Peptide properties

1Top 2Function-activity relationship 3Calculated physicochemical properties 4Peptide source & Food-borne protein(s) search 5Biological/Functional activity & target protein 6Taste properties & Structure 7Preparation method 8Stability & Cytotoxicity 9Additional information 10Database cross-references 11Reference(s)

List of peptide properties

DFBP ID - DFBPANTH0098(Antithrombotic peptide)

DFBP ID	DFBPANTH0098
Peptide sequence	HCF
Type	Native peptide
Peptide/Function name	Antithrombotic peptide

Function-activity relationship

Main bioactivity	Antithrombotic activity
Otheir bioactivity	N.D

Calculated physicochemical properties

Three-letter amino acid

His-Cys-Phe

Single-letter amino acid

HCF

Peptide length

Peptide mass

Experimental mass	Theoretical mass
408 Da	405.48 Da ^c

Net charge

0.00 ^c

Isoelectric point (pI)

7.14 ^c

IC₅₀

N.D

pIC₅₀

N.D

GRAVY

0.7000^c

Hydrophilic residue ratio

33.33%^c

Peptide calculator

Peptide source & Food-borne protein(s) search

Classification	Marine
Organism/Source	Goby mussel (Zosterisessor ophiocephalus)
Precursor protein	Muscle proteins
Residue position	N.D
Precursor protein(s) search	Source.1: DFBPPR0903 ---- Plant proteins ---- Shaggy-related protein kinase GSK2 Source.2: DFBPPR0913 ---- Plant proteins ---- Endoribonuclease Dicer homolog 4 Source.3: DFBPPR0929 ---- Plant proteins ---- Protein ROS1A Source.4: DFBPPR0999 ---- Plant proteins ---- Shaggy-related protein kinase GSK1 Source.5: DFBPPR1064 ---- Plant proteins ---- Probable histidine kinase 6 Source.6: DFBPPR1152 ---- Plant proteins ---- Cytochrome P450 703A2 Source.7: DFBPPR1226 ---- Plant proteins ---- Acetylserotonin O-methyltransferase 3 Source.8: DFBPPR1295 ---- Plant proteins ---- Ferredoxin--NADP reductase, leaf isozyme 1, chloroplastic Source.9: DFBPPR1331 ---- Plant proteins ---- Peroxidase 1 Source.10: DFBPPR1362 ---- Plant proteins ---- Protein ROS1C Source.11: DFBPPR1388 ---- Plant proteins ---- Acetylserotonin O-methyltransferase 2 Source.12: DFBPPR1487 ---- Plant proteins ---- Beta-1,2-xylosyltransferease XAX1 Source.13: DFBPPR1559 ---- Plant proteins ---- Probable kinase CHARK Source.14: DFBPPR1753 ---- Plant proteins ---- Protein TPR3 Source.15: DFBPPR1810 ---- Plant proteins ---- Shaggy-related protein kinase GSK4 Source.16: DFBPPR2136 ---- Plant proteins ---- Alpha-1,3-arabinosyltransferase XAT3 Source.17: DFBPPR2169 ---- Plant proteins ---- Alpha-1,3-arabinosyltransferase XAT2 Source.18: DFBPPR2607 ---- Plant proteins ---- S-adenosylmethionine decarboxylase proenzyme Source.19: DFBPPR2669 ---- Plant proteins ---- Arginine decarboxylase 1 Source.20: DFBPPR2812 ---- Plant proteins ---- Lysine-specific histone demethylase 1 homolog 1 Source.21: DFBPPR2995 ---- Plant proteins ---- Eukaryotic translation initiation factor 4E-1 Source.22: DFBPPR3601 ---- Plant proteins ---- Growth-regulating factor 1 Source.23: DFBPPR3819 ---- Plant proteins ---- Patatin-like protein 1 Source.24: DFBPPR3820 ---- Plant proteins ---- Probable monogalactosyldiacylglycerol synthase 3, chloroplastic Source.25: DFBPPR3889 ---- Plant proteins ---- Lysine-specific histone demethylase 1 homolog 2 Source.26: DFBPPR3942 ---- Plant proteins ---- Lysine-specific histone demethylase 1 homolog 3 Source.27: DFBPPR4040 ---- Plant proteins ---- Potassium channel KAT3 Source.28: DFBPPR4103 ---- Plant proteins ---- Probable serine acetyltransferase 4 Source.29: DFBPPR4197 ---- Plant proteins ---- Probable serine acetyltransferase 3 Source.30: DFBPPR4261 ---- Plant proteins ---- Zinc finger CCCH domain-containing protein 16 Source.31: DFBPPR4349 ---- Plant proteins ---- Pentatricopeptide repeat-containing protein PPR5 homolog, chloroplastic Source.32: DFBPPR4359 ---- Plant proteins ---- Protein STAY-GREEN LIKE, chloroplastic Source.33: DFBPPR4377 ---- Plant proteins ---- Trafficking protein particle complex II-specific subunit 120 homolog