpha-amylase/trypsin inhibitor 2 Source.39: DFBPPR3711 ---- Plant proteins ---- 17kDa alpha-amylase/trypsin inhibitor 1 Source.40: DFBPPR3858 ---- Plant proteins ---- Putative protein phosphatase 2C 46 Source.41: DFBPPR4011 ---- Plant proteins ---- Sugar transport protein MST1 Source.42: DFBPPR4240 ---- Plant proteins ---- Protein DWARF 53-LIKE Source.43: DFBPPR4397 ---- Plant proteins ---- Two-component response regulator ORR31 Source.44: DFBPPR4404 ---- Plant proteins ---- Two-component response regulator ORR32 Source.45: DFBPPR4652 ---- Plant proteins ---- Probable protein ABIL1 Source.46: DFBPPR4692 ---- Plant proteins ---- Probable protein ABIL4 Source.47: DFBPPR4914 ---- Plant proteins ---- Serine/threonine-protein kinase BSK1-2 Source.48: DFBPPR4919 ---- Plant proteins ---- Serine/threonine protein kinase OSK1 Source.49: DFBPPR4948 ---- Plant proteins ---- Long chain base biosynthesis protein 2d Source.50: DFBPPR5021 ---- Plant proteins ---- Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic Source.51: DFBPPR5072 ---- Plant proteins ---- Cell division cycle protein 48 homolog Source.52: DFBPPR5122 ---- Plant proteins ---- NAD(P)H-quinone oxidoreductase subunit I, chloroplastic Source.53: DFBPPR5642 ---- Plant proteins ---- Zeamatin Source.54: DFBPPR5670 ---- Plant proteins ---- Endochitinase B Source.55: DFBPPR5741 ---- Plant proteins ---- NAD(P)H-quinone oxidoreductase subunit I, chloroplastic Source.56: DFBPPR5766 ---- Plant proteins ---- MADS-box protein ZMM17 Source.57: DFBPPR5988 ---- Plant proteins ---- Alpha-amylase/trypsin inhibitor Source.58: DFBPPR6286 ---- Plant proteins ---- Endochitinase A2 Source.59: DFBPPR6655 ---- Plant proteins ---- Agglutinin isolectin 1 Source.60: DFBPPR6657 ---- Plant proteins ---- Agglutinin isolectin 2 Source.61: DFBPPR6661 ---- Plant proteins ---- Agglutinin isolectin 3 Source.62: DFBPPR6723 ---- Plant proteins ---- Ubiquitin-conjugating enzyme E2-23 kDa Source.63: DFBPPR6733 ---- Plant proteins ---- NAD(P)H-quinone oxidoreductase subunit I, chloroplastic Source.64: DFBPPR6742 ---- Plant proteins ---- Alpha-1-purothionin Source.65: DFBPPR6745 ---- Plant proteins ---- Purothionin A-1 Source.66: DFBPPR6868 ---- Plant proteins ---- Alpha-2-purothionin Source.67: DFBPPR6879 ---- Plant proteins ---- Type-5 thionin Source.68: DFBPPR7133 ---- Plant proteins ---- NAD(P)H-quinone oxidoreductase subunit I, chloroplastic Source.69: DFBPPR7184 ---- Plant proteins ---- Root-specific lectin Source.70: DFBPPR7202 ---- Plant proteins ---- UTP--glucose-1-phosphate uridylyltransferase Source.71: DFBPPR7246 ---- Plant proteins ---- Leaf-specific thionin Source.72: DFBPPR7267 ---- Plant proteins ---- Thionin BTH7 Source.73: DFBPPR7268 ---- Plant proteins ---- Probable leaf thionin Source.74: DFBPPR7420 ---- Plant proteins ---- Polygalacturonase Source.75: DFBPPR7496 ---- Plant proteins ---- AP2-like ethylene-responsive transcription factor BBM1 Source.76: DFBPPR7497 ---- Plant proteins ---- AP2-like ethylene-responsive transcription factor BBM2 Source.77: DFBPPR7601 ---- Milk proteins ---- Lactoperoxidase Source.78: DFBPPR7616 ---- Milk proteins ---- Macrophage mannose receptor 1 Source.79: DFBPPR7618 ---- Milk proteins ---- Plasminogen Source.80: DFBPPR7638 ---- Milk proteins ---- Tissue-type plasminogen activator Source.81: DFBPPR7651 ---- Milk proteins ---- Macrophage colony-stimulating factor 1 receptor Source.82: DFBPPR7682 ---- Milk proteins ---- Lactoperoxidase Source.83: DFBPPR7707 ---- Milk proteins ---- Early lactation protein Source.84: DFBPPR7712 ---- Milk