Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPPEPI0090(PEP-inhibitory peptide)

DFBP ID	DFBPPEPI0090
Peptide sequence	APPA
Type	Native peptide
Peptide/Function name	PEP-inhibitory peptide

Function-activity relationship

Main bioactivity	PEP-inhibitory activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

Ala-Pro-Pro-Ala

Single-letter amino acid

APPA

Peptide length

Peptide mass

Experimental mass	Theoretical mass
N.D	354.39 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

5.97 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

0.1000^c

Hydrophilic residue ratio

100%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Animal
Organism/Source	Bovine
Precursor protein	Brain
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR0835 ---- Plant proteins ---- WRKY transcription factor WRKY71 Source.2: DFBPPR0856 ---- Plant proteins ---- Gibberellin 20 oxidase 2 Source.3: DFBPPR0898 ---- Plant proteins ---- Protein phosphatase 2C 53 Source.4: DFBPPR0939 ---- Plant proteins ---- Protein argonaute MEL1 Source.5: DFBPPR0947 ---- Plant proteins ---- Histone-lysine N-methyltransferase TRX1 Source.6: DFBPPR0948 ---- Plant proteins ---- Carotenoid cleavage dioxygenase 8 homolog B, chloroplastic Source.7: DFBPPR0978 ---- Plant proteins ---- Transcription factor MYBS1 Source.8: DFBPPR0980 ---- Plant proteins ---- Ketol-acid reductoisomerase, chloroplastic Source.9: DFBPPR1015 ---- Plant proteins ---- Ent-kaurene oxidase 2 Source.10: DFBPPR1057 ---- Plant proteins ---- Abscisic acid receptor PYL10 Source.11: DFBPPR1061 ---- Plant proteins ---- Cinnamyl alcohol dehydrogenase 2 Source.12: DFBPPR1083 ---- Plant proteins ---- WRKY transcription factor WRKY24 Source.13: DFBPPR1087 ---- Plant proteins ---- Protein TPR1 Source.14: DFBPPR1096 ---- Plant proteins ---- Peptide deformylase 1B, chloroplastic Source.15: DFBPPR1100 ---- Plant proteins ---- Soluble starch synthase 2-3, chloroplastic/amyloplastic Source.16: DFBPPR1110 ---- Plant proteins ---- Superoxide dismutase [Cu-Zn], chloroplastic Source.17: DFBPPR1126 ---- Plant proteins ---- Gibberellin 2-beta-dioxygenase 6 Source.18: DFBPPR1131 ---- Plant proteins ---- Gibberellin 2-beta-dioxygenase 1 Source.19: DFBPPR1145 ---- Plant proteins ---- Acetolactate synthase 1, chloroplastic Source.20: DFBPPR1208 ---- Plant proteins ---- RNA polymerase sigma factor sigA Source.21: DFBPPR1253 ---- Plant proteins ---- Phospholipase A2 homolog 3 Source.22: DFBPPR1259 ---- Plant proteins ---- Beta-carotene isomerase D27, chloroplastic Source.23: DFBPPR1290 ---- Plant proteins ---- Dehydration-responsive element-binding protein 2B Source.24: DFBPPR1291 ---- Plant proteins ---- 6-phosphogluconate dehydrogenase, decarboxylating 2, chloroplastic Source.25: DFBPPR1296 ---- Plant proteins ---- Zinc finger protein STAMENLESS 1 Source.26: DFBPPR1324 ---- Plant proteins ---- Calcium-dependent protein kinase 11 Source.27: DFBPPR1333 ---- Plant proteins ---- Endoglucanase 2 Source.28: DFBPPR1413 ---- Plant proteins ---- ATP synthase subunit beta, mitochondrial Source.29: DFBPPR1441 ---- Plant proteins ---- Cysteine protease 1 Source.30: DFBPPR1457 ---- Plant proteins ---- Inositol-tetrakisphosphate 1-kinase 3 Source.31: DFBPPR1459 ---- Plant proteins ---- Protein TIFY 10c Source.32: DFBPPR1466 ---- Plant proteins ---- Hexokinase-1 Source.33: DFBPPR1498 ---- Plant proteins ---- Protein SCARECROW 2 Source.34: DFBPPR1536 ---- Plant proteins ---- Protein DWARF 53 Source.35: DFBPPR1553 ---- Plant proteins ---- Transcription factor LG2 Source.36: DFBPPR1582 ---- Plant proteins ---- Homeobox-leucine zipper protein HOX4 Source.37: DFBPPR1585 ---- Plant proteins ---- Carbamoyl-phosphate synthase small chain, chloroplastic Source.38: DFBPPR1602 ---- Plant proteins ---- SNW/SKI-interacting protein A Source.39: DFBPPR1628 ---- Plant proteins ---- Polyprotein of EF-Ts, chloroplastic Source.40: DFBPPR1707 ---- Plant proteins ---- Probable histidine kinase 2 Source.41: DFBPPR1722 ---- Plant proteins ---- Protein TIFY 11a Source.42: DFBPPR1739 ---- Plant proteins ---- Ribose-phosphate pyrophosphokinase 2, chloroplastic Source.43: DFBPPR1753 ---- Plant proteins ---- Protein TPR3 Source.44: DFBPPR1765 ---- Plant proteins ---- Transcription factor MYC2 Source.45: DFBPPR1801 ---- Plant proteins ---- Transcription factor MYB4 