Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPRENI0026(Renin-inhibitory peptide)

DFBP ID	DFBPRENI0026
Peptide sequence	FLLA
Type	Native peptide
Peptide/Function name	Renin-inhibitory peptide

Function-activity relationship

Main bioactivity	Renin-inhibitory activity
Otheir bioactivity	ACE-inhibitory activity ^[D1], Multifunctional activity ^[D2]

Calculated physicochemical properties

Three-letter amino acid

Phe-Leu-Leu-Ala

Single-letter amino acid

FLLA

Peptide length

Peptide mass

Experimental mass	Theoretical mass
462.62 Da	462.57 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

5.97 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

3.0500^c

Hydrophilic residue ratio

100%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Plant
Organism/Source	Common Oat (Avena sativa)
Precursor protein	11S globulin/12S globulin
Residue position	f(203–206)/f(203–206)
Precursor protein(s) search	Source.1: DFBPPR0851 ---- Plant proteins ---- Calcium-dependent protein kinase 13 Source.2: DFBPPR0951 ---- Plant proteins ---- Calpain-type cysteine protease ADL1 Source.3: DFBPPR1015 ---- Plant proteins ---- Ent-kaurene oxidase 2 Source.4: DFBPPR1016 ---- Plant proteins ---- Calcium-dependent protein kinase 12 Source.5: DFBPPR1047 ---- Plant proteins ---- Rac-like GTP-binding protein 5 Source.6: DFBPPR1141 ---- Plant proteins ---- Cysteine-rich receptor-like protein kinase 6 Source.7: DFBPPR1156 ---- Plant proteins ---- Calcium-dependent protein kinase 19 Source.8: DFBPPR1210 ---- Plant proteins ---- Pachytene checkpoint protein 2 homolog Source.9: DFBPPR1288 ---- Plant proteins ---- Calcium-dependent protein kinase 5 Source.10: DFBPPR1310 ---- Plant proteins ---- Rac-like GTP-binding protein 6 Source.11: DFBPPR1333 ---- Plant proteins ---- Endoglucanase 2 Source.12: DFBPPR1400 ---- Plant proteins ---- Cellulose synthase-like protein D4 Source.13: DFBPPR1415 ---- Plant proteins ---- Rac-like GTP-binding protein 7 Source.14: DFBPPR1627 ---- Plant proteins ---- Probable histidine kinase 5 Source.15: DFBPPR1644 ---- Plant proteins ---- Phosphoenolpyruvate/phosphate translocator 1, chloroplastic Source.16: DFBPPR1692 ---- Plant proteins ---- Phosphoenolpyruvate/phosphate translocator 2, chloroplastic Source.17: DFBPPR1702 ---- Plant proteins ---- Glutelin type-A 2 Source.18: DFBPPR1806 ---- Plant proteins ---- Laccase-19 Source.19: DFBPPR1835 ---- Plant proteins ---- Laccase-15 Source.20: DFBPPR1842 ---- Plant proteins ---- 2-oxoglutarate-dependent dioxygenase DAO Source.21: DFBPPR1870 ---- Plant proteins ---- Laccase-20 Source.22: DFBPPR1874 ---- Plant proteins ---- Inorganic phosphate transporter 1-6 Source.23: DFBPPR1884 ---- Plant proteins ---- Putative laccase-1 Source.24: DFBPPR2000 ---- Plant proteins ---- Sodium/calcium exchanger NCL1 Source.25: DFBPPR2035 ---- Plant proteins ---- Glutelin type-A 1 Source.26: DFBPPR2078 ---- Plant proteins ---- Two pore potassium channel c Source.27: DFBPPR2089 ---- Plant proteins ---- ATP-dependent zinc metalloprotease FTSH 3, mitochondrial Source.28: DFBPPR2126 ---- Plant proteins ---- Glutelin type-B 2 Source.29: DFBPPR2275 ---- Plant proteins ---- Acyl-CoA-binding domain-containing protein 5 Source.30: DFBPPR2277 ---- Plant proteins ---- Protein TOC75, chloroplastic Source.31: DFBPPR2302 ---- Plant proteins ---- Bowman-Birk type bran trypsin inhibitor Source.32: DFBPPR2323 ---- Plant proteins ---- Ent-kaurene oxidase-like 3 Source.33: DFBPPR2336 ---- Plant proteins ---- Protein arginine N-methyltransferase 5 Source.34: DFBPPR2461 ---- Plant proteins ---- Glutelin type-B 1 Source.35: DFBPPR2468 ---- Plant proteins ---- Germin-like protein 8-3 Source.36: DFBPPR2483 ---- Plant proteins ---- P-loop NTPase domain-containing protein LPA1 Source.37: DFBPPR2499 ---- Plant proteins ---- Probable glucomannan 4-beta-mannosyltransferase 5 Source.38: DFBPPR2503 ---- Plant proteins ---- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1A Source.39: DFBPPR2522 ---- Plant proteins ---- Puromycin-sensitive aminopeptidase Source.40: DFBPPR2526 ---- Plant proteins ---- Chitinase 10 Source.41: DFBPPR2571 ---- Plant proteins ---- Protochlorophyllide reductase B, chloroplastic Source.42: DFBPPR2647 ---- Plant proteins ---- Silicon efflux transporter LSI2 Source.43: DFBPPR2688 ---- Plant proteins ---- Regulatory-associated protein of TOR 2 Source.44: DFBPPR2716 ---- Plant proteins ---- Endoglucanase 1 Source.45: DFBPPR2753 ---- Plant proteins ---- Transportin-1 Source.46: DFBPPR2759 ---- Plant proteins ---- Probable cytokinin riboside 5'-monophosphate phosphoribohydrolase LOGL9 Source.47: DFBPPR2765 ---- Plant proteins ---- Regulatory-associated protein of TOR 1 Source.48: DFBPPR2829 ---- Plant proteins ---- CDP-diacylglycerol--serine O-phosphatidyltransferase 2 Source.49: DFBPPR2839 ---- Plant proteins ---- Multicopper oxidase LPR1 homolog 2 Source.50: DFBPPR2854 ---- Plant proteins ---- ABC transporter G family member 34 Source.51: DFBPPR2914 ---- Plant proteins ---- Glutelin type-D 1 Source.52: DFBPPR2920 ---- Plant proteins ---- Putative germin-like protein 2-3 Source.53: DFBPPR2936 ---- Plant proteins ---- Putative germin-like protein 2-1 Source.54: DFBPPR3064 ---- Plant proteins ---- Probable metal-nicotianamine transporter YSL9 Source.55: DFBPPR3096 ---- Plant proteins ---- Protochlorophyllide reductase A, chloroplastic Source.56: DFBPPR3154 ---- Plant proteins ---- Endoglucanase 7 Source.57: DFBPPR3322 ---- Plant proteins ---- Putative xyloglucan glycosyltransferase 10 Source.58: DFBPPR3358 ---- Plant proteins ---- Glutelin type-B 4 Source.59: DFBPPR3362 ---- Plant proteins ---- Probable alpha-glucosidase Os06g0675700 Source.60: DFBPPR3377 ---- Plant proteins ---- Endoglucanase 3 Source.61: DFBPPR3410 ---- Plant proteins ---- Probable inorganic phosphate transporter 1-5 Source.62: DFBPPR3505 ---- Plant proteins ---- Ribosome biogenesis protein WDR12 homolog Source.63: DFBPPR3565 ---- Plant proteins ---- Photosystem II reaction center protein K Source.64: DFBPPR3666 ---- Plant proteins ---- Glutelin type-B 5 Source.65: DFBPPR3764 ---- Plant proteins ---- Cytochrome b6-f complex subunit 6 Source.66: DFBPPR3864 ---- Plant proteins ---- Probable sodium/metabolite cotransporter BASS2, chloroplastic Source.67: DFBPPR3985 ---- Plant proteins ---- 4-coumarate--CoA ligase-like 2 Source.68: DFBPPR4038 ---- Plant proteins ---- Probable metal-nicotianamine transporter YSL8 Source.69: DFBPPR4039 ---- Plant proteins ---- Silicon efflux transporter LSI3 Source.70: DFBPPR4256 ---- Plant proteins ---- Copper transporter 4 Source.71: DFBPPR4268 ---- Plant proteins ---- Copper transporter 6 Source.72: DFBPPR4274 ---- Plant proteins ---- Tubby-like F-box protein 6 Source.73: DFBPPR4410 ---- Plant proteins ---- Zinc finger CCCH domain-containing protein 53 Source.74: DFBPPR4478 ---- Plant proteins ---- Ammonium transporter 3 member 1 Source.75: DFBPPR4489 ---- Plant proteins ---- Protein NLP1 Source.76: DFBPPR4534 ---- Plant proteins ---- Protein argonaute 4A Source.77: DFBPPR4545 ---- Plant proteins ---- Tubby-like F-box protein 12 Source.78: DFBPPR4563 ---- Plant proteins ---- CASP-like protein 4C1 Source.79: DFBPPR4595 ---- Plant proteins ---- Tubby-like F-box protein 9 Source.80: DFBPPR4603 ---- Plant proteins ---- Tubby-like F-box protein 2 Source.81: DFBPPR4661 ---- Plant proteins ---- Protein argonaute 4B Source.82: DFBPPR4717 ---- Plant proteins ---- Tubby-like F-box protein 11 Source.83: DFBPPR4849 ---- Plant proteins ---- Putative ripening-related protein 5 Source.84: DFBPPR5079 ---- Plant proteins ---- Albumin-1 Source.85: DFBPPR5128 ---- Plant proteins ---- Elongation factor Tu, chloroplastic Source.86: DFBPPR5138 ---- Plant proteins ---- Subtilisin-like protease Glyma18g48580 Source.87: DFBPPR5139 ---- Plant proteins ---- ATP-dependent Clp protease proteolytic subunit Source.88: DFBPPR5155 ---- Plant proteins ---- Elongation factor Tu, chloroplastic Source.89: DFBPPR5171 ---- Plant proteins ---- Sucrose-binding protein Source.90: DFBPPR5277 ---- Plant proteins ---- Cytochrome P450 97B2, chloroplastic Source.91: DFBPPR5281 ---- Plant proteins ---- Photosystem II reaction center protein K Source.92: DFBPPR5387 ---- Plant proteins ---- Calpain-type cysteine protease DEK1 Source.93: DFBPPR5524 ---- Plant proteins ---- Calcium-dependent protein kinase 2 Source.94: DFBPPR5527 ---- Plant proteins ---- Exopolygalacturonase Source.95: DFBPPR5685 ---- Plant proteins ---- Protein ABERRANT POLLEN TRANSMISSION 1 Source.96: DFBPPR5804 ---- Plant proteins ---- L-lactate dehydrogenase Source.97: DFBPPR5814 ---- Plant proteins ---- NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic Source.98: DFBPPR5958 ---- Plant proteins ---- Cytochrome c oxidase subunit 3 Source.99: DFBPPR5967 ---- Plant proteins ---- Cytochrome b6-f complex subunit 6 Source.100: DFBPPR6007 ---- Plant proteins ---- Photosystem II reaction center protein K Source.101: DFBPPR6313 ---- Plant proteins ---- Elongation factor Tu, chloroplastic Source.102: DFBPPR6484 ---- Plant proteins ---- Cytochrome P450 97B1, chloroplastic Source.103: DFBPPR6531 ---- Plant proteins ---- 2-dehydro-3-deoxyphosphooctonate aldolase Source.104: DFBPPR6561 ---- Plant proteins ---- Blue copper protein Source.105: DFBPPR6640 ---- Plant proteins ---- Puroindoline-B Source.106: DFBPPR6731 ---- Plant proteins ---- Plasma membrane ATPase Source.107: DFBPPR6792 ---- Plant proteins ---- Cytochrome b6-f complex subunit 6 Source.108: DFBPPR6814 ---- Plant proteins ---- Protochlorophyllide reductase A, chloroplastic Source.109: DFBPPR6831 ---- Plant proteins ---- NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic Source.110: DFBPPR6854 ---- Plant proteins ---- Eukaryotic translation initiation factor 2 subunit beta Source.111: DFBPPR6906 ---- Plant proteins ---- Photosystem II reaction center protein K Source.112: DFBPPR6923 ---- Plant proteins ---- Avenin-like a1 Source.113: DFBPPR6961 ---- Plant proteins ---- Avenin-like a2 Source.114: DFBPPR6964 ---- Plant proteins ---- Avenin-like a3 Source.115: DFBPPR7032 ---- Plant proteins ---- Hordoindoline-B2 Source.116: DFBPPR7069 ---- Plant proteins ---- Hordoindoline-B1 Source.117: DFBPPR7119 ---- Plant proteins ---- Protochlorophyllide reductase A, chloroplastic Source.118: DFBPPR7138 ---- Plant proteins ---- Protochlorophyllide reductase B, chloroplastic Source.119: DFBPPR7187 ---- Plant proteins ---- NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic Source.120: DFBPPR7218 ---- Plant proteins ---- Photosystem II reaction center protein K Source.121: DFBPPR7256 ---- Plant proteins ---- Cytochrome b6-f complex subunit 6 Source.122: DFBPPR7400 ---- Plant proteins ---- Myrosinase Source.123: DFBPPR7416 ---- Plant proteins ---- Cruciferin CRU4 Source.124: DFBPPR7517 ---- Plant proteins ---- Uncharacterized mitochondrial protein ORF138 Source.125: DFBPPR7600 ---- Milk proteins ---- UDP-glucuronosyltransferase 1A1 Source.126: DFBPPR7635 ---- Milk proteins ---- Prosaposin Source.127: DFBPPR7733 ---- Plant proteins ---- 12S seed storage globulin 2 Source.128: DFBPPR7734 ---- Plant proteins ---- 12S seed storage globulin 1 Source.129: DFBPPR7740 ---- Plant proteins ---- Protochlorophyllide reductase Source.130: DFBPPR7746 ---- Plant proteins ---- Thaumatin-like pathogenesis-related