proteins ---- Lactoperoxidase Source.85: DFBPPR8370 ---- Plant proteins ---- Maturase K Source.86: DFBPPR8419 ---- Plant proteins ---- Arachin 21 kDa protein Source.87: DFBPPR8420 ---- Plant proteins ---- Peroxygenase Source.88: DFBPPR8459 ---- Plant proteins ---- Carbon catabolite-derepressing protein kinase Source.89: DFBPPR8495 ---- Milk proteins ---- Angiogenin-1 Source.90: DFBPPR8497 ---- Milk proteins ---- Lactoperoxidase Source.91: DFBPPR15945 ---- Animal proteins ---- Dopamine beta-hydroxylase Source.92: DFBPPR16012 ---- Animal proteins ---- Mast/stem cell growth factor receptor Kit Source.93: DFBPPR16023 ---- Animal proteins ---- Platelet-derived growth factor receptor beta Source.94: DFBPPR16045 ---- Animal proteins ---- Endoplasmin Source.95: DFBPPR16054 ---- Animal proteins ---- Hepatocyte growth factor receptor Source.96: DFBPPR16061 ---- Animal proteins ---- Hepatocyte growth factor Source.97: DFBPPR16124 ---- Animal proteins ---- Serine/threonine-protein kinase greatwall Source.98: DFBPPR16164 ---- Animal proteins ---- Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 Source.99: DFBPPR16178 ---- Animal proteins ---- Wee1-like protein kinase 2 Source.100: DFBPPR16203 ---- Animal proteins ---- E3 ubiquitin-protein ligase RING1 Source.101: DFBPPR16440 ---- Animal proteins ---- Inactive rhomboid protein 2 Source.102: DFBPPR16461 ---- Animal proteins ---- InaD-like protein Source.103: DFBPPR16501 ---- Animal proteins ---- F-box/LRR-repeat protein 15 Source.104: DFBPPR16523 ---- Animal proteins ---- Hepatocyte growth factor activator Source.105: DFBPPR16575 ---- Animal proteins ---- Dystrophin Source.106: DFBPPR16614 ---- Animal proteins ---- Protein S100-A4 Source.107: DFBPPR16814 ---- Animal proteins ---- Prothrombin Source.108: DFBPPR16831 ---- Animal proteins ---- Fibrinogen beta chain Source.109: DFBPPR16864 ---- Animal proteins ---- Protein AMBP Source.110: DFBPPR16871 ---- Animal proteins ---- Plasminogen Source.111: DFBPPR16923 ---- Animal proteins ---- TNF receptor-associated factor 6 Source.112: DFBPPR16929 ---- Animal proteins ---- N-acetyllactosaminide alpha-1,3-galactosyltransferase Source.113: DFBPPR16932 ---- Animal proteins ---- Heat shock protein HSP 90-beta Source.114: DFBPPR16944 ---- Animal proteins ---- Platelet-activating factor acetylhydrolase 2, cytoplasmic Source.115: DFBPPR16968 ---- Animal proteins ---- Inhibitor of nuclear factor kappa-B kinase subunit beta Source.116: DFBPPR17001 ---- Animal proteins ---- Serine/threonine-protein kinase 4 Source.117: DFBPPR17019 ---- Animal proteins ---- Mast/stem cell growth factor receptor Kit Source.118: DFBPPR17025 ---- Animal proteins ---- Tissue-type plasminogen activator Source.119: DFBPPR17050 ---- Animal proteins ---- Heat shock protein HSP 90-alpha Source.120: DFBPPR17066 ---- Animal proteins ---- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Source.121: DFBPPR17124 ---- Animal proteins ---- Inhibitor of nuclear factor kappa-B kinase subunit alpha Source.122: DFBPPR17131 ---- Animal proteins ---- Hepatocyte growth factor receptor Source.123: DFBPPR17299 ---- Animal proteins ---- Dynamin-1-like protein Source.124: DFBPPR17338 ---- Animal proteins ---- Unconventional myosin-VI Source.125: DFBPPR17348 ---- Animal proteins ---- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 Source.126: DFBPPR17367 ---- Animal proteins ---- Cyclic GMP-AMP synthase Source.127: DFBPPR17374 ---- Animal proteins ---- Inositol 1,4,5-trisphosphate receptor type 1 Source.128: DFBPPR17384 ---- Animal proteins ---- Alpha-actinin-1 