Source.34: DFBPPR4480 ---- Plant proteins ---- Formin-like protein 7 Source.35: DFBPPR4595 ---- Plant proteins ---- Tubby-like F-box protein 9 Source.36: DFBPPR4617 ---- Plant proteins ---- Probable cleavage and polyadenylation specificity factor subunit 1 Source.37: DFBPPR4700 ---- Plant proteins ---- Protein DEHYDRATION-INDUCED 19 homolog 6 Source.38: DFBPPR4837 ---- Plant proteins ---- Protein DEHYDRATION-INDUCED 19 homolog 5 Source.39: DFBPPR4977 ---- Plant proteins ---- Leucine-rich repeat receptor-like kinase protein CLV1B Source.40: DFBPPR5013 ---- Plant proteins ---- Leucine-rich repeat receptor-like kinase protein CLV1a Source.41: DFBPPR5161 ---- Plant proteins ---- Omega-6 fatty acid desaturase, endoplasmic reticulum isozyme 1 Source.42: DFBPPR5184 ---- Plant proteins ---- Omega-6 fatty acid desaturase, endoplasmic reticulum isozyme 2 Source.43: DFBPPR5446 ---- Plant proteins ---- Protein OPAQUE1 Source.44: DFBPPR5519 ---- Plant proteins ---- Beta-selinene synthase Source.45: DFBPPR5599 ---- Plant proteins ---- Pentatricopeptide repeat-containing protein PPR5, chloroplastic Source.46: DFBPPR5718 ---- Plant proteins ---- NADP-dependent glyceraldehyde-3-phosphate dehydrogenase Source.47: DFBPPR5772 ---- Plant proteins ---- Eukaryotic translation initiation factor 4E-1 Source.48: DFBPPR5811 ---- Plant proteins ---- ATP synthase subunit a Source.49: DFBPPR5849 ---- Plant proteins ---- S-adenosylmethionine decarboxylase proenzyme Source.50: DFBPPR6019 ---- Plant proteins ---- Inactive beta selinene synthase Source.51: DFBPPR6260 ---- Plant proteins ---- Delta(24)-sterol reductase Source.52: DFBPPR6306 ---- Plant proteins ---- NADP-dependent glyceraldehyde-3-phosphate dehydrogenase Source.53: DFBPPR6343 ---- Plant proteins ---- Aspartate carbamoyltransferase 3, chloroplastic Source.54: DFBPPR6344 ---- Plant proteins ---- Aspartate carbamoyltransferase 2, chloroplastic Source.55: DFBPPR6347 ---- Plant proteins ---- Granule-bound starch synthase 2, chloroplastic/amyloplastic Source.56: DFBPPR6636 ---- Plant proteins ---- NADP-dependent glyceraldehyde-3-phosphate dehydrogenase Source.57: DFBPPR6774 ---- Plant proteins ---- Eukaryotic translation initiation factor 4E-1 Source.58: DFBPPR7638 ---- Milk proteins ---- Tissue-type plasminogen activator Source.59: DFBPPR7643 ---- Milk proteins ---- MICAL-like protein 1 Source.60: DFBPPR8371 ---- Plant proteins ---- NADP-dependent glyceraldehyde-3-phosphate dehydrogenase Source.61: DFBPPR8501 ---- Milk proteins ---- Platelet glycoprotein 4 Source.62: DFBPPR8518 ---- Milk proteins ---- MICAL-like protein 1 Source.63: DFBPPR15976 ---- Animal proteins ---- T-box transcription factor T Source.64: DFBPPR16054 ---- Animal proteins ---- Hepatocyte growth factor receptor Source.65: DFBPPR16055 ---- Animal proteins ---- Glutamate receptor ionotropic, NMDA 2B Source.66: DFBPPR16085 ---- Animal proteins ---- Guanine nucleotide-binding protein G(i) subunit alpha-2 Source.67: DFBPPR16115 ---- Animal proteins ---- Guanine nucleotide-binding protein G(t) subunit alpha-1 Source.68: DFBPPR16174 ---- Animal proteins ---- Guanine nucleotide-binding protein G(q) subunit alpha Source.69: DFBPPR16515 ---- Animal proteins ---- Guanine nucleotide-binding protein subunit alpha-11 Source.70: DFBPPR16523 ---- Animal proteins ---- Hepatocyte growth factor activator Source.71: DFBPPR16747 ---- Animal proteins ---- Pleckstrin Source.72: DFBPPR16773 ---- Animal proteins ---- Hemoglobin subunit alpha-A Source.73: DFBPPR16895 ---- Animal proteins ---- Coagulation factor VII Source.74: DFBPPR16925 ---- Animal proteins ---- Supervillin Source.75: DFBPPR16953 ---- Animal proteins ---- Activin receptor type-2A Source.76: DFBPPR17025 ---- Animal proteins ---- Tissue-type plasminogen activator Source.77: DFBPPR17042 ---- Animal proteins ---- Guanine nucleotide-binding protein G(i) subunit alpha-1 Source.78: DFBPPR17049 ---- Animal