Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPANTH0009(Antithrombotic peptide)

DFBP ID	DFBPANTH0009
Peptide sequence	GPRG
Type	Native peptide
Peptide/Function name	Antithrombotic peptide

Function-activity relationship

Main bioactivity	Antithrombotic activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

Gly-Pro-Arg-Gly

Single-letter amino acid

GPRG

Peptide length

Peptide mass

Experimental mass	Theoretical mass
N.D	385.42 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

11.04 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

-1.7250^c

Hydrophilic residue ratio

75%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Animal
Organism/Source	Pig
Precursor protein	Porcine skin collagen
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR0841 ---- Plant proteins ---- Catalase isozyme A Source.2: DFBPPR1256 ---- Plant proteins ---- Cytochrome P450 78A11 Source.3: DFBPPR1305 ---- Plant proteins ---- Alpha-amylase isozyme 3A Source.4: DFBPPR1342 ---- Plant proteins ---- KH domain-containing protein SPIN1 Source.5: DFBPPR1518 ---- Plant proteins ---- GATA transcription factor 15 Source.6: DFBPPR1528 ---- Plant proteins ---- Cyclin-dependent kinase C-2 Source.7: DFBPPR1617 ---- Plant proteins ---- DNA replication licensing factor MCM7 Source.8: DFBPPR1721 ---- Plant proteins ---- Cyclin-dependent kinase C-1 Source.9: DFBPPR1802 ---- Plant proteins ---- Flavonoid 3'-monooxygenase CYP75B3 Source.10: DFBPPR1950 ---- Plant proteins ---- Flavonoid 3'-monooxygenase CYP75B4 Source.11: DFBPPR2023 ---- Plant proteins ---- Mitogen-activated protein kinase 9 Source.12: DFBPPR2091 ---- Plant proteins ---- Cellulose synthase-like protein D3 Source.13: DFBPPR2120 ---- Plant proteins ---- Putative cyclin-dependent kinase F-2 Source.14: DFBPPR2123 ---- Plant proteins ---- Ninja-family protein MODD Source.15: DFBPPR2310 ---- Plant proteins ---- Heat stress transcription factor A-3 Source.16: DFBPPR2351 ---- Plant proteins ---- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit Source.17: DFBPPR2355 ---- Plant proteins ---- Probable glycosyltransferase 5 Source.18: DFBPPR2567 ---- Plant proteins ---- Origin of replication complex subunit 4 Source.19: DFBPPR2731 ---- Plant proteins ---- Eukaryotic translation initiation factor 4G Source.20: DFBPPR3004 ---- Plant proteins ---- Long chain base biosynthesis protein 1a Source.21: DFBPPR3214 ---- Plant proteins ---- Probable adenylate kinase 5, chloroplastic Source.22: DFBPPR3280 ---- Plant proteins ---- Long chain base biosynthesis protein 1b Source.23: DFBPPR3336 ---- Plant proteins ---- Photosystem I reaction center subunit VI, chloroplastic Source.24: DFBPPR3497 ---- Plant proteins ---- Potassium channel KAT4 Source.25: DFBPPR3576 ---- Plant proteins ---- Transport inhibitor response 1-like protein Os11g0515500 Source.26: DFBPPR3784 ---- Plant proteins ---- Potassium channel KAT6 Source.27: DFBPPR3821 ---- Plant proteins ---- Kinesin-like protein KIN-7G Source.28: DFBPPR4007 ---- Plant proteins ---- Zinc-finger homeodomain protein 7 Source.29: DFBPPR4053 ---- Plant proteins ---- Protein argonaute 1B Source.30: DFBPPR4333 ---- Plant proteins ---- Putative potassium channel KAT5 Source.31: DFBPPR4460 ---- Plant proteins ---- Protein argonaute 3 Source.32: DFBPPR4658 ---- Plant proteins ---- 60S ribosomal protein L9 Source.33: DFBPPR4706 ---- Plant proteins ---- Tubby-like protein 4 Source.34: DFBPPR4726 ---- Plant proteins ---- 40S ribosomal protein S10-2 Source.35: DFBPPR4815 ---- Plant proteins ---- 40S ribosomal protein S10-1 Source.36: DFBPPR4847 ---- Plant proteins ---- B3 domain-containing protein Os07g0183200 Source.37: DFBPPR5350 ---- Plant proteins ---- Wound-induced protein Source.38: DFBPPR5399 ---- Plant proteins ---- Catalase isozyme 3 Source.39: DFBPPR5426 ---- Plant proteins ---- Dimethylnonatriene synthase Source.40: DFBPPR5478 ---- Plant proteins ---- 1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic Source.41: DFBPPR5495 ---- Plant proteins ---- Trimethyltridecatetraene synthase Source.42: DFBPPR5546 ---- Plant proteins ---- Thiamine thiazole synthase 1, chloroplastic Source.43: DFBPPR5925 ---- Plant proteins ---- Photosystem I reaction center subunit VI, chloroplastic Source.44: DFBPPR6327 ---- Plant proteins ---- Serine hydroxymethyltransferase, mitochondrial Source.45: DFBPPR6365 ---- Plant proteins ---- RuBisCO large subunit-binding protein subunit alpha, chloroplastic Source.46: DFBPPR6494 ---- Plant proteins ---- 50S ribosomal protein L1, chloroplastic Source.47: DFBPPR6563 ---- Plant proteins ---- 60S ribosomal protein L9 Source.48: DFBPPR6719 ---- Plant proteins ---- RuBisCO large subunit-binding protein subunit alpha, chloroplastic Source.49: DFBPPR6927 ---- Plant proteins ---- Eukaryotic translation initiation factor isoform 4G-1 Source.50: DFBPPR6952 ---- Plant proteins ---- Eukaryotic translation initiation factor isoform 4G-2 Source.51: DFBPPR7016 ---- Plant proteins ---- Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic Source.52: DFBPPR7125 ---- Plant proteins ---- Catalase isozyme 2 Source.53: DFBPPR7172 ---- Plant proteins ---- Barwin Source.54: DFBPPR7217 ---- Plant proteins ---- Photosystem I reaction center subunit VI, chloroplastic Source.55: DFBPPR7460 ---- Plant proteins ---- RuBisCO large subunit-binding protein subunit alpha, chloroplastic Source.56: DFBPPR7462 ---- Plant proteins ---- RuBisCO large subunit-binding protein subunit alpha, chloroplastic Source.57: DFBPPR7640 ---- Milk proteins ---- Pro-neuregulin-1, membrane-bound isoform Source.58: DFBPPR7643 ---- Milk proteins ---- MICAL-like protein 1 Source.59: DFBPPR8458 ---- Plant proteins ---- Catalase Source.60: DFBPPR8518 ---- Milk proteins ---- MICAL-like protein 1 Source.61: DFBPPR15935 ---- Animal proteins ---- Catalase Source.62: DFBPPR16048 ---- Animal proteins ---- Collagen alpha-1(I) chain Source.63: DFBPPR16105 ---- Animal proteins ---- Collagen alpha-1(XVII) chain Source.64: DFBPPR16114 ---- Animal proteins ---- Collagen alpha-5(IV) chain Source.65: DFBPPR16284 ---- Animal proteins ---- Collagen alpha-2(I) chain Source.66: DFBPPR16523 ---- Animal proteins ---- Hepatocyte growth factor activator Source.67: DFBPPR16597 ---- Animal proteins ---- Cholecystokinin receptor type A Source.68: DFBPPR16707 ---- Animal proteins ---- Trefoil factor 2 Source.69: DFBPPR16712 ---- Animal proteins ---- RNA-binding protein 47 Source.70: DFBPPR16803 ---- Animal proteins ---- Pro-opiomelanocortin Source.71: DFBPPR16842 ---- Animal proteins ---- Collagen alpha-1(II) chain Source.72: DFBPPR16851 ---- Animal proteins ---- Cytochrome c1, heme protein, mitochondrial Source.73: DFBPPR16960 ---- Animal proteins ---- Catalase Source.74: DFBPPR17010 ---- Animal proteins ---- Sestrin-2 Source.75: DFBPPR17088 ---- Animal proteins ---- Collagen alpha-2(I) chain Source.76: DFBPPR17140 ---- Animal proteins ---- Adiponectin Source.77: DFBPPR17162 ---- Animal proteins ---- Collagen alpha-1(IV) chain Source.78: DFBPPR17165 ---- Animal proteins ---- Cytochrome b-245 heavy chain Source.79: DFBPPR17360 ---- Animal proteins ---- Collagen alpha-1(I) chain Source.80: DFBPPR17412 ---- Animal proteins ---- Fragile X mental retardation syndrome-related protein 1 Source.81: DFBPPR17450 ---- Animal proteins ---- Adhesion G protein-coupled receptor L3 Source.82: DFBPPR17483 ---- Animal proteins ---- Speckle