Source.129: DFBPPR17460 ---- Animal proteins ---- Endoplasmin Source.130: DFBPPR17496 ---- Animal proteins ---- Unconventional myosin-Id Source.131: DFBPPR17535 ---- Animal proteins ---- Atrial natriuretic peptide receptor 2 Source.132: DFBPPR17569 ---- Animal proteins ---- Platelet endothelial cell adhesion molecule Source.133: DFBPPR17591 ---- Animal proteins ---- 72 kDa type IV collagenase Source.134: DFBPPR17634 ---- Animal proteins ---- Hypoxia-inducible factor 1-alpha Source.135: DFBPPR17678 ---- Animal proteins ---- Ubiquitin carboxyl-terminal hydrolase 16 Source.136: DFBPPR17893 ---- Animal proteins ---- Inositol 1,4,5-trisphosphate receptor type 3 Source.137: DFBPPR17910 ---- Animal proteins ---- Mitogen-activated protein kinase kinase kinase 13 Source.138: DFBPPR17931 ---- Animal proteins ---- Alpha-actinin-3 Source.139: DFBPPR17939 ---- Animal proteins ---- Delta(14)-sterol reductase TM7SF2 Source.140: DFBPPR18059 ---- Animal proteins ---- Ubiquitin thioesterase OTU1 Source.141: DFBPPR18089 ---- Animal proteins ---- Coatomer subunit delta Source.142: DFBPPR18094 ---- Animal proteins ---- Neutrophil cytosol factor 1 Source.143: DFBPPR18161 ---- Animal proteins ---- Disintegrin and metalloproteinase domain-containing protein 2 Source.144: DFBPPR18163 ---- Animal proteins ---- Ectonucleoside triphosphate diphosphohydrolase 1 Source.145: DFBPPR18164 ---- Animal proteins ---- Thromboxane-A synthase Source.146: DFBPPR18167 ---- Animal proteins ---- Ubiquitin thioesterase ZRANB1 Source.147: DFBPPR18236 ---- Animal proteins ---- Latent-transforming growth factor beta-binding protein 2 Source.148: DFBPPR18399 ---- Animal proteins ---- Integrin beta-6 Source.149: DFBPPR18424 ---- Animal proteins ---- Inositol 1,4,5-trisphosphate receptor type 2 Source.150: DFBPPR18540 ---- Animal proteins ---- Fibroblast growth factor-binding protein 1 Source.151: DFBPPR18634 ---- Animal proteins ---- Methylmalonyl-CoA mutase, mitochondrial Source.152: DFBPPR18637 ---- Animal proteins ---- Protein S100-A4 Source.153: DFBPPR18773 ---- Animal proteins ---- E3 ubiquitin-protein ligase TRIM9 Source.154: DFBPPR18790 ---- Animal proteins ---- Proto-oncogene vav Source.155: DFBPPR18819 ---- Animal proteins ---- Proteasome activator complex subunit 4 Source.156: DFBPPR18859 ---- Animal proteins ---- Matrix remodeling-associated protein 8 Source.157: DFBPPR18869 ---- Animal proteins ---- Geranylgeranyl transferase type-2 subunit beta Source.158: DFBPPR18887 ---- Animal proteins ---- Zinc finger X-chromosomal protein Source.159: DFBPPR18992 ---- Animal proteins ---- Coatomer subunit beta Source.160: DFBPPR19111 ---- Animal proteins ---- Mitochondrial Rho GTPase 1 Source.161: DFBPPR19195 ---- Animal proteins ---- V-type proton ATPase 116 kDa subunit a2 Source.162: DFBPPR19202 ---- Animal proteins ---- Zinc finger protein 639 Source.163: DFBPPR19218 ---- Animal proteins ---- Mitotic checkpoint protein BUB3 Source.164: DFBPPR19242 ---- Animal proteins ---- Tryptophan 2,3-dioxygenase Source.165: DFBPPR19259 ---- Animal proteins ---- Protein transport protein Sec16B Source.166: DFBPPR19365 ---- Animal proteins ---- Inactive rhomboid protein 1 Source.167: DFBPPR19409 ---- Animal proteins ---- Hyaluronan-binding protein 2 Source.168: DFBPPR19449 ---- Animal proteins ---- SCO-spondin Source.169: DFBPPR19669 ---- Animal proteins ---- Cullin-associated NEDD8-dissociated protein 1 Source.170: DFBPPR19761 ---- Animal proteins ---- N-chimaerin Source.171: DFBPPR19767 ---- Animal proteins ---- F-box/LRR-repeat protein 15 Source.172: DFBPPR19799 ---- Animal proteins ---- Migration and invasion enhancer 1 Source.173: DFBPPR19813 ---- Animal proteins ---- Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Source.174: DFBPPR19901 ---- Animal proteins ---- Aspartate--tRNA ligase, cytoplasmic Source.175: DFBPPR19908 ---- Animal proteins ---- DNA replication licensing factor MCM6 Source.176: DFBPPR19961 ---- Animal proteins ---- Sulfate transporter Source.177: DFBPPR20026 ---- Animal proteins ---- Mitochondrial ribosome-associated GTPase 1 Source.178: DFBPPR20081 ---- Animal proteins ---- ADP-ribosylation factor-related protein 1 Source.179: DFBPPR20092 ---- Animal proteins ---- Peptidyl-tRNA hydrolase 2, mitochondrial Source.180: DFBPPR20265 ---- Animal proteins ---- Histone-lysine N-methyltransferase EZH1 Source.181: DFBPPR20420 ---- Animal proteins ---- Hepatocyte growth factor Source.182: DFBPPR20603 ---- Animal proteins ---- Craniofacial development protein 2 Source.183: DFBPPR20611 ---- Animal proteins ---- Engulfment and cell motility protein 2 Source.184: DFBPPR20696 ---- Animal proteins ---- Protein shisa-2 homolog Source.185: DFBPPR20711 ---- Animal proteins ---- Transcription elongation factor, mitochondrial Source.186: DFBPPR20810 ---- Animal proteins ---- Zinc finger protein 148 Source.187: DFBPPR20867 ---- Animal proteins ---- Protein BUD31 homolog Source.188: DFBPPR20901 ---- Animal proteins ---- [Protein ADP-ribosylarginine] hydrolase-like protein 1 Source.189: DFBPPR20928 ---- Animal proteins ---- Nuclear envelope integral membrane protein 1 Source.190: DFBPPR20933 ---- Animal proteins ---- FAST kinase domain-containing protein 3, mitochondrial Source.191: DFBPPR21269 ---- Animal proteins ---- TOX high mobility group box family member 4 Source.192: DFBPPR21329 ---- Animal proteins ---- L-2-hydroxyglutarate dehydrogenase, mitochondrial Source.193: DFBPPR21350 ---- Animal proteins ---- Nuclear apoptosis-inducing factor 1 Source.194: DFBPPR21460 ---- Animal proteins ---- SREBP regulating gene protein Source.195: DFBPPR21463 ---- Animal proteins ---- Protein BEX2 Source.196: DFBPPR21472 ---- Animal proteins ---- Rho guanine nucleotide exchange factor 9 Source.197: DFBPPR21580 ---- Animal proteins ---- Density-regulated protein Source.198: DFBPPR21747 ---- Animal proteins ---- Zinc finger Y-chromosomal protein Source.199: DFBPPR21846 ---- Animal proteins ---- Izumo sperm-egg fusion protein 3 Source.200: DFBPPR22215 ---- Animal proteins ---- General transcription factor II-I repeat domain-containing protein 2 Source.201: DFBPPR22406 ---- Animal proteins ---- Uncharacterized protein KIAA2013 homolog Source.202: DFBPPR8553 ---- Animal proteins ---- Protein AMBP Source.203: DFBPPR8580 ---- Animal proteins ---- Aldo-keto reductase family 1 member B1 Source.204: DFBPPR8621 ---- Animal proteins ---- Amyloid-beta A4 protein Source.205: DFBPPR8689 ---- Animal proteins ---- Wee1-like protein kinase 2 Source.206: DFBPPR8692 ---- Animal proteins ---- TNF receptor-associated factor 6 Source.207: DFBPPR8695 ---- Animal proteins ---- Mast/stem cell growth factor receptor Kit Source.208: DFBPPR8705 ---- Animal proteins ---- Unconventional myosin-VI Source.209: DFBPPR8727 ---- Animal proteins ---- Cyclic GMP-AMP synthase Source.210: DFBPPR8740 ---- Animal proteins ---- Hepatocyte growth factor receptor Source.211: DFBPPR8742 ---- Animal proteins ---- Low-density lipoprotein receptor-related protein 2 Source.212: DFBPPR8786 ---- Animal proteins ---- Heat shock protein HSP 90-alpha Source.213: DFBPPR8792 ---- Animal proteins ---- Plasminogen