protein 2 Source.131: DFBPPR8381 ---- Plant proteins ---- Conglutin-7 Source.132: DFBPPR8428 ---- Plant proteins ---- 11S globulin seed storage protein 2 Source.133: DFBPPR8472 ---- Plant proteins ---- Photosystem II reaction center protein K Source.134: DFBPPR15947 ---- Animal proteins ---- Beta-2 adrenergic receptor Source.135: DFBPPR15953 ---- Animal proteins ---- Occludin Source.136: DFBPPR15991 ---- Animal proteins ---- Toll-like receptor 9 Source.137: DFBPPR15993 ---- Animal proteins ---- Sodium/myo-inositol cotransporter Source.138: DFBPPR16097 ---- Animal proteins ---- Thyrotropin receptor Source.139: DFBPPR16108 ---- Animal proteins ---- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 Source.140: DFBPPR16114 ---- Animal proteins ---- Collagen alpha-5(IV) chain Source.141: DFBPPR16138 ---- Animal proteins ---- Claudin-3 Source.142: DFBPPR16205 ---- Animal proteins ---- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 Source.143: DFBPPR16208 ---- Animal proteins ---- Ammonium transporter Rh type B Source.144: DFBPPR16269 ---- Animal proteins ---- Ammonium transporter Rh type C Source.145: DFBPPR16445 ---- Animal proteins ---- Pancreatic secretory granule membrane major glycoprotein GP2 Source.146: DFBPPR16561 ---- Animal proteins ---- UDP-glucuronosyltransferase 2B31 Source.147: DFBPPR16705 ---- Animal proteins ---- G2/mitotic-specific cyclin-B3 Source.148: DFBPPR16736 ---- Animal proteins ---- WD repeat-containing protein 46 Source.149: DFBPPR16879 ---- Animal proteins ---- Inhibin beta A chain Source.150: DFBPPR17003 ---- Animal proteins ---- Toll-like receptor 9 Source.151: DFBPPR17029 ---- Animal proteins ---- Cytochrome b-245 light chain Source.152: DFBPPR17122 ---- Animal proteins ---- Glycine receptor subunit beta Source.153: DFBPPR17142 ---- Animal proteins ---- Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Source.154: DFBPPR17164 ---- Animal proteins ---- Beta-2 adrenergic receptor Source.155: DFBPPR17195 ---- Animal proteins ---- Receptor for retinol uptake STRA6 Source.156: DFBPPR17205 ---- Animal proteins ---- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial Source.157: DFBPPR17207 ---- Animal proteins ---- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial Source.158: DFBPPR17277 ---- Animal proteins ---- Serpin A3-1 Source.159: DFBPPR17444 ---- Animal proteins ---- Adhesion G protein-coupled receptor L1 Source.160: DFBPPR17543 ---- Animal proteins ---- 4-hydroxy-2-oxoglutarate aldolase, mitochondrial Source.161: DFBPPR17550 ---- Animal proteins ---- Serine/threonine-protein kinase PLK4 Source.162: DFBPPR17571 ---- Animal proteins ---- Proton-coupled folate transporter Source.163: DFBPPR17582 ---- Animal proteins ---- Ferroptosis suppressor protein 1 Source.164: DFBPPR17592 ---- Animal proteins ---- Claudin-3 Source.165: DFBPPR17593 ---- Animal proteins ---- Claudin-3 Source.166: DFBPPR17804 ---- Animal proteins ---- Calpain-1 catalytic subunit Source.167: DFBPPR17825 ---- Animal proteins ---- Thyrotropin receptor Source.168: DFBPPR17984 ---- Animal proteins ---- Phosphatidylinositol 3-kinase regulatory subunit beta Source.169: DFBPPR18077 ---- Animal proteins ---- Gastric triacylglycerol lipase Source.170: DFBPPR18085 ---- Animal proteins ---- Staphylococcal nuclease domain-containing protein 1 Source.171: DFBPPR18209 ---- Animal proteins ---- Sodium-dependent noradrenaline transporter Source.172: DFBPPR18307 ---- Animal proteins ---- Claudin-4 Source.173: DFBPPR18406 ---- Animal proteins ---- Angiotensinogen Source.174: DFBPPR18494 ---- Animal proteins ---- Prostacyclin receptor Source.175: DFBPPR18573 ---- Animal proteins ---- T-cell surface glycoprotein CD3 gamma chain Source.176: DFBPPR18628 ---- Animal proteins ---- Cytochrome b5 reductase 