Table 1 show the effects of ACE inhibitory peptide GFHI on three Gram-positive (B. cereus, L. monocytogens, and S. aureus) and three Gram-negative (S. Typhimurium, E. Coli, and P. aeruginosa) pathogens. This peptide had a very strong antimicrobial effect, especially on E. coli and P. aeruginosa at 200 and 400 μg/ml.
Table 1. Antimicrobial activity of the synthetic peptide GFHI on six pathogens
Concentration (μg)
| Microorganisms
| S. Typhimurium
| B. cereus
| E. coli
| L. monoytogenes
| S. aureus
| P. aeruginosa
| 100
| —
| —
| + | —
| —
| ++
| 200
| —
| —
| ++ | —
| —
| ++
| 400
| —
| —
| ++ | —
| —
| ++
| ++, Very sensitive (13–18 mm inhibition); +, sensitive (9–12 mm inhibition); –, not detected. | |