Source.214: DFBPPR8820 ---- Animal proteins ---- Ectonucleoside triphosphate diphosphohydrolase 1 Source.215: DFBPPR8896 ---- Animal proteins ---- Heat-stable enterotoxin receptor Source.216: DFBPPR8954 ---- Animal proteins ---- N-acetyllactosaminide alpha-1,3-galactosyltransferase Source.217: DFBPPR9022 ---- Animal proteins ---- Prothrombin Source.218: DFBPPR9027 ---- Animal proteins ---- Phosphatidylcholine:ceramide cholinephosphotransferase 1 Source.219: DFBPPR9107 ---- Animal proteins ---- Tissue-type plasminogen activator Source.220: DFBPPR9121 ---- Animal proteins ---- Endoplasmin Source.221: DFBPPR9132 ---- Animal proteins ---- Dystrophin Source.222: DFBPPR9180 ---- Animal proteins ---- Integrin beta-6 Source.223: DFBPPR9225 ---- Animal proteins ---- Methylmalonyl-CoA mutase, mitochondrial Source.224: DFBPPR9258 ---- Animal proteins ---- Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Source.225: DFBPPR9264 ---- Animal proteins ---- Dual specificity phosphatase 29 Source.226: DFBPPR9344 ---- Animal proteins ---- Desmoglein-1 Source.227: DFBPPR9400 ---- Animal proteins ---- Prostaglandin E2 receptor EP3 subtype Source.228: DFBPPR9507 ---- Animal proteins ---- Coatomer subunit beta Source.229: DFBPPR9535 ---- Animal proteins ---- Ribonuclease inhibitor Source.230: DFBPPR9545 ---- Animal proteins ---- Thioredoxin reductase 1, cytoplasmic Source.231: DFBPPR9952 ---- Animal proteins ---- Serine/threonine-protein kinase TAO3 Source.232: DFBPPR10035 ---- Animal proteins ---- 72 kDa type IV collagenase Source.233: DFBPPR10075 ---- Animal proteins ---- Mast/stem cell growth factor receptor Kit Source.234: DFBPPR10077 ---- Animal proteins ---- Heat shock protein HSP 90-alpha Source.235: DFBPPR10131 ---- Animal proteins ---- Alpha-actinin-1 Source.236: DFBPPR10174 ---- Animal proteins ---- Serine/threonine-protein kinase SIK2 Source.237: DFBPPR10175 ---- Animal proteins ---- Platelet-derived growth factor receptor alpha Source.238: DFBPPR10192 ---- Animal proteins ---- Vascular endothelial growth factor receptor 1 Source.239: DFBPPR10210 ---- Animal proteins ---- Fibroblast growth factor receptor 1 Source.240: DFBPPR10227 ---- Animal proteins ---- Serine/threonine-protein kinase STK11 Source.241: DFBPPR10236 ---- Animal proteins ---- Acid-sensing ion channel 1 Source.242: DFBPPR10237 ---- Animal proteins ---- Serine/threonine-protein kinase Chk1 Source.243: DFBPPR10282 ---- Animal proteins ---- Reversion-inducing cysteine-rich protein with Kazal motifs Source.244: DFBPPR10300 ---- Animal proteins ---- Unconventional myosin-Va Source.245: DFBPPR10378 ---- Animal proteins ---- Muscle, skeletal receptor tyrosine protein kinase Source.246: DFBPPR10384 ---- Animal proteins ---- Myosin-binding protein C, cardiac-type Source.247: DFBPPR10398 ---- Animal proteins ---- Inhibitor of nuclear factor kappa-B kinase subunit alpha Source.248: DFBPPR10411 ---- Animal proteins ---- DNA-dependent protein kinase catalytic subunit Source.249: DFBPPR10432 ---- Animal proteins ---- Endoplasmin Source.250: DFBPPR10448 ---- Animal proteins ---- Serine/threonine-protein kinase 4 Source.251: DFBPPR10589 ---- Animal proteins ---- Amiloride-sensitive sodium channel subunit alpha Source.252: DFBPPR10608 ---- Animal proteins ---- Semaphorin-3D Source.253: DFBPPR10691 ---- Animal proteins ---- Beclin-1 Source.254: DFBPPR10716 ---- Animal proteins ---- Long-chain-fatty-acid--CoA ligase ACSBG2 Source.255: DFBPPR10735 ---- Animal proteins ---- Semaphorin-3E Source.256: DFBPPR10743 ---- Animal proteins ---- Phosphatidylcholine:ceramide