proteins ---- cGMP-dependent 3',5'-cyclic phosphodiesterase Source.79: DFBPPR17066 ---- Animal proteins ---- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Source.80: DFBPPR17093 ---- Animal proteins ---- Guanine nucleotide-binding protein G(t) subunit alpha-2 Source.81: DFBPPR17118 ---- Animal proteins ---- Guanine nucleotide-binding protein G(t) subunit alpha-1 Source.82: DFBPPR17131 ---- Animal proteins ---- Hepatocyte growth factor receptor Source.83: DFBPPR17170 ---- Animal proteins ---- A disintegrin and metalloproteinase with thrombospondin motifs 2 Source.84: DFBPPR17487 ---- Animal proteins ---- Leucine-rich repeat-containing G-protein coupled receptor 4 Source.85: DFBPPR17498 ---- Animal proteins ---- Guanine nucleotide-binding protein G(o) subunit alpha Source.86: DFBPPR17659 ---- Animal proteins ---- Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B Source.87: DFBPPR17900 ---- Animal proteins ---- Acetyl-CoA carboxylase 1 Source.88: DFBPPR17965 ---- Animal proteins ---- Guanine nucleotide-binding protein subunit alpha-11 Source.89: DFBPPR18043 ---- Animal proteins ---- Polypeptide N-acetylgalactosaminyltransferase 6 Source.90: DFBPPR18089 ---- Animal proteins ---- Coatomer subunit delta Source.91: DFBPPR18091 ---- Animal proteins ---- Urokinase-type plasminogen activator Source.92: DFBPPR18117 ---- Animal proteins ---- Matrix metalloproteinase-23 Source.93: DFBPPR18236 ---- Animal proteins ---- Latent-transforming growth factor beta-binding protein 2 Source.94: DFBPPR18248 ---- Animal proteins ---- DnaJ homolog subfamily C member 3 Source.95: DFBPPR18269 ---- Animal proteins ---- Coagulation factor XI Source.96: DFBPPR18357 ---- Animal proteins ---- Phosphatidylethanolamine N-methyltransferase Source.97: DFBPPR18413 ---- Animal proteins ---- Zinc finger protein Aiolos Source.98: DFBPPR18415 ---- Animal proteins ---- Guanine nucleotide-binding protein subunit alpha-14 Source.99: DFBPPR18422 ---- Animal proteins ---- Endonuclease III-like protein 1 Source.100: DFBPPR18481 ---- Animal proteins ---- Plasma kallikrein Source.101: DFBPPR18606 ---- Animal proteins ---- Transcriptional repressor NF-X1 Source.102: DFBPPR18703 ---- Animal proteins ---- Thialysine N-epsilon-acetyltransferase Source.103: DFBPPR18717 ---- Animal proteins ---- Pituitary adenylate cyclase-activating polypeptide type I receptor Source.104: DFBPPR18840 ---- Animal proteins ---- NEDD8-conjugating enzyme UBE2F Source.105: DFBPPR18948 ---- Animal proteins ---- Probable tubulin polyglutamylase TTLL1 Source.106: DFBPPR19002 ---- Animal proteins ---- Mitochondrial basic amino acids transporter Source.107: DFBPPR19050 ---- Animal proteins ---- Tripartite motif-containing protein 2 Source.108: DFBPPR19058 ---- Animal proteins ---- Phosphatidylserine decarboxylase proenzyme, mitochondrial Source.109: DFBPPR19110 ---- Animal proteins ---- Trimeric intracellular cation channel type B Source.110: DFBPPR19119 ---- Animal proteins ---- Phospholipase D2 Source.111: DFBPPR19161 ---- Animal proteins ---- Anaphase-promoting complex subunit 11 Source.112: DFBPPR19170 ---- Animal proteins ---- Isoaspartyl peptidase/L-asparaginase Source.113: DFBPPR19216 ---- Animal proteins ---- Cysteine protease ATG4B Source.114: DFBPPR19260 ---- Animal proteins ---- rRNA N6-adenosine-methyltransferase ZCCHC4 Source.115: DFBPPR19420 ---- Animal proteins ---- Peripheral myelin protein 22 Source.116: DFBPPR19449 ---- Animal proteins ---- SCO-spondin Source.117: DFBPPR19500 ---- Animal proteins ---- Complement C2 Source.118: DFBPPR19556 ---- Animal proteins ---- Suppressor of tumorigenicity 14 protein homolog Source.119: DFBPPR19735 ---- Animal proteins ---- Complement component C7 Source.120: DFBPPR19743 ---- Animal proteins ---- C-X-C motif chemokine 16 Source.121: DFBPPR19902 ---- Animal proteins ---- Trimeric intracellular cation channel type A Source.122: DFBPPR19961 ---- Animal proteins ---- Sulfate transporter Source.123: DFBPPR20201 ---- Animal proteins ---- PDZ and LIM domain protein 7 Source.124: DFBPPR20218 ---- Animal proteins ---- Probable tubulin polyglutamylase TTLL9 Source.125: DFBPPR20354 ---- Animal proteins ---- Single-strand selective monofunctional uracil DNA glycosylase Source.126: DFBPPR20453 ---- Animal proteins ---- Cysteine dioxygenase type 1 Source.127: DFBPPR20454 ---- Animal proteins ---- DNA polymerase delta subunit 2 Source.128: DFBPPR20609 ---- Animal proteins ---- Ran-binding protein 10 Source.129: DFBPPR20795 ---- Animal proteins ---- Four and a half LIM domains protein 3 Source.130: DFBPPR20859 ---- Animal proteins ---- Trafficking protein particle complex subunit 4 Source.131: DFBPPR20863 ---- Animal proteins ---- LIM and senescent cell antigen-like-containing domain protein 2 Source.132: DFBPPR20870 ---- Animal proteins ---- HMG box-containing protein 1 Source.133: DFBPPR20899 ---- Animal proteins ---- Centrosomal protein kizuna Source.134: DFBPPR21191 ---- Animal proteins ---- RAS protein activator like-3 Source.135: DFBPPR21483 ---- Animal proteins ---- F-box/LRR-repeat protein 8 Source.136: DFBPPR21662 ---- Animal proteins ---- Ornithine decarboxylase antizyme 1 Source.137: DFBPPR21666 ---- Animal proteins ---- Importin-13 Source.138: DFBPPR21728 ---- Animal proteins ---- Galectin-9 Source.139: DFBPPR21950 ---- Animal proteins ---- Solute carrier family 25 member 48 Source.140: DFBPPR22047 ---- Animal proteins ---- WD repeat-containing protein 6 Source.141: DFBPPR22097 ---- Animal proteins ---- Ester hydrolase C11orf54 homolog Source.142: DFBPPR22252 ---- Animal proteins ---- Glutamine amidotransferase-like class 1 domain-containing protein 1 Source.143: DFBPPR22279 ---- Animal proteins ---- THUMP domain-containing protein 3 Source.144: DFBPPR22406 ---- Animal proteins ---- Uncharacterized protein KIAA2013 homolog Source.145: DFBPPR22473 ---- Animal proteins ---- BTB/POZ domain-containing protein KCTD19 Source.146: DFBPPR22680 ---- Animal proteins ---- Proline-rich protein 32 Source.147: DFBPPR8649 ---- Animal proteins ---- Acrosin Source.148: DFBPPR8740 ---- Animal proteins ---- Hepatocyte growth factor receptor Source.149: DFBPPR8819 ---- Animal proteins ---- H(+)/Cl(-) exchange transporter 5 Source.150: DFBPPR8847 ---- Animal proteins ---- Guanine nucleotide-binding protein G(q) subunit alpha Source.151: DFBPPR9107 ---- Animal proteins ---- Tissue-type plasminogen activator Source.152: DFBPPR9211 ---- Animal proteins ---- Urokinase-type plasminogen activator Source.153: DFBPPR9246 ---- Animal proteins ---- LIM/homeobox protein Lhx3 Source.154: DFBPPR9278 ---- Animal proteins ---- Guanine nucleotide-binding protein subunit alpha-11 Source.155: DFBPPR9306 ---- Animal proteins ---- Complement component C7 Source.156: DFBPPR9404 ---- Animal proteins ---- Tryptase Source.157: DFBPPR9583 ---- Animal proteins ---- Protocadherin-11 X-linked Source.158: DFBPPR10036 ---- Animal proteins ---- Acetyl-CoA carboxylase Source.159: DFBPPR10039 ---- Animal proteins ---- Activin receptor type-2A Source.160: DFBPPR10089 ---- Animal proteins ---- Lysyl oxidase homolog 2 Source.161: DFBPPR10138 ---- Animal proteins ---- Epidermal growth factor receptor Source.162: DFBPPR10173 ---- Animal proteins ---- Teneurin-1 Source.163: DFBPPR10178 ---- Animal proteins ---- Homeobox protein SIX3 Source.164: DFBPPR10180 ---- Animal proteins ---- Teneurin-2 Source.165: DFBPPR10303 ---- Animal proteins ---- Guanine nucleotide-binding protein G(i) subunit alpha-1 Source.166: DFBPPR10393 ---- Animal proteins ---- Vitellogenin-1 Source.167: DFBPPR10422 ---- Animal proteins ---- Collagen alpha-1(XII) chain Source.168: DFBPPR10425 ---- Animal proteins ---- Fanconi anemia group J protein homolog Source.169: DFBPPR10487 ---- Animal proteins ---- Guanine nucleotide-binding protein G(i) subunit alpha-2 Source.170: DFBPPR10512 ---- Animal proteins ---- Collagen alpha-1(XIV) chain Source.171: DFBPPR10742 ---- Animal proteins ---- LIM/homeobox protein Lhx3 Source.172: DFBPPR10762 ---- Animal proteins ---- Cadherin-6 Source.173: DFBPPR10809 ---- Animal proteins ---- Lysine-specific demethylase 3A Source.174: DFBPPR10850 ---- Animal proteins ---- Ovostatin Source.175: DFBPPR10937 ---- Animal proteins ---- Urokinase-type plasminogen activator Source.176: DFBPPR11171 ---- Animal proteins ---- Coatomer subunit delta Source.177: DFBPPR11193 ---- Animal proteins ---- Gallinacin-8 Source.178: DFBPPR11228 ---- Animal proteins ---- CTP synthase 2 Source.179: DFBPPR11262 ---- Animal proteins ---- Cysteine protease ATG4B Source.180: DFBPPR11434 ---- Animal proteins ---- Homeobox protein SIX6 Source.181: DFBPPR11609 ---- Animal proteins ---- Trimeric intracellular cation channel type A Source.182: DFBPPR11681 ---- Animal proteins ---- Ornithine decarboxylase antizyme 1 Source.183: DFBPPR11745 ---- Animal proteins ---- Digestive organ expansion factor homolog Source.184: DFBPPR11753 ---- Animal proteins ---- Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Source.185: DFBPPR11789 ---- Animal proteins ---- NF-kappa-B inhibitor-interacting Ras-like protein 2 Source.186: DFBPPR11820 ---- Animal proteins ---- Lipoma-preferred partner homolog Source.187: DFBPPR11901 ---- Animal proteins ---- Zinc finger CCHC domain-containing protein 8 Source.188: DFBPPR11909 ---- Animal proteins ---- Cysteine protease ATG4A Source.189: DFBPPR12055 ---- Animal proteins ---- Importin-13 Source.190: DFBPPR12343 ---- Animal proteins ---- Protein SLFN14 Source.191: DFBPPR12423 ---- Animal proteins ---- Hepatocyte growth factor receptor Source.192: DFBPPR12464 ---- Animal proteins ---- Urokinase-type plasminogen activator Source.193: DFBPPR12525 ---- Animal proteins ---- Coagulation factor VII Source.194: DFBPPR12557 ---- Animal proteins ---- Acrosin Source.195: DFBPPR12609 ---- Animal proteins ---- Trimeric intracellular cation channel type A Source.196: DFBPPR13171 ---- Animal proteins ---- Hepatocyte growth factor receptor Source.197: DFBPPR13340 ---- Animal proteins ---- Sulfate transporter Source.198: DFBPPR13585 ---- Animal proteins ---- Hepatocyte growth factor receptor Source.199: DFBPPR13602 ---- Animal proteins ---- Acrosin Source.200: DFBPPR13603 ---- Animal proteins ---- Acetyl-CoA carboxylase 1 Source.201: DFBPPR13644 ---- Animal proteins ---- Activin receptor type-2A Source.202: DFBPPR14123 ---- Marine protein ---- Albumin 1 Source.203: DFBPPR14124 ---- Marine protein ---- Albumin 2 Source.204: DFBPPR14250 ---- Marine protein ---- Vasotocin-neurophysin VT 2 Source.205: DFBPPR14791 ---- Marine protein ---- Guanine nucleotide-binding protein G(i) subunit alpha Source.206: DFBPPR14796 ---- Marine protein ---- Guanine nucleotide-binding protein G(q) subunit alpha Source.207: DFBPPR14883 ---- Microorganism protein ---- Guanine nucleotide-binding protein alpha-2 subunit Source.208: DFBPPR14885 ---- Microorganism protein ---- Guanine nucleotide-binding protein alpha-1 subunit Source.209: DFBPPR14984 ---- Microorganism protein ---- Alpha-1,3/1,6-mannosyltransferase ALG2 Source.210: DFBPPR15226 ---- Microorganism protein ---- GPI mannosyltransferase 4 Source.211: DFBPPR15467 ---- Microorganism protein ---- Serine/threonine-protein phosphatase 4 regulatory subunit 3 Source.212: DFBPPR15494 ---- Microorganism protein ---- Protein STU1 Source.213: DFBPPR15499 ---- Microorganism protein ---- Mediator of RNA polymerase II transcription subunit 12 Source.214: DFBPPR15512 ---- Microorganism protein ---- Vacuolar membrane-associated protein IML1 Source.215: DFBPPR0008 ---- Plant protein ---- Gamma conglutin 2 Source.216: DFBPPR7811 ---- Plant protein ---- Fatty acid desaturase DES2
Link-research Inductive analysis	There are no literature reports on the discovery of this sequence in other food-source proteins.

