As is obvious in Fig. 4A, 2 h after the administration of ovokinin (2-7) at a dose of 20 mg/kg, the systolic blood pressure of SHRs started to decrease, with the significant effect observed 4 and 6 h post-administration. The maximal effect was dose-dependently noted 6 h after administration (Fig. 4B). On the other hand, ovokinin(2-7) at a dose of 20 mg/kg did not show any significant hypotensive effect in WKYs (Fig. 4B).

Ovalbumin was hydrolyzed with chymotrypsin.

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