cholinephosphotransferase 1 Source.257: DFBPPR10769 ---- Animal proteins ---- Ubiquitin thioesterase OTU1 Source.258: DFBPPR10780 ---- Animal proteins ---- Caspase-2 Source.259: DFBPPR10807 ---- Animal proteins ---- Dystrophin Source.260: DFBPPR10958 ---- Animal proteins ---- Heat shock cognate protein HSP 90-beta Source.261: DFBPPR11010 ---- Animal proteins ---- Alpha-actinin-4 Source.262: DFBPPR11046 ---- Animal proteins ---- Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Source.263: DFBPPR11052 ---- Animal proteins ---- Protein cornichon homolog 2 Source.264: DFBPPR11096 ---- Animal proteins ---- WASH complex subunit 1 Source.265: DFBPPR11106 ---- Animal proteins ---- Aryl hydrocarbon receptor nuclear translocator-like protein 2 Source.266: DFBPPR11171 ---- Animal proteins ---- Coatomer subunit delta Source.267: DFBPPR11172 ---- Animal proteins ---- Protein transport protein Sec16B Source.268: DFBPPR11195 ---- Animal proteins ---- Mitochondrial Rho GTPase 1 Source.269: DFBPPR11234 ---- Animal proteins ---- Bleomycin hydrolase Source.270: DFBPPR11402 ---- Animal proteins ---- Contactin-associated protein-like 5 Source.271: DFBPPR11491 ---- Animal proteins ---- Vacuolar protein sorting-associated protein 53 homolog Source.272: DFBPPR11553 ---- Animal proteins ---- V-type proton ATPase 116 kDa subunit a1 Source.273: DFBPPR11582 ---- Animal proteins ---- Coatomer subunit beta Source.274: DFBPPR11659 ---- Animal proteins ---- Matrix remodeling-associated protein 8 Source.275: DFBPPR11903 ---- Animal proteins ---- SREBP regulating gene protein Source.276: DFBPPR11931 ---- Animal proteins ---- Mediator of RNA polymerase II transcription subunit 20 Source.277: DFBPPR11938 ---- Animal proteins ---- Nuclear apoptosis-inducing factor 1 Source.278: DFBPPR11961 ---- Animal proteins ---- KIF-binding protein Source.279: DFBPPR12018 ---- Animal proteins ---- Density-regulated protein Source.280: DFBPPR12143 ---- Animal proteins ---- Basic leucine zipper and W2 domain-containing protein 2 Source.281: DFBPPR12200 ---- Animal proteins ---- Basic leucine zipper and W2 domain-containing protein 1 Source.282: DFBPPR12407 ---- Animal proteins ---- Heat shock protein HSP 90-beta Source.283: DFBPPR12415 ---- Animal proteins ---- 72 kDa type IV collagenase Source.284: DFBPPR12423 ---- Animal proteins ---- Hepatocyte growth factor receptor Source.285: DFBPPR12444 ---- Animal proteins ---- C->U-editing enzyme APOBEC-1 Source.286: DFBPPR12480 ---- Animal proteins ---- Heat shock protein HSP 90-alpha Source.287: DFBPPR12515 ---- Animal proteins ---- Amiloride-sensitive sodium channel subunit alpha Source.288: DFBPPR12541 ---- Animal proteins ---- Disintegrin and metalloproteinase domain-containing protein 2 Source.289: DFBPPR12592 ---- Animal proteins ---- Amiloride-sensitive sodium channel subunit beta Source.290: DFBPPR12710 ---- Animal proteins ---- Endoplasmin Source.291: DFBPPR12870 ---- Animal proteins ---- Protein transport protein Sec16B Source.292: DFBPPR13010 ---- Animal proteins ---- Sodium- and chloride-dependent betaine transporter Source.293: DFBPPR13147 ---- Animal proteins ---- Heat shock protein HSP 90-beta Source.294: DFBPPR13171 ---- Animal proteins ---- Hepatocyte growth factor receptor Source.295: DFBPPR13189 ---- Animal proteins ---- Heat shock protein HSP 90-alpha Source.296: DFBPPR13286 ---- Animal proteins ---- Inter-alpha-trypsin inhibitor Source.297: DFBPPR13340 ---- Animal proteins ---- Sulfate transporter Source.298: DFBPPR13427 ---- Animal proteins ---- Mast/stem cell growth