targeted PIP5K1A-regulated poly(A) polymerase Source.83: DFBPPR17613 ---- Animal proteins ---- Collagen alpha-1(XVII) chain Source.84: DFBPPR17778 ---- Animal proteins ---- Integrin alpha-V Source.85: DFBPPR17782 ---- Animal proteins ---- Ras GTPase-activating protein-binding protein 1 Source.86: DFBPPR18096 ---- Animal proteins ---- Serine palmitoyltransferase 1 Source.87: DFBPPR18216 ---- Animal proteins ---- Collectin-12 Source.88: DFBPPR18252 ---- Animal proteins ---- Collagen alpha-4(IV) chain Source.89: DFBPPR18421 ---- Animal proteins ---- Matrix metalloproteinase-20 Source.90: DFBPPR18435 ---- Animal proteins ---- Paraspeckle component 1 Source.91: DFBPPR18479 ---- Animal proteins ---- Pyruvate dehydrogenase protein X component Source.92: DFBPPR18537 ---- Animal proteins ---- Collagen alpha-1(III) chain Source.93: DFBPPR18608 ---- Animal proteins ---- ATP-dependent RNA helicase DHX30 Source.94: DFBPPR18673 ---- Animal proteins ---- Isobutyryl-CoA dehydrogenase, mitochondrial Source.95: DFBPPR18720 ---- Animal proteins ---- Protein quaking Source.96: DFBPPR18794 ---- Animal proteins ---- LIM domain-containing protein ajuba Source.97: DFBPPR18813 ---- Animal proteins ---- Acyl-CoA synthetase short-chain family member 3, mitochondrial Source.98: DFBPPR18818 ---- Animal proteins ---- Protein-tyrosine sulfotransferase 2 Source.99: DFBPPR18865 ---- Animal proteins ---- Collagen alpha-1(XI) chain Source.100: DFBPPR18978 ---- Animal proteins ---- Membrane-bound transcription factor site-2 protease Source.101: DFBPPR19033 ---- Animal proteins ---- Collagen alpha-2(XI) chain Source.102: DFBPPR19049 ---- Animal proteins ---- Caprin-1 Source.103: DFBPPR19120 ---- Animal proteins ---- Collagen alpha-1(X) chain Source.104: DFBPPR19182 ---- Animal proteins ---- Protoporphyrinogen oxidase Source.105: DFBPPR19298 ---- Animal proteins ---- T-complex protein 1 subunit eta Source.106: DFBPPR19316 ---- Animal proteins ---- Histidine triad nucleotide-binding protein 2, mitochondrial Source.107: DFBPPR19357 ---- Animal proteins ---- Collagen alpha-2(IX) chain Source.108: DFBPPR19406 ---- Animal proteins ---- [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial Source.109: DFBPPR19544 ---- Animal proteins ---- Marginal zone B- and B1-cell-specific protein Source.110: DFBPPR19730 ---- Animal proteins ---- Tensin-1 Source.111: DFBPPR19792 ---- Animal proteins ---- Cleavage stimulation factor subunit 2 Source.112: DFBPPR19811 ---- Animal proteins ---- Mitochondrial inner membrane protein OXA1L Source.113: DFBPPR19849 ---- Animal proteins ---- 4-hydroxybenzoate polyprenyltransferase, mitochondrial Source.114: DFBPPR19981 ---- Animal proteins ---- Zinc finger protein AEBP2 Source.115: DFBPPR20122 ---- Animal proteins ---- Mediator of RNA polymerase II transcription subunit 25 Source.116: DFBPPR20182 ---- Animal proteins ---- DnaJ homolog subfamily B member 6 Source.117: DFBPPR20285 ---- Animal proteins ---- Probable G-protein coupled receptor 158 Source.118: DFBPPR20352 ---- Animal proteins ---- Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase Source.119: DFBPPR20428 ---- Animal proteins ---- Rab effector Noc2 Source.120: DFBPPR20487 ---- Animal proteins ---- Multifunctional methyltransferase subunit TRM112-like protein Source.121: DFBPPR20593 ---- Animal proteins ---- Pro-interleukin-16 Source.122: DFBPPR20599 ---- Animal proteins ---- Cleavage and polyadenylation specificity factor subunit 1 Source.123: DFBPPR20658 ---- Animal proteins ---- G-protein coupled receptor family C group 5 member C Source.124: DFBPPR20796 ---- Animal proteins ---- Up-regulator of cell proliferation Source.125: DFBPPR20820 ---- Animal proteins ---- D-2-hydroxyglutarate dehydrogenase, mitochondrial Source.126: DFBPPR20861 ---- Animal proteins ---- Zinc finger protein 135 Source.127: DFBPPR20885 ---- Animal proteins ---- Zinc transporter ZIP3 Source.128: DFBPPR21159 ---- Animal proteins ---- Origin recognition complex subunit 4 Source.129: DFBPPR21248 ---- Animal proteins ---- 39S ribosomal protein L4, mitochondrial Source.130: DFBPPR21282 ---- Animal proteins ---- Spindle and centriole-associated protein 1 Source.131: DFBPPR21311 ---- Animal proteins ---- WD repeat-containing protein 18 Source.132: DFBPPR21361 ---- Animal proteins ---- Seizure protein 6 homolog Source.133: DFBPPR21715 ---- Animal proteins ---- Junctional protein associated with coronary artery disease homolog Source.134: DFBPPR22028 ---- Animal proteins ---- Endonuclease/exonuclease/phosphatase family domain-containing protein 1 Source.135: DFBPPR22130 ---- Animal proteins ---- 60S ribosomal protein L9 Source.136: DFBPPR22241 ---- Animal proteins ---- von Willebrand factor A domain-containing protein 7 Source.137: DFBPPR22334 ---- Animal proteins ---- Protein HP-25 homolog 1 Source.138: DFBPPR22387 ---- Animal proteins ---- Sterile alpha motif domain-containing protein 5 Source.139: DFBPPR22397 ---- Animal proteins ---- NHL repeat-containing protein 2 Source.140: DFBPPR22449 ---- Animal proteins ---- Complement C1q and tumor necrosis factor-related protein 9 Source.141: DFBPPR22609 ---- Animal proteins ---- Protein TSSC4 Source.142: DFBPPR22616 ---- Animal proteins ---- Jhy protein homolog Source.143: DFBPPR22708 ---- Animal proteins ---- Pregnancy-associated protein bPAP Source.144: DFBPPR8569 ---- Animal proteins ---- Ryanodine receptor 1 Source.145: DFBPPR8576 ---- Animal proteins ---- Hormone-sensitive lipase Source.146: DFBPPR8756 ---- Animal proteins ---- Pro-opiomelanocortin Source.147: DFBPPR8992 ---- Animal proteins ---- Hyaluronidase-3 Source.148: DFBPPR9177 ---- Animal proteins ---- Matrix metalloproteinase-20 Source.149: DFBPPR9205 ---- Animal proteins ---- Pulmonary surfactant-associated protein D Source.150: DFBPPR9221 ---- Animal proteins ---- Catalase Source.151: DFBPPR9222 ---- Animal proteins ---- Glutathione peroxidase 1 Source.152: DFBPPR9427 ---- Animal proteins ---- Protein quaking Source.153: DFBPPR9706 ---- Animal proteins ---- Homeobox protein Hox-B8 Source.154: DFBPPR9735 ---- Animal proteins ---- SLA class II histocompatibility antigen, DQ haplotype C alpha chain Source.155: DFBPPR9981 ---- Animal proteins ---- Collagen alpha-1(I) chain Source.156: DFBPPR9985 ---- Animal proteins ---- Collagen alpha-1(II) chain Source.157: DFBPPR10138 ---- Animal proteins ---- Epidermal growth factor receptor Source.158: DFBPPR10160 ---- Animal proteins ---- Collagen alpha-2(I) chain Source.159: DFBPPR10216 ---- Animal proteins ---- Pro-neuregulin-1, membrane-bound isoform Source.160: DFBPPR10417 ---- Animal proteins ---- Cytochrome P450 1A5 Source.161: DFBPPR10422 ---- Animal proteins ---- Collagen alpha-1(XII) chain Source.162: DFBPPR10445 ---- Animal proteins ---- Collagen alpha-1(XVII) chain Source.163: DFBPPR10470 ---- Animal proteins ---- Collagen alpha-1(III) chain Source.164: DFBPPR10498 ---- Animal proteins ---- Cytochrome P450 1A4 Source.165: DFBPPR10512 ---- Animal proteins ---- Collagen alpha-1(XIV) chain Source.166: DFBPPR10520 ---- Animal proteins ---- Collagen alpha-2(IX) chain Source.167: DFBPPR10528 ---- Animal proteins ---- Far upstream element-binding protein 2 Source.168: DFBPPR10594 ---- Animal proteins ---- Aromatase Source.169: DFBPPR10603 ---- Animal proteins ---- Collagen alpha-3(VI) chain Source.170: DFBPPR10607 ---- Animal proteins ---- Collagen