4 Source.177: DFBPPR18824 ---- Animal proteins ---- Hydroxymethylglutaryl-CoA synthase, mitochondrial Source.178: DFBPPR18974 ---- Animal proteins ---- Adrenocorticotropic hormone receptor Source.179: DFBPPR19020 ---- Animal proteins ---- Ammonium transporter Rh type B Source.180: DFBPPR19038 ---- Animal proteins ---- Short transient receptor potential channel 1 Source.181: DFBPPR19053 ---- Animal proteins ---- Transmembrane protein 100 Source.182: DFBPPR19222 ---- Animal proteins ---- Interferon alpha-H Source.183: DFBPPR19281 ---- Animal proteins ---- Sorting nexin-1 Source.184: DFBPPR19338 ---- Animal proteins ---- Solute carrier family 22 member 6 Source.185: DFBPPR19394 ---- Animal proteins ---- Solute carrier family 10 member 6 Source.186: DFBPPR19434 ---- Animal proteins ---- Interferon alpha-B Source.187: DFBPPR19475 ---- Animal proteins ---- Coronin-7 Source.188: DFBPPR19572 ---- Animal proteins ---- Pentatricopeptide repeat domain-containing protein 3, mitochondrial Source.189: DFBPPR19581 ---- Animal proteins ---- Leucine zipper putative tumor suppressor 2 Source.190: DFBPPR19589 ---- Animal proteins ---- 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Source.191: DFBPPR19612 ---- Animal proteins ---- Lysosomal-trafficking regulator Source.192: DFBPPR19615 ---- Animal proteins ---- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 Source.193: DFBPPR19643 ---- Animal proteins ---- Chromodomain-helicase-DNA-binding protein 1-like Source.194: DFBPPR19697 ---- Animal proteins ---- Sodium/myo-inositol cotransporter Source.195: DFBPPR19823 ---- Animal proteins ---- Alanine aminotransferase 1 Source.196: DFBPPR19872 ---- Animal proteins ---- Glucose-6-phosphatase 3 Source.197: DFBPPR20012 ---- Animal proteins ---- Zinc transporter ZIP12 Source.198: DFBPPR20058 ---- Animal proteins ---- Eukaryotic translation initiation factor 2 subunit 2 Source.199: DFBPPR20431 ---- Animal proteins ---- Cell division cycle protein 27 homolog Source.200: DFBPPR20594 ---- Animal proteins ---- Vitamin D-binding protein Source.201: DFBPPR20626 ---- Animal proteins ---- Melanocortin receptor 5 Source.202: DFBPPR20636 ---- Animal proteins ---- Transforming growth factor-beta receptor-associated protein 1 Source.203: DFBPPR20745 ---- Animal proteins ---- ETS-related transcription factor Elf-1 Source.204: DFBPPR20804 ---- Animal proteins ---- N-acetyl-D-glucosamine kinase Source.205: DFBPPR20806 ---- Animal proteins ---- Transcriptional adapter 1 Source.206: DFBPPR20808 ---- Animal proteins ---- Monocarboxylate transporter 13 Source.207: DFBPPR20895 ---- Animal proteins ---- Solute carrier family 22 member 16 Source.208: DFBPPR21018 ---- Animal proteins ---- Solute carrier family 22 member 17 Source.209: DFBPPR21160 ---- Animal proteins ---- Prefoldin subunit 3 Source.210: DFBPPR21247 ---- Animal proteins ---- Serpin A3-5 Source.211: DFBPPR21287 ---- Animal proteins ---- Serpin A3-2 Source.212: DFBPPR21477 ---- Animal proteins ---- Protein phosphatase 1 regulatory subunit 35 Source.213: DFBPPR21486 ---- Animal proteins ---- Caspase recruitment domain-containing protein 19 Source.214: DFBPPR21498 ---- Animal proteins ---- Alanyl-tRNA editing protein Aarsd1 Source.215: DFBPPR21504 ---- Animal proteins ---- Ribonuclease P protein subunit p40 Source.216: DFBPPR21653 ---- Animal proteins ---- Cytochrome P450 20A1 Source.217: DFBPPR21735 ---- Animal proteins ---- Serpin A3-7 Source.218: DFBPPR22340 ---- Animal proteins ---- Lysoplasmalogenase-like protein TMEM86A Source.219: DFBPPR8560 ---- Animal proteins ---- Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Source.220: DFBPPR8616 ---- Animal proteins ---- Pleiotrophin Source.221: DFBPPR8628 ---- Animal proteins ---- Inhibin beta A chain Source.222: DFBPPR8650 ---- Animal proteins ---- Beta-2 adrenergic receptor Source.223: DFBPPR8681 ---- Animal proteins ---- Toll-like receptor 9 Source.224: DFBPPR8775 ---- Animal proteins ---- Formimidoyltransferase-cyclodeaminase Source.225: DFBPPR9140 ---- Animal proteins ---- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 Source.226: DFBPPR9165 ---- Animal proteins ---- Solute carrier family 22 member 2 Source.227: DFBPPR9209 ---- Animal proteins ---- Cytochrome b-245 light chain Source.228: DFBPPR9224 ---- Animal proteins ---- Solute carrier family 22 member 6 Source.229: DFBPPR9259 ---- Animal proteins ---- Sodium/glucose cotransporter 1 Source.230: DFBPPR9322 ---- Animal proteins ---- Solute carrier family 5 member 4 Source.231: DFBPPR9332 ---- Animal proteins ---- B2 bradykinin receptor Source.232: DFBPPR9337 ---- Animal proteins ---- Adrenocorticotropic hormone receptor Source.233: DFBPPR9358 ---- Animal proteins ---- Hydroxymethylglutaryl-CoA synthase, mitochondrial Source.234: DFBPPR9378 ---- Animal proteins ---- Ammonium transporter Rh type C Source.235: DFBPPR9399 ---- Animal proteins ---- High affinity copper uptake protein 1 Source.236: DFBPPR9446 ---- Animal proteins ---- Ammonium transporter Rh type B Source.237: DFBPPR9496 ---- Animal proteins ---- C-X-C motif chemokine 16 Source.238: DFBPPR9548 ---- Animal proteins ---- Membrane progestin receptor alpha Source.239: DFBPPR9648 ---- Animal proteins ---- Secretogranin-2 Source.240: DFBPPR10192 ---- Animal proteins ---- Vascular endothelial growth factor receptor 1 Source.241: DFBPPR10512 ---- Animal proteins ---- Collagen alpha-1(XIV) chain Source.242: DFBPPR10524 ---- Animal proteins ---- Protein disulfide-isomerase Source.243: DFBPPR10525 ---- Animal proteins ---- Thyroid hormone receptor beta Source.244: DFBPPR10538 ---- Animal proteins ---- Retinoblastoma-associated protein Source.245: DFBPPR10561 ---- Animal proteins ---- Lens fiber major intrinsic protein Source.246: DFBPPR10580 ---- Animal proteins ---- Creatine kinase U-type, mitochondrial Source.247: DFBPPR10581 ---- Animal proteins ---- Ephrin-A5 Source.248: DFBPPR10690 ---- Animal proteins ---- V(D)J recombination-activating protein 1 Source.249: DFBPPR10750 ---- Animal proteins ---- Phosphatidylserine synthase 2 Source.250: DFBPPR10847 ---- Animal proteins ---- Protein patched homolog 1 Source.251: DFBPPR10918 ---- Animal proteins ---- Frizzled-2 Source.252: DFBPPR10927 ---- Animal proteins ---- Frizzled-7 Source.253: DFBPPR10933 ---- Animal proteins ---- DNA cross-link repair 1A protein Source.254: DFBPPR11003 ---- Animal proteins ---- Acetylcholine receptor subunit gamma Source.255: DFBPPR11079 ---- Animal proteins ---- Frizzled-1 Source.256: DFBPPR11234 ---- Animal proteins ---- Bleomycin hydrolase Source.257: DFBPPR11294 ---- Animal proteins ---- Frizzled-8 Source.258: DFBPPR11622 ---- Animal proteins ---- Ammonium transporter Rh type C Source.259: DFBPPR11645 ---- Animal proteins ---- NADH-ubiquinone oxidoreductase chain 1 Source.260: DFBPPR11720 ---- Animal proteins ---- Interleukin-17 receptor D Source.261: DFBPPR11955 ---- Animal proteins ---- Solute carrier family 41 member 2 Source.262: DFBPPR11971 ---- Animal proteins ---- Protein YIPF4 Source.263: DFBPPR11998 ---- Animal proteins ---- Kelch-like protein 15 Source.264: DFBPPR12039 ---- Animal proteins ---- Protein GOLM2 Source.265: DFBPPR12084 ---- Animal proteins ---- EF-hand domain-containing family member C2 Source.266: DFBPPR12146 ---- Animal proteins ---- Transmembrane protein adipocyte-associated 1 homolog Source.267: DFBPPR12295 ---- Animal proteins ---- Sodium/hydrogen exchanger 3 Source.268: DFBPPR12306 ---- Animal proteins ---- Sodium/glucose cotransporter 1 Source.269: DFBPPR12494 ---- Animal proteins ---- V(D)J