Source.46: DFBPPR1806 ---- Plant proteins ---- Laccase-19 Source.47: DFBPPR1852 ---- Plant proteins ---- RAP domain-containing protein, chloroplastic Source.48: DFBPPR1870 ---- Plant proteins ---- Laccase-20 Source.49: DFBPPR1889 ---- Plant proteins ---- Laccase-18 Source.50: DFBPPR2011 ---- Plant proteins ---- Lipoyl synthase 1, chloroplastic Source.51: DFBPPR2067 ---- Plant proteins ---- Protein kinase PINOID 2 Source.52: DFBPPR2121 ---- Plant proteins ---- Cellulose synthase-like protein D5 Source.53: DFBPPR2330 ---- Plant proteins ---- Probable staphylococcal-like nuclease CAN3 Source.54: DFBPPR2343 ---- Plant proteins ---- Protein kinase G11A Source.55: DFBPPR2377 ---- Plant proteins ---- 21.9 kDa heat shock protein Source.56: DFBPPR2426 ---- Plant proteins ---- Transcription factor NIGT1 Source.57: DFBPPR2445 ---- Plant proteins ---- Protein IRON-RELATED TRANSCRIPTION FACTOR 3 Source.58: DFBPPR2455 ---- Plant proteins ---- Auxin response factor 4 Source.59: DFBPPR2528 ---- Plant proteins ---- Probable staphylococcal-like nuclease CAN2 Source.60: DFBPPR2561 ---- Plant proteins ---- Probable inorganic phosphate transporter 1-4 Source.61: DFBPPR2569 ---- Plant proteins ---- MADS-box transcription factor 20 Source.62: DFBPPR2602 ---- Plant proteins ---- Homeobox-leucine zipper protein HOX19 Source.63: DFBPPR2621 ---- Plant proteins ---- Germin-like protein 4-1 Source.64: DFBPPR2710 ---- Plant proteins ---- 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic Source.65: DFBPPR2809 ---- Plant proteins ---- Retinoblastoma-related protein 1 Source.66: DFBPPR2844 ---- Plant proteins ---- Splicing factor U2af large subunit B Source.67: DFBPPR2859 ---- Plant proteins ---- Proton pump-interactor BIP131 Source.68: DFBPPR2869 ---- Plant proteins ---- Homeobox-leucine zipper protein HOX11 Source.69: DFBPPR2887 ---- Plant proteins ---- Probable protein phosphatase 2C 32 Source.70: DFBPPR2975 ---- Plant proteins ---- Hydroxycinnamoyltransferase 4 Source.71: DFBPPR2977 ---- Plant proteins ---- Nicotinate-nucleotide pyrophosphorylase [carboxylating], chloroplastic Source.72: DFBPPR2996 ---- Plant proteins ---- Transcription factor PCF1 Source.73: DFBPPR3005 ---- Plant proteins ---- tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like Source.74: DFBPPR3031 ---- Plant proteins ---- Ent-kaurene oxidase-like protein 1 Source.75: DFBPPR3100 ---- Plant proteins ---- Kinesin-like protein KIN-14E Source.76: DFBPPR3131 ---- Plant proteins ---- Ribonuclease III domain-containing protein RNC1, chloroplastic Source.77: DFBPPR3152 ---- Plant proteins ---- Acyl-[acyl-carrier-protein] desaturase 3, chloroplastic Source.78: DFBPPR3219 ---- Plant proteins ---- Secretory carrier-associated membrane protein 4 Source.79: DFBPPR3255 ---- Plant proteins ---- COBRA-like protein 6 Source.80: DFBPPR3324 ---- Plant proteins ---- Dehydration-responsive element-binding protein 2C Source.81: DFBPPR3331 ---- Plant proteins ---- RNA pseudouridine synthase 3, mitochondrial Source.82: DFBPPR3362 ---- Plant proteins ---- Probable alpha-glucosidase Os06g0675700 Source.83: DFBPPR3405 ---- Plant proteins ---- Auxin-responsive protein IAA1 Source.84: DFBPPR3430 ---- Plant proteins ---- Dehydrin DHN1 Source.85: DFBPPR3441 ---- Plant proteins ---- Chloroplastic group IIA intron splicing facilitator CRS1, chloroplastic Source.86: DFBPPR3463 ---- Plant proteins ---- Protein THYLAKOID RHODANESE-LIKE, chloroplastic Source.87: DFBPPR3482 ---- Plant proteins ---- Probable inactive heme oxygenase 2, chloroplastic Source.88: DFBPPR3503 ---- Plant proteins ---- Kinesin-like protein KIN-14P Source.89: DFBPPR3511 ---- Plant proteins ---- Kinesin-like protein KIN-14N Source.90: DFBPPR3534 ---- Plant proteins ---- Cardiolipin synthase (CMP-forming), mitochondrial Source.91: DFBPPR3564 ---- Plant proteins ---- Probable protein phosphatase 2C 36 Source.92: DFBPPR3590 ---- Plant proteins ---- Histidine--tRNA ligase, cytoplasmic Source.93: DFBPPR3598 ---- Plant proteins ---- Mitochondrial outer membrane protein porin 2 Source.94: DFBPPR3608 ---- Plant proteins ---- Probable RNA-dependent RNA polymerase 3 Source.95: DFBPPR3638 ---- Plant proteins ---- 4-coumarate--CoA ligase-like 6 Source.96: DFBPPR3647 ---- Plant proteins ---- Dof zinc finger protein 2 Source.97: DFBPPR3655 ---- Plant proteins ---- Fe-S