alpha-2(VI) chain Source.171: DFBPPR10749 ---- Animal proteins ---- DnaJ homolog subfamily B member 6 Source.172: DFBPPR10801 ---- Animal proteins ---- Collagen alpha-1(VI) chain Source.173: DFBPPR10820 ---- Animal proteins ---- Collagen alpha-1(IX) chain Source.174: DFBPPR10825 ---- Animal proteins ---- Collagen alpha-3(IX) chain Source.175: DFBPPR10880 ---- Animal proteins ---- Golgi apparatus protein 1 Source.176: DFBPPR10969 ---- Animal proteins ---- Paraspeckle component 1 Source.177: DFBPPR11017 ---- Animal proteins ---- Collectin-12 Source.178: DFBPPR11049 ---- Animal proteins ---- Potassium voltage-gated channel subfamily H member 6 Source.179: DFBPPR11058 ---- Animal proteins ---- Proteasome subunit beta type-5 Source.180: DFBPPR11112 ---- Animal proteins ---- Protein quaking Source.181: DFBPPR11297 ---- Animal proteins ---- Prohibitin-2 Source.182: DFBPPR11374 ---- Animal proteins ---- Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 Source.183: DFBPPR11462 ---- Animal proteins ---- Collagen alpha-1(VIII) chain Source.184: DFBPPR11585 ---- Animal proteins ---- Acyl-CoA-binding domain-containing protein 5 Source.185: DFBPPR11621 ---- Animal proteins ---- T-cell leukemia homeobox protein 3 Source.186: DFBPPR11727 ---- Animal proteins ---- Peroxisomal targeting signal 1 receptor Source.187: DFBPPR11779 ---- Animal proteins ---- T-complex protein 1 subunit eta Source.188: DFBPPR12020 ---- Animal proteins ---- Lipase maturation factor 2 Source.189: DFBPPR12151 ---- Animal proteins ---- NHL repeat-containing protein 2 Source.190: DFBPPR12281 ---- Animal proteins ---- Ryanodine receptor 1 Source.191: DFBPPR12485 ---- Animal proteins ---- Potassium-transporting ATPase alpha chain 2 Source.192: DFBPPR12592 ---- Animal proteins ---- Amiloride-sensitive sodium channel subunit beta Source.193: DFBPPR12666 ---- Animal proteins ---- Collagen alpha-2(I) chain Source.194: DFBPPR12746 ---- Animal proteins ---- Collagen alpha-4(IV) chain Source.195: DFBPPR12756 ---- Animal proteins ---- Aromatase Source.196: DFBPPR12772 ---- Animal proteins ---- Colipase Source.197: DFBPPR12786 ---- Animal proteins ---- Intercellular adhesion molecule 5 Source.198: DFBPPR12859 ---- Animal proteins ---- Collagen alpha-1(VIII) chain Source.199: DFBPPR12861 ---- Animal proteins ---- Leukocyte cell-derived chemotaxin 1 Source.200: DFBPPR12870 ---- Animal proteins ---- Protein transport protein Sec16B Source.201: DFBPPR12977 ---- Animal proteins ---- Collagen alpha-1(I) chain Source.202: DFBPPR13002 ---- Animal proteins ---- Complement component C8 gamma chain Source.203: DFBPPR13276 ---- Animal proteins ---- Protein quaking Source.204: DFBPPR13287 ---- Animal proteins ---- 1,4-alpha-glucan-branching enzyme Source.205: DFBPPR13531 ---- Animal proteins ---- Pro-opiomelanocortin Source.206: DFBPPR14240 ---- Marine protein ---- Otolin-1 Source.207: DFBPPR14438 ---- Marine protein ---- 50S ribosomal protein L1, chloroplastic Source.208: DFBPPR14516 ---- Marine protein ---- Uncharacterized protein ycf53 Source.209: DFBPPR14569 ---- Marine protein ---- Collagen alpha-2(I) chain Source.210: DFBPPR14617 ---- Marine protein ---- Na(+)/H(+) exchanger beta Source.211: DFBPPR14660 ---- Marine protein ---- Otolin-1 Source.212: DFBPPR14987 ---- Microorganism protein ---- Serine hydroxymethyltransferase, mitochondrial Source.213: DFBPPR15204 ---- Microorganism protein ---- FK506-binding protein 1 Source.214: DFBPPR15407 ---- Microorganism protein ---- Mitochondrial escape protein 2 Source.215: DFBPPR15855 ---- Microorganism protein ---- 5-aminolevulinate synthase, mitochondrial
Link-research Inductive analysis	Link 1: DFBPANTH0065----Pig----Porcine skin collagen