recombination-activating protein 1 Source.270: DFBPPR12580 ---- Animal proteins ---- Eukaryotic translation initiation factor 2 subunit 2 Source.271: DFBPPR12641 ---- Animal proteins ---- Cytochrome b-245 light chain Source.272: DFBPPR12729 ---- Animal proteins ---- Solute carrier family 22 member 2 Source.273: DFBPPR12765 ---- Animal proteins ---- Chloride transport protein 6 Source.274: DFBPPR12789 ---- Animal proteins ---- CD59 glycoprotein Source.275: DFBPPR12808 ---- Animal proteins ---- UDP-glucuronosyltransferase 1-6 Source.276: DFBPPR12834 ---- Animal proteins ---- B1 bradykinin receptor Source.277: DFBPPR12851 ---- Animal proteins ---- UDP-glucuronosyltransferase 1A4 Source.278: DFBPPR12895 ---- Animal proteins ---- UDP-glucuronosyltransferase 2B16 Source.279: DFBPPR12900 ---- Animal proteins ---- Solute carrier family 22 member 6 Source.280: DFBPPR12904 ---- Animal proteins ---- UDP-glucuronosyltransferase 2B13 Source.281: DFBPPR12942 ---- Animal proteins ---- Ammonium transporter Rh type C Source.282: DFBPPR12958 ---- Animal proteins ---- Neuromedin-K receptor Source.283: DFBPPR12967 ---- Animal proteins ---- Beta-sarcoglycan Source.284: DFBPPR12999 ---- Animal proteins ---- Short transient receptor potential channel 1 Source.285: DFBPPR13143 ---- Animal proteins ---- Toll-like receptor 9 Source.286: DFBPPR13157 ---- Animal proteins ---- Inhibin beta A chain Source.287: DFBPPR13209 ---- Animal proteins ---- Parathyroid hormone Source.288: DFBPPR13552 ---- Animal proteins ---- Inhibin beta A chain Source.289: DFBPPR13576 ---- Animal proteins ---- Toll-like receptor 9 Source.290: DFBPPR13612 ---- Animal proteins ---- Thyrotropin receptor Source.291: DFBPPR13624 ---- Animal proteins ---- Sodium/glucose cotransporter 1 Source.292: DFBPPR13680 ---- Animal proteins ---- Interferon alpha/beta receptor 2 Source.293: DFBPPR13690 ---- Animal proteins ---- Angiotensinogen Source.294: DFBPPR13725 ---- Animal proteins ---- T-cell surface glycoprotein CD3 gamma chain Source.295: DFBPPR13735 ---- Animal proteins ---- Thyroid hormone receptor beta Source.296: DFBPPR13823 ---- Animal proteins ---- Adrenocorticotropic hormone receptor Source.297: DFBPPR13892 ---- Animal proteins ---- Melanocortin receptor 5 Source.298: DFBPPR13901 ---- Animal proteins ---- NADH-ubiquinone oxidoreductase chain 3 Source.299: DFBPPR13993 ---- Animal proteins ---- Insulin Source.300: DFBPPR14204 ---- Marine protein ---- Riboflavin transporter 2 Source.301: DFBPPR14376 ---- Marine protein ---- ATP synthase subunit b', chloroplastic Source.302: DFBPPR14479 ---- Marine protein ---- Photosystem I assembly protein Ycf4 Source.303: DFBPPR14572 ---- Marine protein ---- V(D)J recombination-activating protein 1 Source.304: DFBPPR15029 ---- Microorganism protein ---- Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase Source.305: DFBPPR15342 ---- Microorganism protein ---- Histone transcription regulator 3 homolog Source.306: DFBPPR15394 ---- Microorganism protein ---- 1,4-alpha-glucan-branching enzyme Source.307: DFBPPR15483 ---- Microorganism protein ---- Elongation factor 2 Source.308: DFBPPR7787 ---- Plant protein ---- Fatty acid desaturase DES3 Source.309: DFBPPR7796 ---- Plant protein ---- NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic Source.310: DFBPPR7854 ---- Plant protein ---- Cytochrome b6-f complex subunit 6 Source.311: DFBPPR7866 ---- Plant protein ---- Photosystem II reaction center protein K Source.312: DFBPPR8099 ---- Plant protein ---- ATP-dependent Clp protease proteolytic subunit Source.313: DFBPPR8117 ---- Plant protein ---- Cytochrome b6-f complex subunit 6 Source.314: DFBPPR8301 ---- Plant protein ---- Photosystem II reaction center protein K
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