cluster assembly factor HCF101, chloroplastic Source.98: DFBPPR3772 ---- Plant proteins ---- Putative 12-oxophytodienoate reductase 9 Source.99: DFBPPR3832 ---- Plant proteins ---- 26.2 kDa heat shock protein, mitochondrial Source.100: DFBPPR3906 ---- Plant proteins ---- Protein G1-like8 Source.101: DFBPPR3925 ---- Plant proteins ---- Squamosa promoter-binding-like protein 5 Source.102: DFBPPR3948 ---- Plant proteins ---- Probable anion transporter 5, chloroplastic Source.103: DFBPPR4008 ---- Plant proteins ---- Putative serpin-Z12 Source.104: DFBPPR4012 ---- Plant proteins ---- Protein G1-like5 Source.105: DFBPPR4073 ---- Plant proteins ---- Auxin-responsive protein IAA5 Source.106: DFBPPR4110 ---- Plant proteins ---- Cyclin-A3-2 Source.107: DFBPPR4132 ---- Plant proteins ---- Zinc finger CCCH domain-containing protein 49 Source.108: DFBPPR4175 ---- Plant proteins ---- Formin-like protein 1 Source.109: DFBPPR4205 ---- Plant proteins ---- DEAD-box ATP-dependent RNA helicase 24 Source.110: DFBPPR4232 ---- Plant proteins ---- Formin-like protein 14 Source.111: DFBPPR4238 ---- Plant proteins ---- Putative magnesium transporter MRS2-H Source.112: DFBPPR4240 ---- Plant proteins ---- Protein DWARF 53-LIKE Source.113: DFBPPR4242 ---- Plant proteins ---- Flotillin-like protein 3 Source.114: DFBPPR4253 ---- Plant proteins ---- Zinc-finger homeodomain protein 5 Source.115: DFBPPR4256 ---- Plant proteins ---- Copper transporter 4 Source.116: DFBPPR4342 ---- Plant proteins ---- Nucleolin 1 Source.117: DFBPPR4356 ---- Plant proteins ---- Mitochondrial outer membrane protein porin 4 Source.118: DFBPPR4361 ---- Plant proteins ---- Formin-like protein 8 Source.119: DFBPPR4371 ---- Plant proteins ---- Protein NLP3 Source.120: DFBPPR4414 ---- Plant proteins ---- Formin-like protein 4 Source.121: DFBPPR4446 ---- Plant proteins ---- Lecithin-cholesterol acyltransferase-like 1 Source.122: DFBPPR4475 ---- Plant proteins ---- Protein argonaute 14 Source.123: DFBPPR4480 ---- Plant proteins ---- Formin-like protein 7 Source.124: DFBPPR4481 ---- Plant proteins ---- Formin-like protein 12 Source.125: DFBPPR4484 ---- Plant proteins ---- Protein argonaute 12 Source.126: DFBPPR4594 ---- Plant proteins ---- Probable calcium-binding protein CML21 Source.127: DFBPPR4665 ---- Plant proteins ---- Zinc finger CCCH domain-containing protein 24 Source.128: DFBPPR4690 ---- Plant proteins ---- Zinc finger CCCH domain-containing protein 44 Source.129: DFBPPR4695 ---- Plant proteins ---- SNW/SKI-interacting protein B Source.130: DFBPPR4698 ---- Plant proteins ---- Cyclin-dependent kinase inhibitor 2 Source.131: DFBPPR4719 ---- Plant proteins ---- Zinc finger CCCH domain-containing protein 50 Source.132: DFBPPR4721 ---- Plant proteins ---- Protein YY1 Source.133: DFBPPR4722 ---- Plant proteins ---- Zinc finger A20 and AN1 domain-containing stress-associated protein 10 Source.134: DFBPPR4725 ---- Plant proteins ---- Zinc finger CCCH domain-containing protein 19 Source.135: DFBPPR4744 ---- Plant proteins ---- BURP domain-containing protein 3 Source.136: DFBPPR4794 ---- Plant proteins ---- Putative B3 domain-containing protein Os04g0346900 Source.137: DFBPPR4848 ---- Plant proteins ---- B3 domain-containing protein Os02g0455800 Source.138: DFBPPR4863 ---- Plant proteins ---- Protein MOTHER of FT and TFL1 homolog 1 Source.139: DFBPPR4886 ---- Plant proteins ---- DELLA protein SLR1 Source.140: DFBPPR4913 ---- Plant proteins ---- LRR receptor kinase SERL2 Source.141: DFBPPR4914 ---- Plant proteins ---- Serine/threonine-protein kinase BSK1-2 Source.142: DFBPPR5215 ---- Plant proteins ---- Probable phytol kinase 2, chloroplastic Source.143: DFBPPR5218 ---- Plant proteins ---- Arginine decarboxylase Source.144: DFBPPR5396 ---- Plant proteins ---- DELLA protein DWARF8 Source.145: DFBPPR5398 ---- Plant proteins ---- Sulfite reductase [ferredoxin], chloroplastic Source.146: DFBPPR5454 ---- Plant proteins ---- Ferredoxin-dependent glutamate synthase, chloroplastic Source.147: DFBPPR5564 ---- Plant proteins ---- Acetolactate synthase 1, chloroplastic Source.148: DFBPPR5572 ---- Plant proteins ---- CRM-domain containing factor CFM3, chloroplastic/mitochondrial Source.149: DFBPPR5577 ---- Plant proteins ---- Acetolactate synthase 2, chloroplastic Source.150: DFBPPR5579 ---- Plant proteins ---- Indole-3-acetaldehyde