Biological/Functional activity & target protein

Antithrombotic activity

GPRG inhibited fibrinogen/thrombin clotting to some degree, but did not inhibit the activity of thrombin.

Table 1 Inhibitory effects of collagen-related synthetic peptides on fibrinogen / thrombin clotting
Peptide	IC50 (μM)	References
Gly-Pro-Arg	250	[1]
Gly-Pro-Arg-Pro	110	[1]
Gly-Pro-Arg-Gly	510	-
Gly-Pro-Arg-Gly-Pro	380
Gly-Pro-Arg-Gly-Pro-Ala	260
Gly-Pro-Arg-Gly-Pro-Pro	230
Gly-Pro-Arg-Pro-Pro	50
Gly-Pro-Arg-Gly-Pro-NH₂	40	[2]

Specific target protein(s)

Potential Target Protein(s):
Fibrinogen gamma chain
Fibrinogen alpha chain
Fibrinogen beta chain
Fibroleukin

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Non-bitter taste ^prediction

SMILES

NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)NCC(=O)O

Preparation method

Mode of preparation	Synthetic peptide
Enzyme(s)/starter culture	The peptide was synthesized by the solid-phase method with a 430A Peptide Synthesizer (Applied Biosystems).

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Maruyama, S., Nonaka, I., Tanaka, H. Inhibitory effects of enzymatic hydrolysates of collagen and collagen-related synthetic peptides on fibrinogen/thrombin clotting. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1993, 1164, 215-8. DOI: 10.1016/0167-4838(93)90250-U
Other literature(s)	[1] Laudano A P, Doolittle R F. Studies on synthetic peptides that bind to fibrinogen and prevent fibrin polymerization. Structural requirements, number of binding sites, and species differences.[J]. Biochemistry, 1980, 19(5):1013-1019. [2] Kawasaki K, Hirase K, Tsuji T, et al. Amino acids and peptides XII: synthetic peptides related to the N-terminal portion of fibrin alpha-chain and their inhibitory effects on fibrinogen/thrombin clotting.[J]. Thrombosis Research, 1989, 56(6):757-762.
PubDate	1993