Renin-inhibitory activity	When tested at a concentration of 1 mg / mL, the inhibitory power of FLLA to inhibit Renin (EC:3.4.23.15) was found to be approximately 7% (very weak).
Specific target protein(s)	Specific Target Protein(s): Renin

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Bitter taste ^prediction

SMILES

N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)O

Preparation method

Mode of preparation	Enzymatic hydrolysis
Enzyme(s)/starter culture	Renin inhibition assay of several chemically synthesised peptides from predicted oat protein protein hydrolysates following in silico digestion with the proteases papain and ficin.

Stability & Cytotoxicity

Peptide stability

Literature report:

Peptide	Solubility in Water	Resistance to Digestion	Allergenicity Probability
FLLA	Poor	No	Non-allergen

EHP-Tool:

Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	Non-Toxin
Prediction:	ToxinPred

Additional information

N.D

Database cross-references

DFBP

[D1]	DFBPACEI1964
[D2]	DFBPMUFU0591

[D3]

[D4]

[D5]

[D6]

Reference(s)

Primary literature	Bleakley S, Hayes M, O' Shea N, Gallagher E, Lafarga T. Predicted Release and Analysis of Novel ACE-I, Renin, and DPP-IV Inhibitory Peptides from Common Oat (Avena sativa) Protein Hydrolysates Using in Silico Analysis. Foods. 2017 Dec 4;6(12):108. PMID: 29207547 DOI: 10.3390/foods6120108
Other literature(s)	N.D
PubDate	2017