Biological/Functional activity & target protein

Antithrombotic activity	The peptide could potently prolonged the thrombin time (TT) and the activated partial thromboplastin time (APTT) in a dose-dependant manner. This result implies that the peptide extracts inhibit coagulation factors such as FXIIa, FXIa, tenase components (FIXa, FVIIIa, FX, Ca2+, phospholipids) in the intrinsic blood coagulation pathway ^[2].
Specific target protein(s)	Specific Target Protein(s): Coagulation factor IX Coagulation factor VIII Coagulation factor X Coagulation factor XI Coagulation factor XII

Taste properties & Structure

Bitterness

Literature report	N.D
Bitter prediction tools	Bitter taste ^prediction

SMILES

N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O

Preparation method

Mode of preparation	Enzymatic hydrolysis
Enzyme(s)/starter culture	The hydrolysate generated by the crude protease from Bacillus licheniformis NH1 displayed the highest anticoagulant activity.

Stability & Cytotoxicity

Peptide stability

Literature report:	N.D
EHP-Tool:	Enzymatic Hydrolysis Prediction Tool (EHP-Tool)

Peptide cytotoxicity

Literature report:	N.D
Prediction:	ToxinPred

Additional information

Goby protein hydrolysates may potentially serve as a good source of anticoagulant peptides that could be utilised to develop functional foods for thrombosis prevention.

Database cross-references

[D1]

[D2]

[D3]

[D4]

Reference(s)

Primary literature	Nasri, R., Amor, I.B., Bougatef, A., Nedjar-Arroume, N., Dhulster, P., Gargouri, J., et al. Anticoagulant activities of goby muscle protein hydrolysates. Food Chem. 2012, 133, 835-41. DOI: 10.1016/j.foodchem.2012.01.101
Other literature(s)	[1] Cheng, S., et al., Food-derived antithrombotic peptides: Preparation, identification, and interactions with thrombin. Crit Rev Food Sci Nutr, 2019: p. 1-15. [2] Jo H Y , Jung W K , Kim S K . Purification and characterization of a novel anticoagulant peptide from marine echiuroid worm, Urechis unicinctus[J]. Process Biochemistry, 2008, 43(2):179-184.
PubDate	2012