oxidase Source.151: DFBPPR5687 ---- Plant proteins ---- Protein AMEIOTIC 1 Source.152: DFBPPR5709 ---- Plant proteins ---- indolin-2-one monooxygenase Source.153: DFBPPR5755 ---- Plant proteins ---- Protein Iojap, chloroplastic Source.154: DFBPPR5862 ---- Plant proteins ---- Probable phytol kinase, chloroplastic Source.155: DFBPPR5870 ---- Plant proteins ---- Protein WRKY1 Source.156: DFBPPR5920 ---- Plant proteins ---- Cell number regulator 1 Source.157: DFBPPR5952 ---- Plant proteins ---- WUSCHEL-related homeobox 3B Source.158: DFBPPR5996 ---- Plant proteins ---- Myb-related protein Zm1 Source.159: DFBPPR6015 ---- Plant proteins ---- Casparian strip membrane protein 2 Source.160: DFBPPR6283 ---- Plant proteins ---- Ketol-acid reductoisomerase, chloroplastic Source.161: DFBPPR6389 ---- Plant proteins ---- Auxin-induced protein IAA4 Source.162: DFBPPR6693 ---- Plant proteins ---- Phosphoglycerate kinase, chloroplastic Source.163: DFBPPR6753 ---- Plant proteins ---- Ferredoxin, chloroplastic Source.164: DFBPPR6884 ---- Plant proteins ---- Endogenous alpha-amylase/subtilisin inhibitor Source.165: DFBPPR6931 ---- Plant proteins ---- Eukaryotic translation initiation factor NCBP Source.166: DFBPPR7079 ---- Plant proteins ---- Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, chloroplastic Source.167: DFBPPR7085 ---- Plant proteins ---- Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY Source.168: DFBPPR7116 ---- Plant proteins ---- Alpha-amylase/subtilisin inhibitor Source.169: DFBPPR7173 ---- Plant proteins ---- Photosystem I reaction center subunit II, chloroplastic Source.170: DFBPPR7203 ---- Plant proteins ---- Betaine aldehyde dehydrogenase Source.171: DFBPPR7214 ---- Plant proteins ---- Alpha-glucosidase Source.172: DFBPPR7407 ---- Plant proteins ---- Oleosin-B1 Source.173: DFBPPR7418 ---- Plant proteins ---- Oleosin-B6 Source.174: DFBPPR7622 ---- Milk proteins ---- Mucin-1 Source.175: DFBPPR15940 ---- Animal proteins ---- Thyroid transcription factor 1 Source.176: DFBPPR16034 ---- Animal proteins ---- Progesterone receptor Source.177: DFBPPR16047 ---- Animal proteins ---- Adenylate cyclase type 5 Source.178: DFBPPR16087 ---- Animal proteins ---- 5-hydroxytryptamine receptor 1B Source.179: DFBPPR16109 ---- Animal proteins ---- Vasodilator-stimulated phosphoprotein Source.180: DFBPPR16266 ---- Animal proteins ---- Beta-1 adrenergic receptor Source.181: DFBPPR16272 ---- Animal proteins ---- Thrombopoietin Source.182: DFBPPR16456 ---- Animal proteins ---- Ribosome-binding protein 1 Source.183: DFBPPR16575 ---- Animal proteins ---- Dystrophin Source.184: DFBPPR16592 ---- Animal proteins ---- T-box transcription factor TBX4 Source.185: DFBPPR16626 ---- Animal proteins ---- RING finger protein unkempt homolog Source.186: DFBPPR16638 ---- Animal proteins ---- Synapsin-1 Source.187: DFBPPR16662 ---- Animal proteins ---- Rab GDP dissociation inhibitor beta Source.188: DFBPPR16671 ---- Animal proteins ---- Forkhead box protein I3 Source.189: DFBPPR16685 ---- Animal proteins ---- Bromodomain-containing protein 2 Source.190: DFBPPR16903 ---- Animal proteins ---- Myristoylated alanine-rich C-kinase substrate Source.191: DFBPPR17056 ---- Animal proteins ---- Protein-lysine 6-oxidase Source.192: DFBPPR17083 ---- Animal proteins ---- Cyclin-dependent kinase 5 activator 1 Source.193: DFBPPR17157 ---- Animal proteins ---- AP2-associated protein kinase 1 Source.194: DFBPPR17426 ---- Animal proteins ---- DNA polymerase delta catalytic subunit Source.195: DFBPPR17489 ---- Animal proteins ---- Adhesion G protein-coupled receptor L2 Source.196: DFBPPR17537 ---- Animal proteins ---- Sphingomyelin phosphodiesterase Source.197: DFBPPR17569 ---- Animal proteins ---- Platelet endothelial cell adhesion molecule Source.198: DFBPPR17644 ---- Animal proteins ---- CCAAT/enhancer-binding protein beta Source.199: DFBPPR17744 ---- Animal proteins ---- Protein argonaute-2 Source.200: DFBPPR17773 ---- Animal proteins ---- Adenosylhomocysteinase 3 Source.201: DFBPPR17810 ---- Animal proteins ---- Histone H1.2 Source.202: DFBPPR17860 ---- Animal proteins ---- Leucine-rich repeat and fibronectin type-III domain-containing protein 3 Source.203: DFBPPR17909 ---- Animal proteins ---- Solute carrier family 2, facilitated glucose transporter member 8 Source.204: DFBPPR17927 ---- Animal proteins ---- Synaptojanin-1 Source.205: DFBPPR17941 ---- Animal proteins ---- Hepatocyte growth factor-regulated tyrosine kinase substrate Source.206: DFBPPR17943 ---- Animal proteins ---- Transport and Golgi organization protein 1 homolog Source.207: DFBPPR17949 ---- Animal proteins ---- Insulinoma-associated protein 1 Source.208: DFBPPR17984 ---- Animal proteins ---- Phosphatidylinositol 3-kinase regulatory subunit beta Source.209: DFBPPR18072 ---- Animal proteins ---- Postacrosomal sheath WW domain-binding protein Source.210: DFBPPR18108 ---- Animal proteins ---- Vesicular glutamate transporter 1 Source.211: DFBPPR18122 ---- Animal proteins ---- Microtubule-associated protein 4 Source.212: DFBPPR18128 ---- Animal proteins ---- Gap junction alpha-3 protein Source.213: DFBPPR18130 ---- Animal proteins ---- CCAAT/enhancer-binding protein alpha Source.214: DFBPPR18299 ---- Animal proteins ---- Synapsin-1 Source.215: DFBPPR18329 ---- Animal proteins ---- Coatomer subunit epsilon Source.216: DFBPPR18344 ---- Animal proteins ---- Monofunctional C1-tetrahydrofolate synthase, mitochondrial Source.217: DFBPPR18362 ---- Animal proteins ---- Cyclic nucleotide-gated olfactory channel Source.218: DFBPPR18429 ---- Animal proteins ---- Pre-mRNA-splicing factor SLU7 Source.219: DFBPPR18473 ---- Animal proteins ---- Sharpin Source.220: DFBPPR18494 ---- Animal proteins ---- Prostacyclin receptor Source.221: DFBPPR18560 ---- Animal proteins ---- Rho-related GTP-binding protein RhoF Source.222: DFBPPR18563 ---- Animal proteins ---- Collectin-43 Source.223: DFBPPR18780 ---- Animal proteins ---- Homeobox protein Hox-A3 Source.224: DFBPPR18888 ---- Animal proteins ---- Glutathione hydrolase 6 Source.225: DFBPPR18889 ---- Animal proteins ---- Achaete-scute homolog 2 Source.226: DFBPPR18946 ---- Animal proteins ---- Paternally-expressed gene 3 protein Source.227: DFBPPR18960 ---- Animal proteins ---- Spondin-1 Source.228: DFBPPR19018 ---- Animal proteins ---- Interferon regulatory factor 5 Source.229: DFBPPR19052 ---- Animal proteins ---- Rab GDP dissociation inhibitor beta Source.230: DFBPPR19067 ---- Animal proteins ---- Prostaglandin E2 receptor EP4 subtype Source.231: DFBPPR19254 ---- Animal proteins ---- Periaxin Source.232: DFBPPR19295 ---- Animal proteins ---- 26S proteasome regulatory subunit 7 Source.233: DFBPPR19329 ---- Animal proteins ---- CD302 antigen Source.234: DFBPPR19359 ---- Animal proteins ---- Spartin Source.235: DFBPPR19388 ---- Animal proteins ---- Deoxyhypusine hydroxylase Source.236: DFBPPR19416 ---- Animal proteins ---- Gamma-glutamyl hydrolase Source.237: DFBPPR19449 ---- Animal proteins ---- SCO-spondin Source.238: DFBPPR19466 ---- Animal proteins ---- N-acylglucosamine 2-epimerase Source.239: DFBPPR19475 ---- Animal proteins ---- Coronin-7 Source.240: DFBPPR19515 ---- Animal proteins ---- Protein strawberry notch homolog 2 Source.241: DFBPPR19722 ---- Animal proteins ---- Cdc42 effector protein 1 Source.242: DFBPPR19740 ---- Animal proteins ---- Sin3 histone deacetylase corepressor complex component SDS3 Source.243: DFBPPR19758 ---- Animal proteins ---- MICOS complex subunit MIC25 Source.244: DFBPPR19779 ---- Animal proteins ---- Hepatocyte nuclear factor 3-gamma Source.245: DFBPPR19870 ---- Animal proteins ---- CCAAT/enhancer-binding protein delta Source.246: DFBPPR19879 ---- Animal proteins ---- TBC1 domain family member 14 Source.247: DFBPPR19963 ---- Animal proteins ---- DnaJ homolog subfamily C member 14 Source.248: DFBPPR20122 ---- Animal proteins ---- Mediator of RNA polymerase II transcription subunit 25 Source.249: DFBPPR20123 ---- Animal proteins ---- Securin Source.250: DFBPPR20423 ---- Animal proteins ---- 39S ribosomal protein L16, mitochondrial Source.251: DFBPPR20610 ---- Animal proteins ---- Cleft lip and palate transmembrane protein 1 homolog Source.252: DFBPPR20615 ---- Animal proteins ---- Seizure 6-like protein 2 Source.253: DFBPPR20722 ---- Animal proteins ---- Serine beta-lactamase-like protein LACTB, mitochondrial Source.254: DFBPPR20794 ---- Animal proteins ---- Rab-like protein 6 Source.255: DFBPPR20878 ---- Animal proteins ---- Protein SMG9 Source.256: DFBPPR20934 ---- Animal proteins ---- Early growth response protein 4 Source.257: DFBPPR21006 ---- Animal proteins ---- AT-rich interactive