factor receptor Kit Source.299: DFBPPR13478 ---- Animal proteins ---- Inter-alpha-trypsin inhibitor Source.300: DFBPPR13585 ---- Animal proteins ---- Hepatocyte growth factor receptor Source.301: DFBPPR13642 ---- Animal proteins ---- Integrin beta-6 Source.302: DFBPPR13855 ---- Animal proteins ---- Inter-alpha-trypsin inhibitor Source.303: DFBPPR13904 ---- Animal proteins ---- Sulfate transporter Source.304: DFBPPR14128 ---- Marine protein ---- F-box/LRR-repeat protein 15 Source.305: DFBPPR14581 ---- Marine protein ---- Interferon alpha/beta receptor 2 Source.306: DFBPPR14894 ---- Microorganism protein ---- Serine/threonine-protein kinase ATG1 Source.307: DFBPPR14924 ---- Microorganism protein ---- E3 ubiquitin-protein ligase UBR1 Source.308: DFBPPR14943 ---- Microorganism protein ---- Nuclear protein localization protein 4 Source.309: DFBPPR14961 ---- Microorganism protein ---- Alcohol dehydrogenase 1 Source.310: DFBPPR14994 ---- Microorganism protein ---- Serine/threonine-protein kinase MEC1 Source.311: DFBPPR15000 ---- Microorganism protein ---- D-lactate dehydrogenase [cytochrome], mitochondrial Source.312: DFBPPR15017 ---- Microorganism protein ---- Serine/threonine-protein kinase TEL1 Source.313: DFBPPR15092 ---- Microorganism protein ---- Alcohol dehydrogenase 3, mitochondrial Source.314: DFBPPR15095 ---- Microorganism protein ---- Endoplasmic reticulum oxidoreductin-1 Source.315: DFBPPR15186 ---- Microorganism protein ---- Alcohol dehydrogenase 2 Source.316: DFBPPR15365 ---- Microorganism protein ---- Inositol-pentakisphosphate 2-kinase Source.317: DFBPPR15625 ---- Microorganism protein ---- DNA polymerase Source.318: DFBPPR15652 ---- Microorganism protein ---- Translation machinery-associated protein 22 Source.319: DFBPPR7795 ---- Plant protein ---- NAD(P)H-quinone oxidoreductase subunit I, chloroplastic Source.320: DFBPPR8064 ---- Plant protein ---- Endochitinase PR4 Source.321: DFBPPR8066 ---- Plant protein ---- NAD(P)H-quinone oxidoreductase subunit I, chloroplastic Source.322: DFBPPR8134 ---- Plant protein ---- 30S ribosomal protein S3, chloroplastic Source.323: DFBPPR8236 ---- Plant protein ---- NAD(P)H-quinone oxidoreductase subunit I, chloroplastic
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

ACE-inhibitory activity	The peptide EYC showed moderate Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) inhibitory activity with an IC₅₀ value of 217.58 ± 6.47 μM.
Specific target protein(s)	Specific Target Protein(s): Angiotensin-converting enzyme

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Bitter taste ^prediction

SMILES

N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CS)C(=O)O

Preparation method

Mode of preparation	Enzymatic hydrolysis
Enzyme(s)/starter culture	Korat-chicken breast and thigh were subjected to heating at 70, 100 or 121 ℃ for 30 min and simulated in vitro gastrointestinal digestion.

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

This study demonstrated that cooked Korat chicken breast is a promising precursor source of ACE inhibitor peptides that are permeable.

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Sangsawad P, Roytrakul S, Choowongkomon K, Kitts DD, Chen XM, Meng G, Li-Chan ECY, Yongsawatdigul J. Transepithelial transport across Caco-2 cell monolayers of angiotensin converting enzyme (ACE) inhibitory peptides derived from simulated in vitro gastrointestinal digestion of cooked chicken muscles. Food Chem. 2018 Jun 15;251:77-85. PMID: 29426427 DOI: 10.1016/j.foodchem.2018.01.047
Other literature(s)	N.D
PubDate	2018