domain-containing protein 5A Source.258: DFBPPR21098 ---- Animal proteins ---- Pre T-cell antigen receptor alpha Source.259: DFBPPR21101 ---- Animal proteins ---- Bromodomain-containing protein 2 Source.260: DFBPPR21216 ---- Animal proteins ---- UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 Source.261: DFBPPR21317 ---- Animal proteins ---- Gap junction alpha-4 protein Source.262: DFBPPR21367 ---- Animal proteins ---- DNA-directed RNA polymerase II subunit RPB11 Source.263: DFBPPR21444 ---- Animal proteins ---- DAZ-associated protein 2 Source.264: DFBPPR21492 ---- Animal proteins ---- Homeobox protein DBX1 Source.265: DFBPPR21588 ---- Animal proteins ---- Diazepam-binding inhibitor-like 5 Source.266: DFBPPR21635 ---- Animal proteins ---- Regulator of G-protein signaling 19 Source.267: DFBPPR21734 ---- Animal proteins ---- TBC1 domain family member 1 Source.268: DFBPPR21770 ---- Animal proteins ---- Cbp/p300-interacting transactivator 4 Source.269: DFBPPR21923 ---- Animal proteins ---- Endophilin-B2 Source.270: DFBPPR21968 ---- Animal proteins ---- F-box only protein 28 Source.271: DFBPPR22111 ---- Animal proteins ---- Homeobox protein Hox-A5 Source.272: DFBPPR22146 ---- Animal proteins ---- Leucine-rich repeat-containing protein 41 Source.273: DFBPPR22316 ---- Animal proteins ---- MAPK-interacting and spindle-stabilizing protein-like Source.274: DFBPPR22454 ---- Animal proteins ---- R3H domain-containing protein 4 Source.275: DFBPPR22476 ---- Animal proteins ---- Major facilitator superfamily domain-containing protein 1 Source.276: DFBPPR22760 ---- Animal proteins ---- Uncharacterized protein C7orf57 homolog Source.277: DFBPPR8578 ---- Animal proteins ---- Large proline-rich protein BAG6 Source.278: DFBPPR8613 ---- Animal proteins ---- Thyroglobulin Source.279: DFBPPR8679 ---- Animal proteins ---- Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Source.280: DFBPPR8703 ---- Animal proteins ---- AP2-associated protein kinase 1 Source.281: DFBPPR8706 ---- Animal proteins ---- Cellular tumor antigen p53 Source.282: DFBPPR8716 ---- Animal proteins ---- Thyroid peroxidase Source.283: DFBPPR8776 ---- Animal proteins ---- Serine/threonine-protein kinase WNK1 Source.284: DFBPPR8818 ---- Animal proteins ---- Probable ATP-dependent RNA helicase DDX4 Source.285: DFBPPR8858 ---- Animal proteins ---- Cell division cycle protein 20 homolog Source.286: DFBPPR8869 ---- Animal proteins ---- Muscarinic acetylcholine receptor M1 Source.287: DFBPPR9023 ---- Animal proteins ---- Forkhead box protein L2 Source.288: DFBPPR9024 ---- Animal proteins ---- Glutamate dehydrogenase 1, mitochondrial Source.289: DFBPPR9103 ---- Animal proteins ---- Beta-1 adrenergic receptor Source.290: DFBPPR9117 ---- Animal proteins ---- Cell cycle exit and neuronal differentiation protein 1 Source.291: DFBPPR9132 ---- Animal proteins ---- Dystrophin Source.292: DFBPPR9167 ---- Animal proteins ---- Melanocyte-stimulating hormone receptor Source.293: DFBPPR9206 ---- Animal proteins ---- Serine/threonine-protein phosphatase 1 regulatory subunit 10 Source.294: DFBPPR9237 ---- Animal proteins ---- Insulin-like growth factor-binding protein 3 Source.295: DFBPPR9371 ---- Animal proteins ---- POU domain, class 2, transcription factor 1 Source.296: DFBPPR9432 ---- Animal proteins ---- Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 Source.297: DFBPPR9513 ---- Animal proteins ---- Small conductance calcium-activated potassium channel protein 3 Source.298: DFBPPR9559 ---- Animal proteins ---- CD302 antigen Source.299: DFBPPR9586 ---- Animal proteins ---- Thrombopoietin Source.300: DFBPPR9736 ---- Animal proteins ---- Metaxin-1 Source.301: DFBPPR9773 ---- Animal proteins ---- Rab GDP dissociation inhibitor beta Source.302: DFBPPR9832 ---- Animal proteins ---- Olfactomedin-like protein 2A Source.303: DFBPPR9860 ---- Animal proteins ---- Transcription factor 19 Source.304: DFBPPR9867 ---- Animal proteins ---- Phostensin Source.305: DFBPPR9948 ---- Animal proteins ---- Vertnin Source.306: DFBPPR10004 ---- Animal proteins ---- Spastin Source.307: DFBPPR10040 ---- Animal proteins ---- Estrogen receptor Source.308: DFBPPR10050 ---- Animal proteins ---- Protocadherin-15 Source.309: DFBPPR10058 ---- Animal proteins ---- Prospero homeobox protein 1 Source.310: DFBPPR10104 ---- Animal proteins ---- Bloom syndrome protein homolog Source.311: DFBPPR10169 ---- Animal proteins ---- Proto-oncogene c-Fos Source.312: DFBPPR10180 ---- Animal proteins ---- Teneurin-2 Source.313: DFBPPR10182 ---- Animal proteins ---- Synaptotagmin-1 Source.314: DFBPPR10256 ---- Animal proteins ---- Gamma-aminobutyric acid receptor subunit alpha-6 Source.315: DFBPPR10277 ---- Animal proteins ---- Nitric oxide synthase, inducible Source.316: DFBPPR10308 ---- Animal proteins ---- DNA (cytosine-5)-methyltransferase 1 Source.317: DFBPPR10361 ---- Animal proteins ---- Protein HIRA Source.318: DFBPPR10392 ---- Animal proteins ---- Transcription factor p65 Source.319: DFBPPR10444 ---- Animal proteins ---- 5-aminolevulinate synthase, nonspecific, mitochondrial Source.320: DFBPPR10468 ---- Animal proteins ---- KH domain-containing, RNA-binding, signal transduction-associated protein 1 Source.321: DFBPPR10485 ---- Animal proteins ---- LIM domain-binding protein 1 Source.322: DFBPPR10495 ---- Animal proteins ---- Y-box-binding protein 1 Source.323: DFBPPR10518 ---- Animal proteins ---- Neural cell adhesion molecule 1 Source.324: DFBPPR10545 ---- Animal proteins ---- Transcriptional activator GLI3 Source.325: DFBPPR10771 ---- Animal proteins ---- POU domain, class 5, transcription factor 3 Source.326: DFBPPR10772 ---- Animal proteins ---- POU domain, class 5, transcription factor 3 Source.327: DFBPPR10773 ---- Animal proteins ---- POU domain, class 5, transcription factor 3 Source.328: DFBPPR10802 ---- Animal proteins ---- Kinesin-like protein KIF18B Source.329: DFBPPR10807 ---- Animal proteins ---- Dystrophin Source.330: DFBPPR10855 ---- Animal proteins ---- Transcription factor SOX-3 Source.331: DFBPPR10918 ---- Animal proteins ---- Frizzled-2 Source.332: DFBPPR10919 ---- Animal proteins ---- Ski oncogene Source.333: DFBPPR10940 ---- Animal proteins ---- Protein piccolo Source.334: DFBPPR10978 ---- Animal proteins ---- Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Source.335: DFBPPR11080 ---- Animal proteins ---- Vacuolar protein sorting-associated protein 51 homolog Source.336: DFBPPR11087 ---- Animal proteins ---- G2/mitotic-specific cyclin-B3 Source.337: DFBPPR11146 ---- Animal proteins ---- Formin Source.338: DFBPPR11163 ---- Animal proteins ---- TSC22 domain family protein 1 Source.339: DFBPPR11221 ---- Animal proteins ---- Zinc finger homeobox protein 4 Source.340: DFBPPR11258 ---- Animal proteins ---- POU domain, class 2, transcription factor 1 Source.341: DFBPPR11269 ---- Animal proteins ---- Anosmin-1 Source.342: DFBPPR11281 ---- Animal proteins ---- LIM domain-binding protein 2 Source.343: DFBPPR11300 ---- Animal proteins ---- MAM domain-containing glycosylphosphatidylinositol anchor protein 1 Source.344: DFBPPR11350 ---- Animal proteins ---- Homeobox protein Hox-D13 Source.345: DFBPPR11572 ---- Animal proteins ---- Deoxyhypusine hydroxylase Source.346: DFBPPR11607 ---- Animal proteins ---- Bromodomain adjacent to zinc finger domain protein 2B Source.347: DFBPPR11636 ---- Animal proteins ---- Epithelial splicing regulatory protein 2 Source.348: DFBPPR11704 ---- Animal proteins ---- Pre-mRNA-splicing factor SLU7 Source.349: DFBPPR11705 ---- Animal proteins ---- SCO-spondin Source.350: DFBPPR11721 ---- Animal proteins ---- Eukaryotic translation initiation factor 2A Source.351: DFBPPR11738 ---- Animal proteins ---- Ensconsin Source.352: DFBPPR11768 ---- Animal proteins ---- Homeobox protein Hox-B1 Source.353: DFBPPR11801 ---- Animal proteins ---- Homeobox protein SAX-1 Source.354: DFBPPR11807 ---- Animal proteins ---- Activating transcription factor 7-interacting protein 1 Source.355: DFBPPR11820 ---- Animal proteins ---- Lipoma-preferred partner homolog Source.356: DFBPPR11840 ---- Animal proteins ---- RELT-like protein 1 Source.357: DFBPPR11873 ---- Animal proteins ---- Ligand-dependent nuclear receptor corepressor-like protein Source.358: DFBPPR11938 ---- Animal proteins ---- Nuclear apoptosis-inducing factor 1 Source.359: DFBPPR11981 ---- Animal proteins ---- Histone deacetylase complex subunit SAP130 Source.360: DFBPPR12115 ---- Animal proteins ---- Active regulator of SIRT1 Source.361: DFBPPR12174 ---- Animal proteins ---- Protein CNPPD1 Source.362: DFBPPR12288 ---- Animal proteins ---- Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Source.363: DFBPPR12346 ---- Animal proteins ---- Adenylate cyclase type 5 Source.364: DFBPPR12371 ---- Animal proteins ---- Y-box-binding protein 1 Source.365: DFBPPR12379 ---- Animal proteins ---- Potassium voltage-gated channel subfamily KQT member 1 Source.366: DFBPPR12388 ---- Animal proteins ---- Voltage-dependent L-type calcium channel subunit alpha-1S Source.367: DFBPPR12396 ---- Animal proteins ---- Voltage-dependent P/Q-type calcium channel subunit alpha-1A Source.368: DFBPPR12430 ---- Animal proteins ---- Junctophilin-2 Source.369: DFBPPR12432 ---- Animal proteins ---- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Source.370: DFBPPR12473 ---- Animal proteins ---- Nitric oxide synthase, brain Source.371: DFBPPR12494 ---- Animal proteins ---- V(D)J recombination-activating protein 1 Source.372: DFBPPR12505 ---- Animal proteins ---- Potassium voltage-gated channel subfamily D member 3 Source.373: DFBPPR12531 ---- Animal proteins ---- Solute carrier family 12 member 4 Source.374: DFBPPR12626 ---- Animal proteins ---- E-selectin Source.375: DFBPPR12658 ---- Animal proteins ---- Tripartite motif-containing protein 72 Source.376: DFBPPR12750 ---- Animal proteins ---- Anion exchange protein 2 Source.377: DFBPPR12784 ---- Animal proteins ---- Cadherin-16 Source.378: DFBPPR12841 ---- Animal proteins ---- Forkhead box protein L2 Source.379: DFBPPR12976 ---- Animal proteins ---- Eukaryotic translation initiation factor 4 gamma 1 Source.380: DFBPPR12992 ---- Animal proteins ---- Mimecan Source.381: DFBPPR13022 ---- Animal proteins ---- Solute carrier family 13 member 2 Source.382: DFBPPR13094 ---- Animal proteins ---- Atherin Source.383: DFBPPR13315 ---- Animal proteins ---- Ski oncogene Source.384: DFBPPR13334 ---- Animal proteins ---- Anion exchange protein 2 Source.385: DFBPPR13435 ---- Animal proteins ---- Forkhead box protein L2 Source.386: DFBPPR13590 ---- Animal proteins ---- Gap junction alpha-3 protein Source.387: DFBPPR13629 ---- Animal proteins ---- Copper-transporting ATPase 2 Source.388: DFBPPR13677 ---- Animal proteins ---- Prolactin receptor Source.389: DFBPPR13719 ---- Animal proteins ---- Nitric oxide synthase, brain Source.390: DFBPPR13917 ---- Animal proteins ---- CCAAT/enhancer-binding protein delta Source.391: DFBPPR14556 ---- Marine protein ---- Interleukin-1 beta Source.392: DFBPPR14959 ---- Microorganism protein ---- Serine/threonine-protein kinase BUR1 Source.393: DFBPPR14991 ---- Microorganism protein ---- Actin cytoskeleton-regulatory complex protein PAN1 Source.394: DFBPPR15134 ---- Microorganism protein ---- Eukaryotic translation initiation factor 3 subunit A Source.395: DFBPPR15207 ---- Microorganism protein ---- Triosephosphate isomerase Source.396: DFBPPR15383 ---- Microorganism protein ---- Mediator of RNA polymerase II transcription subunit 17 Source.397: DFBPPR15709 ---- Microorganism protein ---- Increased rDNA silencing protein 4 Source.398: DFBPPR15727 ---- Microorganism protein ---- Altered inheritance of mitochondria protein 3 Source.399: DFBPPR7826 ---- Plant protein ---- U1 small nuclear ribonucleoprotein C-2 Source.400: DFBPPR7827 ---- Plant protein ---- U1 small nuclear ribonucleoprotein C-1 Source.401: DFBPPR7914 ---- Plant protein ---- CASP-like protein 1U2 Source.402: DFBPPR8234 ---- Plant protein ---- Anther-specific protein SF18
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

PEP-inhibitory activity

The peptide had almost no inhibitory activity for Prolyl endopeptidase (EC:3.4.21.26).

Table 1 PEP inhibitory activity of synthetic peptides
Peptide	IC₅₀ (μM)	K_i (μM)
APPA	> 3000	12300

Specific target protein(s)

Specific Target Protein(s):
Prolyl endopeptidase

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Bitter taste ^prediction

SMILES

N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)O

Preparation method

Mode of preparation	Chmical synthesis
Enzyme(s)/starter culture	The peptide was synthesized by the solid phase method with a 430A Peptide Synthesizer (Applied Biosystems. Inc.).

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Ohmori T, Nakagami T, Tanaka H, Maruyama S. Isolation of prolylendopeptidase-inhibiting peptides from bovine brain. Biochem Biophys Res Commun. 1994 Jul 29;202(2):809-15. PMID: 8048952 DOI: 10.1006/bbrc.1994.2002
Other literature(s)	N.D
PubDate	1994